1. Pre-ESRD 101427 1

2. Early-CKDPre-ESRD 2 3. ..95113b45(Pre-ESRD).100Early-CKD123a.1004.04Early-CKDPre-ESRD 3 4. 4 5. 1eGFR90 2eGFR 60~89.9CKD 3a eGFR 45~59.9 3b eGFR 30~44.9 4eGFR 15~29.9Pre-ESRD 5eGFR 15 5 6. (Early-CKD) 6 7. Early-CKD10011 Guideline eGFR() Upcr()LDL( )7 8. 90 8 9. 12:6(42e-learning):20%() 9 10. Urine protein/creatinineratio (UPCR) 1000 mg/gmeGFR45ml/min/1.73 m2Pre-ESRD(Stage 3b)2(180)110 11. CKDstage 2stage 1 eGFR(eGFR) 2 130/80 mmHg HbA1c7.0% (LDL)130 mg/dl ()11 12. 12 13. 250%21.CKDstage 2stage 12.eGFR(eGFR)2 140/90 mmHg130/80 mmHg HbA1c7.0%7.0% (LDL)130 mg/dl130 mg/dl ()1240013 14. 100112()(P4301C)200 /14,285,160(P4302C)200 / 5,502,900(P4303C)200/65,200 11,200 19,864,460:101.4.3100.01~1214 15. (1) CKD1CKD2CKD3a ABA/B18 417 2,026 3,1305,588 10,744 123,3668.7%63 416 1,937 4,1636,516 12,616 151,3068.3% 110 304 1,687 4,1115,902 11,700 73,295 16.0% 486 604 7,62016,201 18,709 42,530 61,282 69.4% 677 1,67113,27027,605 36,715 77,590 :1.101.2.16 100.01~12 2.10015 16. (2) 16 17. (3):VPN 17 18. (4) B A B/A 140/90 11,138 14.35%152413.7%mmHgHbA1c 7.0% 29,586 68.26% 22627.6%130 20,444 26.35%395219.3%(LDL) mg/dl 12,201 15.72%10238.4%1.101.2.162.(LDL)100(77,590)HbA1c43,3433.18 19. 1006771,67177,590() 13.7% HbA1c 7.6% (LDL)19.3% 8.4%10049CKD267419 20. Pre-ESRD20 21. 21 22. 22 23. (1) 12 (1) (2) (3)3123 24. (2) 123(Upcr < 200 mg/gm)4(180)124 25. P3402CStage 3b45111200P3403CStage 3b45311600P3404CP3403C11600 P3405CStage 3b4511600P3406C Stage 3b4Stage 3b4111500P3407C Stage 5Stage 5113000P3408C 111000P3409C Stage 3b451 12000 25 26. 9511-12 969798 9910051,969 49,898 59,894 44,12048,42084,0002,0348,492 40,861 66,61287,65299,215 3.91% 17.02% 68.22% 150.98% 181.03%118.11% (3)(3) (3)11001~3+42951195.963100% 26 27. 9511100Pre-ESRD 9511~1272128749 96 9,653409 10,062 9713,626382 14,008 9817,118676 17,794 9917,272617 17,889 100 17,683803 18,486 :(P3402C27 28. Pre-ESRD(). . Pre-ESRDeGFR ()100CKD Stage 3b45,7846% ()CKD Stage 52,229-2% ()363% 28 29. Pre-ESRD ()stage 5 96 97 98 99 (A)1891,0771,5751,989 (B )9,468 9,6639,74210,034 2.00%11.15%16.17% 19.82% (A/B)1.(A):(P3405C) 2.(1) ( ) ( 3 ) (2) 3 3. 29 4. (B) ( ID+ ) 30. Pre-ESRD ()% (A )(B ) = (B )/ (A )* 1 0 ^ 6 =( - )/ 95 2 2 ,8 7 6 ,5 2 79 ,0 3 8 3 9 5 .1 - 96 2 2 ,9 5 8 ,3 6 09 ,4 6 8 4 1 2 .44 .3 8 % 97 2 3 ,0 3 7 ,0 3 19 ,6 6 3 4 1 9 .51 .7 1 % 98 2 3 ,1 1 9 ,7 7 29 ,7 4 2 4 2 1 .40 .4 6 % 99 2 3 ,1 6 2 ,1 2 31 0 ,0 3 4 4 3 3 .22 .8 1 % 1 . (A ) ( ) 2 . (1 ) ( ) ( 3 ) (2 ) 3 3 . 4 . (B ) ( ID + ) 30 31. ..5 1.-2% 2.()15% 3.3% 4.14%31 32. 32