Ceftriaxone Omeprazole Ipatropium Salbutamol Aspirin

8/17/2019 Ceftriaxone Omeprazole Ipatropium Salbutamol Aspirin

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DRUG

ORDER

PHARMACOLOGIC ACTION

OF DRUG

INDICATIONS AND

CONTRAINDICATION

ADVERSE EFFECT OF

THE DRUG

DESIRED ACTIO

ON THE CLIEN


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Ceftriaxo

ne

Ceftriaxone inhibits the

snthesis in the ba!teria"

!e"" #a""$ Li%e other

!e&ha"os&orins of the

'thir( )eneration'* it has

a +er broa( anti,

ba!teria" -anti,.i!robia"/0

s&e!tr1. an( it is stab"e

a)ainst .ost 2,

"a!ta.ases$ Ceftriaxone

is hi)h" e3!ient a)ainst

stre&to!o!!i*

Hae.o&hi"1s in41en5ae*

neisseriae* &eni!i""in

resistant strains of

Sta&h"o!o!!1s a1re1s*

.1"tiresistant

enteroba!ters* as #e"" as

other ba!teria$ Its e6e!t

a)ainst Pse1(ono.as

aer1)inosa is "i.ite( an(

it is ine6e!ti+e a)ainst

.ethi!i""in resistant

strains of Sta&h"o!o!!1s

a1re1s* Entero!o!!1s

fae!a"is* C"ostri(i1.

(i3!i"e* an( 7a!teroi(es

fra)i"is$

Indications:

• Perio&erati+e

&ro&h"axis

• Treat.ent of8

9 Res&irator tra!tinfe!tions9 S%in an( s%in

str1!t1re infe!tions9 7one an( :ointinfe!tions9 Urinar tra!t an()ne!o"o)i!infe!tion9 Se&ti!e.ia

Contraindications: H&ersensiti+it to

!e&ha"os&orins

Serio1s

h&ersensiti+it

to &eni!i""ins

CNS: sei51res -hi)h

(oses0$

Gastrointestinal:

&se1(o.e.brano1

s !o"itis* (iarrhea*

na1sea* +o.itin)*

!ra.&s* &se1(o"ithiasis

Dermatologic:

rashes* 1rti!aria$

Hematologic:

b"ee(in)* b"oo(

(s!rasias*

he.o"ti! ane.ia$

Local: &ain at IMsite* &h"ebitisat IV

site$

• Miscellaneous:

a""er)i! rea!tions

in!"1(in)

ana&h"axis an(

ser1. si!%ness*

s1&erinfe!tion$

• For treatin)

&atient;s

&ne1.onia

an(

in4a..atio

of bron!hio"e

(1e to

asth.a


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NURSING RESPONSI7ILITES AND CAUTIONS

• Assess &atient for infe!tion -+ita" si)ns< a&&earan!e of #o1n(* s&1t1.* 1rine* an( stoo"< =7C0 at

be)innin) of an( thro1)ho1t thera&

• 7efore initiatin) thera&* obtain a histor to (eter.ine &re+io1s 1se of an( rea!tions to &eni!i""ins or

!e&ha"os&orins$ Persons #ith a ne)ati+e histor of &eni!i""in sensiti+it .a sti"" ha+e an a""er)i!

res&onse

• Obser+e &atient for si)ns an( s.&to.s of ana&h"axis -rash* &r1rit1s* "arn)ea" e(e.a* #hee5in)0$

Dis!ontin1e the (r1) an( notif the &hsi!ian or other hea"th !are &rofessiona" i..e(iate" if these

s.&to.s o!!1r$ >ee& e&ine&hrine* an antihista.ine* an( res1s!itation e?1i&.ent !"ose b in the e+en

of an ana&h"a!ti! rea!tion

• Ma !a1se in!rease( ser1. AST* ALT* a"%a"ine &hos&hatase* bi"ir1bin* LDH* 7UN* an( !reatinine

• Ma rare" !a1se "e1%o&enia* ne1tro&enia* a)ran1"o!tosis* thro.bo!to&enia* eosino&hi"ia*

".&ho!tosis* an( thro.bo!tosis

• Monitor in:e!tion site fre?1ent" for &h"ebitis -&ain* re(ness* s#e""in)0$ Chan)e sites e+er @B hr to

&re+ent &h"ebitis• In:e!t (ee& into a #e"",(e+e"o&e( .1s!"e .ass< .assa)e #e""

• A(+ise &atient to re&ort si)ns of s1&erinfe!tion -f1rr o+er)ro#th on the ton)1e* +a)ina" it!hin) or

(is!har)e* "oose or fo1",s.e""in) stoo"s0 an( a""er)

• Instr1!t &atient to notif hea"th !are &rofessiona" if fe+er an( (iarrhea (e+e"o&* es&e!ia"" if stoo" !ontain

b"oo(* &1s* or .1!1s$ A(+ise &atient not to treat (iarrhea #itho1t !ons1"tin) hea"th !are &rofessiona"$

• =at!h o1t for &ossib"e (r1),(r1) intera!tions8

Probenecid (e!reases ex!retion an( in!reases b"oo( "e+e"s

If alcohol is in)este( #ithin @B hr of !efa.an(o"e* !ef.eta5o"e* or !efotetan* a (is1"ra.,"i%


4/12

rea!tion .a o!!1r

Cefa.an(o"e* !ef.eta5o"e* an( !efotetan .a &otentiate the e6e!ts of anticoagulants an(

in!rease the ris% of b"ee(in) #ith antiplatelet agents* thrombolytics* NSAIDs* plicamycin* oalproic acid$

DRUG

ORDER


OF DRUG

INDICATIONS AND

CONTRAINDICATION

ADVERSE EFFECT OF

THE DRUG

DESIRED ACTIO

ON THE CLIEN


5/12

O.e&ra5o"

e @.)

tab* tab

o( &o

!her" Class: anti1"!er

a)ents

Pharm" Class: &roton

&1.& inhibitors

7in(s to an en5.e on

)astri! &arieta" !e""s in the

&resen!e of a!i(i! )astri!

&H* &re+entin) the na"

trans&ort of h(ro)en ions

into the )astri! "1.en

Thera&e1ti! E6e!ts8

9 Di.inishe(

a!!1.1"ation of a!i( in the

)astri! "1.en #ith"essene( )astroeso&ha)ea"

re41x

9 Hea"in) of (1o(ena"

1"!ers

Indications:

• Mana)e.ent

of GERD

• Mana)e.ent

of (1o(ena"

1"!ers -#ith

or #itho1t

anti,infe!ti+es for

H$ &"ori0

• Treat.ent of

&atho"o)i!

h&erse!reto

r

!on(itions*

in!"1(in)

o""in)er,

E""ison

sn(ro.e

Contraindications:

H&ersensiti+it

• CNS: (i55iness*

(ro#siness* fati)1e*

hea(a!he*

#ea%ness$

• C#: !hest &ain$

• GI: ab(o.ina" &ain*

a!i( re)1r)itation*

!onsti&ation*

(iarrhea* 4at1"en!e*

na1sea* +o.itin)$

• Derm: it!hin)* rash$

Misc: a""er)i!

rea!tions$

Pre+ent sto.a!

1"!ers



6/12

=at!h o1t for the fo""o#in) (r1),(r1) intera!tions

O.&era5o"e is .etabo"i5e( b the CJP@K en5.e sste. an( .a !o.&ete #ith other a)ents

.etabo"i5e( b this sste.

De!reases .etabo"is. an( .a in!rease e6e!ts of dia$epam* %ura$epam* tria$olam* cyclosporine

disul&ram* phenytoin* an( 'ar(arin

Ma interfere #ith absor&tion of (r1)s re?1irin) a!i(i! )astri! &H* in!"1(in) esters of ampicillin* iron

salts* digo)in* cyanocobalamine* an( *etocona$ole

Has been 1se( safe" #ith antacids• Assess &atient ro1tine" for e&i)astri! or ab(o.ina" &ain an( fran% or o!!1"t b"oo( in the stoo"* e.esis* or )astri!

as&irate$

• A(.inister (oses before .ea"s* &referab" in the .ornin)$ Ca&s1"es sho1"( be s#a""o#e( #ho"e< (o not !r1sh*

o&en* or !he#$

• Ma be a(.inistere( !on!1rrent" #ith anta!i(s$

• Instr1!t &atient to ta%e .e(i!ation as (ire!te( for the f1"" !o1rse of thera&* e+en if fee"in) better$ If a (ose is

.isse(* it sho1"( be ta%en as soon as re.e.bere( b1t not if a".ost ti.e for next (ose$ Do not (o1b"e (oses$

• Ma !a1se o!!asiona" (ro#siness or (i55iness$ Ca1tion &atient to a+oi( (ri+in) or other a!ti+ities re?1irin)a"ertness 1nti" res&onse to .e(i!ation is %no#n$

• A(+ise &atient to a+oi( a"!oho"* &ro(1!ts !ontainin) as&irin or NSAIDs* an( foo(s that .a !a1se an in!rease in G

irritation$

• A(+ise &atient to re&ort onset of b"a!%* tarr stoo"s< (iarrhea< ab(o.ina" &ain< or &ersistent hea(a!he to hea"th !a

&rofessiona" &ro.&t"

DRUG

ORDER


OF DRUG

INDICATIONS AND

CONTRAINDICATION

ADVERSE EFFECT OF

THE DRUG

DESIRED ACTIO

ON THE CLIEN


7/12

I&ratro&i1. sa"b1ta.o"

Phar.a!o"o)i! !"ass8Anti!ho"in

er)i!

The i&ratro&i1. in)re(ientis an anti!ho"iner)i! (r1)#hi!h re"axes s.ooth.1s!"e in the "1n)$

The sa"b1ta.o" in)re(ientis a beta, a)onist #hi!hsti.1"ates beta, sites in

the "1n)s to re"ax thebron!hi$

TE8 Re"ie+esbron!hos&as.s$

In(i!ations8

7ron!ho(i"ator for

.aintenan!e thera&

of bron!hos&as.$

Contrain(i!ations8

Contrain(i!ate( #ith

h&ersensiti+it toatro&ine or its

(eri+ati+es$

CNS8 (i55iness* b"1rre(+isionGI8 na1sea* (r .o1thRes&i8 (s&nea*bron!hos&as.s*horsenessCV8 &a"&itations* !hest&ain

To re"ie+ebron!hos&as.san( o&enair#as$



8/12

Monitor the &atient;s +ita" si)ns* notin) h&otension an( an irre)1"ar or abnor.a" &1"se$ Maintain a ?1iet* !o.fortab"e en+iron.ent to .ini.i5e anxiet an( &erha&s (e!rease &a"&itations$

Tea!h the &atient &1rse(,"i& breathin)* (ia&hra).ati! breathin)* an( !hest s&"intin)$

DRUG

ORDER


OF DRUG

INDICATIONS AND

CONTRAINDICATION

ADVERSE EFFECT OF

THE DRUG

DESIRED ACTIO

ON THE CLIEN


9/12

As&irin De!reases &"ate"et

a))re)ation$ Exhibits

anti&reti!* anti,

in4a..ator an(

ana")esi! e6e!ts$ The

anti&reti! e6e!t is (1e to

an a!tion on the

h&otha"a.1s* res1"tin) inheat "oss b +aso(i"ation of

&eri&hera" b"oo( +esse"s$

Anti,in4a..ator e6e!ts

are .e(iate( b a

(e!rease in &rosta)"an(in

snthesis$ It a"so

Indications:

• For &ain on

inte)1.entar

str1!t1res*

.a")ia*

ne1ra")ia*

hea(a!he*

(s.enorrhea*)o1t$

• Arthritis* SLE*

a!1te rhe1.ati!

fe+er

Contraindications:

• H&ersensiti+it

to sa"i!"ates*

se+ere ane.ia*

histor of b"oo(

!oa)1"ation

(efe!ts* +ita.in >

(e!ien!* #ee%

before an( after

s1r)er*

&re)nan! in the

"ast tri.ester

GI: (s&e&sia*

heartb1rn* anorexia*

na1sea* e&i)astri!

(is!o.fort*

&otentiation of &e&ti!

1"!er

Allergic:

7ron!hos&as.*asth.a,"i%e s.&to.s*

ana&h"axis* s%in

rashes* 1rti!aria

Hematologic:

&ro"on)ation of

b"ee(in) ti.e*

thro.bo!to&enia*

"e1!o&enia*

+ther: Thirst* fe+er*(i.ness of +ision

Pre+ent b"oo(

!oa)1"ation (1e

to h&ertension

-narro# b"oo(

+esse"s .a

!a1se b"oo( to

a))re)ate0



10/12

• Assess for &ain8 t&e* "o!ation an( &attern

• Note for asth.a

• Monitor rena"* LFTs an( C7C

• Deter.ine histor of &e&ti! 1"!ers or b"ee(in) ten(en!ies$

Precautions:

• Do not 1se in !hi"(ren #ith !hi!%en &ox or 41 s.&to.s

• La!tation

• Mi"( (iabetes* erosi+e )astritis* b"ee(in) ten(en!ies* "i+er or %i(ne (isease$


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12/12

Ceftriaxone Omeprazole Ipatropium Salbutamol Aspirin

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Transcript of Ceftriaxone Omeprazole Ipatropium Salbutamol Aspirin