Predictions Suggesting a Participation of β-Sheet Configuration in the M2 Domain of the P2X7...

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Predictions Suggesting a Participation of β-Sheet Configuration in the M2 Domain of the P2X7 Receptor: A Novel Conformation? Pedro Celso Nogueira Teixeira, Cristina Alves Magalhães de Souza, Mônica Santos de Freitas, Débora Foguel, Ernesto Raul Caffarena, Luiz Anastacio Alves Biophysical Journal Volume 96, Issue 3, Pages 951-963 (February 2009) DOI: 10.1016/j.bpj.2008.10.043 Copyright © 2009 Biophysical Society Terms and Conditions

Transcript of Predictions Suggesting a Participation of β-Sheet Configuration in the M2 Domain of the P2X7...

Page 1: Predictions Suggesting a Participation of β-Sheet Configuration in the M2 Domain of the P2X7 Receptor: A Novel Conformation? Pedro Celso Nogueira Teixeira,

Predictions Suggesting a Participation of β-Sheet Configuration in the M2 Domain of the P2X7 Receptor: A Novel Conformation? 

Pedro Celso Nogueira Teixeira, Cristina Alves Magalhães de Souza, Mônica Santos de Freitas, Débora Foguel, Ernesto Raul Caffarena, Luiz Anastacio Alves 

Biophysical Journal Volume 96, Issue 3, Pages 951-963 (February 2009)

DOI: 10.1016/j.bpj.2008.10.043

Copyright © 2009 Biophysical Society Terms and Conditions

Page 2: Predictions Suggesting a Participation of β-Sheet Configuration in the M2 Domain of the P2X7 Receptor: A Novel Conformation? Pedro Celso Nogueira Teixeira,

Figure 1

Biophysical Journal 2009 96, 951-963DOI: (10.1016/j.bpj.2008.10.043) Copyright © 2009 Biophysical Society Terms and Conditions

Page 3: Predictions Suggesting a Participation of β-Sheet Configuration in the M2 Domain of the P2X7 Receptor: A Novel Conformation? Pedro Celso Nogueira Teixeira,

Figure 2

Biophysical Journal 2009 96, 951-963DOI: (10.1016/j.bpj.2008.10.043) Copyright © 2009 Biophysical Society Terms and Conditions

Page 4: Predictions Suggesting a Participation of β-Sheet Configuration in the M2 Domain of the P2X7 Receptor: A Novel Conformation? Pedro Celso Nogueira Teixeira,

Figure 3

Biophysical Journal 2009 96, 951-963DOI: (10.1016/j.bpj.2008.10.043) Copyright © 2009 Biophysical Society Terms and Conditions

Page 5: Predictions Suggesting a Participation of β-Sheet Configuration in the M2 Domain of the P2X7 Receptor: A Novel Conformation? Pedro Celso Nogueira Teixeira,

Figure 4

Biophysical Journal 2009 96, 951-963DOI: (10.1016/j.bpj.2008.10.043) Copyright © 2009 Biophysical Society Terms and Conditions

Page 6: Predictions Suggesting a Participation of β-Sheet Configuration in the M2 Domain of the P2X7 Receptor: A Novel Conformation? Pedro Celso Nogueira Teixeira,

Figure 5

Biophysical Journal 2009 96, 951-963DOI: (10.1016/j.bpj.2008.10.043) Copyright © 2009 Biophysical Society Terms and Conditions

Page 7: Predictions Suggesting a Participation of β-Sheet Configuration in the M2 Domain of the P2X7 Receptor: A Novel Conformation? Pedro Celso Nogueira Teixeira,

Figure 6

Biophysical Journal 2009 96, 951-963DOI: (10.1016/j.bpj.2008.10.043) Copyright © 2009 Biophysical Society Terms and Conditions

Page 8: Predictions Suggesting a Participation of β-Sheet Configuration in the M2 Domain of the P2X7 Receptor: A Novel Conformation? Pedro Celso Nogueira Teixeira,

Figure 7

Biophysical Journal 2009 96, 951-963DOI: (10.1016/j.bpj.2008.10.043) Copyright © 2009 Biophysical Society Terms and Conditions