Support for Pharma and Life Sciences Innovation
John O’Dea, Enterprise IrelandBio Pharma SummitOctober 2012
3
3
21 Enterprise Ireland’s Role
Support for Start-ups
Support for Industry
Agenda
What I Will CoverWhat I Will Cover
Supporting Innovation in Pharma and Lifesciences
• Innovation-Led High Potential Start-ups
• Client company investment in R&D
• Commercial return from state research
• Collaboration between industry and academia
• Drawdown by industry and academia from FP7 etc
• Seed and Venture Funds
Commercialisation Fund
Commercialisation Fund - Stages/ Go-No GoCommercialisation Fund - Stages/ Go-No Go
C PlusC Plus
Support for commercialisation of research from third-level institutions
Typically 2- 5 YEARS
BenchBench MarketMarket
CF feasibilityCF feasibility
Third Level Spin Outs
12
28
56
67
95 93
118
58
137
3531 31
0
20
40
60
80
100
120
2005 2006 2007 2008 2009 2010 2011
Nu
mb
er
LOAs
Spin outs
Date for your diary; Wednesday 28th November
Aviva Stadium
Technology Centres(~€2 million p.a. over 5 years)
EU FP7, ESA
Industry Led Research projects(~€2-3 million over 2-3 years)
Innovation Partnerships(up to €300k over 18 months)
R&D Fund: Small Projects [<€150k]Large Projects [<€650k]
Innovation Vouchers ( €5K)
Budget
NumberPartners
CollaborationComplexity
Innovation Support for industry
Technology Centres• Irish companies, multinationals, research institutions
• Undertake market-focussed strategic R&D
• Industry led
• Enterprise Ireland and IDA Ireland
Usually based in a University with support from partner colleges to deliver
on the research needs of the companies
Biorefining & Bioenergy IT InnovationApplied NanotechnologyComposite MaterialsMicroelectronics
Food for HealthManufacturing ResearchEnergy EfficiencyInternational Energy CentreLearning Innovation
Technology Centres
Connected HealthFinancial ServicesCloud Computing
Data AnalyticsPharmaceutical Manufacturing
Pharmaceutical Manufacturing PMTC • Improve manufacturing competitiveness of Irish sites and
companies
• Undertake research in advanced manufacturing technology with application to Irish pharma industry.
• Source additional funding through company projects and EU programmes .
• Showcase advanced pharmaceutical manufacturing expertise
• Support academic-industry collaboration
Pharmaceutical Manufacturing PMTC Initial research focus
Process Analytical Technology (PAT) to improve cost competitiveness through
• Rapid Microbiological assays
• Continuous Processing – as opposed to batch
• Soft sensors for process monitoring and control
• API-Real Time Release
• Packaging/authenticate/trace and security.Brendan Lawlor, Interim Research Manager
Industry-led Research Networks (ILRP)
• Medium-term 'shared agenda' research by groups of companies
• Research contracted to a publicly-funded research institution with funding from Enterprise Ireland
Animal Health
Finished Medical Devices & Medical Aids
Diagnostics
Innovation Partnerships
• Typically individual collaborative projects between companies and researchers
• Up to €300k
• Up to 80% funding from Enterprise Ireland
R&D Fund
Small company 45%Medium Company 35%Large Company 25%
Simplified Application for Small R&D Fund <€150k
So you want to start a technology business; How can we help?
100 new HPSUs per year, 20% Life-science
Indigenous 37%
MNC 32%
3rd Level 10%
Serial Promoter 16%
Other 5%
Most HPSU Entrepreneurs were managers inIndigenous Companies or MultinationalsMost HPSU Entrepreneurs were managers inIndigenous Companies or Multinationals
Background of Promoters
Business PartnersBusiness Partners
Where’s Sally?
EI AssistanceThe support you can get from us depends on where you
are.
1. Get to Investor Readiness• Build Business Plan
2. Raising investment
3. Growing the Business
We’re a Development
Agency
Mentor
Feasibility Study
Trade Fairs
Market information
Innovation Voucher Value Proposition Workshop
Seed CapitalCertification
Business Angels
Technology Assessment
Introduction to VCs
Investor Ready WorkshopsPitch preparation
New Frontiers Programme
Get to Investor ReadinessA Range of Supports
Large Market Opportunity [especially if VC needed]Barriers to Entry [current, future?]
High Growth, ScalableHigh Gross Margins
Large Market Opportunity [especially if VC needed]Barriers to Entry [current, future?]
High Growth, ScalableHigh Gross Margins
What we look for at Seed Stage
HPSU Investment
EI funding depends on exports, jobs & cash need
EI Investment is in equity [CCRPs] Minimum of matching external fundingAverage initial investment €250k
Due Diligence - the Business Plan• Market Risks• Execution Risks• Financial Risks
Due Diligence - the Business Plan• Market Risks• Execution Risks• Financial Risks
Funding
VC Funds€520 million
Seed Funds€124 million
Pre-Seed
Applied Process Consulting
Applied Process Consulting
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