Circle No. 138 on Readers' Service Card

Sacl Nhel Clal BspMI Bgl 11 Xhol BstElI Spel Bcl Ncol P*tlHpa SspI Nsi Sph Sal Pvu 11 IBspM 11 SnaBI Xba BstXV Kpn

Illnd 11 II IBamH

Hindll Eco

Bal BspM 11EcoRI FspI

I I

BstE 11NcoI

BspMHind III,",

BgIlI BallEcoR V Apa lI Xmnl BamHI

EcoR

IISac BspM Fsp Hpa Spe

Sal SnaB Kpn BstX Nsi lI

I ~~~~~~I II

Nhe

*ag,, ,,. 1. I.L~~ ~~~~~~~~~~~__

BstE 11IXbaIBamHlI

'Hind III Hind Ill

_ ~~~~LI

BclEcoRI

BamHXmn l

BstXApal

BspM IHind III

PSac

,t EcoR V PfIM Bgl 'PstPst Pst Pst Nhe

I III

Genes also available:1-4- _1 .1,;- I eV 1V

Genes available soon:+%r-1i ELirn A MTF R (n, t)rinterie u-lKini I.x irierTeront -i IYLeI le rXii I It '"4 '-"-'IClL

Interieukin 10 1 unter leruki 1 A(nat) l:l I,| v >Interleukin 115 Epidermal Growth Factor Interleukin Interleukirir1uIn(natInterleukin Insulin-like Growth Interferon ,BTNF ~ Factor 2 M-CSFTNFO3 TNF (nat)

BBLs range of genes is constantly expanding. Please contact us for further Briti -tchnology Limiteddetails of our new products and custom synthesis service.

British Bio-technology Ltd, Brook House. Watlington Road, Cowley, Oxford OX4 5LY Telephone (0865) 718817. Fa 65) 717598. Telex 838083 BIOTEC G.

Circle No. 192 on Readers' Service Card

-IELLM

TlqThereare nobetter

Ask for ourliterature

on Cells,Filters, and

Optics. AlsoUVTand

Laser LightSources.

For over 20 year

LLtomorrow's designs todayHellma Cells Inc.Box 544, Borough Hall StationJamaica, New York 1 1424

Telephone (718) 544-9534

International Symposiumon ImmunotoxinsJune 9-11, 1988

Sheraton University CenterDurham, NC

Session 1 Toxin Structure/FunctionJohn Collier, Jon Robertus, Sjur Olsnes

Session 2 Toxin Selection/ModificationRichard Youle, Ira Pastan

Session 3 Llgands - MABS/AlternateMichael Bjorn, Vic Raso

Session 4 EnhancersEllen Vitetta, Pierre Casellas

Session 5 Cell BiologyVictor Goldmacher, David Neville, Jr.

Session 6 In Vivo StudiesJohn Lambert, C. Scott, Philip Thorpe

Session 7 Clinical TrialsEric Groves, Dan Vallera, Guy Laurent, Lynn Spitler

Abstracts are being accepted for 10-minute talks during eachsession. Abstract should be typewritten on white paper notexceeding 8-1/2x 11 including heading, authors, institute andaddress. Deadline for submission of abstract is March 1, 1988.General Information (registration form, abstract,...)

Rosemary Bornesdo Dr. Arthur FrankelDuke University Medical CenterBox 3898Durham, NC 27710(919) 684-5621

N1o

II

FlpaCla

Hind IIIu_I

PstSty

NdeEcoR I

,

FspBamH I

EcoR1r "

I

II

Symposium Scrics, 344. Based on a symposium, NewYork, April 1986.Methods for the Diagnosi of Bacteral Diaml

of Plants. R. A. Lelliot and D. E. Stead. Published forthe British Society for Plant Pathology by BlackwcliScicntific, Palo Alto, CA, 1987. viii, 216 pp., illus.Paper, $26. Methods in Plant Pathology, vol. 2.Mfethods of Hybrkdoma Formation. Aric H. Bartal

and Yashar Hirshaut. Humana, Clifton, NJ, 1987. xxvi,480 pp., illus. $69.50. Contemporary Biomedicine.MINd HypwetnsIon. Is There Pressure to Trcat? W. E.Miall and Gillian Greenberg for the Medical ResearchCouncil's Working Party on Mild to Moderate Hyper-tension. Cambridge Umversity Press, New York, 1987.xviii, 222 pp., illus. $39.50.The olicular Basis of Viral Replication. R Perez

Bcrcoff, Ed. Plcnum, New York, 1987. xxiv, 579 pp.,illus. $97.50. NATO Advanced Study Institute Series A.vol. 136. From a school, Maratea, Italy, Aug.-Scpt.1986.Mlolcular Evolution of Life. Herrick Baltscheffsky,

Hans Jornvall, and Rudolf Rigkler, Eds. Published for theRoyal Swedish Academy of Sciences by CambridgcUniversity Press, New York, 1987. 375 pp., illus.$69.50. Cbemca Sc-a, vol. 26B (1986). From a con-ference, Lidingo, Sweden, Sept. 1985.Nonlinear ParabolI Equations. Qualitative Prop-

crtics of Solutions. L. Boccardo and A. Tesei, Ed.Longman Scientific, Harlow, U.K., and Wiley, NewYork, 1987. viii, 232 pp., illus. Paper, $49.95. PitmanResearch Notes in Mathematics, 149. From aconfer-ence, Rome, Italy, April 1985.Non-Oxide Technkal and Enginleeng Cwamcs.

Stuart Hampshire, Ed. Elsevier Applied Science, NewYork, 1986. xiv, 458 pp., illus. $95.75. From a confer-ence, Limerick, Ircland, July 1985.

Nutrition of Humans and Selcd Animal Spe-ces. Milton L. Scoet. Wiley-Interscience, New York,1986. vi, 537 pp., illus. $69.96. Intended for studentsand readers lacing a scientific background.Ordeed Media In Chemical Separtons. Willie L.

Hinze and Daniel W.Ar n, Eds. American Chemi-cal Society, Washington, DC, 1987. x, 293 pp., illus.$54.95. ACS Symposium Scries, 342. Based on a sympo-sium, New York, April 1986.P enicity and Clinkal Slgnfilcanc of Coagu-

lass-Netive Sbtphylococcl. Gerhard Pulver, PaulG. Quie, and Georg Pcters, Eds. Fischer, New York,1987 (distributor, V;CH, Deerfidd Beach, FL). xii, 290pp., illus. $95. ZentnalblftrB i, MMikrobiokoeund Hyiee, supplement 16. From a smposium, Hep-penheim, F.R.G., June 1986.Phosphabt Meitbolsm and Cellular Regulation

In Microorganisms. Annamaria Torriani-Gorini et at.,Eds. American Socicty for Microbiology, WashintonDC, 1987. xii, 316 pp., illus. $49; to ASM memnbrs,$39. From a symposium, Concameau, France, 1986.The Physics of Phas Spac. Nonlinear Dynamics

and Chaos, Geometric Quantization, and Wigner Func-tion. Y. S. Kim and W. W. Zachary, Eds. Springer-Vcrlag, New York, 1987. x, 449 pp., illus. $45.70.Lecture Notes in Physics, 278. From a conference,College Park, MD, May 1986.

Psychiatry and the Cinema. Krin Gabbard andGlen 0. Gabbard. University ofChicago Press, Chicago,IL, 1987. xx, 304 pp., illus. $24.95. exaiinaton ofpsychiatrists as represented in films.

PsycologicalEvalutDon of eDelopntal-ly and Physically Disabled. Vincent B. Van Hasseltand Michel Hersen, Eds. Plenum, New York, 1987. xiv,334 pp. $45.Quantitative Ecological Theory. An Introduction

to Basic Models. Michael R. Rose. Johns HopkinsUniversity Press, Baltimore, MD, 1987. viii, 203 pp.,illus. $25.Slected Readings In Mineral Economics. F. J.

Anderson, Ed. Pergamon, Elnsford, NY, 1987. x, 399pp., illus. $45. Sponsored by the Canadian Institute ofMining and Metallurgy.The Soviet Perspective on the Strgic Defense

Intihive. Dimitry Mikhcyv. Pergamon-BraseMcLean, VA, 1987 (distributor, Perpmon, Elmsford,NY). xii, 95 pp. Paper, $9.95. Institute for ForeignPolicy AnalysisPForeign Policy Rcport.Studls of Organic Molwcus. Joel F. Licbman and

Arthur Greenberg, Eds. VCH, Ncw York, 1986. xiv,385 pp., ilus. $77.50. Molecular Structure and Energet-ics, vol 3.World Gold Deposits. A Goologcal Classification. J.

J. Bache. Elswvier, New York, 1987. xx, 178 pp., i1us.$45. Translated ftom the French edition (1982) by J.Wanklyn.

PersonnelPlacement

SCIENCE publishes each Friday, except the last Fridayof the year. Advertising is accepted only in writing; noabbreviations. Any deadline in ad must be at least 2weeks after date of issue in which ad appears. Also,personnel advertising is accepted only with the under-standing that the advertiser does not discriminateamong applicants on the basis of race, sex, religion,age, color, national origin, handicap, or sexual prefer-ence.

UNE CLASSIFIED ADVERTISING DEADUNES:Thursday, 10 a.m., 2 weeks prior to issue date (mailedon issue date).

POSITNs WANTED: 40¢ per word, plus $4 for use ofbox number, per week. $10 minimum, per week.Prepayment required. This rate is available only toindividuals seeking jobs.

LINE CLASSIFIED (POSITIONS OPEN, COURSES,FELLOWSHIPS, MARKETPLACE, and so forth):$38.00 per line; $380 minimum, per week (minimumcharge covers one inch on a single column; one inchequals 10 lines of 52 characters and spaces per line).No charge for use of box number. No agency cornmis-sion for ads less than 4 inches. No cash discount.Prepayment required for all foreign ads. Purchaseorders and/or cover letter including billing addressrequired for all other advertising.

To ESTIMATE ad coet:Structure ad copy on a separate page, on lines of 52characters and spaces. Include any desired heading.Each line of heading, and/or extra line spaces, and allpartial lines (including centered reply information) arecounted as full lines. Ad titles located within the textare printed in boldface caps and are only 32 charac-ters per line. In ESTIMATING the cost, multiply totallines x $38.00 = approximate cost of ad. (This is anapproximate cost ONLY: Allow for variation betweenestimated lines and actual typeset lines and the result-ing finai cost. Purchase orders must allow for somedegree of flexibility and/or adjustment.)

CANCELLATION POUCY:NOTE: Ad cancellations made after Thursday, TWOweeks prior to issue date incur a 10% productioncharge. Final deadline for cancellations is 12 p.m.Tuesday, ONE week prior to issue date. Cancellationsmust be in writing.

Send copy for all PosItIons Wanted ads and UneClassledads less than 1/6 page in size (39 lines) to:

SCIENCE Clas_Uied Advertising1333 H StreeK NW, Rom 940

WashIngton, DC 20005Telepo: 202-326455

Send copy for Fraonal Dsply ads, 1/6 page andlarger, and all Marletplace ads to:

Sch o c Inc.Ne York YL0

Telephone: 212-730-1050Blind ad replies should be addressed as follows:

Box gve number)SCIENCE

1333 H Stret, NWWahInton, DC 20005

POSITIONS WANTED

Clinical Research ocatM S. Seven years ofexpe-rience in medical resarch and Phase IH-Mph -cal dinical trials. Experienne in clinical tnals medlo-gy and administ clinical data collection and dataprocessing. Skdlls indude satisucs and SAS program-ming. Box 184, SCIENCE.

Gross Anatmy. Ph.D., experience in teaching gross,seeks research/taching position. Box 183, SCINCE.

M.S. in Biokly. Experience in plant and human tissueculture, genciic toxicology, immunohismocheist andmolecular biology, widc variety of analytcal tques.Language skills. Prefer San Diego area. Monik Clausen,Hochh6dcr Wcg 29, 29 Oldeburg, F.RG.

Physioblgst, M.D. Reach experience in nephrophys-iology (hanodynaics, endocrinology). Clinical cxpc-ncenm general internal medicine. Teaching expericnce inmedical physiology. Box 188, SCIENCE.

II DECEMBER 1987

ANALYTICAL CHEMSTPHARMACEUTICAL ANALYSIS

MANAGERBoehringer Ingelheim Animal Health, Inc., a leading

researcher, producer and supplier ofanimal healh pro-ucts, currently has an openng for a Manager in theAnalytical R&D Section oftheTharmaceutical Develop-ment Department. The qualified applicant will possess aPh.D. in analytical chemistry or equivaknt technicaltraming and experience. A minimum of3 years ofbenchlevel xperience, and 1 year of managial cxpricnce isrequired. Excellent compensation package offered. Salarycomm te with education and expericnce. Pkasesend confidential r6sum= with requirements to:

Director of Human RsrCesB~ nAnimHeat, Inc.

P.O. Box 999St. Joseph,MO 64502

Equal Oppotuty Enqiyer.

ASSISTANT PROFESSOR-Ihe Biology Depart-ment invtes applications for a tenure-tmck position inplant ecology effective 1 July 1988. Teaching responsibil-ities includc quantitative ecology, botany, participationin the depa et's core curriculum and involvement inthe College general curriculum. Expertse in biostatis-tics and cofnputer scince is very desirable. An on-gomgresearch progam that is amenabk to majors is essentialApplicants must have the Ph.D. degree conferred by thestarting date. Applications contanirng curriculum vitae,statements of teaching and scholarshlp goals and threeletters of recommendation should be sent by 15 January1988 to: Dr. Valerie M. Kish, Biolo Department,Hobart and William Smith Clleges, Geneva, NY14456.An Equa OppoAunitytAffirmatieAcuton Employr.

ASSISTANT PROFESSORNORTHEASTERN UNIVERSITY

Thle Derent of Biology at Northeastern Universi-ty invites applications and nominaions for an anticipatedtenure-track position at the assistant professor leveL. Thedepartment is seeking strong candidates with interests invirolgy, i i y, the molecular biology of cu-kryots, eukarotic biology, or areas of genetics.Candidates must have an carned doctorate and postdoc-toel experience, and must demonstrate a high potentialfor success in research and tachding. Each applicantshould send curriculum vitae, and albrief statement ofresearch plans, and arrangc to have at least threcleters ofreferenc sent to: Sear Committee, Derment ofBiokly, Northeaster Unirsity, 360 Hun onAvenue, Boston, MA 02115. N east is EqulOpportunityLAffirmasivActio, Tt IXU .

ASSISTANT PROFESSOR-BIOCHEMISTRY.Tre-trackl position available August 1988. The De-partment offers the B.S. degree in biochenistry, the B.S.and MS. degrees in chemstry, and has a joint Ph.D.degree program in biomedical sciences with EasternViginia Medical School. A candidate should have anearned doctorate in biochemitry or dinical chemitrywith poctoral experience preferred. Rcsponsibilitieswill in ude teach undergraduate and graduatecourses and initiating a vigorous esearch program. Allarea ofbiochemisty will be considerd. Salary commen-surate with qualifications and experience. Send curricu-lum vitae, a brief statement of research interests, andthree letters of recommendation by 1 February 1988 to:Dr. R. L Williams, D arbtment of Chemical Sci-ences, OldDominion University, Norfol,VA23508.AnAffinnatirAcaion/mEqsul Opportnity Employer.

ASSISTANT PROFESSOR OF BIOLOGY, ten-ure-track. Ph.D. in a biological science with emphasis inplant genetics required. Prefrence given to geneticistswith broad general bacround and strong commtitentto taching with emphasis on st writi and prob-lem-solving skilLs. Dutes: teaching courses m geneticsthe Agricultral Biology program, molecularbiolgy andgeneral bioloy; scholey activity; colle services. Sendcurriculum vitae, transcipts, and three letters of refer-ence to: Dr. arles J. B , Depa tofBiobovCalioni State Collge, Ba d, CA 93311. Ap-plication dline: 1 February 1988. CSB isanAffirma-tivActin/Equal Opportunity Employer.

PERSONNEL PIACEMENT I599

(Continuedflm p*je 1593)POSITIONS OPEN

NPOSITIONS OPEN

ASSISTANT PROFESSOR Tenure-track 12-month position for Ph.D. in human and/or basic sciencenutrition. Tcaching and postdoctoral research experiencedesirable. Teach graduate courses in interdepartmentalM.S. and Ph.D. nutrition program and dev p a re-search program, inud ting etramural fiuids.Availablc 1 August 1988. Deadline 15 March, or untilpoition is filled. Submit curriculum vitae and threeDvsonof rerence to: Dr. Ruth Feelky, Director,Divion o Nutrition, Emor Unity School ofMedicine, 69 Butler Street, S.E., Atanta, GA 30303;tdlephote: 404-589-3363. Eqa OpporuityL4ffirma-tie Aton Employer.The Deparment ofBiological Sciences invites applica-

tions for a full-time tenure-track appointmnt at theASSISTANT PROFESSOR (ANIMAL VIROLO-GIST) leveL Applicants must havc a Ph.D. degree and ateast 2 years of postdoral experience. Preference willbe given to applicants who have demonstrtd researchcompetence i applying molecular approaches to thestudy of animal virology. Appcants must becapable oftahing g al virology at graduate lvel.The willbe expected to establish an independent rcesarch pro-gram that must integrate well with cxistng researchgroups. Salary is commensurate with eerience. Curic-ulum vitae and a list of rfnces (name, address,telephone) shoud be sent to: Dr. Lary P. Jones,Dep qtmenofBiologdcl Sciece, UnieriyofTex-as at El Paso, El Paso, TX 79968-0519, by 1March1988. Date ofappointment is 1 Se be 1988.M -is and women a c d t p. The Univei isan Equal Emplyment Opp nnaxt i Actio Em-ployer.

ASSISTANT PROFESSOR-The Deparm ofMolecular Pathology at the M.D. Anderson Htospital andTumor Institute is seeking to fill a tenure-track positionfor a molecular biologisiocheiist with researc inter-est in celular on / etic growth factors.An M.D. and/or Ph.D. and postdoctral experience arerequired. Intersted candidates ould send their aurricu-lum vitae, a brief desciption offitu research intests,and the names of three refences to: Ralph B. Ar'mg-haus PhD., Charman, D t of MoleularP n(Box 85), Univer of TeasCanew ter, M.D. And opt nd

T

Institute, 1515 Hooombe Boulevad, Houstn, TX77030. AnA i AioEq O E l-er. Deadline for application materials is 15 January 1988.

ASSISTANT PROFESSOR IN MICROBIOLO-GY: Thc Deparmtme of Biological Sciences invitesappLications fr an anticipated tenure-track position.Applicants must have training in molocular biology andpostdoctoral experience. The successfiul candidate willadvise M.S. and Ph.D. level studnts and develop anextramuraly funded research program in microbialphysiol Outstanding candidates in other areas ofmicrobioky are also couraged to apply. Submitr6sum6, repnnts, statement ofresarch interest and threeletters of reference by 1 February 1988, to: Chair,Microbiology Search Commite De t ofBio-logical S e, Bowling G U t,Bowfing Green, OH 43403. AJfiwative Ac quOppounity Employer.

BIOCEMISTRYUNIVERSITY OF BRITISH COLUMBIADEPARTMENT OF BIOCHEMISMY

Applications arc invited for a tenurc-track position atthe Scvec ofASSISTANT PROFESSOR tobcn July1988 or at a suitablc subsequent date. The position issubject to final budgetary approvaL Candidates shouldhave a commitment to teaching and the ability to main-tain a vigorous and creativerc progam. Applicantsmust have a Ph.D. or M.D. dcgree and at least 2 years ofpostdoctoral expericnce.Send curriculum vitae, list of publicatons, reprnts of

representative papers, a brief d7escription of future re-search interes, and the names of three referees to: Dr.PhilipD. Bragg, Department ofBiohenmistry, Facul-tyofMeidine,University of British Ch bia 2146Health Scie s Mall, Vancnver, B.C., Canada V6TiW5. Deadline for receipt of applictions: 31 January1988.In aCAonanc wit CanadianIur reuremes

prioriy will be gie to Canadtiancuzen andeanlentreidents ofCanada..

i600

ASSISTANT PROFESSOR OF BIOLOGY: Ten-ure-track; position to star fall semester 1988. Experiseand primary teaching responsibility in comparaive verte-bratc anatomy. Additional teaching responsibilities willinchlde partion in introductory biology and/orcourse in s y. A Ph.D. is required and postdocexperence IS desirable. Candidates are expected to devl-op a research program with the potential forsupport, participate actively in d ntal affirs, andcehibit a personal concem for students. Applicantsshould send official transcipts of undegraduate andgraduate work, curriculum vitae, a brief statement ofresearch and teaching goals, and at kast dtree letters ofrecommendation. To cnsure consideration ofyour appli-cation it should bc rceived by 8 Fcbniary 1988. Thesearch will continue until the positon is filled. Materialsshould bc submitted to: Dr. Josph A. J. Orkwis-zewsk Chair, Deatmt of Blogy, VilnovaUniversity, Villao, PA 19085. Vasnom Unerityus an Apmatve Action/Eql Educationa Op tnxityInstirm. Women and minorties ar aspecayto agy.

ASSISTANT PROFESSOR (SENIOR RE-SEARCHER): The succsful applicant will initially beresponaible for analvzi,r ipt and modelingmeauremets obuied dunng recent uppe occan cx-penments. This is a 2-year fi'-tem appointment (pos-sible reewal for a third year). Qualifications: Ph.D. inphysical oceanography, physics or gerin ; lto 3years of p olexperience; demonstatomresearchcapability; strong backWround in fluid dynamics; interestin upper ocean dynamics. Salary: $26,000 to $34,000,depending on qualifications. Rksum with names, ad-dresses, teephone numbers of three references must bereceived by 28 Februaq 1988. Send to Do R.CaIdwell, Dean, Co!clle of y, CODE -005, Oregon State Univeriy, Corvallis, OR 97331.Or onSta U A Atiox/Eq Op-poEn,yE aosw 504, Reh.bILAct of 1973. Oryon State Urt b apo&y ofbeyrpnsetothe ne Ofda-aerculs

ASSISTANT PROFESSOR POSMONSDUKE UNIVERSITY MIEDICAL CENTER

SECTIION OF CELL GROWTH,REGULATION, AND ONCOGENESIS

DUKE COMPREHENSIVE CANCER CENTERDuke University Comprehensive Cancer Center in-

vites plions for tenure- positons in a newlycreted on ofCeGrCowth, Regulation, and Onco-genesis at the level ofassisant professor. Investgatorsworking in any area ofcancer bioloy are enouagd toapplr, but special considrati wi b given to thoscwork i thc areas of growth and ditiatio fac-tors, signal nsducto, genc rgulati oncog,moiccuar aspects of tr on and drug resistnce.Applicants vith postdoctoral experience should haved strated high ei for _ subsuntialindependent rea. Succesl candidates will also beappointed into a basic science deartment within theMedical Center.

Applicant should send currkulum vitae, a brief de-scnptmon of present and proposed research, and thenames of several refrences to: Dr. Robert ML Bll,Cairman, Search C of ClG_ ao d ogn, Duke Com-

e ae. Cener, Box 3814, Durham, NC17710.To be assured offuliconsideration, applications should

bc received by28 February 1988.Duke Uns ay a an Equal OppoGutyLAfix e

Aation Employer.ASSISTANT PROFESSORS. Applications are in-

vited from outding cdates for tenure-trac posi-tions with training n Cell physiology or regulatorybiology. Wc are partic insted in viduals whoplan to develop an independent esearch prgram involv-ing neurobiology, angigen or gowth factors, butoutsanding candidates in other fields will definitely beconsidered. Applicants should submit curriculum vita,description of futre research progran, and have threeletters of ence sent to: Dr. James T. Stuall, Chair-man Department of Ph lo The U t ofTc Sowe M icl nml at Dala, 5323Harry Hines Boulev , Dalas, TX 75235-90 (for-mely The Unverty of Texas Healh Scen Canenr atDallas).AnAjnaewAction/EquaA Opp qiy Exnor.

ASSISTANT PROFESSOR, MEDICAL ON-COLOGY-University of Colorado-Tenure-track inMcdicine. Candidate expected to esublish independentlyfimded basic research in cancer biology. Compktion ofMedical Oncoogy Boards, U.S. medical license, 2 yearsof postdoctoral basic research required. Start-up Endsavailable. Salary $40,000 to $60,000. Scnd curriculumvitae and throe re nce leters to: Dr. L MchadelGbode, Univerity of Coloado Hcalth Siences Cen-ter, 4200 East 9th Avenue, Denvcr, CO 80262;telphone: 303-270-8801. An Equal Oppo0tity Em-pk~yer

ASSISTANT PROFESSOR, PHYSIOLOGYAvailable fail 1988. Ph.D. required. Teach gencral

physiology, mammal physiology, and/or ccll physiolo-gy; direct graduate students; maintain acive researchprogram; demonstre ability to secure extramural fund-ing. Curriculum vitae, statement of rcsearch goals, andtree letters of must be received by 15February 1988. Send to: Dr. Gary W. Childers, SearchCommittee Chaiman,D t of Biolgial Sci-wens, Box 814, Sohe e Lis Uniersity,Hammond, LA 70402.AnEqual Oppmunisy Emplyer.The Deparmt of Biology, College of St. Thomas,

invites aplications for TWOfull-time, tenure-track po-sitions at the ASSISTANT PROFESSOR level:

(i) BEHAVIORAL ECOLOGIST, to teach ad-vanced courses in animal behavior and behavioral ecolo-gy, and an introductory course in ecology, adaptation,and diversity.

(ii) CELLULARIMOLECULAR BIOLOGIST,to teach advanced courses in cell biolgy and molecularbiology, and to partcipate in teaching an introductorycourse in this same area.

Bothjpositions also carry an expctaton for develop-cnt ota vigorous research program invohling under-

graduate studets.The College ofSt. Thomas is a co onal Catholic

liberal arts college committed to the total development ofthe individual student. The essfil applicant will havea Ph.D. and a strong commitment to both teaching andrescarch at the underauate levd Send letter of appli-cation, curriculumvitae, descriptionofrsc plan, anddtree letters ofrcfcrence to: Mrs. yFeHl, Bax4208,Collegc of St. Thomas, 2115 Summit Avenue, St.Paul,MN 55105. All mateials must be received by 15January 1988. An Equad Oppotwnity/Affinnate AainEmployer.

ASSISTANT PROFESSORS-MOLECULARBIOLOGY. Two tenure-track positions (req re-search and hing) are available in an pd -partment for fall 1i88. Resarch areas of special interestare: mollar biology of genc Cxpression mnedwith plant or microbial systems, viroloy, or immugy, or protein ennering. Submit quiries, curriculumvitae, statement of interests and three ktte of referencepreferablyby15 January 1988 to: Dr. WayneE. MaeHead, Department ofBiocinc sad B-iotechnology,118 Stratton Hall, Drcxd Univ y, Phiadephia,PA 19104. Drd Univriy is an Afm e Aio/Equal Op tnxity Empyerand eiw apa-tiomfium wmen and menonues.

ASSISTANT/ASSOCIATE PROFESSOROF BIOCHEMLISRY

UNIVERSITY OF ILLINOISAT CHICAGO

COLLEGE OF MEDICINEThe Depamnt of Biological Chemistry is seeking

applications for a tenure-track ps-sor position effective academic year 1988 or later in thearea ofmolcular biology of ryotic gene expression.The Department is strong in this area and is commto further expansion. We are seeking candidate with astrong commitment to devloping an inde re-search program and teaching in a lar medical schoolenvironment. Applicants should provide curriculum vi-tae, at least three letters ofrernce and a statemect ofresearch interests and plans by 1 March 1988. Scndapplications to: Dr. ICbert Stord, De t ofBio cal Chemitry, Univerity of Illinois at Chica-go, C e of Medie, 1853 West Polk Strect,

IL 60612.ThebUnicersIfinois at ChG*o is an AffnirativeAcEqalO n Enlor.

SCIENCE, VOL. 238

POSITIONS OPEN POSITIONS OPEN

POSITIONS OPEN

ASSISTANT/ASSOCIATE PROFESSORPROTEIN BIOPHYSICAL CHEMIST

The Department of PharmaceuticalCh (Phar-maceutics) at The University of Kansas invites applica-tions for a tenure-track position starting in August 1988.Applicants should be experment-oriented chemists orbiochemists who can applyimodem h icochemicaltoecniques to study proteins especially of pharmaceuticalintrest.

Applicants are ecxpeted to possess a Ph.D. degree inphamiaceutics, biochemisty, che ,or a related area.

will be given to applicants with educationalbackground or research expenence in the pharmaceuticalsciences. Applicants should have a demonstrated abilityto communicate eflictively, an interest in tcaching, andhave shown acceptional research capability/potential.The faculty member will have teaching responsibilities atthe undergraduate and graduate levels and will bc expect-ed to develop a strong pendent research progrm.

Applications should indude curriculum v, lttersfrom three refrences, and a short statement of futureresearch interests. Scnd applications by 4 January 1988to:

Dr. Ronald T. BorchardtDepartment of Pharmaceuticala Chemisty

3006 Malott Hall

L-wrne, IS 6605The Unireity of Kamas is an Equl Opportuni0yl

AffirmativetAaim Employr.

MEDICAL COLLEGE OF GEORGIAThe Department of Physiology and Endoainology

invites applications for a tenure-track position at theASSOCIATE PROFESSOR level. Applicants shouldhave the capability of teaching and coordinating anintroductory interdepanrmetal neuroscience medicalcourse, developing graduate level courses, and a stongresearch program. Potential for interation with a pro-gram focus on cellular aspects of cardiovascular andmusdce physiology is desirable. Salary will be commensu-rate wit expence. Submit curriculum vitae, fivc recentpapers, and the names of three rerences to: Dr.Keith Green, Chairman, Physioloy and Endinolog Faculty Search Committ Dpartmnt ofOph-thalmology, MCG Box 3059, Mdical Collge ofGeorgia, GA 30912. Equa OpporsuisylAffir-

vA Employr.

ASSOCIATE VICE PRESIDENTFOR RESEARCH AND

DEAN OF THE GRADUATE SCHOOLThe University ofNevada-Reno (UNR) imits nomi-

nations and applications for the position Associate VicePresident for R:esearch and Dean ofthe Graduate Sciool.

Primary responsibilities include: deveopment ofUNR's research capabilitics, espeially in the acquisitionofextcmal grants and contracts; development ofrescahsupport services; and administation of resarch pro-grams and the Graduate School.

Qualifications includc: an carned doctoratc; tenurableas a professor in a university dartmnt; possess adistnguished personal record acadeic rsarch andgraduate education; interpersonal skills; and a demon-strable knowledge of extnal fiuding agencies.

Salary is negotiablc commcnsuratc with qualificationsand cxpericnce. Deadlinc for receipt of applications is 15January 1988 or until the position is filled. To applyplease send a ltter of interest, curriculum vitac, andnames, addresses and telephone numbers of fivc refcr-ences to: Dean Jon Epps, Chair, Associate Vice Presi-dent and Graduate Dean Search Committee Office ofAcademic Affairs, Universi ofNevadl-Reno, Reno,NV 89557. Teleone: 702-7845-1740. An EqualEmploymen OpponitAffinnatw Action Institui.UNR on U.S. citsens and alens lfid autho-

o*in teU.S.

BIOENGINEER, Ph.D. with a baound in lasersor arteriosclotic disease; prefer grant experence. Facul-qy appointment and salary dependent upon qualifica-ieons. Must have publications. Startig date: July 1988.Please contact: Tero Mataumoto, LD., Ph.D., Pro-fiesor and Chirman, Department o£f Surgry, M.S.413, Broad and Vine Streets, Philadlphia, PA19102.

II DECEMBER I987

T CELL SCIENCES, INC., an emerg-ing health care company engaged inthe development and marketing oftherapeutic and diagnostic products,invites applications for the followingposition:Em munolo ist

Ph.D. or M.D. with expertise in cyto-kine research, monoclonal antibodyproduction and cell mediated immun-ity preferred. Experience in industryand supervision highly desirable.Positions at T Cell Sciences include acareer enhancing environment andoffer the opportunity to interface withinternationally recognized scientists inconverting their discoveries intoproducts.We're an equal opportunity employer,offering comprehensive medicalldental plans and competitive sal-aries. Please send your resume to:Paula R. Freeman, T Cell Sciences,Inc., 840 Memorial Drive, Cambridge,MA 02139.

rT CELL___SCIENCES

__ _ Now

Protein Crystallography and ComputationSeveral PhD level Visiting Research Scientist positions areavailable within the Protein Crystallography group of Du Pont's Cen-tral Research and Development Department. Successful candidates willhave research experience in protein x-ray crystallography and/ormolecular dynamics simulations. State-of-the-art facilities are availablefor protein purification, automated crystallization, data collection, com-putation and interactive graphics. These one-to-two year temporarypositions require proficiency in protein isolation, crystallization andstructure determination, or experience with modem computational andgraphic techniques for studying protein structure.

At the world renowned Du Pont company you'll find astimulating scientific environment in amodem research facility locatednear Wilmmigton, DE. Du Pont provides competitive compensation andrelocation benefits. Our Mid-Atlantic location offers a wide range ofacademic, cultural and recreational activities. Interested candidatesshould send their resumes and references to Dr. F. Ray Salemme, c/oEmployee Relations Department, Room X50958, Wilmington, DE 19898.

U.S. Citizenship or Permanent Visa RequiredAn Equal Opportunity Employer M/I/H/V

,UusaO-N

PMRMACEUTICAL CORPORATION

CELL BIOLOGIST/PHARMACOLOGIST

Nova Pharmaceutical Corporation, aleading research and developmentcompany in Baltimore, MD, is invitingapplications for a sdentist with exper-tise in growth factors and cytokines toparticipate in a unique drug discoveryprogam. The successful candidateshould possess a PhD and 0-4 years ofpostdoctoral experience. Individualswith training in pharmacology, bio-chemistry, molecular biology, immu-nology or cell biology are encouragedto apply. Those applicants, however,with a demonstrated understanding ofligand-receptor binding and cell cultureare preferred. The position will requiresupervision of a small group of techni-cal associates, plus excellent writtenand oral communications skills.Nova Pharmaceutical Corporation of-fers an excellent compensation andbenefits package as well as a challeng-ing work environment. Interested indi-viduals should forward their resume,along with a cover letter detailing spe-cific interests and three references to:L. Faris, Nova PharmaceuticalCorporation, 6200 Freeport Centre*CB/P-PK, Baltimore, MD 21224.

Rngmg --------------

POSITIONS OPEN

ASSISTANT OR ASSOCIATEPROFESSOR OF BIOLOGY

Tenure-track position, September 1988; doctorate andteaching cxpericnce required; undergraduate teaching inenbryology, histology, and inertebrate zoology. Salaryimpeitive and may be cnhanced by as much as 50%

tbrou~h a Bingham Award for Excellence in Teaching.Submit curnculum vitae and three letters ofreference to:Dr. J. Hill Hamon, Program inBig, T slvaiaUniVrSity, KIhIKY 40508. Tlvaia naEquW netBEHAVIORAL NEUROSCIENTIST-Thc De

parmtentofPsycholwgy, Duke Univcrsity imnites applica-tions for a visiting asssant professor (nontenure tack)for a period of up t 4 years. We seek an individualworking at the interface of brain and behavior. Specificapproaches and methodologies are not as important asthe potential for research productivity- howevcr, a devcl-opmcntal perspective would integrate well with existingresearch programs in the Deparmlent. Teaching at boththe graduatc and underrraduate lcvels is cxpected. Appli-cants with postdocor cxperience are prefrrendcurriculum vitae, reprints, statement of research plansand thrc letters of reference to: Behavioral Neci-ence Search, Department of PsycholgyX, Duke Uni-versity, Durham, NC 27706, by 1 February 1988.Duke Unirety isanAffirmatv AaonoEqxal OppotuntyEmpoyr.

BIOANALYTICAL FACULTY POSMON. ThcSchool of Chemistry, Georgia Institute of Technolgy,mvites applications for a tenure-track faculty poston mbioanaytical chemistry strting 1 September'i988. Theeosition will be at the levl ofassistantprofessor, and willpornpart of a continuing exansion in the areas ofanalyical chemisty and biochemistry. Candidaes fromall developing areas at the interface between analyticaland biochemistry are invited to apply, especially thosewith interests in analyfical aspects of bhi:oimmunochmistry, enzymology, oiiarmay,bolo-chemical spectoscopy, and mcmbrane roceptors. Candi-dates will be expectd to establish a dynamic rescarchpro~ram. Closing date for applications is 15 JanuaryI98, but ear plication is encouraged. Candidatesshould apply to: R A Pierotti, Director,School o Georia Institute of Tedunolo-gy, Adanta, GA 3332-040, enclosing curriculumvitae, Xerox copies ofund uate and graduate tran-scripts, and an oudin of sarch plans. Candidatesshould also arrange for three letters of recommendationto be sent. Georgia Techiwan Equl OppnuniyMlna-tnmAcion Employer.BIOMEDICAL NMR POSTDOCTORAL POSI-

TION available imduniately. The Univcrsity of Ken-tackQy Magnetic Resonance Imagn and SpectroscopyCenter is seeking a Ph.D. with experience in in vivoNMR spectroscopy and/or magnetic resonance imaging.Training in areas such as bioche , physiology orpharmacology is desirable. The successful candidate willparicipate in a variety of expimnts being performedon our 4.7T 33-cm multinuclear imaging/spectroscopysystem and high field NMR spetts. A ltter ofintent, curriculum vitae, and three letters of recommen-dation should be sent to: Dr. Stanford L S*MRISC, 101 Slone Building University of K-uky,LI n, Y 405 0053 by 1 January1988. The Unevena ofKetucky is n Eql O tEmployer.

CELL BIOLOGISTThe Department of Biology at St. Olaf Colkge is

seeking a cell biologist for a tenure-track position at theassistant professor level to begin late August 1988.Teaching responsibilities will indude an upper-kvelcourseincel biology with a laboratory and an introduc-tory co cl or cs.Applicants in anyarea of cr biology or ceUld will be c .The successful candidate wbe cxpected to develop anactive research program in cell biology or physiologyinvolving undgraduate students.

St. Olaf is a coeducational liberal arts colleg of theEvangelical Lutheran Church of America. Qualified ap-plicants should submit curriculum vitac, transcipts, adescription of andtea g interests and goals,and three letters of reference by30lanuaby 1988 to: Dr.Ted R Johnson, Chair, Biology Dnepatment, St OlafCollege, Northfied, MN 55057. St. OlafColge ranEqsl Opponwity Employer.

I6o2

The Department of Biology at the University of SanDiego (USD) is seeking a BOTANIST to fill a tenure-track position at the assisant or associate professor levelbeginning 1September 1988. Wc are seeokng a candidatewith a broad background in the anatomy, physiology,and ecology of vascular plants. Tcaching responsibilitiesinclude participation in mtoductory biolgy and devel-opment of an upper division course in botany.USD is a Catholic university whosc primary aim is

teaching excellence. Active scholarship by the facuky isconsidered essential to this aim. The candidate expect-ed to maintain an active research prgram which has thepotential for undergraduatc involvement. Teaching expce-rience is desirable. Women arepatuLy toap. Aplication materials consisting of curriculmvitac, a dcscipton of teaching philosophy and resarchinterests, and names and addrsss of thre profesionalre*frences must bc received before 15 Fcbruary 1988.Address all correspondnce to:

Dr. Louis E. BurnettChair, SearchDeSarment of BilogyUmrsy of SaDig

Alel Par

Sa Dieg, CA 92110

CHAIR, DEPARTMENT OF GEOLOGYUNIVERSrrY OF NEBRASKA-LINCOLN

(SEARCH RE-OPENED)Applications and nominations are invited for the posi-

tionofC hairp n ofthe Department ofGeology oftheUniversity ofNebraskaLincoln. Appointment will be atthe full professor levl; salary is open and wil reflect

x and qualifications. A Ph.D. is rquired.Responsibilities include ladership of the nt

and maintenance of strong tiaes= the State Museum,Statc Goolorical Survey, alumni, industry and govern-ment aVencies. Applicants should have develoed an

research prog am,

using quantitative approaches. A record of success wishfunding agencies is expected. The chair is also e dto teachi and to direct the work of graduate students.The deparmt has 13 faculty; qualified stafffrom the

Muscum and the Survey; also teach and direct the workofgraduate students. Th dparent has modem, newlyrenovated quartes, and cxtensive intrumentaon andcomputer capabilities. Graduate student and faculty re-ccmphasizes the integration offield and laboratoDr

studies, primaril in soft-rock geology and hydrogel-ogy-

Applicants should send curriculum vitae, list of publi-cations, a description of current and planned research, alist of courses taught, and names and address of threerefecrnces bylaF5 1986 (or until suitabk candi-dates apply dthrefter) to:

Anthony F. SuraceChair, Geology Scarch

1223 Oldfather HallUniversity of Nebraka-Linoln

Lincoln, NE 68588-0312Note: Previous candidates need not reapply since

already submitted materials will be utilized.AffimaiveAaion/Equa Opportunity Employer

DIRECTOR OF AUDIOLOGYThe Department of Otolaryngology at the University

of Minnesota is inviting appications for the posiion ofassociate proessor or profssor, depending on qualifica-tions. This a ten position. Applicants should havea Ph.D. in audiology, f science, or reated disci-pline. CCC-A is pr The succcssful candidate willdirect the acivities of the Audiology Clinic, teach medi-cal snAtents and graduate students, and conduct resarch.The last date for receipt of applications is 15 February1988. Applcants should se curriculum vitae, threekers copies of published andunpublished research work, and a bri statement ofprofessional and research interest to:

David A. Nelson, Ph.D., ProfesoChairman ofAndiolo Search Committe

Depatment of

Box 396 of Hopil and ClinicHarvard Street at East iver Rd

Minnepolis, MN 55455The Unienity o,fMinnst i an Equl Opportunity

Educator and Ecl%er, and e4y invite and encour-aes ion women an mnorte.

CHAIRMAN

GRADUATE PROGRAM INBIOENGINEERINGPENN SrATE

Nominations and applications are invited for the posi-tion of Chairman, Graduate Program Committee inBioengineering at The Pennsylvania State University.The program, which is jointly administered by theCollegc of Engineering and the Graduate School, cur-rently offers courses and has research activities in elctro-physilogy, artficial organs, medical imagiW,bioeni-neering mechanics and transport phenomena. The suc-cessful candidate must possess academic crodentials ofthehighest quality incuding an earned doctorate and anestablished repaion in a bioen0neerinn field. TheCollege seeks an individual who wli provid innovativeand nreic adership, with strong administrativequalities. ominations and letters ofapplication, accom-paniedby curriculum vitae and s winbe receivetby: The Chairman, I i Chair.m Se Comittee,233.EDg ^Office

Buins B 5, Pe Universy,Univerity Park, PA 16802, before 28 February 1988,or until the position is filled. An Equal OpAffiruatieActio Empoyff.

DEPARTMNT OF NEUROLOGYUNIVERS1TY OF CALIFORN , IRVINECLINICAL INSTRUCTOR/POSTDOCTORAL

FELLOWSHIP for M.D. and/or Ph.D. in elctrophysi-ology to record somaos y evoked potenials usingnatural stimuli. All in applicants should sendcurriculum vitae and three leters of refercnce to: Dr.Anold Starr, Professor, Department of Neurolog,Univery of Calirnia, Irine, Irvine, CA 92717.An Equal OpportunityL4ff sativAc eion Emplyer.

DEVELOPMENT ASSISTANCE POSMON.Tropical Research and Dcvelopment; has immediate

in Florida for Ph.D. professional in resource oragrculural economics, applied anduopolog, or forest-ry. Field exprience in Afica; French fluncy; excellentverbal and writing skills; project manage t experiencewith Agency r International Development. Send com-plete rfsumd to: Dr. Josh Dickinson, 4010 NewberryRoad, Suite C, Ganesile, FL 32607.

DIRECTOR OF SCIENCECONSERVATION INTERNATIONAL

Position available for a Ph.D. to direct development ofscentific products and support activities which enhancebiolgicalconservation. Supervising a dpartmtal staffof five to seven, the director manages a reional datacenter and dircts project design for work m zooogy,botany, ecology, and biogeorphy; and coordinatescosely with pioect manars at headquarters and in thefield. Plannig, personne selecton, b fund.raising, and intntutional relaions are keyresponsi-bilities. Apphicants should have a doctorate in naturalscicnces, prefrably plant ecoogy; Spanish/English fluen-cy; and rserch or conservation experience in LatinAmerica or Caribbean. Send currculum vitae and namesofth references to: GuilerW. Mann, Vice Presi-dent for Science and Stratec Pannin Coneva-

IntrNationl, Street, NW, #1002,

Washington, DC 20036.

SCIENCE, VOL. 238

CYOGIENETICIST M.DIPhD. Phsi-cian or pathologist preferred. Spocialty certifica-tion (or equivaernt training) and background inclinical diagnostic and research work important.Funded basic research frant support and evi-dence of productivity critical. Experience and arecord ofscholarship with a strong publicationrcrd are ;oquirZ. Minimum ot 2 years ofbexpence nm human cytogeneics necessary.Wonad memheefnunosygws are ecwur-aged to !y. Please forward curriculum vitae to:Jon ED. C ead, MD., Deprtment ofPa-tholgy, Univer of Vermont, Burln,VT 05405. Applications will be accepted until 1February 1988.

POSITIONS OPEN POSITIONS OPEN

Reserch Assodatesl/PostdocsPharmacological Srcinces

Genentech, Inc., a leader in the field ofbiotechnology, currently has the follow-ing openings:

Postdoctoral ScientistOur Pharmacological Sciences Depart-ment seeks an individual to participatein research projects examining the mole-cular mechanisms of the effects of cyto-kines, immunosuppressive and anti-inflammatory agents, and recombinantproteins on cell function.The successful candidate will have 1-3years' training with experience in one ormore of the following areas: cell biology,protein chemistry, or signal trans-duction. Experience in working withanimal model systems helpful.

Reearch AssociateIn this position you'll perform in vitrotesting of cytokines, immunosuppressivepeptides, and anti-inflammatory proteinsusing a variety of assay systems. In addi-tion, the position requires maintenance

of cell cultures and characterization ofprotein samples.The qualified candidate will have experi-ence with cell culture, polyacrylamidegel electrophoresis and preparation ofhuman leukocytes for in vitro testing. B.S.with 3-5 years' experience or M.S. with2 years' experience in related areasrequired.Genentech, Inc. offers an excellent sal-ary and benefits package coupled withthe opportunity to make a significantcontribution to our organization. Pleasesend resume to Sherrie G. Wilkins,Genentech, Inc., 460 Pt. San BrunoBlvd., South San Franicsco, CA 94080.An equal opportunity employer.

3 D 0hu 0} @ h90o.

Ou@anwho OQ°sI ntA Inc.

3 D oh nto

REPORTERRESEARCH NEWS

SECTION OFSCIENCE

The Research News sectionof Science has an opening fora PhD in the physical or engi-neering sciences who is inter-ested in reporting on develop-ments in these areas for themagazine. Candidates shoulddisplay an ability to write lucidand lively articles. Coveragewould include current topics inchemistry, physics, materialsscience, and engineering. Anapplication for this full-timeposition in Washington, D.C.should include a curriculumvitae, salary requirements, aletter describing your interestin Research News, and ap-propriate writing samples.Please send requested infor-mation to: C. Bell, SCIENCE,1333 H St., N.W. Washington,D.C. 20005. EOE

T ~DIAGNOSTICS|i ~~RESEARCH c| - ~SCIENTIST t

XMarion Laboratories, Inc., a leader in the rapidly expanding, hightechnology segment of the health care industry, currently has positions

available for research scientists in our DiagnosticAffairs Department within

Primary responsibilities will include isolation and purification of antigens

and antibodies, preparation of diagnostic reagents, development andvalidation of assay protocols and interaction with marketing and manu-

facturing groups.

Candidates must have a graduate degree in Immunology, Microbiology,

Biochemistry or a related science and three years of experience in

developing diagnostic products. Experience in all phases of diagnostics ..research from product development through production is desirable. ;

We offer a complete compensation and benefit package to include bonus,

stock options, profit sharing, comprehensive group health, dental and life

insurance benefits. Qualified candidates should submit a detailed resumeincluding salary history to: Recruiting & Placement, Dept. CR1, RO.

Box 9627, Kansas City, MO 64134. Equal Opportunity Employer.

g~~~~~~~~~~~~~~ ..".''.'.

XIMMarion,MaioI Laboratories,Inc. an

tecnolgy egmnPofrthehathnrindsrturnlyhspoiin

PREDOCTORALTRAINING

OPPORTUNITIES INTOXICOLOGY

are available in the College ofPharmacy and Allied HealthProfessions. B.S. and M.S.degrees in Toxicology areoffered as well as a Ph.D.in Pharmaceutical Scienceswith a subspecialization inToxicology. CompetitiveAssistantships and Fellow-ships with full tuition remissionare available for qualifiedapplicants. For more informa-tion please write to:Dr. ljaz S. Jamall,Toxicology Program,Department ofPharmaceutical Sciences,College of Pharmacy andAllied Health Professions,St. John's University,Jamaica, NY 11439.

TE EVEISITYSSi ann's

1-

As the undisputed world leader in medicaldiagnostics recognized for ground breaking testsin the detection of Hepatitis B, Rubella, GermanMeasles and most recently, AIDS, AbbottLaboratories offers one of the most stimulatingscientific ervironments ar ere. Our DiagnosticsDivision now seeks an individual to support ourproduct development efforts through the evaluationof fluidic and bio-compatible properties ofmicroporous membranes, and their compatibilitywith plastics, adhesives and environmental stress.Experience in materials science, immunochemistryand work involving poymer-protein interactionsand bio-compatibility of poyymers is preferred.With a scientific setting supported by confirmedsuperior management, Abbott offers an excellentsalary, and full benefits including profit sharing andstock retirement plans. We are headquarteredjust30 miles north of Chicago on the Lake Michiganshoreline. For confidential consideration, pleasesend your resume with salary history in confidenceto: Peggy Taylor/Corporate Placement, Dept.SCI/12-1 1. Abbott is an Affirmative ActionEmployer.

ABBOTTABBOTT PARK IL 60064"Health Care Worldwide"

- I 0

1iYa1e uNivsyEvolutionaryBiologyThe Department of Biology is engaged in buildingan interdisciplinary program in the evolutionarysciences and invites applications for positions atthe senior and junior levels. While outstandingscientists working in any area of evolution will beconsidered, areas of particular interest to our fac-ulty include molecular approaches to populationbiology or phylogeny, developmental approachesto evolution, evolution of genome organization,and quantitative approaches to evolutionary prob-lems.We seek individuals with a strong interdisciplinaryinclination, who might profit from interactionwith the Department's strong programs in molec-ular, cell, developmental, and organismal biology.Send curriculum vitae, description of research in-terests and names and addresses of at least threereferences by January 25, 1988, to:

The ChairmanDepartment of BiologyYale UnvestyPO BO 6666New Haven, Cr 06511

Yale University is an Affrmativ Action/EqualOpportunity Employer.

MOLECULARBIOLOGISTS

Merck Sharp & Dohme Research Laboratories is cur-rently offering excellent career opportunities forMolecular Biologists to join the expanding depart-ment of Cellular and Molecular Biology. Research willinclude the application of a broad spectrum of techni-ques in recombinant DNA, such as DNA/RNA prepa-ration, construction and screening of genomic andcDNA libraries, blot analysis, DNA sequence analysis,DNA vector constructions, and site-directedmutagenesis. These techniques will be applied to theisolation, analysis and expression of genes of poten-tial pharmaceutical interest.A B.S. or M.S. in Biochemistry or the equivalent withat least three years of broad and significant ex-perience in molecular biology are required.Excellent salary and benefits programs accompanythese positions at our modern research facilities inRahway, New Jersey and West Point, Pennsylvania.Please send your resume, three professionalreferences whom we may contact, salary require-ments as well as geographic preference in completeconfidence to: Manager Personnel Relations, W42-2,Merck Sharp & Dohme Research Laboratories, WestPoint, PA 19486. EEO/AANH/Employer.

BUILDING ANEW LAB?

LET THE SCIENCE FREE PRODUCTINFORMATION SERVICE PUT YOU INTOUCH WITH THE VENDORS WHOSEPRODUCTS YOU WILL NEED.

SIMPLY WRITE US A LETTER STATINGTHE SPECIFICS ABOUT YOUR PROPOSEDLAB AND WE WILL DO THE REST.

WRITE TO:

SCIENCE MAGAZINENEW LAB SERVICE DEPT.1515 BROADWAYNEW YORK, N.Y. 10036

Alk

I

J

THE UNIVERSITYOF NEW SOUTH WALES

SYDNEY/AUSTRALIA

ASSOCIATE PROFESSOR OF DRUGAND ALCOHOL STUDIES TO BE

Deputy

NATIONAL DRUG AND ALCOHOLRESEARCH CENTRE

Applications are invited for appointment to theposition of Associate Professor of Drug andAlcohol Studies to be Deputy Director for theNational Drug and Alcohol Research Centre.The Centre has been established Within theUniversity on the basis of funding providedby the Commonwealth Government throughthe State Department of Health. Its aim is toextend the knowledge base required for effec-tive treatment and rehabilitation of individualswith alcohol and drug related problems. A sec-ond national Centre has also been establishedin Perth, Western Austalia, which will undertakeresearch into the prevention of drug abuse.The Centre will be multi-disciplinary and co-operate with medical, psychology and socialscience schools at the University and withother bodies and individuals in Australia.Applicants should possess high academicqualifications, have a well established recordof research in this field and have the capacityto manage a research program.The appointment will be for five years witha possibility of renewal.Enquiries regarding the position may bedirected to Professor B.B. Heather, Director,National Drug and Alcohol Research Centre,University of New South Wales, P.O. Box 1,Kensington, N.S.W. 2033, Australia.Salary: A $49,790 per annum.Subject to consent by the University, theappointee may undertake a limited amount ofhigher consultative work.Details of the position, together with theconditions of appointment and applicationprocedure, are available from the AcademicStaff Office, P.O. Box 1, Kensington, NSWAustralia 2033.Applications close: 31 January 1988.Equality of employment opportunity is University policy.

-S.~~~~~

The Upjohn Company, a world leader in the research anddevelopment of pharmaceuticals, has several Associateposition openings in Cell Biology research.

Biology AssociateSuccessful candidate will have a BS or MS degree in CellBiology or related field to investigate endocytic pro-cesses and membrane sorting in cultured mammaliancells. Requirements include a demonstrated proficiencyin transmission electron microscopy and tissue culture.Experience with monoclonal antibodies, immuno-cytochemistry and immunofluorescence would be help-ful. Responsibilities will include a specific project, andcollaboration with other groups regarding morphologi-cal techniques.

Biochemistry AssociatePosition requires a BS or MS degree in Cell Biology orrelated field and the work involves both basic researchon protein secretion and glycosylation and appliedstudies of recombinant glycoproteins from heterologousexpression systems. Candidate must have knowledgeand experience in tissue culture and protein isolationand characterization, including state-of-the-art liquidchromatography methods. Experience in oligosac-charide analysis is desirable.

Kalamazoo is located in Southwestern Michigan midwaybetween Chicago and Detroit and offers varied culturalevents, cosmopolitan shopping and entertainment,lakes and woodlands minutes away, abundant year-round sports and recreation. Upjohn offers advance-ment opportunities, a highly competitive salarycommensurate with experience, comprehensive bene-fits and relocation assistance. For confidential consid-eration, please call from outside of Michigan toll free11800/253-8600, ext. 3-6767, (inside Michigan call col-lect 616/323-6767) to request an employment applica-tion be sent to you immediately. Please refer to positionnumber 1855-A when calling.

We are an Equal Opportunity Employer M/F.

I

POSITIONS OPEN

DEAN OF THE SCHOOL OF MEDICINEWASHINGTON UNIVERSIITY

MApplican are invited for the position ofDean oftheMediclSchool. Duties of the Dean include: allocation

of resources, Ion - financial and progam planning,direction of stu4ent aBairs, appointnent of all standingcommittees and chairmanip of the executive faculty.The individual selected as Dean will also be recommen-ed to the Chancellor ofthe University for appointment asVice Chancellor for Medical Affairs. The Vice Chancel-lors responsibilities inchlde: fund raising and publicrelations, representation of the Schools of Medicine andDental Medicine in interactions with affiliated hospitals,medical practice organixations, government and indus-try.

Candidates must have a disg hed record in clinicalmedicine or biomedical r . They must possess afirn commitment to academic excellence and a clear viewofeconomic, social and political problems facing modernacademic health centers.

Applications should indude curriculum vitae andnames of three referencs. Address correspondence to:Gerald D. Fischbach, MD., Chairman, DeprtmentofAnatomy and Ncurobiok,WasyingtonUner-sity School of Medicne, 660South Euclid Avcnue,St. Louis, MO 63110.Washton Unieity is an Equa 0pporuiy Emplyer

FACULTY POSMON, Oregon Statc University(OSU), PLANT MOLECULAR BIOLOGY: A 12-month tenure-track position at the assistant or associateprofessor level in the Departmt ofAgricuural Chem-stry. Applicants must have a Ph.D. in molecular biolgy,biochemistry, or a relatd field, and postdoctoral cxper-ence, prefcrably in molecular biology of plants, and bcprepared to devlop vigorous, innovative eernallyfunded research program applying molecular/genctictehniques to the stdy of plant functions important toagriculture and forestry an to direct graduate students.Familiarity vector transformation techniqus

of particular interest. Rescarch programs are assistedthrough affiliation with the Center for Gene Researchand Biotechnology at OSU. Submit curriculum vitae,incuding a statement of research interests, and arrangefor three letters of recommendation to be sent by I1January 1988 to: Dr. G. S. B de Chairman ofSearch mmte, Departm t of AgicuturalChemistry, Orgon State Unsversit, Corvals OR97331. OSU Affi natie A oEqalEmplyrand comps with Setion50 oftheRehai ;oAct of1973. OSUha apoli ofbreingrspnet the needsofdal-aser uplaes

I6o6

POSITIONS OPEN

EMBRYOLOGY IABORATORYPrivate infertility practice is seking a highly motivated

B.S./M.S. (biolgy, zoology) with interestecxeriencc inreproductivc physiology to be responsible for all aspectsof IVF area operation and management in a successfilultrasound-guided oocyte retriev program. Candidatcshould possess good sterile technique, experience withtissue culture media preparation, and familiarity withmicroscope optics and video/photo documcntation sys-tems as well as operation of other basic laboratoryequipment. Experience with oocyte identifcation andembryo staging (or willingness to learn) is desired. Salarycommensurate with experience. Send r6sumd and salaryhistory to: Dr. Ed Gaunt, Center fo ReproMedicine, 2034 Randolph Road, Charlotte, NC28207.

BIOMEDICAL ENGINEERING ENDOWEDCHAIROF EXC NCE is available in the Depart-ment ofBiomedicalE in te College of&i-neering, University of owa..The Chair is generously endowed together with sub-

stantil peripheral support. The candidate should pos-sess: (i) anearned doctorate in biomedical engineenng oran allied disciplinc; (ii) tangible evidence as a teacher andscholar and (iii) a national reputation in biomedicalengineering. Prefcrcnce will be given to the candidatewith a strong track rcoord in biomedical eininnovation and product development. The University ofIowa offers an environment hiighl conducive for re-search at the highest leve in both the CollegesofEngineering and Medicine. Nominations or applicationmaterials should be sent to: Y. King Liu, Professor andDirector, Center for Materials Research, DetmentofBiomeial Engine U ty ofIowa, IowaCity, IA 52242 preferably by 1 February 1988 or untilthe position is filled. Uni y of Iowa iv an EqualOpp yAtiA Eme.

ENDOWED CHAIR INNEPHROLOGICAL RESEARCH

FThcD ep of Medicine of the University ofFlorida, C of Medicinc is seeking outstandingapplicants for a recendy received endowed chair innephrological research. TIhe endowed chair, with assetsin excess of $1 million, was established by the Statc ofFlorida's Eminent Scholars Program and was madc pos-sible by a generous contribution from a privatc donor.The individual who will fill the chair will have a full-timetenure-accruing faculty appointment in the Division ofNephrology, Hypension and Transplantation in theDepartmcnt of Medicine of the University of Florida

of Medicine. The appointee should have anM.D. or M.D./Ph.D. degree and an estblishd creatve,and productive rescarch pam. Appriate areas ofreearch, among others, iclude mo biob andbiochemistry, immunology, transport physiology,hypertension and cel biology. Appointment lve and adarycommensurate with education and experience. Anticipat-ed starting date is 1 July 1988. Interested individualsshould apply by 1 March 1988: James E. McGuian,MD., Chiman, Search mmitte, Chair in Neph-rolgical Resrch, D qent of Miie, Coleof Micine, Boa J-277, Uniy ofFrida HeaCenter, Gdneville, FL 32610. The Unimrsity fFloridai an Equal OppouiyAffin Action E oyer.

FACULTY OPENING IN PHYSICSUTNIVERSIITY OF CALIFORNIA

AT BERKELEY

Ihe Department of Physics of the University of Cali-fornia at Bey e s to make one appointment atthe assistant professor or tenured associate professorlevel, eflctive1July 1988, and nding budetayapproval. All fields of physics will 'be considac, butwith some cmphasison experimental partice physics andstatistical mecanics. There is a possibility ofa fellowshipfor one year of research before asumig the regularduties of an assistant professor.

Applicants should send curriculum vitae, bibliography,statement of research interesu, and list of refrences to:Profeor P. Buford Price, Chairman, Dep t ofPhysics, University of California at Ber, Berke-1e r CA 94720, before 1 February 1988. Unoj C;orxia wi an Equal Opp ity,A AonEmployer.

POSITIONS OPEN

ENDOWED PROFESSORSHIP INBIOLOGICAL OCEANOGRAPHYDUKE UNIVERSITY MARINE LAB

Applications and nominations are invited for the Har-vey W. Smith Chair and Biological Oceanography. Thisis a tenured full professorship with an endowed 9-monthsalary, plus fellowship funds for graduate and undergrad-uate students. The Smith Professor will be rcsident at theDuke Marine Laboratory, Beaufort, North Carolina, andwill hold a tenured appointment in an appropriatedepartment on the Durham Campus ofDuke University.

Applications are invited from leading biological ocean-ographers who would pursue a vigorous program ofresearch and tcadkins at Marine Laboratory. Excdl-lent opportunities aeist for interaction with faculty in theDuke Departments of Biochemistry, Botany, Geology,Physiology, and Zoology and the Schools ofEngineenngand Forestry and Environmental Studies. As well asother branches of the DukeIJNC Oceanography Con-sortium, the Consortium operates the RV cpHatterasand has an ecpcnsive pool ofoceanography instrumenta-tion.The dosing date for applications is 1 February 1988;

an appointment will be made by 1 July 1988. Applica-tions mduding a complete currculum vitae, reprnts ofsignificant recent pubications, a statement of researchinterest and the names of at least three references shouldbe sent to: Professor D. A. Livingstone, Deprtmntof Zoology, Duke Univesty, Durham, NC 27706;Telephone: 919-684-3264. Duke Univer is an EqualOpportusyAfiwarvAtion Employe

ENGINEERING FACULTY POSTON-TheDepartment ofEnvironmental Science and Engineering,George R. Brown School ofEngineering, Rice Universi-ty, invites applications for a tenure-track position at theassistant professor level, beginning 1 July 1988.

Applicants must be engrr with the Ph.D. orequiv-alent. An active r program and teaching at theundergraduate and graduate levels will be required.Research interests should be in the physical and chemicalprocesses ofwater and wastewater treatment, and the fateand transport oforganic and inorganic compounds in theenvironment. Salary is competitive and negotable.Send curriculum vitae to: Dr. C. H. Ward, Chair-

mang, De ent of Environmental Scincee and En-gineeing, Rice Unvrsity, P.O. Box 1892, Houston,TX 77251. Rice UUiver is anAffirnativeAasion/EqualOpportunyt Enmpoyer.

HARVARD UNIVERSITYENGINEERING FLUID MECHANICS

Applications and noninations are invited for a JUN-IO1 FACULTY POSMON in En ineeing FluidMechanics, to begin September 1988. The imtial ap-pointment will be for either 3 or 5 years. Candidatesshould have research interests spanning theory, computa-tion, and xperimnent. Areas ofs tion may indudc(but are not limited to): multi-pe flows; flows indud-ing particulate suspensions; non-Newtonian theology;stability and turbulencc; and flows contained by clxiblcboundaries. Applications may bar on problems in me-chanical, chemical, or biomedical englneering. Appli-cants should send curriculum vitae, incuding names ofthrce references, and a list ofpublicons to: P sorG F. Carrier, Carman, Fluid

Sr Commih Divioi of A-ad Scines,Harvard Univesty, Pierce Ha CambridgMA 02138.Harvd is an Equal OpportyAAction Emplyefr.

University ofToronto.EVOLUTIONARY BIOLO-GIST, Division of Life Sciences, Scarborough Campus.Applications are invited for a tenurc-track position at theassistnt profssor levlstar on 1 July 1988. Appli-cants should have experienc. The success-fil applicantwill be responsible for teaching undergradu-atc courscs in evolutionary biolgy and population c-nctics, and be expected to pursuers and to partci-gatc in the graduateprogram. Applicants should submit,

31 January 1988, curriculum vitae and arrange tohave three etters ofrefence sent to: Dr. R. BooChairofSearch Committee, Division ofLife Scences,Scarborugh Campus, Unieity of Toronto, 1265Military Tril, Scarboroug Ontario, Canada, MlC1A4. 7he Unsy encourges botb mex axd women toapy. In acnane with Caadian imm--vatn rqurio-menu, this advetisement is directd to Canadian ctise orpeae tidens ofCanada.

SCIENCE, VOL. 238

THE OREGON HELTHSCIENCES UNIVERSITYDIRECTOR, BIOMEDICAL

INFORATIONCOMMUNICATION CENTER

Applications are sought forDIRECrORof anew $20-million Biomedical Information Com-munication Center dedicated to the applicationof information technology to the heani arts.The center will include research in the ria-tion scicnces and the university library. Fundsare available for building cons equip-ment and research.Thc director should hold a doctorate and have

a record ofecperience, creativity and productivi-ty in research area such as medical iniforatics,automated information systems or the applica-tion of computers to medicine. Admnistativeexperience and management skills are essential.

Submit curriculum vitae, bibliography, andthree rcefrences by15 January 1988, to: ScottH. Goodnit, MD., BICC Search Commit-tee, L471, The Orgon Healh Sciences Uni-versity, Portland, OR 97201. Late applicationsmay be considered until the position iS flled.AnA nuativeAction/Equal EOpportnity Employer.

.

RESEARCH FELLOWSHIPS INNUTRITION FOR

MEDICAL STUDENTSTHE ROCKEFELLER UNIVERSITY

A new program for one year research fellow-ships has been made available by the PewCharitable Trusts. Up to six medical studentswill be selected to join the Pew Center ofNutritional Excellence at Rockefeller Universityin New York City. The core activity of fellows willbe investigative work in basic biomedical labo-ratories at Rockefeller University on projectsrelevant to human nutrition. Applicants shouldcurrently be in the junior year of any medicalschool in the U.S.A. A generous stipend andhousing allowance will be offered to thoseselected for the fellowship year to begin July 1,1988.

Applications must be completed no laterthan February 1, 1988 to allow for full consider-ation. A small number of applicants will beinvited to New York City for interviews in March,1988 and final selection will be made early inApril. For application forms and further detailswrite to:

DR. JULES HIRSCHTHE ROCKEFELLER UNIVERSITY

1230 YORK AVENUENEW YORK, NEW YORK 10021-6399

DevelodpmlentScientists

Join our team of bold thinkers in oneof the following research capacities.PRINCIPAL SCIENTIST-Responsibilities will entail assay developmentat the bench as well as the responsibility for 2-3 scientists. The success-ful candidate should have a Ph.D in Bioanalytical Chemistry or Biochemis-try with 3-5 years post doctoral experience preferably in an industrialsetting. In addition, experience in all areas of protein chemistry includingHPLC and immunoassays; and good wrinen and oral communicationskills are essential.POLYMER/PROTEIN CHEMIST-Responsibilities will include methodsdevelopment on complex protein mixtures with strong emphasis onHPLC. Requires a Ph.D in Analytical Chemistry, 3-5 years' post doctoralexperience (preferably industrial), and strong written and oral communica-tion skills. Some supervisory experience is desirable, but not essential.We offer a fully commensurate salary and attractive benefits package.Please forward your resume, indicating position of interest, in confidenceto: B. Van Vliet, Schering-Research, 2000 Galloping Hill Road, K61, E17,Kenilworth, NJ 07033. We are an equal opportunity employer.

Schering-Plough

.

iPostdoctora

Seeking innovative scien-tists for postdoctoralresearch appointments toadvance our position ofleadership in secondgeneration anti-idiotypicmonoclonal technology fortherapeutic applications.Publications encouraged.Ph.D. with experience inthe development of im-munotherapeutic agentsfor treatment of parasiticand virl diseasespreferred.Synbiotics offers an attrac-tive salary and benefitsprogram, as well as astimulating, highly-creative work environ-ment. Qualified in-dividuals should sendtheir resume, in strict con-fidence to: Vice PresidentR&D, 11011 Via Frontera,San Diego, CA 92127. Weare an equal opportunityemployer.

/SYNCATIONR

-l

.i

I

I -i

POSITIONS OPEN

FACULTY POSMIIONMOLECULAR PHARMACOLOGY/

TOXICOLOGYThe Department of Pharmacolgy, Northwestern

University Medical School, invites applications for atenure-track position at the assistant or associate profes-sor levdl. Candidates should have a Ph.D. or M.D.degree or equivalent, have had pos training, andhave demonstrated excellence m rsearch and commit-ment to teahing. Preference will be en to those whohave had experience in application o molecularbioboy,genetics, cell biolgy, or immunology to toxicolgicalproblems. Scnd curriculum vitae, the names of threereferences, and a brief statemcnt offiture research plansto: Dr. Toshio Narahashi, Profesor and airman,Dqertment ofPharmacology, Nothwen Univer-sity Medical School, 303 East Chkago Avenue, Chi-cago, IL 60611. Telephone: 312-90&-8284.An EqulOppounityLAjinnativeActi.m Emplyr.

FACUJLTY POSMON IN CHEMISTRYThc Department of Chemistry of The University of

Tulsa invites applications for a tenure-track positon inchemistry. The area of specalization is open, but candi-dates with exprtise in bochisty, polymerchemistry,catalysis, or analytical chemity would complement ecx-isting strengths. Applicants at all levels are welcome.Salary and start-up fing are compcetivc. Send curric-ulum vitae, a brief summary of research interests, andthree lets of rec dation to: Dr. Robert How-ard, Chairman, ofChmbtry,Uniof Tulsa, 600 Souls College, ulsa, OK 74104 by 1February 1988. The Un 1ives of Tulsaw f an EqualOppoeunyAfrmaivActo Emplye.FACULTY POSMON IN EYE RESEACH-

The D epartmnts of Oph ology and Anatomy ofThomas Jefferson University are an individual atthe Assistant Professor level for a joint tenure-trackappointment to these deparmts. Applicants shouldhave potdoctoral training an.d a demonstrabk ability toestab a strong and creative hresah program in anarea of visual or oculomotor bioly inc7uding, but notlimited to, areas of embryology, cell biolgy, bichemis-try, physiology, or mtor control Applsants are eciallyr sogt who cn applrmo&ofcellular and molecular biolto basc pobm ofoculomotor control. The Dwillas be expct-ed to interact with the clinifaculq and to particpatein teaching of graduate and medical students. In dapplicants shouild send curriculum vitae, a statement ofresearch plans, and objectives and three letters of refer-ence to: Dr. Gerald B. Grunwald, S ch mitteeChairman,D t of Anaomy, Thoms Jeffer-son Univrsity, 1020 Lout Street, Pildelphtia, PA19107. om tnUn ity is an EqualOpoiui-ty mativeAc n E .

GENERAL MANAGERMARINE TECHNOLOGY SOCIETY (MTS)The General Manager reports to the eected Society

President, and manages all headquarte activities andstaff in the Washington, D.C. locaile.The General Manager has fiscal responsibility for the

Society and assist in the preparation of the annualbudget. Duties include preparation and scrutiny of con-ference, section, committee and special proect budges,and maintenance of financial records for the Society.The General Manager is responsible for all policies and

procedures established by the Council, the ExecutiveCommittee, the President, and the By-Laws, and is thepnmary contact or those officers with the headquartersstaff. The General Manager will provide support servicesfor conferences and meeting as required and act asLiaison tO committee and section officers.MTS seeks an innovative, sdf-motivated individual

with good communication abilities and financal man-agement experience. Prior managment exnperience in aprofessional society is desirabk. Businessm texperience a must.

)Present position holder is cognizant of this solicitationand is a viabl candidate for the position.Send letter of application, rdsume, salry history and

requirements to:Mr. Morris A. Ransone

Director, Search i eInte Industries, Inc.

823 West StreetAnnapolis, MD 21401 1

POSITIONS OPEN

FACULTY POSMON INMOLECULAR BIOLOGY

The Department of Veterinary Pathobiology, TheOhio State University invites applications for a tenure-track position at the assistnt or associate professor level.The applicant should have a Ph.D. dgree with postdoc-toral researchexpericnce inmoleclar biolo andastrong commitment to research and graduate edcationResearch experience in biological sciences, veteinarymedn , or animal scince is desirable. Development ofan independent research program with extramural sup-port and collaborative research eflirts with faculty andgraduate students on animal and human health-relatedproblems is essetial. Applications should indude acurriculumvitae, list of publications, summaryofcufrentresearch activities, and names of at least fiour individualsfrom whom letters of reference may be solicited. Dead-line for receipt of applications is 1 March 1988. Addressall correspondence to: Dr. Charls Capen, Profesorand Charman, Department o V Pa bo-a ,Ihe Ohio State Univers, 1925 Coffey Road,C , OH 43210.The Obio State Uniqvety a an Equal Opportunity and

AfimatiAion Empoyer.

FACULTY POSMON: VETERINATRY/MI-CAL ENTOMOLOGIST. The Departmnt of Envi-ronnmntal Health has a tenure-trck position in veteri-nary/medical entomolOgy at assistant/associate profcssorlevel. Preference to dates with demonst eper-tise in the epidemiology of vector-borne disases. Thcsuccessful candidate Gwil develop a vigorous researchprogram, supervise graduat stucents, and participate inthe teahing program. A doctoral degree (Ph.D.,D.V.M., M).) and postdoctoral experien!crequired.Send curriculum vitac, statemnt of resear interests,and names of three refcrences by 15 February 1988 to:BarryJ. Beaty, D t ietofM obgy Cokla-do StateU ort C i, CO 80 . CSU ian Equal pActin Employr.

IMMUNOLOGISTMICROBIOLOAGISTFull-time tenure-track position in a nine-member biol-

ogy department. Masters required, Ph.D. p d.Eperence teaching at the college kvl p ; totea undergraduate microbiolgy, medica mirobiolo-gy, immunology, virology, and introductory biology.nitial review of applications bcegins 1 February 1988.Submit ktter of application, r6suni, three letters ofrecommendation, and unofficial transcipts to: Peron-nel Seices, Northeastem Ste Untvm , Tahle-quah, OK 74464. An Equal Op AActim Employer.

MICROBIOLOGISTAtmure-track assistant professorship is available in the

Wilkes Collegc Departmnnt ofBiology for a Microbiolo-gist Ph.D. required. Teaduing responsibilities indudeupper-leve electives in bactenology and immunologyand general microbiokgy for nurng majors. Teachingthe laboratory portion of a cell and molecular biologycourse may be required, and the possibility exists for thecandidate to develop an lectiveinhisherareaofinterestResearch with upper-level students is ncoraged andstudent advising is a requirement. The starting date is 1

ted in a modium-sized city in nothastem Penn-sylvania, Wilkes is a compprhensive, indepcndent, coodu-cational institution of about 2500 students, offiringbachelor's and masers degree progams in the arts andsciences, business saon, and engineering. Thecampus parallels the S u River and features anumber of stately turn-of-the century mansions, nowused as office and dormitory fclities. The science pro-gram a cts ounding stukdnts, possesses modlerlaboratories, and emphasizes superor taching through astrongly interactive approach tO learning.

Submlit curriculum vitae, a statement of intrests,copics ofgraduatc transcripts, and throe lctters ofrecom-mendation by 31 January 1988, to:

Dr. Loest J. Tuoz

Wilkes-Barre, PA 18766Telphone: 717-824-4651, extension 345

Wikes Colege t anAffirmatveActonEqualOpportun-ty Emplyer.

i6o8

POSITIONS OPEN

FACULTY POSMON IN NEUROBIOLOGYDARTMOUTH MEDICAL SCHOOL

Dartmouth Medical School is expanding in the area ofneuroscience through the establishment ofthe Center forMolocular and Chllar Medicinc. In conjunction withthis expansion, the Department of Biochemistry seeks anew faculy member with primary research interests inmolecular and/or cellular neurobiology. Thc individualwill be appointed at the assistant proeissor levd and willparticipate in the teaching activities of the departnent.AFplicants should submit curriculum vitae, a statementoJreearch interests and plans, and the names of threerefrences to: Searc Commit Dqm nt of Bio-chemistry, Dart h Medical School, Hanover,NH03756.DasouebMedie SSlo isanAffirmativeAaion/Equ Opportunity Empkoyer.

IMMUNOLOGISTTenure-track assistantassociate professor in the De-

partntofLife Sciences. Ph.D. with 2 years ofpostdoc-torl experience required. The candidate is expected toestablish a rsarch program and participate m under-graduate and graduate teaching. Applicants in any area ofimmunology will be considered; individuals with exper-tiSe in molecular immunology, immunogenetics andmechanism of pathogenesis or immunoregulation areencouraged to apply. Position available as early as June1988. In order to receive full consideration, curriculumvitae, hree lettcrs ofreference, and a summary ofcurrentand planned research interests should be sent by 18January 1988 to: Dr. William J. Brett Ch on,Deprtment of Life Sciences, Indiana State Unirsi-ty, erre Ha,utle, IN 47809. Indiana State Unirt isan Equa OpportnitylAfflnnativeAaion Employer.

MEDICAL MARKETING RESEARCHERS-Creative natural scicnces or psychology Ph.D.'s/M.S.'sneeded for caroers in health care marketing resarch/consulting. Positions require analytic prob[em-solving

comfort in working with groups of proessionals,excellent writing skills, and some statisucs. Our firmoffers an interesting altemative to an academic career,utilizing your researh skills in a creative and finandallyrewarding way. Rdsumes to: J. A. Cohen, Ph.D., Na-tioal Analyst, Diision of Booz-Allen and HamiltnInc., 400 aret Street, Philadelphia, PA 19106.AnAffirmativeAction Emplyfr.

MOLECULAR IMMUNOLOGIST with demon-strated exccllence in genetic analysis, doning, and ecpres-sion of genes coding for factors involved in immunesystem function and/or development. The successful can-didate must also possess a strong background in microbi-ology and interest in the alpplication of currcnt moleculartechniques tO the study ot animal diseases or immunopa-tholgy. Postdoctoral cxpericnce required. Undergradu-ate and graduate teaching consistent with other sciencefacult. Available 1 July 1988. Assistant professor, 12months, tenure track in Colleges of Sciencc and Agricul-tural Scicnces (Agricultural- Station). Appli-cation closing date:1 April 1988. Sen curriculum vitac,transcript, and three letters ofrcoommendation to: J. L.Fryer, C irman, Department ofMkrobiokloy, Ore-gon State Univesity, Corvllis, OR 97331-3804.OSU is anAffirtiveAion/Equal Opportuity Employerand cpian with Sectin 504 of the Rehiiation Act of1973.

Ph.D. BIOCHEMISr/IMMUNOLOGIST withminimum of 5 years of work expeience in proteinpurificatin, HPLC and SDS-PAGE c m , Ab- and ton (poly and Rmon X IA

and ELISA, phls additional exeince witi DNA probetechiqe for Dx assay delp n Et ial

and rewarded acrdin.0y by dis NewlCompany. Send ackuhim vitae, list of publications,and list ofrefces to: Box 185, SCIENCIL

Ph.D.-SURGERY: Surgical laboratory in Universi-ty-based surgical department seeks basic science research-er with Ph.D. in biochemistry, immunolgy, or physiol-ogy. Must be qualified for academic appoitment withspecific intcrest and cxpeincce in wound healing, elasdtinand/or collagen metabolisn. Competitive salary. Sendcurriculum vitae with salary history to: Marie Murtha,Employment Representate, Long Iland JewishMedial Center, Ncw Hyde Park, NY 11042. AnEqual Opponity Emploer.

SCIENCE, VOL. 238

* - - = -

ARTHRITIS RESEARCH BIOLOGISTSThe Upjohn Company is seeking to expand its arthritis research and drug discovery programwith the addition of two Ph. D. biologists. These scientists will join a multidisciplinary team withthe common objectives of understanding the autoimmune and inflammatory components ofthe arthritic process and to discover novel drugs for the therapy of human arthritic diseases.Candidates should have a Ph. D. degree in cell biology, immunology, pathology, physiologyor biochemistry. and have completed 1 -6 years of postdoctoral research. They should havean interest and/or experience in autoimmune disease research and in the drug discovery process.CONNECTIVE TISSUE BIOLOGISTThe successful candidate will establish a research program to study the regulation of connec-tive tissue cell function during the pathogenesis and tissue remodeling in arthritic diseases.The influence of leukocytes and cytokines, such as interieulin-1, on the function of chondrocytes,osteoclasts, and osteoblasts in the arthritic joint would be of primary interest.Basic research will be integrated with the establishment of model systems for the discoveryof drugs which ameliorate the arthritic process by regulation of connective tissue biology.MACROPHAGE IMMUNOLOGISTWe are seeking a biologist to establish a research and drug discovery program on the roleof macrophages or other accessory cells, in autoimmunity and inflammation. We are particLarlyinterested in the roll of cell surface Ia expression and antigen presentation in the regulationof normal and aberrant immune responses. Other areas of interest include understanding andregulation of macrophage-mediated functions in inflammation; secretion of monokines, suchas interieukin-1 and other immunoregulatory or inflammatory products; or the genetic regula-tion of macrophage function in immune responsiveness.Kalamazoo is a medium-sized Southwestern Michigan community with immediate access toa mix of excellent cultural, educational and recreational pursuits, including numerous lakes anda four-season climate. Upjohn offers a very competitive salary, commensurate with experienceand an outstanding benefits program.For confidential consideration, please call toll free 1/800/253-8600, ext. 3-6767, (insideMichigan call collect 616/323-6767) to request an employment application be sent to you.Please refer to Ad Number 1495 when calling.

An Equal Employment Opportunity Employer M/FOur commitment to scientific excellence continues...

ASSOCIATE DIRECTORCellular and Molecular Biology

Merck Sharp & Dohme Research Laboratories' expanding long-term commitment tomolecular and cellular biology has created the opportunity for a position of strongleadership. We seek a talented and experienced scientist to accept the responsibilityfor leading a group of 10 molecular biologists within projects in both research as wellas product development. These multidisciplinary programs will be collaborative ef-forts within the research laboratories which utilize techniques in molecular andcellular biology for the cloning, identification and analysis of proteins of therapeutic,pharmacologic, or process development interest as well as the control of expressionof such proteins.

The successful candidate possesses broad experience in a range of areas ofmolecular biology which include: regulation of gene expression, cDNA cloning andexpression in eukaryotic host systems, viral vectors, structure/function studies ofproteins, scale-up of recombinant mammalian cells, and protein analytical andpurification techniques. Demonstrated research independence, 7+ years post-doctoral research, extensive supervisory experience, and an excellent publicationrecord in molecular biology are all required. Strong communication and leadershipskills, a desire to work as part of a multi- disciplinary team, and the ability to developthe talents of other scientists are very important. Industrial experience is a plus.

This position will provide an outstanding opportunity to implement novel research pro-jects with the potential for significant impact in several areas of human health. Col-laborations with other research departments will offer the opportunity for high visibilityand career growth. We encourage broad interactions with the scientific community atlarge through collaborations, publications, and presentations at major scientific con-ferences. Additionally, a successful leader would be expected to be able to expandfuture responsibilities in this dynamic position.

Excellent salary, broad benefits, and generous relocation entitlements accompany thisposition in our new and spacious laboratories in Rahway, New Jersey. In confidence,please send your resume, four professional references whom we may contact, andsalary history and requirements to: Mr. Jacques P. Kueny, MERCK SHARP & DOHMERESEARCH LABORATORIES, West Point, PA 1948. EEO/AANVH/Employer.

THE CHINESE UNIVERSITY OF HONG KONGApplications are invited for the following post:

LECTURER IN PHARMACOLOGYThe Department of Pharmacology teaches a one-yearpharmacology course in the pre-clinical part of theMedical Course of the University, and participates in jointor integrated sessions on various topics forming part ofthe clinical teaching. The research fields in which theDepartment is currently engaged and for which it isequipped include drug metabolism, human and animalpharmacokinetics, transmitter substances, CNS pharma-cology and molecular pharmacology. Applicants shouldhave a doctorate in pharmacology or a related field, or amedical qualification, and strong interest in becomingpart of a team teaching medical pharmacology. (Theintroduction of a science pharmacology course is unlikely.)The expected date of assumption of duty is August 1, 1988or as soon as possible thereafter.

Annual Salary:

HK$188,040-213,420 by 2 increments BARHK$226,080-314,340 by 7 increments(approx. exchange rate: £1 = HK$12.90; US$1= HK$7.8)Starting salary will depend on qualifications and experi-ence.

Conditons of Service: Benefits include long leave, annualleave, sick leave, superannuation (University 15% ofsalary; appointee 5%), medical benefits, education allow-ance for children, and housing allowance for an appointeewhose annual salary is HK$200,760 or above. An appoin-tee on overseas terms will have passage benefits forhimself/herself and his/her dependants as well.

Application procedure: Applications should be made outin duplicate, giving full particulars, experience as well asthe names and addresses of three referees, and senttogether with copies of certificates/diplomas, testimonialsand recent publications to the Personnel Section, TheChinese University of Hong Kong, Shatin, Hong Kongbefore Jan. 15, 1987. Please quote reference number 91/509/2/87 and mark 'Recrultment' on cover.

I

+$IDEONIDEON CORPORATION is a newbiotechnology research and develop-ment company located in RedwoodCity, CA. IDEON's research focuseson the development of productsusing anti-idiotypic monoclonal anti-bodies and novel immunomodula-tors. Ideon is seeking experiencedscientists to play key roles in buildingthis exciting new enterprise.IMMUNOCHEMIST- Ph.D. in Bio-chemistry or Immunology with 3 +years of post-doctoral experience.Expertise in the chemistry of anti-bodies and peptide antigens,immunoassays and contemporarymonoclonal antibody technologies.MOLECULAR IMMUNOLOGIST -Ph.D. in Molecular Biology orImmunology with 3 + years of post-doctoral experience. Expertise in themolecular biology of immunoglobu-lins and/or immunoregulatorymolecules.Qualified candidates will have an opportunity tojoin a start-up company with the added strengthof pharmaceutical manufacturing capability pro-vided by IDEON's affiliation with INVITAONCORP. IDEON CORPORATION offers excellentsalary, equity participation, and other benefits.An equal opportunit