Med lez 5 glicolisi
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Transcript of Med lez 5 glicolisi
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CARBOIDRATI
Digestione e assorbimento dei glucidi
Glicolisi
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AMILOSIO
L’amilosio in acqua adotta
una conformazione
elicoidale.
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DISACCARIDI
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DIGESTIONE
• α-AMILASI SALIVARE
AZIONE BLANDA, rompe LEGAMI α,1-4
• α-AMILASI PANCREATICA
AZIONE FORTE, rompe LEGAMI α,1-4
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AMILASI
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OLIGO- e DI- SACCARASI
• ENZIMI PRESENTI SULLA MEMBRANA LUMINALE DELLE
CELLULE INTESTINALI
• OLIGO-1,6-GLUCOSIDASI
rompe LEGAMI αααα,1-6
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OLIGO- e DI-SACCARASI
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DI - SACCARASI
• SACCARASI GLUCOSIO + FRUTTOSIO
• LATTASI GALATTOSIO + GLUCOSIO
• MALTASI GLUCOSIO +GLUCOSIO
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Intolleranza al lattosio
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CELLULOSA
• POLISACCARIDE DEL GLUCOSIO
CON LEGAMI β β β β,1-4
• NON ESISTONO NELL’UOMO
ENZIMI CAPACI DI ROMPERE
DETTO LEGAME
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CELLULOSA
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GLUT5
GLUT1
GLUT2
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GLICEMIA 100 mg/100 ml
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GLUCOSIOin cellula
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G-6-P
Destino del glucosio 6P
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GLICOLISI
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GLICOLISI
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GLICOLISI (I stage)
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GLICOLISI (I stage)
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Glicolisi -2 stage-
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Glicolisi -3 stage-
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Glicolisi -3 stage-
GLICERALDEIDE 3 FOSFATO DEIDROGENASI
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Glicolisi -3 stage-
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Glicolisi -3 stage-
FOSFOGLICERATO MUTASI
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Glicolisi -3 stage-
ENOLASI
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Glicolisi -3 stage-
PIRUVATO CHINASI
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∆G =-17.2 Kcal /mol
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GLICOLISI
• SEDE CITOPLASMATICA
• GLUCOSIO 2 PIRUVATO
• RESA netta : 2 NADH2 ATP
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AEROBIA
ANAEROBIA
GLICOLISI