妊婦の喫煙並びに家庭内喫煙が 胎盤の糖・アミノ酸・脂肪酸 ...5-1553-i 課題名 5-1553 妊婦の喫煙並びに家庭内喫煙が胎盤の糖・アミノ酸・脂肪酸輸送に与える影響の
生物化學(II) 脂肪酸合成
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Transcript of 生物化學(II) 脂肪酸合成
(II)
1907 2 1930 1940 3 A (malonyl-CoA)
A
A A A
A
A A A A (acetyl CoA carboxylase) A (biotin) ATP
7
A (fatty acid synthase) A A A (acetyl-CoA transacylase) A (malonylCoA transacylase) (acyl carrier protein; ACP)
(fatty acid synthase)
(acyl carrier protein; ACP)
7
ACP 3- -ACP (3ketoacyl-CoA synthase) -SH 3- ACP(3-ketoacyl-ACP) CO2
7
4 6 3- ACP (3-ketoacyl-ACP-reductase) 3- -ACP- (3-hydroxyacylACP dehydrase) 2,3- ACP (2,3-transenoyl-ACP-drhydrase)
7
(palmitoyl thioesterase) 16 A A (CoASH) ACP
7
16 (4-7 ) ACP
9 9 12 15 A (fattyacyl-CoA desaturase) (Stearic acid; 18:0) (Oleic acid; 18:19)
(essential fatty acid)
(linoleate 18:29 12 ) (linolenate 18:3 9 12 15 ) (spinolipida)
- A -
A A A A I