Temporal Enhancement of Motor Control in Parkinson’s Disease

patients

Marta Bieńkiewicz

PhD StudentQueen’s University Belfast

Temporal Enhancement ofMotor Performance Using SensoryGuides

Temporal control of the movement

Difficulties with timing the movement in Parkinson’s Disease

Using cues to stimulate perception action coupling

Clinical symptoms of idiopathic Parkinson’s Disease

• Four major motor dysfunctions: bradykinesia

rigidity tremor at rest

postural instability

bradykinesia

1 /500 in UKEvery year 10,000 are

diagnosed (www.parkinsons.org.uk)

Progressive neurodegeneration

Anatomically Parkinson’s Disease exhibits a progressive degeneration of the substantia nigra cells that are interconnected with dopaminergic neurons in the striatum part of the basal ganglia.

Anatomically Parkinson’s Disease exhibits a progressive degeneration of the substantia nigra cells that are interconnected with dopaminergic neurons in the striatum part of the basal ganglia.

Paradoxical kinesia

Asmus et al. (2008). Kick and rush: Paradoxical kinesia in Parkinson disease.Neurology.2008; 71: 695

Perception and action coupling

Action

Perceptual information available

none intermittent continuous

Temporal control

intrinsic intrinsic/extrinsic extrinsic

PARADOXICAL KINESIA

Pilot – Parkinson’s Disease

Self-paced Moving ball

Pilot – Parkinson’s Disease

Self-paced No vision – moving ball

HEIGHT OF THE RAMP

Research questions

• 1.) How PDs and healthy adults differ in temporal control of the movement under different spatial, temporal and informational constraints?

• 2.) Can paradoxical kinesia be explained by coupling the movement to the sensory information available?

Goals

Aritifical Sesory Guides in PD.

Goal-directed actions.

Effectiveness of cueing methods.

Focus

1.) Upper limb movements

2.) Turning

3.) Freezing

Special thanks to:Dr Cathy CraigDr David Craig

Will Young

TEMPUS GG

Thank you for your attention!

mbienkiewicz01@qub.ac.uk