Nano Materials Nano Science Nano Technology - … Calit2 11-10-11.pdf · Nano Materials Philip G....

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Nano Materials

Philip G. CollinsDept. of Physics and Astronomy

Nano Science

Nano Technology

Nanomaterials are not New

Prof. A. Belcher, MIT

Our Ability to “See” at the Nanoscale

AFM

SEM TEM

STM

NSOM

EFM

Nanospheres as Lubricants & Coatings

Nanofibers for Fabrics & Composites

Nanowires for Electronic Circuits

Early Nanotechnologies of Today

• composites• coatings• lubricants• fabrics• enhanced plastics

Early Nanotechnologies of Today

• composites• coatings• lubricants• fabrics• enhanced plastics

Advanced Nanotechnologies of the Future• motors• robots

• communicators• control systems

Science Fiction to Science Facts

1999

2010

What Do You Build with the World’s Smallest Wires?

Circuits of Single Molecules?

V

Single Molecule Circuits

Watching Protein Binding

Single Molecule Circuits

T4 Lysozyme (enzyme)

Peptidoglycan(substrate)

Watching Enzyme Activity

Single Molecule Circuits

Understanding Mutations and Inhibitors

S90C K83A

K83A/R119A

R119A

K83E/R119A K83A/R119E

T26E/S90C S36C E11H/Nterm Posi tive charge

Negative charge

Neutral charge

Tethered site

Cata lytic site

Nano Materials

Philip G. CollinsDept. of Physics and Astronomy

Nano Science

Nano Technology