URCA powerpoint pwpt
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![Page 1: URCA powerpoint pwpt](https://reader034.fdocument.pub/reader034/viewer/2022042513/5880e45f1a28ab0d358b5579/html5/thumbnails/1.jpg)
Diffusion Spectrum Imaging: New ways of reconstructing
long-range connections in the brain
Presented by Sophia Larriva with work by Alex Asturias, Viktoriya Babenko, Matt Cieslak, Celine Mol, and Scott Grafton, PhD.
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What is all this?• Brain has many overlapping connections
• Neurons• White matter
• Different connections are different!
Split Brain: Corpus Callosum
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Left Lateral Occipital to Left Inferior Temporal
• Diffusion MRI looks at water movement
• Constrained by axon bundles
• Maps out connections (speech, visual pathways, etc.)
• Clinical uses for strokes and certain types of injuries
Right Superior Parietal to Brain
Stem
Some Background
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Recent InnovationsDTI scan
2007 DSI scan 2015 DSI scan• Scan time=
under 20 minutes• Can determine
directions for crossing fiber tracts
• Multi-band imaging protocols
• Scan time= 6 minutes
• Cannot resolve crossing fibers
• More variability in results interpretations
• Scan time= 1 hour
• Determine directions for crossing fiber tracts
• Single-band imaging protocols
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A Comparison of Scans• Center for Magnetic Resonance Research at University of
Minnesota (CMRR)• Siemens Corporation
• Examined differences in signal quality
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ResultsCMRR Wins! (almost outright)
Neuronal fiber tracts (axons) where Siemens appeared better were statistically insignificant/not real
Right Paracentral Gyrus to Left Paracentral Gyrus
Right Entorhinal Cortex to Brain Stem
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What Now?Potential Clinical Uses
• Surgery• Monitoring Fetal Development• Stroke Patients
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References
-http://definingsolutions.ca/wp-content/uploads/2013/10/split-brain.gif-http://www.cguy.net/wireless_networking_guide/images/p2p%20connection.jpg-http://www.humanconnectome.org/img/art/pulse-sequences-fig3.png-http://upload.wikimedia.org/wikipedia/commons/3/36/MCA-Stroke-Brain-Human-2.JPG-http://www.h3dwallpapers.com/wp-content/uploads/2014/10/Cute_baby_pics.jpg-http://www.the-scientist.com/Nov2014/whitematter2.jpg
Thank You!