資料5 令和元年度 業績令和元年度 業績 【1】原 著 Fukushi JI, Tsushima H,...

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令和元年度 業績 【1】原 Fukushi JI, Tsushima H, Matsumoto Y, Mitoma C, Furue M, Miyahara H, Nakashima Y. Influence of dioxin-related compounds on physical function in Yusho incident victims. Heliyon. 2019 Oct 23;5(10):e02702. Hashimoto-Hachiya A, Tsuji G, Furue M. Antioxidants cinnamaldehyde and Galactomyces fermentation filtrate downregulate senescence marker CDKN2A/p16INK4A via NRF2 activation in keratinocytes. J Dermatol Sci. 2019 Oct;96(1):53-56. Sadakane A, Landes RD, Sakata R, Nagano J, Shore RE, Ozasa K: Medical radiation exposure among atomic bomb survivors: understanding its impact on risk estimates of atomic bomb radiation. Radiat Res 191:507-517, 2019 Kajitani K, Tsuchimoto R, Nagano J, Nakao T: Relevance of hoarding behavior and the traits of developmental disorders among university students: A self-reported assessment study. BioPsychoSoc Med 13:13, 2019 Yamamoto N, Maruyama T, Masaki Y, Nagano J, Irie M, Kajitani K, Tsuchimoto R, Sato T: Contributions of anthropometrics and lifestyle to blood pressure in Japanese university students: Investigation by annual health screening. J Med Invest 67:174-181, 2020 Hsuan Chung, Satoshi Tajiri, Mai Hyoguchi, Riho Koyanagi, Akihiro Shimura, Fuyuko Takata, Shinya Dohgu, Toshiro Matsui: Analysis of catecholamines and their metabolites in mice brain by liquid chromatography-mass spectrometry using sulfonated mixed-mode copolymer column. Anal. Sci., 35(4), 433-439 (2019). Huu-Nghi Nguyen, Mitsuru Tanaka, Baorui Li, Tomoya Ueno, Hideki Matsuda and Toshiro Matsui: Novel in situ visualisation of rat intestinal absorption of polyphenols via matrix-assisted laser desorption/ionisation mass spectrometry imaging. Sci. Rep., 9(1), 3166 (2019). Akira Tsujita, Hidehiko Okazaki, Asami Nagasaka, Akinaga Gohda, Mitsushi Matsumoto, Toshiro Matsui: A new and sensitive method for quantitative determination of helium in human blood by gas chromatography–mass spectrometry using naturally existing neon-21 as internal standard. Forensic Toxicology, 37(1), 75-81 (2019). Mitsuru Tanaka, Shinya Dohgu, Genki Komabayashi, Hayato Kiyohara, Fuyuko Takata, Yasufumi Kataoka, Takashi Nirasawa, Motohiro Maebuchi, Toshiro Matsui: Brain-transportable dipeptides across the blood-brain barrier in mice. Sci. Rep., 9(1), 5769 (2019). 資料5

Transcript of 資料5 令和元年度 業績令和元年度 業績 【1】原 著 Fukushi JI, Tsushima H,...

Page 1: 資料5 令和元年度 業績令和元年度 業績 【1】原 著 Fukushi JI, Tsushima H, Matsumoto Y, Mitoma C, Furue M, Miyahara H, Nakashima Y. Influence of dioxin-related compounds

令和元年度 業績

【1】原 著

Fukushi JI, Tsushima H, Matsumoto Y, Mitoma C, Furue M, Miyahara H, Nakashima Y. Influence of dioxin-related

compounds on physical function in Yusho incident

victims. Heliyon. 2019 Oct 23;5(10):e02702.

Hashimoto-Hachiya A, Tsuji G, Furue M. Antioxidants cinnamaldehyde and Galactomyces fermentation filtrate

downregulate senescence marker

CDKN2A/p16INK4A via NRF2 activation in keratinocytes. J Dermatol Sci. 2019 Oct;96(1):53-56.

Sadakane A, Landes RD, Sakata R, Nagano J, Shore RE, Ozasa K: Medical radiation exposure among atomic bomb

survivors: understanding its impact on risk estimates of atomic bomb radiation. Radiat Res 191:507-517, 2019

Kajitani K, Tsuchimoto R, Nagano J, Nakao T: Relevance of hoarding behavior and the traits of developmental disorders

among university

students: A self-reported assessment study. BioPsychoSoc Med 13:13, 2019

Yamamoto N, Maruyama T, Masaki Y, Nagano J, Irie M, Kajitani K, Tsuchimoto R, Sato T: Contributions of

anthropometrics and lifestyle to blood pressure in Japanese university students: Investigation by annual health screening.

J Med Invest 67:174-181, 2020

Hsuan Chung, Satoshi Tajiri, Mai Hyoguchi, Riho Koyanagi, Akihiro Shimura, Fuyuko Takata, Shinya Dohgu,

Toshiro Matsui: Analysis of catecholamines and their metabolites in mice brain by liquid chromatography-mass

spectrometry using sulfonated mixed-mode copolymer column. Anal. Sci., 35(4), 433-439 (2019).

Huu-Nghi Nguyen, Mitsuru Tanaka, Baorui Li, Tomoya Ueno, Hideki Matsuda and Toshiro Matsui: Novel in situ

visualisation of rat intestinal absorption of polyphenols via matrix-assisted laser desorption/ionisation mass spectrometry

imaging. Sci. Rep., 9(1), 3166 (2019).

Akira Tsujita, Hidehiko Okazaki, Asami Nagasaka, Akinaga Gohda, Mitsushi Matsumoto, Toshiro Matsui: A new and

sensitive method for quantitative determination of helium in human blood by gas chromatography–mass spectrometry

using naturally existing neon-21 as internal standard. Forensic Toxicology, 37(1), 75-81 (2019).

Mitsuru Tanaka, Shinya Dohgu, Genki Komabayashi, Hayato Kiyohara, Fuyuko Takata, Yasufumi Kataoka, Takashi

Nirasawa, Motohiro Maebuchi, Toshiro Matsui: Brain-transportable dipeptides across the blood-brain barrier in mice.

Sci. Rep., 9(1), 5769 (2019).

資料5

Page 2: 資料5 令和元年度 業績令和元年度 業績 【1】原 著 Fukushi JI, Tsushima H, Matsumoto Y, Mitoma C, Furue M, Miyahara H, Nakashima Y. Influence of dioxin-related compounds

Nobuhiro Tahara, Ruchia Kojima, Risa Yoshida, Munehisa Bekki, Yoichi Sugiyama, Tomohisa Nakamura, Jiahui Sun,

Akihiro Honda, Atsuko Tahara, Sachiyo Igata, Yuki Kumashiro, Takanori Matsui, Yoshihiro Fukumoto, Toshiro Matsui,

Sho-ichi Yamagishi: Serum levels of protein-bound methylglyoxal-derived hydroimidazolone-1 are independently

correlated with asymmetric dimethylarginine. Rejuvenation Res., 22(5), 431-438 (2019).

Yoshiyuki Miyazaki, Yuri Iwaihara, Juneha Bak, Hayato Nakano, Shugo Takeuchi, Hideaki Takeuchi, Toshiro Matsui,

Daisuke Tachikawa: The cooperative induction of macrophage activation by fucoidan derived from Cladosiphon

okamuranus and -glucan derived from Saccharomyces cerevisiae. Biochem. Biophys. Res. Commun., 516, 245-250

(2019).

Alexia M. Nectoux, Chizumi Abe, Shu-Wei Huang, Naoto Ohno, Junji Tabata, Yuji Miyata, Kazunari Tanaka, Takashi

Tanaka, Haruo Yamamura, Toshiro Matsui: Absorption and metabolic behavior of hesperidin (rutinosylated hesperetin)

after single oral administration to Sprague-Dawley rat. J. Agric. Food Chem., 67(35), 9812-9819 (2019).

Ohara, C Sekiguchi, A Sudo, N et al.

Effectiveness of enhanced cognitive behavior therapy for bulimia nervosa in Japan: a randomized controlled trial

protocol

BIOPSYCHOSOCIAL MEDICINE.14: 2. 2020

Takakura, S. Aso, CS. Sudo, N et al.

Physical and psychological aspects of anorexia nervosa based on duration of illness: a cross-sectional study

BIOPSYCHOSOCIAL MEDICINE.13:32. 2019

Takakura, S . Oka, T . Sudo, N

Changes in circulating microRNA after recumbent isometric yoga practice by patients with myalgic

encephalomyelitis/chronic fatigue syndrome: an explorative pilot study

BIOPSYCHOSOCIAL MEDICINE.13: 29. 2019

Nishihara, T . Nozaki, T . Sudo, N et al.

Effects of Weight Loss on Sweet Taste Preference and Palatability following Cognitive Behavioral Therapy for Women

with Obesity

OBESITY FACTS. 12: 529-542. 2019

Hata, T . Miyata, N . Sudo, N et al.

The Gut Microbiome Derived From Anorexia Nervosa Patients Impairs Weight Gain and Behavioral Performance

in Female Mice

ENDOCRINOLOGY.160: 2441-2452. 2019

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Sudo, N

Biogenic Amines: Signals Between Commensal Microbiota and Gut Physiology

FRONTIERS IN ENDOCRINOLOGY.10: 504. 2019

Furukawa, T .Nakano, H. Sudo, N et al.

Predictors of objectively measured snoring in a working population

SLEEP AND BIOLOGICAL RHYTHMS.17: 349-354.2019

Miki Fujiwara, Daichi Kuwahara, Masahiro Hayashi, Takeshi Zendo, Masao Sato, Jiro Nakayama, Kenji Sonomoto,

Lowering effect of viable Pediococcus pentosaceus QU 19 on the rise in postprandial glucose, Bioscience of Microbiota,

Food and Health, 39, 57-64, 2020.

Masanori Fukao, Takeshi Zendo, Takuro Inoue, Nobuo Fuke, Tomoo Moriuchi, Yasuhiro Yamane, Jiro Nakayama, Kenji

Sonomoto, Tetsuya Fukaya, Relation between cell-bound exopolysaccharide production via plasmid-encoded genes and

rugose colony morphology in the probiotic Lactobacillus brevis KB290, Animal Science Journal, 90, 1575-1580, 2019.

Masanori Fukao, Takeshi Zendo, Takuro Inoue, Jiro Nakayama, Shigenori Suzuki, Tetsuya Fukaya, Nobuhiro Yajima, Kenji

Sonomoto, Plasmid-encoded glycosyltransferase operon is responsible for exopolysaccharide production, cell aggregation,

and bile resistance in a probiotic strain, Lactobacillus brevis KB290, Journal of Bioscience and Bioengineering, 128, 391-

397, 2019.

Mugihito Oshiro, Rie Momoda, Masaru Tanaka, Takeshi Zendo, Jiro Nakayama, Dense tracking of the dynamics of the

microbial community and chemicals constituents in spontaneous wheat sourdough during two months of backslopping,

Journal of Bioscience and Bioengineering, 128, 170-176, 2019.

M. Nakphaichit, S. Sobanbua, S. Siemuang, W. Vongsangnak, Jiro Nakayama, S. Nitisinprasert, Protective effect of

Lactobacillus reuteri KUB-AC5 against salmonella enteritidis challenge in chickens, Beneficial Microbes, 10, 43-54, 2019..

Hiroshi Hamajima, Masaru Tanaka, Miyuki Miyagawa, Mayuko Sakamoto, Tsuyoshi Nakamura, Teruyoshi Yanagita,

Megumi Nishimukai, Susumu Mitsutake, Jiro Nakayama, Koji Nagao, Hiroshi Kitagaki, Koji glycosylceramide commonly

contained in Japanese traditional fermented foods alters cholesterol metabolism in obese mice, Bioscience, Biotechnology

and Biochemistry, 83, 1514-1522, 2019.

Masaru Tanaka, Masafumi Sanefuji, Seiichi Morokuma, Misako Yoden, Rie Momoda, Kenji Sonomoto, Masanobu Ogawa,

Kiyoko Kato, Jiro Nakayama, The association between gut microbiota development and maturation of intestinal bile acid

metabolism in the first 3 y of healthy Japanese infants, Gut Microbes, 2, 205-216, 2020.

Sean Littlewood, Helena Tattersall, Charlotte S. Hughes, Rohanah Hussain, Pikyee Ma, Stephen E. Harding, Jiro Nakayama,

Page 4: 資料5 令和元年度 業績令和元年度 業績 【1】原 著 Fukushi JI, Tsushima H, Matsumoto Y, Mitoma C, Furue M, Miyahara H, Nakashima Y. Influence of dioxin-related compounds

Mary K. Phillips-Jones, The gelatinase biosynthesis-activating pheromone binds and stabilises the FsrB membrane protein

in Enterococcus faecalis quorum sensing, FEBS Letters, 594, 553-563, 2019.

Tomiyama H, et al. Brachial-Ankle Pulse Wave Velocity Versus Its Stiffness Index β-Transformed Value as Risk Marker

for Cardiovascular Disease. J Am Heart Assoc. 2019 Dec 17;8(24):e013004

Asada M, et al. Serum Lipopolysaccharide-Binding Protein Levels and the Incidence of Cardiovascular Disease in a

General Japanese Population: The Hisayama Study. J Am Heart Assoc. 2019 Nov 5;8(21):e013628

Honda T, et al. Serum elaidic acid concentration and risk of dementia: The Hisayama Study. Neurology. 2019 Nov

26;93(22):e2053-e2064

Sasaki T, et al. Estimation of nephron number in living humans by combining unenhanced computed tomography with

biopsy-based stereology. Sci Rep. 2019 Oct 7;9(1):14400

Nagata T, et al. NT-proBNP and Risk of Dementia in a General Japanese Elderly Population: The Hisayama Study. J Am

Heart Assoc. 2019 Sep 3;8(17):e011652

Fujiwara K, et al. Long-term regular exercise and intraocular pressure: the Hisayama Study. Graefes Arch Clin Exp

Ophthalmol. 2019 Nov;257(11):2461-2469

Higashioka M, et al. Ratios of serum eicosapentaenoic acid to arachidonic acid and docosahexaenoic acid to arachidonic

acid were inversely associated with serum resistin levels: The Hisayama Study. J Diabetes Investig. 2020 Mar;11(2):482-

489

Kageyama S, et al. Characteristics of the Salivary Microbiota in Patients With Various Digestive Tract Cancers. Front

Microbiol. 2019 Aug 2;10:1780

Ueda E, et al. Trends in the Prevalence of Myopia and Myopic Maculopathy in a Japanese Population: The Hisayama Study.

Invest Ophthalmol Vis Sci. 2019 Jul 1;60(8):2781-2786

Hamasaki H, et al. Tauopathy in basal ganglia involvement is exacerbated in a subset of patients with Alzheimer's disease:

The Hisayama study. Alzheimers Dement (Amst). 2019 Jun 6;11:415-423

Hashimoto S, et al. Association between Axial Length and Myopic Maculopathy: The Hisayama Study. Ophthalmol

Retina. 2019 Oct;3(10):867-873

Malik R, et al. Publisher Correction: Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci

associated with stroke and stroke subtypes. Nat Genet. 2019 Jul;51(7):1192-1193

Hata J, et al. Association Between Serum ホイ-Alanine and Risk of Dementia. Am J Epidemiol. 2019 Sep 1;188(9):1637-

1645

Ninomiya T, et al. Serum Ethylamine Levels as an Indicator of l-Theanine Consumption and the Risk of Type 2 Diabetes

in a General Japanese Population: The Hisayama Study. Diabetes Care. 2019 Jul;42(7):1234-1240

Page 5: 資料5 令和元年度 業績令和元年度 業績 【1】原 著 Fukushi JI, Tsushima H, Matsumoto Y, Mitoma C, Furue M, Miyahara H, Nakashima Y. Influence of dioxin-related compounds

Yoshida D, et al. Dairy consumption and risk of functional disability in an elderly Japanese population: the Hisayama Study.

Am J Clin Nutr. 2019 Jun 1;109(6):1664-1671

Izumaru K, et al. Reduced Estimated GFR and Cardiac Remodeling: A Population-Based Autopsy Study. Am J Kidney Dis.

2019 Sep;74(3):373-381

Marklund M, et al. Biomarkers of Dietary Omega-6 Fatty Acids and Incident Cardiovascular Disease and Mortality.

Circulation. 2019 May 21;139(21):2422-2436

Fujiwara K, et al. Glucose Tolerance Levels and Circumpapillary Retinal Nerve Fiber Layer Thickness in a General

Japanese Population: The Hisayama Study. Am J Ophthalmol. 2019 Sep;205:140-146

Inaishi J, et al. Association Between Genetic Risk and Development of Type 2 Diabetes in a General Japanese Population:

The Hisayama Study. J Clin Endocrinol Metab. 2019 Aug 1;104(8):3213-3222

Yang Y, et al. Dietary Inflammatory Index Positively Associated With High-Sensitivity C-Reactive Protein Level in

Japanese From NIPPON DATA2010. J Epidemiol. 2020 Feb 5;30(2):98-107

Jardine MJ, et al. Dietary Sodium Reduction Reduces Albuminuria: A Cluster Randomized Trial. J Ren Nutr. 2019

Jul;29(4):276-284

Wong MG, et al. Physical component quality of life reflects the impact of time and moderate chronic kidney disease, unlike

SF-6D utility and mental component SF-36 quality of life: An AusDiab analysis. Nephrology (Carlton). 2019

Jun;24(6):605-614

Oku S, et al. Disrupted tongue microbiota and detection of nonindigenous bacteria on the day of allogeneic hematopoietic

stem cell transplantation. PLoS Pathog. 2020 Mar 9;16(3):e1008348

Inaishi J, et al. Association of glucose tolerance status with pancreatic beta- and alpha-cell mass in community-based

autopsy samples of Japanese individuals: The Hisayama Study. J Diabetes Investig. 2020 Feb 7

Hachiya T, et al. Genome-Wide Polygenic Score and the Risk of Ischemic Stroke in a Prospective Cohort: The Hisayama

Study. Stroke. 2020 Mar;51(3):759-765

Ohara T, et al. Elevated serum glycated albumin and glycated albumin hemoglobin A(1c) ratio were associated with

hippocampal atrophy in a general elderly population of Japanese: The Hisayama Study. J Diabetes Investig. 2020 Jan 30

Sakata S, et al. Serum uric acid levels and cardiovascular mortality in a general Japanese population: the Hisayama Study.

Hypertens Res. 2020 Jan 17

Higashioka M, et al. Ratios of serum eicosapentaenoic acid to arachidonic acid and docosahexaenoic acid to arachidonic

acid were inversely associated with serum resistin levels: The Hisayama Study. J Diabetes Investig. 2020 Mar;11(2):482-

489

Yang Y, et al. Dietary Inflammatory Index Positively Associated With High-Sensitivity C-Reactive Protein Level in

Japanese From NIPPON DATA2010. J Epidemiol. 2020 Feb 5;30(2):98-107

Page 6: 資料5 令和元年度 業績令和元年度 業績 【1】原 著 Fukushi JI, Tsushima H, Matsumoto Y, Mitoma C, Furue M, Miyahara H, Nakashima Y. Influence of dioxin-related compounds

Hatabe Y, et al. Decline in Handgrip Strength From Midlife to Late-Life is Associated With Dementia in a Japanese

Community: The Hisayama Study. J Epidemiol. 2020 Jan 5;30(1):15-23

Ishikawa M, Williams G, Forcinito P, Ishikawa M, Petrie RJ, Saito K, Fukumoto S, Yamada Y. Pannexin 3 ER Ca2+ channel

gating is regulated by phosphorylation at the Serine 68 residue in osteoblast differentiation. Sci Rep. 9(1):18759, 2019.

Miyazaki A, Sugimoto A, Yoshizaki K, Kawarabayashi K, Iwata K, Kurogoushi R, Kitamura T, Otsuka K, Hasegawa T,

Akazawa Y, Fukumoto S, Ishimaru N, Iwamoto T. Coordination of WNT signaling and ciliogenesis during odontogenesis

by piezo type mechanosensitive ion channel component 1. Sci Rep. 9(1):14762, 2019.

Manome A, Abiko Y, Kawashima J, Washio J, Fukumoto S, Takahashi N. Acidogenic Potential of Oral Bifidobacterium

and Its High Fluoride Tolerance. Front Microbiol. 10:1099, 2019.

Tanaka Y, Fukumoto S, Sugawara S. Mechanisms underlying the induction of regulatory T cells by sublingual

immunotherapy. J Oral Biosci. 61(2):73-77, 2019.

Yamaguchi-Ueda K, Akazawa Y, Kawarabayashi K, Sugimoto A, Nakagawa H, Miyazaki A, Kurogoushi R, Iwata K,

Kitamura T, Yamada A, Hasegawa T, Fukumoto S, Iwamoto T. Combination of ions promotes cell migration via

extracellular signal regulated kinase 1/2 signaling pathway in human gingival fibroblasts. Mol Med Rep. 19(6):5039-5045,

2019.

Nonaka K, Han X, Kato H, Sato H, Yamaza H, Hirofuji Y, Masuda K. Novel gain-of-function mutation of TRPV4

associated with accelerated chondrogenic differentiation of dental pulp stem cells derived from a patient with metatropic

dysplasia. Biochem Biophys Rep. 19:100648, 2019.

Nguyen Nguyen HT, Kato H, Sato H, Yamaza H, Sakai Y, Ohga S, Nonaka K, Masuda K. Positive effect of exogenous

brain-derived neurotrophic factor on impaired neurite development and mitochondrial function in dopaminergic neurons

derived from dental pulp stem cells from children with attention deficit hyperactivity disorder. Biochem Biophys Res

Commun. 513(4):1048-1054, 2019.

Tanaka Y, Sonoda S, Yamaza H, Murata S, Nishida K, Kyumoto-Nakamura Y, Uehara N, Nonaka K, Kukita T, Yamaza T.

Acetylsalicylic Acid Treatment and Suppressive Regulation of AKT Accelerate Odontogenic Differentiation of Stem Cells

from the Apical Papilla. J Endod. 45(5):591-598, 2019.

Takahashi Y, Yuniartha R, Yamaza T, Sonoda S, Yamaza H, Kirino K, Yoshimaru K, Matsuura T, Taguchi T. Therapeutic

potential of spheroids of stem cells from human exfoliated deciduous teeth for chronic liver fibrosis and hemophilia A.

Pediatr Surg Int. 35(12):1379-1388, 2019

Mayumi Tsuji, Eiji Shibata, David J. Askew, Seiichi Morokuma, Yukiyo Aiko, Ayako Senju, Shunsuke Araki,

Masafumi Sanefuji, Yasuhiro Ishihara, Rie Tanaka, Koichi Kusuhara, Toshihiro Kawamoto and Japan Environment and

Children’s Study Group.

Associations between metal concentrations in whole blood and placenta previa and placenta accreta: the Japan Environment

and Children’s Study (JECS)

Environmental Health and Preventive Medicine. 2019. doi: org/10.1186/s12199-019-0795-7

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Sachiko Iwata, Masahiro Kinoshita, Fumie Fujita, Kennosuke Tsuda, Mitsuaki Unno, Takashi Horinouchi, Seiichi

Morokuma, Shinji Saitoh, Osuke Iwata.

Peripartum depression and infant care, sleep and growth

Sci Rep. 2019. Jul 15;9(1):10186. doi: 10.1038/s41598-019-46563-4.

Tanaka M, Sanefuji M, Morokuma S, Yoden M, Momoda R, Sonomoto K, Ogawa M, Kato K, Nakayama J.

The association between gut microbiota development and maturation of intestinal bile acid metabolism in the first 3 y of

healthy Japanese infants.

Gut Microbes. 2019 Sep 24:1-12. doi: 10.1080/19490976.2019.1650997. [Epub ahead of print]

Michikawa T, Yamazaki S, Shimizu A, Nitta H, Kato K, Nishiwaki Y, Morokuma S. Exposure to Asian dust within a few

days of delivery is associated with placental abruption in Japan:

a case-crossover study. BJOG. 2019 Oct 26. doi: 10.1111/1471-0528.15999. [Epub ahead of print]

Myoga M, Tsuji M, Tanaka R, Shibata E, Askew DJ, Aiko Y, Senju A, Kawamoto T, Hachisuga T, Araki S, Kusuhara K,

Morokuma S, Sanefuji M; Japan Environment and Children’s Study. Impact of sleep duration during pregnancy on the risk

of gestational diabetes in the Japan environmental and Children's study (JECS). BMC Pregnancy Childbirth. 2019 Dec

9;19(1):483. doi: 10.1186/s12884-019-2632-9.

Koutarou Matsumoto, Yasunobu Nohara, Yoshifumi Wakata, Takanori Yamashita, Yukio Kozuma, Rui Sugeta, Miki

Yamakawa, Fumiko Yamauchi, Eri Miyashita, Tatsuya Takezaki, Shigeo Yamashiro, Toru Nishi, Jiro Machida, Hidehisa

Soejima, Masahiro Kamouchi, Naoki Nakashima, Impact of a learning health system on acute care and medical

complications after intracerebral hemorrhage, Learning Health Systems, 10.1002/lrh2.10223, 2020.03.

Koutarou Matsumoto, Yasunobu Nohara, Hidehisa Soejima, Toshiro Yonehara, Naoki Nakashima, Masahiro Kamouchi,

Stroke prognostic scores and data-driven prediction of clinical outcomes after acute ischemic stroke, Stroke, in press,

2020.03.

Tasuku Okui, Jinsang Park, Naoki Nakashima, An Interrupted Time Series Analysis Method for Healthcare Data Using the

INGARCH Model: An Application to Psychotropic Drug Prescription Data in Japan, Asian Pacific Journal of Health

Economics and Policy, 2:2-12, 2020.02.

Jinsang Park, Tasuku Okui, Hiroko Furuhashi, Shoji Tokunaga, Naoki Nakashima, Evaluation of polypharmacy in Japan

using the national health insurance claims database in 2015-2017, European Journal of Public Health, 29(4):351, 2019.11.

Takuya Imatoh, Kimie Sai, Mayu Takeyama, Katsunori Segawa, Takanori Yamashita, Naoki Nakashima, Yoko Kataoka,

Hideto Yokoi, Tatsuo Hiramatsu, Kazuhiko Ohe, Michio Kimura, Katsuhito Hori, Junichi Kawakami, Yoshiro Saito,

Evaluating the impact of regulatory action on denosumab-induced hypocalcaemia in Japan, Journal of Clinical Pharmacy

and Therapeutics, 10.1111/jcpt.13004, 44, 5, 788-795, 2019.10.

Yasunobu Nohara, Koutarou Matsumoto, Hidehisa Soejima, Naoki Nakashima, Explanation of Machine Learning Models

Using Improved Shapley Additive Explanation, BCB '19 Proceedings of the 10th ACM International Conference on

Bioinformatics, Computational Biology and Health Informatics, 546, 2019.09.

Atsushi Kimura, Yoshihiro Matsumoto, Yoshifumi Wakata, Akiko Oyamada, Masanobu Ohishi, Toshifumi Fujiwara, Ko

Ikuta, Kuniyoshi Tsuchiya, Naohisa Tayama, Shinji Tomari, Hisaaki Miyahara, Takao Mae, Toshihiko Hara, Taichi Saito,

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Takeshi Arizono, Kozo Kaji, Taro Mawatari, Masami Fujiwara, Riku Sakimura, Kunichika Shin, Kenichi Ninomiya,

Kazutoshi Nakaie, Yasuaki Antoku, Shoji Tokunaga, Naoki Nakashima, Yukihide Iwamoto, Yasuharu Nakashima,

Predictive factors of mortality of patients with fragility hip fractures at 1 year after discharge: A multicenter, retrospective

study in the northern Kyushu district of Japan., Journal of Orthopaedic Surgery, 27(3):1–8, 2019.09.

Rafiqul Islam, Yasunobu Nohara, Md Jiaur Rahman, Nazneen Sultana, Ashir Ahmed, Naoki Nakashima, Portable Health

Clinic: An Advanced Tele-Healthcare System for Unreached Communities, Medinfo 2019, 616-619, 2019.08.

Rieko Izukura, Tadashi Kandabashi, Yoshifumi Wakata, Chinatsu Nojiri, Yasunobu Nohara, Takanori Yamashita, Atsushi

Takada, Jinsang Park, Yoshiaki Uyama, Naoki Nakashima, The Development of an Electronic Phenotyping Algorithm for

Identifying Rhabdomyolysis Patients in the MID-NET Database, Medinfo 2019, 1498-1499, 2019.08.

Jinsang Park, Takanori Yamashita, Atsushi Takada, Chinatsu Nojiri, Rieko Izukura, Yasunobu Nohara, Taeko Hotta,

Dongchon Kang, Naoki Nakashima, Effect of governance functionality for data standardization management of the

Medical Information Database Network Project, Medinfo 2019, 1562-1563, 2019.08.

Jumpei Sato, Kazuo Goda, Masaru Kitsuregawa, Naoki Nakashima, Naohiro Mitsutake, Novel Analytics Framework for

Universal Healthcare Insurance Claims Database, Medinfo 2019, 1578-1579, 2019.08.

Mitsune Yamaguchi, Satomi Inomata, Sayoko Harada, Yu Matsuzaki, Maiko Kawaguchi, Mayuko Ujibe, Mari Kishiba,

Yoshiaki Fujimura, Michio Kimura, Koichiro Murata, Naoki Nakashima, Masaharu Nakayama, Kazuhiko Ohe, Takao Orii,

Eizaburo Sueoka, Takahiro Suzuki, Hideto Yokoi, Fumitaka Takahashi, Yoshiaki Uyama, Establishment of the MID‐NET®

medical information database network as a reliable and valuable database for drug safety assessments in Japan,

Pharmacoepidemiology and Drug Safety, 10.1002, 2019.07.

Yasunobu Nohara, Rieko Izukura, Chinatsu Nojiri, Takanori Yamashita, Naoki Nakashima, Bayesian Estimation of

Prevalence of Interstitial Pneumonia by Two-sources Phenotyping Method, the 41st Annual International Engineering in

Medicine and Biology Conference (EMBC2019)

, 2019.07.

Jumpei Sato, Kazuo Goda, Masaru Kitsuregawa, Naoki Nakashima, Naohiro Mitsutake, Novel Analytics Framework for

Universal Healthcare Insurance Database, AMIA Joint Summits on Translational Science proceedings, 353–362, 2019.05.

Kaori Yamada, Maori Itoh, Yoshiaki Fujimura, Michio Kimura, Koichiro Murata, Naoki Nakashima, Masaharu Nakayama,

Kazuhiko Ohe, Takao Orii, Eizaburo Sueoka, Takahiro Suzuki, Hideto Yokoi, Chieko Ishiguro, Yoshiaki Uyama, The

utilization and challenges of Japan's MID‐NET® medical information database network in postmarketing drug safety

assessments: A summary of pilot pharmacoepidemiological studies, Pharmacoepidemiology and Drug Safety, 28(5):601-

608, 2019.05.

Naoki Nakashima, Mitsuhiko Noda, Kohjiro Ueki, Tatsuhiko Koga, Michio Hayashi, Katsuya Yamazaki, Tomoko

Nakagami, Makoto Ohara, Akira Gochi, Yasushi Matsumura, Michio Kimura, Kazuhiko Ohe, Dongchon Kang, Yoshiyuki

Toya, Kunihiro Yamagata, Koutaro Yokote, Shunya Ikeda, Naohiro Mitsutake, Ryuichi Yamamoto, Yukio Tanizawa ,

Recommended configuration for personal health records by standardized data item sets for diabetes mellitus and associated

chronic diseases: A report from Collaborative Initiative by six Japanese Associations, Journal of Diabetes Investigation,

10(3):868–875, 2019.05.

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Naoki Nakashima, Mitsuhiko Noda, Kohjiro Ueki, Tatsuhiko Koga, Michio Hayashi, Katsuya Yamazaki, Tomoko

Nakagami, Makoto Ohara, Akira Gochi, Yasushi Matsumura, Michio Kimura, Kazuhiko Ohe, Dongchon Kang, Yoshiyuki

Toya, Kunihiro Yamagata, Koutaro Yokote, Shunya Ikeda, Naohiro Mitsutake, Ryuichi Yamamoto, Yukio Tanizawa,

Recommended configuration for personal health records by standardized data item sets for diabetes mellitus and associated

chronic diseases: a report from a collaborative initiative by six Japanese associations, Diabetology International, 10(2):85–

92, 2019.04.

Y. Zhang, M. Chen, Z. Zhang, Z. Jiang, W. Shangguan, H. Einaga,, “Simultaneously catalytic decomposition of

formaldehyde and ozone over manganese cerium oxides at room temperature: Promotional effect of relative humidity on

the MnCeOx solid solution”, 327, pp. 323-333 (2019).

Y. Zhang, J. Shi, W. Fang, M. Chen, Z. Zhang, Z. Jiang, W. Shangguan, H. Einaga, “Simultaneous catalytic elimination of

formaldehyde and ozone over one-dimensional rod-like manganese dioxides at room temperature”, Journal of Chemical

Technology and Biotechnology, 94, pp. 2305-2317 (2019).

H. Guo, Z. Zhang, H. Hojo, M. Chen, H. Einaga, W. Shangguan, “Catalytic Removal of Benzene at Mild Temperature over

Manganese Oxide Catalysts”, Catal. Survey from Asia, 23, pp. 199-209 (2019).

S. Hamada, H. Hojo, H. Einaga, “Effect of Catalyst Composition and Reactor Configuration on Benzene Oxidation with a

Nonthermal Plasma-catalyst Combined Reactor”, Catal. Today, 332, pp. 144-152 (2019).

H. Guo, X. Liu, H. Hojo, X. Yao, M. Chen, H. Einaga, W. Shangguan, “Removal of benzene by Non-Thermal Plasma

catalysis over MnOx catalysts synthesized through oxalate route”, Environ. Sci. Pollution Res., 26, pp.8237-8247 (2019).

A.Tou, H.-H. Kim, H. Einaga, Y. Teramoto, A. Ogata, “Ozone-Assisted Catalysis of CO: In situ Fourier Transform

IR Evidence of the Cooperative Effect of a Bimetallic Ag-Pd Catalyst”, Chem. Eng. J., 355, pp.380-389 (2019).

K. Taira, H. Einaga, “The effect of SO2 and H2O on the interaction between Pt and TiO2(P-25) during catalytic CO

oxidation”, Catal. Lett., 149, p. 965-973 (2019).

Abe N, Yasudo H, Fukano R, Nakamura T, Okada S, Wakiguchi H, Okazaki F, Shirabe K, Toda S, Okamoto R, Ouchi K,

Ohga S, Hasegawa S:

Multi-season analyses of causative pathogens in children hospitalized with asthma.

Pediatr Allergy Immunol. 2019 Nov;30(7):724-731.

Itazawa H, Yamamoto-Hanada K, Saito-Abe M, Ayabe T, Mezawa H, Ishitsuka K, Konishi M, Nakayama SF, Michikawa

T, Senju A, Tsuji M, Kusuhara K, Sanefuji M, Ohga S, Oda M, Mitsubuchi H, Katoh T, Ikegami A, Mise N, Matsumoto K,

Saito H, Ohya Y.

Egg antigen was more abundant than mite antigen in children’s bedding: findings of the pilot study of The Japan

Environment and Children’s Study (JECS).

Allergol Int. 2019 Jul 68(3):391-393.

Kato W, Nishio M, To Y, Togashi H, Mak TW, Takada H, Ohga S, Maehama T, Suzuki A:

MOB1 regulates thymocyte egress and T cell survival in mice in a YAP1-independent manner.

Genes Cells. 2019 Jul;24(7):485-495.

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Kohara H, Utsukisawa T, Sakamoto C, Hirose L, Ogawa Y, Ogura H, Sugawara A, Aoki T, Iwasaki T, Asai T, Doisaki S,

Okuno Y, Muramatzu H, Abe T, Kurita R< Miyamoto S, Sakuma T, Shiba M, Yamamoto T, Ohga S, Yoshida K, Ogawa S,

Ito E, Kojima S, Hanno H, Tani K:

KLF1 mutation E325K induces cell cycle arrest in erythroid cells differentiated from congenital dyserythropoietic anemia

patient-specific induce pluripotent stem cells.

Exp Hematol. 2019 May;73:25-37.e8

Konishi K, Mizuochi T, Yanagi T, Watanabe Y, Ohkubo K, Ohga S, Maruyama H, Takeuchi I, Sekine Y, Masuda K, Kikuchi

N, Yotsumoto Y, Ohtsuka Y, Tanaka H, Kudo T, Noguchi A, Fuwa K, Mushiake S, Ida S, Fujishiro J, Yamashita Y, Taguchi

T, Yamamoto K:

Clinical features, molecular genetics, and long-term outcome in congenital chloride diarrhea: a nationwide study in Japan.

J Pediatr. 2019 Nov;214:151-157.e6.

Kunimura K, Sakata D, Tun X, Uruno T, Ushijima M, Katakai T, Shiraishi A, Aihara R, Kamikaseda Y, Matsubara K,

Kanegane H, Sawa S, Eberl G, Ohga S, Yoshikai Y, Fukui Y:

S100A4 Protein Is Essential for the Development of Mature Microfold Cells in Peyer’s Patches

Cell Rep. 2019 Nov 26;29(9):2823-2834.e7. doi: 10.1016/j.celrep.2019.10.091

Maezawa H, Aoki S, Nakayama SF, Niitta H, Ikeda N, Kato K, Tama S, Takekoh M, Sanefuji M, Ohga S, Oda M,

Mitsubuchi H, Senju A, Kusuhara K, Kuwajima M, Koeda T, Ohya Y, Hashimoto K:

Psychometric profile of the Ages and Stages Questionnaires, Japanese translation.

Pediatr Int. 2019 2019 Nov;61(11):1086-1095.

Matsuguma C, Wakiguchi H, Suzuki Y, Okada S, Furuta T, Ohnishi Y, Azuma Y, Ohga S, Hasegawa S:

Dynamics of Immunocyte Activation during Intravenous Immunoglobulin Treatment in Kawasaki Disease.

Scand J Rheumatol. 2019 Jul 5:1-6

Matsushita Y, Yasunari Sakai, Torio M, Inoue H, Ochiai M, Yasuoka K, Kurata H, Fujiyoshi J, Ichiyama M, Taguchi T,

Kato K, Ohga S, on behalf of the Neonatal Research Network of Japan (NRNJ):

Association of perinatal factors of epilepsy in very low birth weight infants, using a nationwide database in Japan.

J Perinatol. 2019 Nov;39(11):1472-1479.

Mizuguchi S, Motomura Y, Maki J, Baba R, Ichimiya Y, Tokuda K, Kaku N, Takada H, Maehara Y, Ohga S:

Tracheal size and morphology on the reconstructed computed tomography imaging.

Pediatr Crit Care Med. 2019 Aug;20(8):e366-e371.

Nguyen H, Kato H, Sato H, Yamaza H, Sakai Y, Ohga S, Nonaka K, Masuda K:

Positive effect of exogenous brain derived neurotrophic factor on impaired neurite development and mitochondrial function

in dopaminergic neurons derived from dental pulp stem cells from children with attention deficit hyperactivity disorder.

Biochem Biophys Res Commun. 2019 Jun 11;513(4):1048-1054.

Ochiai M, Kurata H, Inoue H, Ichiyama M, Fujiyoshi J, Watabe S, Hiroma T, Nakamura T, Ohga S:

Transcutaneous Blood Gas Monitoring among Neonatal Intensive Care Units in Japan.

Pediatr Int 2019 (in press)

Ogiwara K, Nogami K, Mizumachi K, Nakagawa T, Noda N, Ohga S, Shima M:

Page 11: 資料5 令和元年度 業績令和元年度 業績 【1】原 著 Fukushi JI, Tsushima H, Matsumoto Y, Mitoma C, Furue M, Miyahara H, Nakashima Y. Influence of dioxin-related compounds

Hemostatic assessment on the anticoagulant combination therapy with warfarin and prothrombin complex concentrates in

a case with severe protein C deficiency.

Int J Hematol. 2019 Jun;109(6):650-656

Ohnishi Y, Yasudo H, Suzuki Y, Furuta T, Matsuguma C, Azuma Y, Miyake A, Okada S, Ichihara K, Ohga S, Hasegawa S:

Clinical utility of the endothelial glycocalyx as a predictive marker of coronary artery lesions in Kawasaki disease.

Int J Cardiol. 2019 Oct 1;292:236-240.

Ohta N, Yasudo H, Mizutani M, Matsushige T, Fukano R, Kittaka S, Maehara K, Ohga S, Hasegawa S:

Serum soluble ST2 as a marker of renal scar in pediatric upper urinary tract infection.

Cytokine 2019 Aug;120:258-263

Sasazuki M, Sakai Y, Kisawa Y, Narama M, Kira R, Itai K, Toda N, Akamine S, Torio M, Ishizaki Y, Sanefuji M, Takada

H, Hara T, Ohga S:

Decision making dilemmas of pediatricians: A qualitative study in Japan.

BMJ Open. 2019 Aug 19;9(8):e026579.

Souzaki R, Kawakubo N, Matsuura T, Yoshimaru K, Koga Y, Takemoto J, Shibui Y, Kohashi K, Hayashida M, Oda Y,

Ohga S, Taguchi T:

Navigation surgery using indocyanine green fluorescent imaging for hepatoblastoma patients.

Pediatr Surg Int. 2019 May;35(5):551-557.

Taira R, Inoue H, Sawano T, Korematsu T, Fujiyoshi J, Kinjo T,Sonoda Y, Ichimiya Y, Torio M, Ishizaki Y, Sanefuji M,

Ochiai M, Sakai Y, Ohga S:

The management and outcomes of apnea in infants with trisomy 18.

Dev Med Child Neurol 2019 (in press)

Yamamura K, Sakamoto I, Morihana E, Hirata Y, Nagata H, Yamasaki Y, Okumura Y, Kohashi K, Koto K, Tsutsui H, Ohga

S:

Elevated non-invasive liver fibrosis markers and risk of liver carcinoma in adult patients after repair of tetralogy of Fallot.

Int J Cardiol. 2019 Jul 15;287:121-126

Yanagisawa R, Matsuda K, Ohga S, Kanegane H, Morimoto A, Saito AM, Horibe K, Ishii E, Nakazawa Y:

Factors predicting the recurrence of pediatric Epstein–Barr virus-associated hemophagocytic lymphohistiocytosis after

treatment under the HLH-2004 protocol.

Int J Hematol. 2019 May;109(5):612-617.

Yanagisawa R, Nakazawa Y, Matsuda K, Yasumi T, Kanegane H, Ohga S, Morimoto A, Saito AM, Horibe K, Ishii E, and

HLH/LCH committee members of the Japan Children’s Cancer Group.Outcomes of children with hemophagocytic

lymphohistiocytosis treated using HLH-2004 protocol in Japan.

Int J Hematol. 2019 Feb;109(2):206-213.

Yasuoka K, Inoue H, Ochiai M, Tanaka K, Kurata H, Fujiyoshi J, Matsushita Y, Suga S, Ohkubo K, Sakai Y, Ohga S, on

behalf of the Neonatal Research Network of Japan:

Late-onset circulatory collapse and risk of cerebral palsy in extremely preterm infants.

J Pediatr. 2019 Sep;212:117-123.e4.

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Sonoda M, Ishimura M, Eguchi K, Shiraishi A, Kanno S, Kaku N, Inoue H, Motomura Y, Ochiai M, Sakai Y, Nakayama

M, Ohara O, Ohga S:

Prognostic factors for survival of herpes simplex virus-associated hemophagocytic lymphohistiocytosis.

Int J Hematol. Published online: Sep 23, 2019

Etsuro Nanishi, Takayuki Hoshina, Masafumi Sanefuji, Ryo Kadoya, Katsuhiko Kitazawa, Yukie Arahata, Tetsuya Sato,

Yoshimichi Hirayama, Katsuki Hirai, Masaaki Yanai, Kaori Nikaido, Akihiko Maeda, Hiroyuki Torisu, Kenji Okada,

Yasunari Sakai, Shouichi Ohga:

A Nationwide Survey of Pediatric-onset Japanese Encephalitis in Japan.

Clinical Infectious Diseases 2019;68(12):2099-104

Fujiyoshi J, Yamaza H, Sonoda S, Yuniartha R, Ihara K, Nonaka K, Taguchi T, Ohga S, Yamaza T:

Therapeutic potential of hepatocyte-like-cells converted from stem cells from human exfoliated deciduous teeth in

fulminant Wilson's disease.

Sci Rep. 2019 Feb 7; 9(1): 1535.

Ichiyama M, Inoue H, Ochiai M, Ishimura M, Shiraishi A, Fujiyoshi J, Yamashita H, Sato K, Matsumoto S, Hotta T,

Uchiumi T, Kang D, Ohga S:

Diagnostic challenge of the newborn patients with heritable protein C deficiency.

J Perinatol. 2019 Feb; 39(2): 212-219.

Iwasawa S, Yanagi K, Kikuchi A, Kobayashi Y, Haginoya K, Matsumoto H, Kurosawa K, Ochiai M, Sakai Y, Fujita A,

Miyake N, Niihori T, Shirota M, Funayama R, Nonoyama S, Ohga S, Kawame H, Nakayama K, Aoki Y, Matsumoto N,

Kaname T, Matsubara Y, Shoji W, Kure S:

Recurrent de novo MAPK8IP3 variants cause neurological phenotypes.

Ann Neurol. 2019 Jun; 85(6): 927-933.

Kawakubo N, Kinoshita Y, Souzaki R, Koga Y, Oba U, Ohga S, Taguchi T:

The Influence of Sarcopenia on High-Risk Neuroblastoma.

J Surg Res 236:101-105, 2019

Kinjo T, Inoue H, Kusuda T, Fujiyoshi J, Ochiai M, Takahata Y, Honjo S, Koga Y, Hara T, Ohga S:

Chemokine levels predict progressive liver disease in Down syndrome patients with transient abnormal myelopoiesis.

Pediatr Neonatol. 2019 Aug; 60(4): 382-388.

Kinoshita K, Ishizaki Y, Yamamoto H, Sonoda M, Yonemoto K, Kira R, Sanefuji M, Ueda A, Matsui H, Ando Y, Sakai Y,

Ohga S:

De novo p.G696S mutation in COL4A1 causes intracranial calcification and late-onset cerebral hemorrhage: A case report

and review of the literature.

Eur J Med Genet 2019 (in press)

Kudo K, Maeda M, Suzuki N, Kanegane H, Ohga S, Ishii E, Shioda Y, Imamura T, Imashuku S, Tsunematsu Y, Endo M,

Shimada A, Koga Y, Hashii Y, Noguchi M, Inoue M, Tabuchi K, Morimoto A:

Nationwide retrospective review of hematopoietic stem cell transplantation in children with refractory Langerhans cell

histiocytosis.

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Int J Hematol 2019, in press

Kurata H, Ochiai M, Inoue H, Kusuda T, Fujiyoshi J, Ichiyama M, Wakata Y, Takada H:

Inflammation in the neonatal period and intrauterine growth restriction aggravate bronchopulmonary dysplasia.

Pediatr Neonatol. 60(5):496-503, 2019

Nagata H, Terashi E, Muraoka M, Uike K, Hirata Y, Tatewaki H, Fujita Y, Yamamura K, Ohga S:

High incidence of ductal closure or narrowing at birth in patients with right ventricular outflow tract obstruction with

normal orientation of the ductus arteriosus.

Cardiol Young 29(1):54-58, 2019

Nakashima Y, Nanishi E, Yamamura K, Uike K, Terashi E, Hirata Y, Nagata H, Morihana E, Tanaka T, Honjo S, Takada H,

Ohga S:

Procalcitonin levels predicting the infliximab response of immunoglobulin resistant Kawasaki disease.

Cytokine 114:26-31, 2019

Nanishi E, Hoshina T, Sanefuji M, Kadoya R, Kitazawa K, Arahata Y, Sato T, Hirayama Y, Hirai K, Yanai M, Nikaido K,

Maeda A, Torisu H, Okada K, Sakai Y, Ohga S:

A nationwide survey of pediatric-onset Japanese encephalitis in Japan.

Clin Infect Dis 2019; 68: 2099-2104.

Tanaka M, Sanefuji M, Morokuma S, Yoden M, Momoda R, Sonomoto K, Ogawa M, Kato K, Nakayama J:

The association between gut microbiota development and maturation of intestinal bile acid metabolism in the first 3 y of

healthy Japanese infants.

Gut Microbes, 2019 (in press)

Tsuji M, Shibata E, Askew DJ, Morokuma S, Aiko Y, Senju A, Araki S, Sanefuji M, Ishihara Y, Tanaka R, Kusuhara K,

Kawamoto T, Japan Environment and Children’s Study Group:

Associations between metal concentrations in whole blood and placenta previa and placenta accreta: the Japan Environment

and Children's Study (JECS).

Environ Health Prev Med. 24(1):40, 2019.

小野寺 武、枝田拓也、園田英人、松井利郎、都甲 潔:表面プラズモン共鳴センサを用いた尿中カテコア

ミン代謝物の検出. 電気学会論文誌E(センサ・マイクロマシン部門誌), 139(9), 278-282 (2019).

城戸 咲、日高 庸博、甲斐 翔太朗、中野 嵩大、蜂須賀 正紘、藤田 恭之、加藤 聖子:SLE 女性における妊

娠中の原疾患増悪および妊娠高血圧腎症の合併に関連する妊娠時所見の検討.日本周産期・新生児医学会雑誌.

55(1):92-7, 2019

甲斐 翔太朗、坂井 淳彦、中野 嵩大、城戸 咲、蜂須賀 正紘、日高 庸博、加藤 聖子:Cesarean hysterectomy

における両側総腸骨動脈バルーン閉塞術の有効性と合併症.日本周産期・新生児医学会雑誌. 55(1):108-13,

2019

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【2】総 説

Furue M, Hashimoto-Hachiya A, Tsuji G. Aryl Hydrocarbon Receptor in Atopic Dermatitis and Psoriasis. Int J Mol Sci.

2019 Oct 31;20(21):5424.

Peng F, Tsuji G, Zhang JZ, Chen Z, Furue M. Potential role of PM<sub>2.5</sub> in melanogenesis. Environ Int. 2019

Nov;132:105063.

Yoshinori Mine, Toshiro Matsui: Current understanding of bioaccessibility and bioavailability of food-derived bioactive

peptides. Int. J. Food Sci. Technol., 54(7), 2319-2320 (2019).

Weilin Shen, Toshiro Matsui: Intestinal absorption of small peptides: A review. Int. J. Food Sci. Technol., 54(6), 1942-

1948 (2019).

Huu-Nghi Nguyen, Tae Hun Ham, Toshiro Matsui, Mitsuru Tanaka: Detection and Visualization of Food-Derived

Polyphenols by Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging. Sensors and Materials, 31(7),

2333-2346 (2019).

Sudo, N

Role of gut microbiota in brain function and stress-related pathology

BIOSCIENCE OF MICROBIOTA FOOD AND HEALTH 38 : 75-80 . 2019

Ninomiya T, et al. Epidemiological Evidence of the Relationship Between Diabetes and Dementia.

Adv Exp Med Biol. 2019;1128:13-25

Komatsu T, Park S, Hayashi H, Mori R, Yamaza H, Shimokawa I. Mechanisms of Calorie Restriction: A Review of

Genes Required for the Life-Extending and Tumor-Inhibiting Effects of Calorie Restriction. Nutrients. 11(12):3068, 2019.

Taguchi T, Yanagi Y, Yoshimaru K, Zhang XY, Matsuura T, Nakayama K, Kobayashi E, Yamaza H, Nonaka K, Ohga S,

Yamaza T. Regenerative medicine using stem cells from human exfoliated deciduous teeth (SHED): a promising new

treatment in pediatric surgery. Surg Today. 49(4):316-322, 2019.

Taguchi T, Yanagi Y, Yoshimaru K, Zhang XY, Matsuura T, Nakayama K, Kobayashi E, Yamaza H, Nonaka K, Ohga S,

Yamaza T:

Development of New Treatment in Pediatric Surgery -Regenerative Medicine using Stem Cells from Human Exfoliated

Deciduous Teeth (SHED)-

Surgery Today 2019

松井利郎

高血圧予防に関わる醤油由来低分子ペプチド. 醤油の研究と技術, 45(4), 223-228 (2019).

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松井利郎

食科学研究と MALDI-MS およびイメージング法の接点. 一財)食品分析開発センター

SUNATEC e-magazine 11 月号メールマガジン vol. 164 (2019).

咸 兌勳、松井利郎、田中 充

MALDI-MS イメージング法による食品成分の腸管吸収過程の可視化.

食加工技術, 39(3), 100-108 (2019).

諸隈誠一

大気汚染の周産期への影響について

日本医事新報 4992 号 P.63 2019 年 12 月 28 日

中島直樹

健康医療情報のデータ 2 次利用の影と対策, 新医療, 20-24, 2020.03.

中島直樹

医療の ICT 化と AI, 総合リハビリテーション, 48(1):13-18, 2020.01.

中島直樹

遠隔医療の現状と今後の期待, JOHNS, 35(10):1417-1421, 2019.10.

中島直樹

医療の ICT 化と精神科領域, 臨床精神医学, 48(9):1021-1027, 2019.09.

中島直樹

蓄積した医療データの 2 次活用における Phenotyping の重要性, 臨床病理, 67(7):719-727, 2019.07.

中島直樹

次世代医療基盤法と糖尿病, 糖尿病 医師・医療スタッフのプラクティス, 36(3):311-316, 2019.05.

中島直樹

糖尿病とビッグデータ, Precision Medicine, 2(5):10-13, 2019.05.

永長久寛

「オゾンを酸化剤とした触媒酸化技術の原理と応用」、フジコー技報「創る」、27, pp.17-21 (2019).

西山慶

腎移植の現況 小児腎移植の現況

Page 16: 資料5 令和元年度 業績令和元年度 業績 【1】原 著 Fukushi JI, Tsushima H, Matsumoto Y, Mitoma C, Furue M, Miyahara H, Nakashima Y. Influence of dioxin-related compounds

腎と透析 87(1):18-24, 2019

Ⅸ.低身長を伴う遺伝性(先天性)症候群 7.Fanconi 貧血

江口 克秀、石井 加奈子、石村 匡崇、大賀 正一

内分泌症候群(第3版) Ⅳ—その他の内分泌疾患を含めて— p.430-434

井上普介、落合正行、酒井康成:

成育限界児の生命予後と神経学的予後~長期予後の改善が次の目標である~

日本医事新報 2019; 4981: 56.

園田 素史、石村 匡崇、市山 正子、藤吉 順子、井上 普介、落合 正行、大賀 正一

新生児単純ヘルペスウイルス関連血球貪食性リンパ組織球症(HSV-HLH)

日本産婦人科・新生児血液学会誌 28(2): 63-70, 2019

江口克秀、石村匡崇、大賀正一

特集/発達・加齢と血液疾患

7.小児の EB ウイルス関連血液疾患の病態生理

血液内科 第 79 巻第 3 号(2019 年 9 月)p.309-314

江口克秀、石村匡崇、白石暁、大賀正一

特集:小児科医に必要な免疫の知識

6.腫瘍・血液疾患 1)リンパ増殖性疾患

小児内科 51 巻 8 号(2019 年 8 月号)p.1191-1195"

神野俊介、大賀正一

予防接種の実際-麻疹・風疹・おたふくかぜ

臨牀と研究 96(2):157-62, 2019

西山慶、本村良知、白石暁、大賀正一

各科におけるステロイド療法のノウハウ 小児科

臨床と研究 96(4) 447-456, 2019

石村匡崇、大賀正一

先天性骨髄不全症候群と原発性免疫不全症におけるがん素因

臨床血液 60 (6) p. 702-707, 2019

大賀正一、長尾哲彦

内科外来における子供の診かた

Page 17: 資料5 令和元年度 業績令和元年度 業績 【1】原 著 Fukushi JI, Tsushima H, Matsumoto Y, Mitoma C, Furue M, Miyahara H, Nakashima Y. Influence of dioxin-related compounds

臨床と研究 96(9) 1087-1093

大賀正一

こどもの診かた-新生児と乳幼児

臨床と研究 96(9) 997-1002

大賀正一

特集 新生児・小児の血栓症と DIC 小児科領域の血栓症

Thrombosis Medicine 9(2) 5-10

白石暁、園田素史、大賀正一

遺伝性炎症性腸疾患

日本医事新報「差分解説」

白石暁、石村匡崇、大賀正一

小児科診療ガイドライン 第4版 11. 免疫・膠原病 先天性免疫不全症候群

落合正行、井上普介、大賀正一

新生児と小児における臨床検査のピットフォール

臨床病理 2019; 67: 253-258.

落合正行、大賀正一

血栓止血学の新知見 3.新生児の血栓症

日本新生児成育医学会雑誌 2020; 31(2) (in press)

落合正行

NICU 便り

あかちゃん成育ネットワーク会報(2019 年 3 月号)

落合正行

非侵襲的陽圧換気(Non-invasive positive pressure ventilation)における経皮ガスモニタリングの有効性

Radiometer QA Journal(2018 年 12 月号)

城戸咲、加藤聖子

SLE の増悪

Ⅲ.産科編 妊産褥婦の合併疾患への対処法 内分泌・自己免疫疾患

臨床婦人科産科. 73(4)増刊号: 318-23, 2019

Page 18: 資料5 令和元年度 業績令和元年度 業績 【1】原 著 Fukushi JI, Tsushima H, Matsumoto Y, Mitoma C, Furue M, Miyahara H, Nakashima Y. Influence of dioxin-related compounds

【3】著 書

Shinobu Yasuo, Chrononutritional modulation of sleep and the circadian clock by amino acids. In: Neurological

Modulation of Sleep: Mechanisms and Functions in Sleep Health, Second Edition, Elsevier, 375-383, 2020

日高庸博、加藤聖子:D.3 産褥期の精神障害

産科婦人科疾患最新の治療 2019-2021. 119-21, 2019

落合正行

早産児の貧血

今日の治療指針 2020 年版-私はこう治療している(2020 年 1 月)

【4】症例報告

Kitadai Y, Kan N, Tsukimori K. A rare association of left pulmonary artery sling with right pulmonary hypoplasia and total

anomalous pulmonary venous connection. Cardiol Young. 29(4):538-540, 2019

Tsukimori K, Kitadai Y, Kan N. Prenatal Diagnosis of Criss-Cross Heart Using 4-Dimensional Color Doppler Rendering.

Pediatr Cardiol. 40(1):237-239, 2019.

Imachi Y, Hidaka N, Kai S, Hachisuga M, Kato K:Prolongation of Second Twin's Delivery Until Term : A Rare Case of

Delayed-Interval Delivery. Clin Med Res. 17(1-2): 37-40, 2019

Oga S, Hachisuga M, Hidaka N, Fujita Y, Tomonobe H, Yamamoto H, Kato K:Gastric cancer during pregnancy with

placental involvement: case report and review of published works. Obstet Gynecol Sci. 62(5): 357-61, 2019

Kobayashi Y, Nakano T, Hidaka N, Kato K:A rare case of fetal meconium peritonitis developing. coagulopathy in utero.

J Med Ultrasound. 27(4):205-7, 2019

Kai S, Fujita Y, Sato Y, Kido S, Hidaka N, Sakamoto I, Kato K:Pregnancy managed by unfractionated heparin after

mechanical aortic valve replacement. J Matern Fetal Neonatal Med. 33(6):1030-2, 2020

Sonoda Y, Yamamura K, Ishii K, Ohkubo K, Ihara K, Sakai Y, Ohga S:

A Child with Prostaglandin I2-associated Thyrotoxicosis: Case Report.

J Clin Res Pediatr Endocrinol 11(2):207-210, 2019

Takemoto R, Motomura Y, Kaku N, Ichimiya Y, Muraoka M, Kanno S, Tanaka T, Sakai Y, Maehara Y, Ohga S:

Late-onset sepsis and encephalopathy after bicycle-spoke injury: a case report.

Page 19: 資料5 令和元年度 業績令和元年度 業績 【1】原 著 Fukushi JI, Tsushima H, Matsumoto Y, Mitoma C, Furue M, Miyahara H, Nakashima Y. Influence of dioxin-related compounds

BMC Infect Dis. 28: 472, 2019

Hagio Y, Shiraishi A, Ishimura M, Sonoda M, Eguchi K, Yamamoto H, Oda Y, Ohga S:

Posttransplant recipient-derived CD4+ T-cell lymphoproliferative disease in X-linked hyper-IgM syndrome.

Pediatr Blood Cancer. 2019 Mar;66(3):e27529. doi: 10.1002/pbc.27529.

Hamano H, Matsushige T,Inoue H, Hoshide M, Oka M,Kouno F, Ichiyama T, Ohga S, Ouchi K, Hasegawa S:

A case of acute encephalophathy with residual neurological sequelae induced by immunoglobulin A vasculitis.

J Clin Neurosci. 2019 Sep;67:270-271. doi: 10.1016/j.jocn.2019.05.061.

Ichimiya Y, Sonoda M, Ishimura M, Kanno S, Ohga S:

Hemorrhagic Pneumonia as the First Manifestation of Anhidrotic Ectodermal Dysplasia with Immunodeficiency.

J Clin Immunol 39(3):264-66, 2019

Iida Y, Fukano R, Yasudo H, Azuma Y, Ichimura T, Ohga S, Hasegawa S:

The surge of serum Interleukin-2 level in a Japanese patient with cytarabine syndrome.

Pediatr Blood Cancer 2019 letter

Ishimura M, Eguchi K, Shiraishi A, Sonoda M, Azuma Y, Yamamoto H, Imadome K, Ohga S:

Systemic Epstein-Barr virus-positive T/NK lymphoproliferative diseases with SH2D1A/XIAP hypomorphic gene variants

Front Pediatr. 2019; 7: 183. doi: 10.3389/fped.2019.00183

Ochiai M, Nagata H, Tanaka K, Ihara K, Ohga S:

Critical association of Pallister-Hall syndrome and congenital heart disease

Pediatr Int. 2019 Aug; 61(8): 827-828.

Okuzono S, Fukai R, Noda M, Miyake N, Lee S, Kaku N, Sanefuji M, Akamine S, Kanno S, Ishizaki Y, Torisu H, Kira R,

Matsumoto N, Sakai Y, Ohga S:

An acute encephalopathy with reduced diffusion in BRAF-associated cardio-facio-cutaneous syndrome.

Brain Dev 41(4):378-381, 2019

Takemoto R, Motomura Y, Kaku N, Ichimiya Y, Muraoka M, Kanno S, Tanaka T, Sakai Y, Maehara Y, Ohga S:

Late-onset sepsis and encephalopathy after bicycle-spoke injury: a case report.

BMC Infect Dis 19(1):472, 2019

Tanita K, Hoshino A, Imadome KI, Kamiya T, Inoue K, Okano T, Yeh TW, Yanagimachi M, Shiraishi A, Ishimura M,

Schober T, Rohlfs M, Takagi M, Imai K, Takada H, Ohga S, Klein C, Morio T, Kanegane H:

Epstein-Barr Virus-Associated γδ T-Cell Lymphoproliferative Disorder Associated With Hypomorphic IL2RG Mutation.

Page 20: 資料5 令和元年度 業績令和元年度 業績 【1】原 著 Fukushi JI, Tsushima H, Matsumoto Y, Mitoma C, Furue M, Miyahara H, Nakashima Y. Influence of dioxin-related compounds

Front Pediatr. 2019; 7:15. doi: 10.3389/fped.2019.00015.

Yonemoto K, Ichimiya Y, Sanefuji M, Kaku N, Sakata A, Baba R, Yamashita F, Akamine S, Torio M, Ishizaki Y, Maehara

Y, Sakai Y, Ohga S:

Early intervention with adrenocorticotropin for acute encephalopathy-associated epileptic spasms: Report of two cases.

Clin EEG Neurosci 50:51-55, 2019