Alcaçuz - Glycyrrhiza glabra L. - Ervas medicinais - Ficha Completa Ilustrada
Glycyrrhiza
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Transcript of Glycyrrhiza
1. Family: Leguminosae
2. Distribution: England, France, Germany,
USA, Italy, India, Russia, Spain
3. Origin: Greece
PPRC/INDIA 03
4. Meaning: Glycyrrhiza – sweet root
glabra – smooth
5. Etyology: also known as Liquorice plant
6. Flowers: Purplish blue colour
PPRC/INDIA 04
5. Underground portion: branches of long
roots + thin rhizomes (stolons)
6. Propagation: by rhizome cuttings
7. For drug prep: dried unpeeled roots &
stolons are used
PPRC/INDIA 05
1. Glycyrrhizin (2 – 14%) – triterpenoid
saponin
2. Major constituent: Glycyrrhizinic acid
3. Glabranin A & B
PPRC/INDIA 07
10. Formononetin
11. Glabrone
12. Hispaglaridin A & B
13. Coumarins: herniarin, umbelliferone
PPRC/INDIA 10
14. Triterpene sterols: onocerin,
betaamyrin, stigmasterol
15. Sugars: glucose, sucrose
16. Asparagine
PPRC/INDIA 11
1. Used as demulcent & expectorant
2. Liquid extract used in cough mixtures
3. Liquid extract used as flavouring agent
in nauseous medicines
PPRC/INDIA 18
4. Used as a substitute for corticosteroids
5. For peptic ulcers
6. Used in skin diseases
PPRC/INDIA 19
7. Commercially liquorice added to
chewing gum, chocolate candy,
cigarettes smoking mixture &
chewing tobacco
PPRC/INDIA 20
Glycyrrhetic acid, the metabolite of
Glycyrrhizin can inhibit 11-
betahydroxy steroid dehydrogenase in
kidney & thereby cause
pseudoaldosteronism resulting in
hypertension, hypokalemic myopathy,
arrythmia & cardiac arrest
PPRC/INDIA 22