1Million Cups PresentationGerold Feuer, Ph.D.

Founder, Chief Scientific OfficerMarch 1, 2016

www.humurine.com

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ProblemImmuno-oncology is revolutionizing cancer treatments ($16.55 bn by 2020) and these new drugs need to be tested for safety and efficacy in proper animal model

Our MissionSave lives from cancer by accelerating new immunotherapies to market

Our Business ModelConduct research for safety and effectiveness of immunotherapies on behalf of pharmaceutical companies

Total HuMurine Revenues: 2014 $187,504 2015 $288,822 2016 $614,134

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Who We AreBiotechnology company formed as a “spinoff” from Feuer SUNY Upstate Medical University academic lab (Syracuse, NY)

Started research on humanized mice at UCLA Medical Center (1992) & continued as a tenured Professor at SUNY Upstate Medical University

2011 UC Davis Medical Center “Industry Partner”

2015 Feuer SUNY retirement & joined HuMurine full-time in Sacramento

Highly trained scientific staff (Ph.D.-level) with more than combined 40 years of experience in ‘humanized’ mouse models

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Generating The Highest Quality Humanized Mouse

Better HumanStem Cells…

Better Humanizedmice…

Better flow cytometryanalysis

Using Proprietary Technology to Create a Humanized Mouse Platform that Vastly Outperforms All Competitors

Test Safety and Efficacy of

Immunotherapies

“Humanized” Mice for Cancer Research

“Humanized” immune system mouse with human

tumors

Human ‘Avatar’ leukemia models (AML)

HuMurine creates ‘Avatar’ mice of a patients with cancer to concurrently test the efficacy of immunotherapies while the patient undergoes treatment

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State of the Art FacilitiesUC Davis Institute For Regenerative Cures Vivarium

Flow Cytometry CoreWet Lab Space

Oak ParkBldg.

your LOGO www.humurine.com

SBIR Award from the National Cancer Institute(May 2016)

HuMurine’s Hu-3GM(TM) mouse provides the only animal model with a human immune system to test efficacy and safety of new checkpoint inhibitors

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Current HuMurine ClientsHuMurine’s reputation for superior quality humanized mice and CRO services, has

enabled the company to establish and develop relationships with leading pharmaceutical firms and government agencies. Our expertise in the field positions

HuMurine for significant growth and expansion in 2018.

Companies Seeking HuMurine Services

HuMurine is Seeking Partnerships & Investment Capital Due to Increasing Demand for Services

Thank Youwww.humurine.com