***budesonida inhalada en dosis de 800 µg/día por seis o más meses, se asoció con alteración de la respuesta del eje hipotálamo-hipófisis-suprarrenal a la estimulación con ACTH en 3 de 20 niños asmáticos severos.

Consider asthma if any of the following signs or symptoms are present: Frequent episodes of wheezing—more than once a month.

Activity-induced cough or wheeze. Cough particularly at night during periods without viral infections. Absence of seasonal variation in wheeze. Symptoms that persist after age 3. Symptoms occur or worsen in the presence of:

• Aeroallergens (house dust mites, companion animals, cockroach, fungi) • Exercise • Pollen • Respiratory (viral) infections• Strong emotional expression• Tobacco smoke The child’s colds repeatedly “go to the chest” or take more than 10 days to clear up.

Symptoms improve when asthma medication is given.