液相層析質譜分析 LC-MS Method development and Analyte Identification 授課教師:賴滄海教授 授課教師:賴滄海教授03-12-2008.
Drug abuse prevention and treatment 授課教師:賴滄海教授 1-8-2010.
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Transcript of Drug abuse prevention and treatment 授課教師:賴滄海教授 1-8-2010.
Learning Objectives
Major types of drug prevention program Levels of prevention program Alternatives to drug use Principles that characterized effective drug treatment Pharmacological strategies to treat addiction
Potential Factors that Influence
Potential Factors that Influence Drug Use
Individual influence Genetics, Personality traits, Attitudes and beliefs, peer resistance skills 。Interpersonal and societal influences Parents, Community, Peers, School policy, Local law enforce
ment, Personal situation
Potential Factors that Influence Drug Use
Environmental influences Federal laws, Minimum purchase age, Portrayal of alcohol, tobacco and drugs on
TV and movies, Marketing of alcohol, Cost of alcohol and drugs
Primary Prevention Program (Risk reduction before abuse)
Interpersonal factors Affective education (emotional literacy), Values clarification Resilience training Assertiveness training Refusal skill Drug information and education
Primary Prevention Program
Small group factors
Peer mentoring, counseling
Conflict resolution
Demonstrate misconception of peer norm
Alternatives to drug use
recreational, cultural, athletic
Strengthening families
Primary Prevention Program
Systems level
Strengthening school-family link
Strengthening school-community group links
Strengthening community support system
Media advocacy efforts
Reducing alcohol marketing
Secondary Prevention Program
Intervening in early abuse
Identification of abuse subgroups and
individual diagnosis
Early intervention coupled with sanction
Teacher-counselor-parent team approach
Developing healthy alternative youth culture
Recovering role model
Tertiary Prevention Program
Intervening in advanced abuse Assessment and diagnosis Referral into treatment Case management Reentry
Common school-based drug prevention approaches
Cognitive
Teach pharmacology of drugs
How they are used
Long-range consequences of use
(usually through scare tactics)
Common school-based drug prevention approaches
Affective
Raise self-esteem
Teach value and life skill
(typically do not include drug information)
Common school-based drug prevention approaches
Combined cognitive and affective
Teach problem solving, decision making, peer pressure resistance skill
Provide drug information to connect life skill and drug use and consequences
Common school-based drug prevention approaches
Social learning
Teach how to identify pressure from peers, media, advertising families
Teach resistance skills, counterargument
Student role play and practice resisting
Common school-based drug prevention approaches
Normative education
Correct misconceptions
Demonstrate actual norms through discussion, develop nonuse norms
Curriculum based drug education objectives- Elementary level
Drugs vs poison, effect of ATOD on the body Candy vs drug, drug overdose How to say NO Reason for taking drugs
Curriculum based drug education objectives- Junior high level
How peer pressure works, how to say NO How drugs affect the body Where to seek help Attitude toward drug use How to have fun without drug Harmful effect of ATOD
Curriculum based drug education objectives- Junior high level
Stress management, positive self-esteem How advertisers push drug Consequences of breaking drug laws Wine, beer and distilled spirits Family drug use violence and drug use in concerts Teenage drug use and associated problems
Curriculum based drug education objectives- Senior high level
Responsible use of medication How drug affect the body Legal vs illegal drugs Drinking, drug and driving Recreational drug use Stress management
Curriculum based drug education objectives- Senior high level
How to detect problem drug users Drug education, prevention and treatment Positive, negative role models How to build positive self-esteem Binge drinking, date rape Drug addiction and alcoholism Criminal sanction for drug use
Drug prevention in higher education
Awareness only model
Assumes that teaching about the harmful effects of drugs will change attitudes about use and abuse
Attitude change model
Assumes that people use drugs because of lack of self-esteem
Drug prevention in higher education
Social influence model
Assumes that drug users lack resistance skills
Person-in environment model
Stress that changes in the environment change people’s attitude about drugs
Family-based prevention program
Risks factors
Chaotic home environment
Ineffective parenting
Lack of mutual attachment and nurturing
Family-based prevention program
Protective factors
Strong parent-child bonds
Clear rules of conduct
Communication of values
High level of supervision
Parental warmth, affection and support
Family-based prevention program
Reach families of children at each stage Train parents in behavior skills to
reduce conduct problems in children
Improve parent-child relation
Consistent discipline and rule making
Monitor children’s activities
Family-based prevention program
Drug information for parent and children Enhance protective factors Provide access to counseling services for
families at risk
Drug prevention programs in USA
The BACCHUS network 2005 BACCHUS and GAMMA peer education
network 1975
Boosting Alcohol Consciousness Concerning the Health of University Students
Greeks Advocating Mature Management of Alcohol
Drug prevention programs in USA
FIPSE 1987 Fund for the Improvement of Postsecondary
Education Drug Prevention Program Peer-based effort Curriculum infusion Improvisational theater group Strategies to change misconception of use Alternative events Change marketing of alcohol near campus
Drug prevention programs in USA
DARE 1983 Drug Abuse Resistance Education Presented in the classroom by uniformed police officers Drug Courts 1989 To divert substance abuser into supervised
community treatment centers to eliminate the destructive behaviors.
Alternatives for a drug abuser
Physical
Athletics, exercise, hiking
Dance, yoga
Carpentry, swimming
Outdoor work
Alternatives for a drug abuser
Sensory
Sensory awareness training
Sky diving, scuba diving
Experiencing beauty of nature
Alternatives for a drug abuser
Emotional
Individual counseling
Group therapy
Instruction in psychology of personal development
Alternatives for a drug abuser
Interpersonal
Group therapy
Instruction in social custom
Confidence training
Volunteerism
Alternatives for a drug abuser
Social
Activity in positive social change
Helping the disadvantaged
Tutoring handicapped individuals
Ecology action
Alternatives for a drug abuser
Political
Political service
Lobbying for nonpartisan projects
Field work with politician and public officials
Alternatives for a drug abuser
Intellectual
Reading, debate and discussion
Creative games and puzzle
Self-hypnotics
Training in concentration
Alternatives for a drug abuser
Creative-aesthetics
Nongraded instruction in producing/or
appreciation art, music, drama
Creative hobbies
Alternatives for a drug abuser
Philosophical
Discussions, seminar
Courses on ethics
The nature of reality
Relevant philosophical literature
Exploration of value systems
Alternatives for a drug abuser
Spiritual-mystical
Nonchemical methods of spiritual development
Study of world religions Mysticism Meditation, yogic techniques
Principles of treatment
No single treatment is appropriate
for all individuals Treatment needs to be readily available Attends to multiple needs of the
individual
Principles of treatment
Must be assessed continually and modified
as necessary Remaining in treatment for an appropriate
period is critical Counseling and behavioral therapy are
critical component
Principles of treatment
Medications are an important element of treatment
Addicted individual with coexisting mental disorder should have both treated
Treatment does not need to be voluntary Medical detoxification is only the first step
Principles of treatment
Possible drug use during treatment must be monitored continuously
Should provide assessment for infectious disease
Recovery can be a long-term process
Detoxification-Sedative/hypnotics
*Substitution with longer-acting barbiturates for shorter acting CNS depressant – (abrupt withdrawal may cause life-threatening seizure)
*Gradually reduce the longer-acting barbiturates
*To treat Alcohol and barbiturate- need increased dose
*To treat barbiturate and heroin- barbiturate first
Detoxification-Alcohol
Delirium tremens Phenobarbital, Librium and Diazepam are commonly
prescribed to prevent withdrawal symptoms Treatment for malnutrition and Vit. Deficiency Diasulfiram – blocks ethanol metabolism, resulting in
headache, flushing and nausea Acamprosate – maintaining abstinence of alcohol
Detoxification-Heroin
Clonidine (Catapres) to relieve some withdrawal effects (vomiting, diarrhea)
Substitution with methadone, buprenorphine for heroin
Counseling to modify drug seeking behavior
Treatment- Amphetamines
Behavior intervention to modify thinking pattern, improve cognitive skill, change expectation, increase coping
with life’s stress
Detoxification- Cocaine
Outpatient versus Inpatient Benzodiazepines to relieve anxiety Bromocriptine, levodopa to relieve craving Desipramine and imipramine to relieve depre
ssion and craving Counseling, support from family, friends and
coworkers
Twelve steps by AA
1. We admitted we were powerless over alcohol-that our lives had become unmanageable
2. Came to believe that a Power greater than ourselves could restore us to sanity
3. Made a decision to turn our will and our lives to the care of God as we understood Him
Twelve steps by AA
4. Made a searching and fearless moral inventory of ourselves
5. Admitted to God, to ourselves, and to another human being the exact nature of our wrongs
6. Were entirely ready to have God remove all these defects of character
Twelve steps by AA
7. Humbly asked Him to remove our shortcomings 8. Made a list of all persons we had harmed, and became willing to make amend to them all
Twelve steps by AA
9. Made direct amends to such people wherever possible, except when to do so would injure them or others
10. Continued to take personal inventory and when we were wrong promptly admitted it
Twelve steps by AA
11. Sought through prayer and meditation to improve our conscious contact with God as we understood Him, praying only for knowledge of His will for us and the power to carry that out
12. Having had a spiritual awakening as the result of these step, we tried to carry this message to alcoholics, and to practice these principles in all our affairs