Starting the precision � diabetes � management ageeFollowup—Dynamic � management � of � glucose � metabolism
Vincent � Yang, CEOZion � China � Ltd.
http://www.zionchina.com
Zion China technology Ltd. (健安华夏)
n Zion � China � Technology � Co., � Ltd. � – Zion � China � Technology � Co., � Ltd. � (Beijing) � was � established � in � Beijing's � Zhongguancun High-
Tech � Park � in � 2013. � – The � core � team � has � strong � background � in � healthcare � informatics, � diabetes � market � and � medical �
background. � – We � focus � on � Precision � Diabetes � Management � through � innovation � in � IT � and � AI � technology. � � – We � created � Kinetics � of � Glucose � Metabolism � model � to � empower � patient � to � manage � diabetes �
using � individualized � assessment, � analysis � and � advice � for � medicine, � diet, � exercise � and � lifestyle.
健安华夏(北京)科技有限公司
赋能中国糖友,享受健康生活!Empower every diabetes patient to enjoy a healthy life!
Standard:•Transform the standardof Precision DiabetesManagement throughthe Kinetics of Glucose Metabolism model.
Technology:•Develop scalable IT and AI technology, to makeup for the deficiency ofresources for family doctors and caregivers.
Ecosystem:•Promote an ecosystemof services, products, and providers for every need around diabetes and chronic diseases.
Service:•Build a #1 brand for Precision DiabetesManagement service.
Core � team: � serial entrepreneurship+10 � yrs Healthcare
健安华夏(北京)科技有限公司
CEO: Vincent � Yang � 杨枫: Advisor � for � Senior � Care � Informatics � Standard Body � of � Ministry � of � Civic � Affairs. � 12 � years � veterans � in � Microsoft, � specialty in � large � scale � internet � database � and � BI. � Developed � Microsoft � Balance � Scorecards V1, � Formal � Senior � Architecture � Evangelist � Lead � for � Greater � China � Region.Founded � Promising � China � in � 2008, � acquired � by � iSoftstone Inc. � in � 2011. � � VP � CTO � for � iHealthstone, � Founded � Zion � China � Ltd. � In � 2013. � Invented � precision � diabetes � management � model � using � Kinetics � of � Glucose � Metabolism � data � model.
Co-founder, � COO: � Rita � Zhou 周茜: Finance and � Accounting � University � of � Texas � at � DallasPrevious experience � include � account � information � certification � in � TD � Ameritrade � US and � marketing � leader � for � a � Online-2-Offline � startup � under � 3W � Coffee incubator.Experience in � China � healthcare � marketing � channel, � lead � a � project � on � medical � devices � import.
Co-founder, � Chief Medical � Officer : � Shui Xi, � MD, � 奚水From � Beijing � United � Medical � School � Hospital. � Post � Dr. � in � Ministry � of � Health � Research � Institute. � � Previously � worked � in � 301 � hospital, specializes � in � gynecological � endocrinology, � gestational � diabetes, � infertility, � diagnosis � and � treatment � of � menopause-related � diseases.
Board Advisors: Dr. Jin Ma, 马今, MA in Cardiovascular Medicine and MBASenior marketing expert and investor with 14 years executive experiences in an pharmaceutical market.Previous senior executive in Bayer, in charge of the largest diabetes medicine in China with $3B annualsale. In 2014 founded China's first vertical healthcare innovation Accelerator - Archimedes (Beijing)medical Technology Co., Ltd. and served as Executive Director and CEO .
Core IT team: long track of development and field experience in China healthcare informatics, and over10,000 hours of experience in chronicle disease management.Previous experience include a Clinical Trial by MOH, MS and GE on tele-medicine collaboration system inrural area, data warehouse integration project for Beijing United Medical School Hospital, sole reseller ofMicrosoft Healtvault in China.
Diabetes � in � China: � crisis � and � opportunities �
健安华夏(北京)科技有限公司
147M � Patients
51.2% � (500M)Pre-diabetes
15% � Gestational � Diabetes
Only 10.2% � is under � control
1-10 yrs lost � in � life � expectancy
13% � in � total � healthcare � cost
No � family � doctors / GP
Less � than � 20K � Endocrinologists
Poor � compliance � in � patients
Insulin � Pump � and � CMGS rarelyused
Little ecosystem for services andproducts
Not � enough � money � from � Gov.
CrisisCrisis
Healthcare � (Diabetes):$45~75BWellness (Diabetes):$150~600B
Microsoft
V2 Traditional MeterOnly measures at fixed time and static data
V3 CGMSContinuous, 1 reading per 3 mins, 480 per day, 3360 per 7 days
V4 Machine Learning (AI)Machine Learning. Predicts, Analyzes and Gives personalized advice
Diabetes � Management � 4.0
eFollowup—Kinetics � of � glucose � metabolism
*Correct lifelong � user behavior errors*
Balanced � nutrition diet
Reduce � volatility
Reduced � HbA1c
Prevent � hypoglycemia
eFollowupAPP CGMS
Diet Nutritiondatabase
Kinetics of glucose
metabolism
Diabetes � management � gold � standard: � glycosylated � hemoglobin � decreased � by � 1% each, � diabetes � related � mortality � can � be � reduced � by � 21%, � incidence � of � myocardial � infarction � was � decreased � by � 14%, � stroke � incidence � decreased � 12%, � microvascular � disease � incidence � decreased � by � 37%, � cataract � surgery � was � reduced � by � 19%, � 43% � decrease � in � the � peripheral � vascular � disease � leading � to � amputation � or � death, � heart � failure � rate � decreased � by � 16%.
Be � aware: � Blood � Glucose � is � just � an � indicator, � not � end � goal!
V1 � product: � 7 � days � of � CGMS profiling test � ►►►Kinetic � report � of � glucose � metabolism
Zion China Technology Ltd.
7 � days(once
per year)
Glucose � Metabolism � Data � Model
健安华夏(北京)科技有限公司
Monitoring•Continuous Glucose �
monitoring � for � 7x24•Record of � medication, � diet, �
exercise � and � behavior � data
Analysis•Data � model � of � Glucose � curve
trend•Rate � of � in target, � risks � of �
hyperglycemia � & � hypoglycemia.
Customize•Individualized � diabetes
management � plans.•Individualized nutrition � diet �
plan.
健安华夏(北京)科技有限公司
Empower � Self:Visual ►► Results ►► Achievement
健安华夏(北京)科技有限公司
Scorecard
I never knew we cansee myglucose thisway!
Very useful, now Iunderstood a lot.Thanks!
Personalized � recipe � (Case): � individualized � recipes � proven � by � 7 � days � test
健安华夏(北京)科技有限公司
第1天 第2天 第3天 第4天 第5天 第6天 第7天
鸡蛋50g 麦片50g 馒头100g 鸡蛋50g 鸡蛋50g 燕麦50g 生面条60g
燕麦片50g 牛奶200ml绿豆(薏米、小米
、玉米)粥200g燕麦片50g 牛奶200ml 豆浆200ml
牛奶200ml 牛奶200ml
香肠72g 北京烤鸭100g 米饭150g 主食150g 米饭100g炒鸡蛋、豆腐
200g;主食150g
大米饭150g 主食150g 蔬菜200g 蔬菜200g 木耳炒肉100g 鸡脯肉237g; 蔬菜200g
油菜290g 鱼、肉100g 豆、肉类100g 蔬菜200g 米饭150g 肉类100g
加餐 坚果20g 柑橘200g 柚子100g 坚果20g 核桃20g 鱿鱼仔100g 橘子200g
苹果72g蔬菜(海带)
300g主食150g 主食150g 柚子100g 水煮蔬菜300g 无糖饼干50g
主食150g 肝脏25g 蔬菜200g 蔬菜200g 肉丝面100g 柚子100g 蔬菜200g
蔬菜200g 主食150g 鱼、肉75g 豆、肉类75g 蔬菜100g 豆、肉类75g
运动 散步30分钟 散步30分钟 散步30分钟 散步30分钟 散步30分钟 中度运动60分钟 散步30分钟
早饭
午饭
晚饭
PAGEReference � cases:HbA1C:7.6% � ►► 6.4% � ►► 6.1% � (-15% � in � medication) Small � quantized � data, � big � data � recommendation
Predictable, � autonomous � controllable Balanced � health, � free � enjoyment, � eating � ecosystem健安华夏(北京)科技有限公司
Zion � China-Microsoft � Azure � Machine � Learning � on � diabetes
Apple-Beijing � Xuan � Wu � Hospital
2015.3
HealthKits
IBM-Medtronic
2016.1
CES Show
Google � AlphaGO
2016.4
On Healthcare
Zion � China
2016.4
Azure Machine � Learning
健安华夏(北京)科技有限公司
Azure Machine Learning: Partnership between industry leaders
Dr. Robert discusses interpretation of blood glucose data with Dr. Tianchuan (Michael) Du at the Microsoft Silicon Valley campus in Mountain View California.
DX China Technical Evangelist working with ZionChina team.
Cloud Ideation discussion between TE team and ZionChina.
Working as one team.
CEO&行业专家
Hyperglycemia: 4-6 hours prediction based on 30 minutes glucose trend. Will sound alarm or give advice based on results
Hypoglycemia: discover patterns based on personal glycaemia history and behaviors habits. Possible intervention advises to avoid them.
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2016/1/19 6:142016/1/19 6:432016/1/19 7:122016/1/19 7:402016/1/19 8:092016/1/19 8:382016/1/19 9:072016/1/19 9:362016/1/19 10:042016/1/19 10:332016/1/19 11:022016/1/19 11:31
Machine Learning on glucose prediction
Human workflow
Machine Learning
健安华夏(北京)科技有限公司
Zion China has this vision of how to improve the lives of 147M+ Chinese who suffer from diabetes. In fact, diabetes is a world-‐wide epidemic. And to have the ability now to continuously monitor your glucose levels, but not just the glucose levels but to be able to look at all the other data, your exercise, your food intake, and then in the end bring to you a much more proactive diabetes management, so that your own quality of life can improve. Think about the impact it will have on the people in China, the health care cost, as well as the impact it can have on the world.
-- Microsoft CEO Satya Nadella @2016 Developer Summit
2016 Developer Summit
⭐ Gold � Award � for � Senior � Care � Startup � Competition � by � Ministry � of � Civic � Affairs
⭐ First � Partners � in � Healthcare � for � Microsoft � Azure � Machine � Learning
⭐ Big � Data � forums � for � 8th China � Cloud � Computing � Conference
⭐ Champion � in � Aging2.0 � International � Competition � – Beijing � Area
⭐ Most � popular � products � award � for � Aging2.0 � International � Competition � – Beijing � Area
⭐ Gold � Award � of � Pan � Asia � Medical � Habitation � Competition � – Beijing
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