ZionChina, Care, Beijing (China)

Starting the precision � diabetes � management ageeFollowup—Dynamic � management � of � glucose � metabolism

Vincent � Yang, CEOZion � China � Ltd.

http://www.zionchina.com

Zion China technology Ltd. (健安华夏)

n Zion � China � Technology � Co., � Ltd. � – Zion � China � Technology � Co., � Ltd. � (Beijing) � was � established � in � Beijing's � Zhongguancun High-

Tech � Park � in � 2013. � – The � core � team � has � strong � background � in � healthcare � informatics, � diabetes � market � and � medical �

background. � – We � focus � on � Precision � Diabetes � Management � through � innovation � in � IT � and � AI � technology. � � – We � created � Kinetics � of � Glucose � Metabolism � model � to � empower � patient � to � manage � diabetes �

using � individualized � assessment, � analysis � and � advice � for � medicine, � diet, � exercise � and � lifestyle.

健安华夏（北京）科技有限公司

赋能中国糖友，享受健康生活！Empower every diabetes patient to enjoy a healthy life!

Standard:•Transform the standardof Precision DiabetesManagement throughthe Kinetics of Glucose Metabolism model.

Technology:•Develop scalable IT and AI technology, to makeup for the deficiency ofresources for family doctors and caregivers.

Ecosystem:•Promote an ecosystemof services, products, and providers for every need around diabetes and chronic diseases.

Service:•Build a #1 brand for Precision DiabetesManagement service.

Core � team: � serial entrepreneurship+10 � yrs Healthcare


CEO: Vincent � Yang � 杨枫: Advisor � for � Senior � Care � Informatics � Standard Body � of � Ministry � of � Civic � Affairs. � 12 � years � veterans � in � Microsoft, � specialty in � large � scale � internet � database � and � BI. � Developed � Microsoft � Balance � Scorecards V1, � Formal � Senior � Architecture � Evangelist � Lead � for � Greater � China � Region.Founded � Promising � China � in � 2008, � acquired � by � iSoftstone Inc. � in � 2011. � � VP � CTO � for � iHealthstone, � Founded � Zion � China � Ltd. � In � 2013. � Invented � precision � diabetes � management � model � using � Kinetics � of � Glucose � Metabolism � data � model.

Co-founder, � COO: � Rita � Zhou 周茜: Finance and � Accounting � University � of � Texas � at � DallasPrevious experience � include � account � information � certification � in � TD � Ameritrade � US and � marketing � leader � for � a � Online-2-Offline � startup � under � 3W � Coffee incubator.Experience in � China � healthcare � marketing � channel, � lead � a � project � on � medical � devices � import.

Co-founder, � Chief Medical � Officer : � Shui Xi, � MD, � 奚水From � Beijing � United � Medical � School � Hospital. � Post � Dr. � in � Ministry � of � Health � Research � Institute. � � Previously � worked � in � 301 � hospital, specializes � in � gynecological � endocrinology, � gestational � diabetes, � infertility, � diagnosis � and � treatment � of � menopause-related � diseases.

Board Advisors: Dr. Jin Ma, 马今, MA in Cardiovascular Medicine and MBASenior marketing expert and investor with 14 years executive experiences in an pharmaceutical market.Previous senior executive in Bayer, in charge of the largest diabetes medicine in China with $3B annualsale. In 2014 founded China's first vertical healthcare innovation Accelerator - Archimedes (Beijing)medical Technology Co., Ltd. and served as Executive Director and CEO .

Core IT team: long track of development and field experience in China healthcare informatics, and over10,000 hours of experience in chronicle disease management.Previous experience include a Clinical Trial by MOH, MS and GE on tele-medicine collaboration system inrural area, data warehouse integration project for Beijing United Medical School Hospital, sole reseller ofMicrosoft Healtvault in China.

Diabetes � in � China: � crisis � and � opportunities �


147M � Patients

51.2% � （500M）Pre-diabetes

15% � Gestational � Diabetes

Only 10.2% � is under � control

1-10 yrs lost � in � life � expectancy

13% � in � total � healthcare � cost

No � family � doctors / GP

Less � than � 20K � Endocrinologists

Poor � compliance � in � patients

Insulin � Pump � and � CMGS rarelyused

Little ecosystem for services andproducts

Not � enough � money � from � Gov.

CrisisCrisis

Healthcare � (Diabetes)：$45~75BWellness (Diabetes)：$150~600B

Microsoft

V2 Traditional MeterOnly measures at fixed time and static data

V3 CGMSContinuous, 1 reading per 3 mins, 480 per day, 3360 per 7 days

V4 Machine Learning (AI)Machine Learning. Predicts, Analyzes and Gives personalized advice

Diabetes � Management � 4.0

eFollowup—Kinetics � of � glucose � metabolism

*Correct lifelong � user behavior errors*

Balanced � nutrition diet

Reduce � volatility

Reduced � HbA1c

Prevent � hypoglycemia

eFollowupAPP CGMS

Diet Nutritiondatabase

Kinetics of glucose

metabolism

Diabetes � management � gold � standard: � glycosylated � hemoglobin � decreased � by � 1% each, � diabetes � related � mortality � can � be � reduced � by � 21%, � incidence � of � myocardial � infarction � was � decreased � by � 14%, � stroke � incidence � decreased � 12%, � microvascular � disease � incidence � decreased � by � 37%, � cataract � surgery � was � reduced � by � 19%, � 43% � decrease � in � the � peripheral � vascular � disease � leading � to � amputation � or � death, � heart � failure � rate � decreased � by � 16%.

Be � aware: � Blood � Glucose � is � just � an � indicator, � not � end � goal!

V1 � product: � 7 � days � of � CGMS profiling test � ►►►Kinetic � report � of � glucose � metabolism

Zion China Technology Ltd.

7 � days(once

per year)

Glucose � Metabolism � Data � Model


Monitoring•Continuous Glucose �

monitoring � for � 7x24•Record of � medication, � diet, �

exercise � and � behavior � data

Analysis•Data � model � of � Glucose � curve

trend•Rate � of � in target, � risks � of �

hyperglycemia � & � hypoglycemia.

Customize•Individualized � diabetes

management � plans.•Individualized nutrition � diet �

plan.

Empower � Self：Visual ►► Results ►► Achievement


Scorecard

I never knew we cansee myglucose thisway!

Very useful, now Iunderstood a lot.Thanks!

Personalized � recipe � (Case): � individualized � recipes � proven � by � 7 � days � test


第1天第2天第3天第4天第5天第6天第7天

鸡蛋50g 麦片50g 馒头100g 鸡蛋50g 鸡蛋50g 燕麦50g 生面条60g

燕麦片50g 牛奶200ml绿豆(薏米、小米

、玉米)粥200g燕麦片50g 牛奶200ml 豆浆200ml

牛奶200ml 牛奶200ml

香肠72g 北京烤鸭100g 米饭150g 主食150g 米饭100g炒鸡蛋、豆腐

200g；主食150g

大米饭150g 主食150g 蔬菜200g 蔬菜200g 木耳炒肉100g 鸡脯肉237g；蔬菜200g

油菜290g 鱼、肉100g 豆、肉类100g 蔬菜200g 米饭150g 肉类100g

加餐坚果20g 柑橘200g 柚子100g 坚果20g 核桃20g 鱿鱼仔100g 橘子200g

苹果72g蔬菜（海带）

300g主食150g 主食150g 柚子100g 水煮蔬菜300g 无糖饼干50g

主食150g 肝脏25g 蔬菜200g 蔬菜200g 肉丝面100g 柚子100g 蔬菜200g

蔬菜200g 主食150g 鱼、肉75g 豆、肉类75g 蔬菜100g 豆、肉类75g

运动散步30分钟散步30分钟散步30分钟散步30分钟散步30分钟中度运动60分钟散步30分钟

早饭

午饭

晚饭

PAGEReference � cases:HbA1C：7.6% � ►► 6.4% � ►► 6.1% � (-15% � in � medication) Small � quantized � data, � big � data � recommendation

Predictable, � autonomous � controllable Balanced � health, � free � enjoyment, � eating � ecosystem健安华夏（北京）科技有限公司

Zion � China-Microsoft � Azure � Machine � Learning � on � diabetes

Apple-Beijing � Xuan � Wu � Hospital

2015.3

HealthKits

IBM-Medtronic

2016.1

CES Show

Google � AlphaGO

2016.4

On Healthcare

Zion � China

2016.4

Azure Machine � Learning


Azure Machine Learning: Partnership between industry leaders

Dr. Robert discusses interpretation of blood glucose data with Dr. Tianchuan (Michael) Du at the Microsoft Silicon Valley campus in Mountain View California.

DX China Technical Evangelist working with ZionChina team.

Cloud Ideation discussion between TE team and ZionChina.

Working as one team.

CEO&行业专家

Hyperglycemia: 4-6 hours prediction based on 30 minutes glucose trend. Will sound alarm or give advice based on results

Hypoglycemia: discover patterns based on personal glycaemia history and behaviors habits. Possible intervention advises to avoid them.

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2016/1/19 6:142016/1/19 6:432016/1/19 7:122016/1/19 7:402016/1/19 8:092016/1/19 8:382016/1/19 9:072016/1/19 9:362016/1/19 10:042016/1/19 10:332016/1/19 11:022016/1/19 11:31

Machine Learning on glucose prediction

Human workflow

Machine Learning


Zion China has this vision of how to improve the lives of 147M+ Chinese who suffer from diabetes. In fact, diabetes is a world-‐wide epidemic. And to have the ability now to continuously monitor your glucose levels, but not just the glucose levels but to be able to look at all the other data, your exercise, your food intake, and then in the end bring to you a much more proactive diabetes management, so that your own quality of life can improve. Think about the impact it will have on the people in China, the health care cost, as well as the impact it can have on the world.

-- Microsoft CEO Satya Nadella @2016 Developer Summit

2016 Developer Summit

⭐ Gold � Award � for � Senior � Care � Startup � Competition � by � Ministry � of � Civic � Affairs

⭐ First � Partners � in � Healthcare � for � Microsoft � Azure � Machine � Learning

⭐ Big � Data � forums � for � 8th China � Cloud � Computing � Conference

⭐ Champion � in � Aging2.0 � International � Competition � – Beijing � Area

⭐ Most � popular � products � award � for � Aging2.0 � International � Competition � – Beijing � Area

⭐ Gold � Award � of � Pan � Asia � Medical � Habitation � Competition � – Beijing

WELCOME 18611602557

[email protected]

Vincent � Yang � 杨枫

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ZionChina, Care, Beijing (China)

Health & Medicine

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