PYTHIOSIS .
Transcript of PYTHIOSIS .
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PYTHIOSISPYTHIOSIS
http://www.pythiosis.com/images/rusty1.JPG
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What is it?!What is it?!
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pythium insidiosumpythium insidiosum
Class OomyceteClass Oomycete Aquatic pathogenAquatic pathogen Not true fungiNot true fungi
http://www.mycology.adelaide.edu.au/images/pithium.gif
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http://www.pf.chiba-u.ac.jp/gallery/img/fungi/p/Pythium_insidiosum_colonies.jpg
http://www.pythiosis.com/fieldtrial_files/image002.jpg
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http://www.pf.chiba-u.ac.jp/gallery/img/fungi/p/Pythium_insidiosum_microscopy.jpg
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Life CycleLife Cycle
In nature In nature
Infective process Infective process
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC266174/
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Who gets it?Who gets it?
RarelyRarely CutaneousCutaneous G.I.G.I.
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Increasing prevalenceIncreasing prevalence G.I.G.I. Rarely cutaneousRarely cutaneous
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Cutaneous Cutaneous
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http://farm1.static.flickr.com/109/272790598_61bb05b8a8.jpg
http://lh6.ggpht.com/_yElYiq7gRbk/RyfBMDU6W3I/AAAAAAAAAdM/PoYIiiBBa7k/IMG_0582.JPG
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http://msnbcmedia.msn.com/j/ap/4f71e2f6-c001-46ad-afee-e7cf6dab8b4e.hlarge.jpg
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What does it look like?What does it look like?
http://school.discoveryeducation.com/clipart/images/look---.gif
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http://pythium.pavlab.com/images/Cat%20leg.jpg
http://pythium.pavlab.com/images/cat%20abdomen.jpg
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http://pythium.pavlab.com/images/Dog%20leg%20pythiosis.jpg
http://pythium.pavlab.com/images/dog%20pythiosis.jpg
http://pythium.pavlab.com/images/respiratory.jpg
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http://www.ecmagazine.net/spring2008/photos/pythiosis1.jpg
http://pythium.pavlab.com/images/horse%20neck%20leg.jpg
http://www.userltriangle.org/Cisco%20June%2019,%202007%20-%20pic%201.jpg
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http://www.scielo.br/img/fbpe/pvb/v21n4/7481f3.jpg
http://img.tfd.com/vet/thumbs/gr297.jpg
http://upload.wikimedia.org/wikipedia/commons/thumb/b/b9/Pythiosis_2.jpg/120px-Pythiosis_2.jpg
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http://bld.msu.edu/images/bonepith.jpg
http://www.merckvetmanual.com/mvm/htm/bc/genfg30.htm
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http://www.scielo.br/img/revistas/pvb/v29n11/a13fig01.gif
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What about intestinal What about intestinal pythiosis?pythiosis?
Anywhere Anywhere Thickening (U/S & Barium)Thickening (U/S & Barium) Granulomatous + hyphaeGranulomatous + hyphae Clinical signs vagueClinical signs vague
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How will I diagnose this?How will I diagnose this?
Non-healing granulomatous cutaneous Non-healing granulomatous cutaneous lesionslesions
Fungal cultureFungal culture PCRPCR Serum ELISASerum ELISA
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treatment optionstreatment options
Surgical resection Surgical resection +/- Itraconazole+/- Itraconazole Immunotherapy in horses (and dogs?)Immunotherapy in horses (and dogs?) Early diagnosis KEYEarly diagnosis KEY
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What is it?
Necrotic and purulent foci within the sole of the hoof
Clinical signs: Acute Severe lameness Pointing toe Blocks sound Positive to hoof testers Increased digital pulse +/- fever Draining tracts
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What causes it?What causes it?
Puncture wounds (big hole vs little hole)Puncture wounds (big hole vs little hole)
http://www.foxtailforge.com/images/abscess_1.jpg
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Also…Also…
Sub-solar abscess Sub-solar abscess
http://www.farriervet.com/images/lam6.jpg
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More?More?
Result of bruising Result of bruising
http://i.ehow.com/images/a04/bn/cj/thoroughbred-racehorses-200X200.jpg
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Poor trimming techniquePoor trimming technique
http://www.eponashoe.com/Documents/On%20the%20Comments_files/thumb012.jpg
http://easycareinc.typepad.com/.a/6a00d83451606969e2010536c67fce970b-320wi
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Radiographically?Radiographically?
May see draining tracts May see draining tracts Solar defectsSolar defects Septic osteitisSeptic osteitis
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Treatment options?Treatment options?
Benign neglectBenign neglect Soaking/PoulticingSoaking/Poulticing LancingLancing Surgical resectionSurgical resection Antibiotics Antibiotics
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www.vin.com
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www.equinepodiatry.com