3. 3 PACIFIC STATE MEDICAL UNIVERSITY ACTUAL PROBLEMS OF
EXPERIMENTAL, PREVENTIVE AND CLINICAL MEDICINE PROCEEDINGS OF THE
XIV INTERNATIONAL PACIFIC SCIENTIFIC CONFERENCE OF STUDENTS AND
YOUNG SCIENTISTS (APRIL, 18-19, 2013) Medicina DV Vladivostok 2013
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4. 4 I. - - .., .. , .. : ..., .. CLINICAL AND EPIDEMIOLOGICAL
ASPECTS OF HERPES ZOSTER VIRUS INFECTION Belomestnov I.V., Lee A.K.
At present, the most important problem of socially significant
infections are herpes infections, and especially in our country.
Given their prevalence in the population (according to different
sources, from 60 to 90%), a variety of clinical forms, a tendency
to chronic and recurrent course, the emergence of new resistant
mutant viruses, despite the wide range of drugs, and is not a high
level of quality of life patients, this actual problem is difficult
to overestimate. . , 3 , Varicella Zoster, , , , , . - - , 2 . 2012
. 74 15 45 , 23 . . 198 70,2%, 29,8%. 60 , 57%, 15 . 134 (67,7%) ,
64 (32,3%) . , , , , . : 141 (71,3%) , 39 (19,7%) - , . - ( 4% ), (
5% ). - . 14 (7%) Copyright & A K-C
5. 5 , . 4 (2%) . , - , 60 , . .., .. , . . ..., .. VALUE
NONINVASIVE TECHNIQUE FOR DIAGNOSING SKIN IN PRACTICE DOCTOR
DERMATOVENEROLOGY Dvoryaninova I.E., Taran M.G. The tumor of the
skin is actual problem for men. Recently the increase of the rate
of melanosarcomal nevi cases is registered, which is connected with
unfavorable ecologic influence and other factors. The patients with
nevi, papillomas, angiomas etc have been diagnosed and operated.
Dermatoskopya & ultrasonograpya is a contemporale metod for
diagnostic tumor of the skin. () . 100% , . . 10% 80%. , . . . . .
, , , , . . . . . . Copyright & A K-C
6. 6 , , . , , . .. , . . : ..., .. OPHTHALMOLOGIC
COMPLICATIONS WITH HERPES ZOSTER Borovskaya O.A. The actual problem
is that the herpes infection is the most common viral infection of
humans. Herpes Zoster in most cases is shown at the female
population. From 2009 to 2012 the tendency of growth of cases of
incidence of a herpetic infection is observed. , . 90% , 60% ( ). ,
250-300 . : - . : , 2. 110 . : 2009 122 , 2010 140; 2011 165; 2012
198. 2009 23 (19%) ; 2010 38 (27%); 2011 21 (13%); 2012 28 (14%). ,
, , , , . , , . , . : , (67%). 2009 2012 Herpes Zoster, Copyright
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7. 7 . Herpes Zoster , , (, , , , , ). , , . . . , . . . : ...,
. . PLACE OF PRURIGO SIMPLEX IN THE MORBIDITY STRUCTURE OF ATOPIC
DERMATITIS Vandysheva M. A. Prurigo is the heterogeneous disease
that is characterized by erithematous urticarial papules that are
intensely pruritic in symmetrical distribution, especially on the
extensor surfaces of the extremities, has the most persistent
current and resistance to conducted therapy. Prurigo simplex is one
of clinical forms of atopic dermatitis. . - . (IgE) - (). (1998)
L20 () ( ) L20.0 . ( ) , IgE . . - 1242 . IgE Micro Reader 4
(Hyperion, ). . . 1242 (46,5% 53,5% ). 189 (43,4% 56,6% ), 48,33 (
18 82 ). (23,2%) (24,3%) 51 60 . IgE, 189 , 2 . 1- (113 Copyright
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8. 8 ) IgE 100 /, 59 (65%) 54 (35%). 2- (34 ) IgE 100 /, 23
(70,6%) 53 (29,4%). . , 15,2%. IgE- 59,8%, IgE- 40,2%. . , HANTAAN
.. , . . : ..., .. CLINICAL FEATURES OF HEMORRHAGIC FEVER WITH
RENAL SYNDROME ASSOCIATED WITH SEROTYPE HANTAAN Verkhoturova V.I.
The analysis of case records of 65 patients with hemorrhagic fever
with renal syndrome, taking place in infection hospitals of
Primorsky region is done. It is shown that hemorrhagic fever with
renal syndrome associated with serotype Hantaan is characterized by
moderate intoxication and acute renal failure and a sufficient
frequency of liver insufficienty and hemorrhagic syndrome. - - . 3
: Hantaan, Amur Seoul. 65 , Hantaan, 2005-2012 . 6 - , . (, , , , -
). 16,133,6*109 /. , , , , . , . 17,7% , . 37,9% , - 13,9%. 57,5%
18,332,29 / 271,8332,25 / . 87,2% 1,440,72 /. , , . 69,5% :
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9. 9 -111,7319,86 /; - 94,2620,02 /. , . Hantaan- 57,2 %
122,8321,71*109 /. , , , . , Hantaan- . . . , . . : ..., . . THE
ANALYSIS OF SYPHILIS MORBILITY IN PRIMORYE Vlasova Y .S. The
analysis of syphilis morbility in Prymorye in 2009-2012. Situation
of syphilis sickness rate today and in last millennium are
characterized by difficult social economic and demographic chanches
in our country. The syphilis morbility stays in line of the most
important problem of native health service. . . : - . : 3 , 2009
2012. , , , . , 905 , : - 356 (35.9%), - 283 (31.2%), - 162
(17.9%), - 104 (11.4%). 2010 236 (26%), 2011 314 (34.6%), 2012 355
(39,4%). 45 (12,6%), 80 (22,4%), 84 (23,5%), 135 (37,9%), 12
(3,6%). 170(60%). : 18(11%), . 25(15,4), . 38(23,4%), Copyright
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10. 10 81(50%). 80% 13 18 . 95 (96%). , . - . 13 . , - . , ( ).
. . , . . . : ..., . . CLINICAL FEATURES SYPHILIS IN PATIENTS WITH
HEPATITIS C Gabrusenko A. L. Analyzed the clinical features of
syphilis in combination with hepatitis C. Co-infection with
syphilis and hepatitis C is characterized by the presence of
several syphilides simultaneously lengthening the permit syphilides
against the therapy. : . . : . : 12 . 2009 2012 . 53 %, 46. 7 %. :
25 %, : 75 %. 50 . : , 15 18 . . , , 85 % . , 12-15 10- 13 .
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11. 11 : , . , . -9 .., .. , . . : ..., .. THE ROLE OF SERUM
MMP-9 LEVEL IN DIAGNOSIS OF LIVER FIBROSIS AT THE STATE OF CHRONIC
VIRAL HEPATATIS C I.S. Gorelova S.V. Knysh. One of the important
factor in chronic inflammatory process is an activity of MMP-9. The
strong negative correlation between MMP-9 concentration and
fibrosis degree has been examined. Thereby the role of MMP-9 in
diagnostic of liver fibrosis at the state of chronic viral
hepatitis C has been confirmed. () . , () . , -9 (-9). : -9 . : -
41 (21 20 ) . . . -9 (R&D Diagnostics Inc., USA) 1 /. 14 .
Statistica 6,0 Windows. : (F0, n = 12), (F1-2, n = 14) (F3-4, n =
15) . -9 . , -9 F0 16950011200 /, F1-2 - 11070030500 / F3-4 -
5085011400 /, (p0,05) 48 . . 12 () , Copyright & A K-C
17. 17 48 () . .., .., .. , . . : ..., .. STUDY OF SOME OF THE
PARAMETERS OF THE CYTOKINE STATUS IN PATIENTS ENTEROVIRAL INFECTION
Mirgorodskaya N.V., Vlasenko A.U.,Voronuk A.S. In the scientific
aspects the infection became widespread teaching of CYTOKINE-
important regulators of the immune response of the cell type. The
aim of the work was to determine the cytokine status of the blood
serum of patients with different clinical variants of EVIE. The
obtained correlation of the studied indicators can be considered
diagnostically significant reaction of the body to EVIE. () . , . .
( TNF- ) ( 1 - TGF-1) (N=40). TNF- TGF-1 - (. ). 10 , . : () 25% -
75%. 52,5%, 47,5%. 23 . 2 5 (12-14 ). TGF-1 3,7 (44,72 12,04 /),
2,3 (27,75 12,04 /), (0,1). TNF- TGF-1 . Copyright & A K-C
18. 18 , TGF-1 , TGF-1 , , TNF- . - ..1 , ..2 , ..3 , ..1 , ..1
, ..1 1 , . . . . 2 , . . 3 , . . . : ..., .., ..., .., ..., ... ..
COMET ASSAY IN THE CLINIC OF INFECTIOUS DISEASES Mikhailov A.O.,
Slobodscova V.V., Kukla S.P., AnglichanovaK.Yi., Chernov P.N.,
Startsev M.G. It was found that two thirds of patients were with
lymphocyte DNA damage. Genetic damage index was 2.7, dominated
comet class C3. % DNA in the tail ranged from 5% to 57%. The above
changes were correlated with the severity of liver fibrosis and
observed mainly in patients with liver cirrhosis (F4). - ( -). (..,
2008), , (BertolasoL., 2008), (Zhanataev ., 2008), ( .., 2008). , ,
. , . 18 , 2 IV 2012 . 24 62 , 43 . 11 , 7. 2 27 , F0 F4 METAVIR.
10 . . -. 100 . (Cavas, 2008). Comet Score. Copyright & A
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19. 19 , 2/3 . 2,7, 3. 5% 57%. (F4). - . . , .. . : ... .. ,
... . . CLINICAL-EPIDEMIOLOGICAL FEATURES OF CONGENITAL SYPHILIS IN
THE PRIMORYE TERRITORY Mikhalik I.A. The author presents the
results of a survey of 42 children placed in childrens hospital of
the city of Vladivostok with suspected congenital syphilis for
2010-2012. The diagnosis of congenital syphilis was confirmed in
10(23,8%) children and 32(76,2%) children had preventive treatment
of congenital syphilis. - , . : , , , , , ( ), , , . 1 . 1 2010 31
2012 . 42 , 2010 2012 . : 2010 -23(55%) , 2011- 5 (12%), 2012- 14
(33%). : 10(23,8%) , 32 (76,2%) . 3 : 3 - 3 (7%) , 4 33 (78,5%), 1
2 - 6 (14,5%). -25 (59%), -17 (41%). 30 (71%) . , . Copyright &
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20. 20 . . . . , .. . : ..., . . PSORIASIS CLINICAL FEATURES
AMONG ADVANCED AGE PERSONS Myagkaya O. S. Big number of people with
psoriasis, atypical psoriasis forms and complications is fixed
during the last years. Clinical features of psoriasis among
advanced age persons such as plaque forms, widespread character,
generalize itch are revealed. The therapy approach has to be
complex and involve other section physicians. : , , , . : . : 87 60
, . : 2009 2012 . : 20-49 . : , 60 , 3.5 , 49 . 60 , . . 60 ( , , ,
) 78%, 20-49 12% . 60 - - , , . : 60 , , . Copyright & A
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21. 21 60 . .., .., .., . , . . . : . . ., .. FEATURES OF THE
IMMUNE STATUS OF PATIENRS WITH MONO AND CO HERPESVIRUS INFECTION
Ovakimyan K.M. Tyan K.V. Saybel A.V. Fatkiev R.Z. The immune status
of patients with mono and co herpesvirus infection is different.
Arise in the level of CD 20+ cells were revealed in patients with
mono herpesvirus infection. There is a decrease in the expression
of receptor positive (CD 25+) activation in co-herpesvirus. () - ,
, . - -, , -, , -. : . : 91 . . (Ig M,G,A) . - St.aureus, 100 , -
St. ureus, 1 . : , CD3+ CD4+ (CD25+) (CD95+) . CD25+ , . CD20+ ;
(CD25+) . Ig A , . Copyright & A K-C
22. 22 .. , .. . . : ..., .. HISTORY OF THE DEVELOPMENT OF THE
INFECTIOUS SERVICE IN PRIMORSKY REGION Pilipenko I.S., Popova E.V.
The First infectious department in Vladivostok became to function
in 1872 at military hospital, in 1898 infectious department at
Vladivostok town hospital was opened. In 1934 infectious hospital 1
was opened. At the following years infectious permanent
establishments, cabinets of the infectious diseases were opened. By
2013 in Primorsky Region there are 1121 infectious beds, 85
consulting rooms, 115 specialists on infectious diseases. 22 1872 ,
120 . .. . . 1893 . 18 1898 . . .. 1903 . 25 . 70 . , , , , , , , .
. 1934 . 1 . . . . , 7 200 : 81 , 55 , 25, 25 14 . 1940 . .. , 1970
. 2012 . . , . 1961. . 2013 1121 32 , 1 . 85 . 115 -, 42,6% , 14,8%
- , 7,8 % - . Copyright & A K-C
23. 23 - .. , .. : ..., .. CLINIC OF CHRONIC VIRAL
HEPATITIS-MIXED ETIOLOGY Putilova E.A. A comprehensive clinical and
laboratory study of 120 patients (64 women and 56 men) took place,
of them - 60 people with the mixed hepatitis B + C, B + D, B + D +
C. Anamnestic data analysis showed the absence of acute hepatitis
in the majority of patients. The most characteristic feature was
the undulating course of the disease, when during acute identify
new or previously amplified symptoms. In patients with chronic
viral hepatitis, despite the paucity of symptoms, quite pronounced
polymorphism symptoms were revealed. - 120 (64 56 ). 30 . HCV- , 30
. HBV- 60 . -: +, +D, B+D+C. (78,46,3%). , . - : (94,61,5%);
(93,81,8%) (55,49,1%). - , -. (rS=0,8) (rS=0,5) , (rS=0,5),
(rS=0,7). (2 =0,7; =1 .; p