PPT_Yi Ting Loo (Symposium)
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Transcript of PPT_Yi Ting Loo (Symposium)
![Page 1: PPT_Yi Ting Loo (Symposium)](https://reader036.fdocument.pub/reader036/viewer/2022081520/58a871031a28ab90568b55d7/html5/thumbnails/1.jpg)
What Is Good About Resistant Starch?
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Presenter: Yi Ting Loo
Resistant Starch As An Alternative Strategy to Improve Vitamin D Status in Type 2 Diabetes
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Type 2 Diabetes (T2D) & Vitamin D (VD) About Resistant Starch About Research Study
Objective Methods Results Conclusion
Agenda
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Two forms of VD- 25D & 1,25D
Kidney is important for VD Kidney disease causes low VD status Kidney disease is common in T2D
25 D 1,25DActivate
Relationship Between T2D & VD
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A type of fermentable fiber Not digested Fermented in colon Low glycemic food
What Is Resistant Starch (RS)?
Potential for Diabetes Management
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What Can RS Help in Diabetes?
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Objective of The Study
Prevent loss of VD
Maintain serum 25 D
concentrations
Zucker Diabetic Fatty Rats (ZDF)
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Control Diet (Cornstarch)
Treatment Diet(RS)
Lean Control
(LC group)n= 8
ZDF(DC group)
n= 8
ZDF (DRS group)
n= 8
Diet
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After 6 weeks of treatment, we collected:UrineBloodKidney
Sample Collections
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What we found…
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Body Weight
LC
DRS
DC
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594mg/dL
351mg/dL
41% lower
Fasting Blood Glucose
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Indications of Kidney DamagePolyuria ↑ excretion of protein & albumin↓ excretion of urinary creatinine
RS PREVENT these!
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Urinary Volume, Protein, Albumin, Creatinine
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Urinary Volume, Protein, Albumin, Creatinine
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21% lower
Kidney Damage
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41% higher
Serum 25D
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89% lower
97% lower
Urinary Loss of 25D & 1,25D
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Conclusion
RS protect kidney health
maintains VD status in T2D
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Gar Yee K, Whitley E, Rowling M, et al. Dietary Resistant Starch Prevents Urinary Excretion of Vitamin D Metabolites and Maintains Circulating 25-Hydroxycholecalciferol Concentrations in Zucker Diabetic Fatty Rats. Journal Of Nutrition [serial online]. November 2014;144(11):1667-1673. Available from: Academic Search Premier, Ipswich, MA. Accessed February 10, 2015.
References
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Questions?
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Thank You!