Portable Magnetic Resonance Devices. NMR A spinning magnet in a magnetic field will precess Larmor...
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Transcript of Portable Magnetic Resonance Devices. NMR A spinning magnet in a magnetic field will precess Larmor...
Portable Magnetic Resonance
Devices
NMR
A spinning magnet in a magnetic field will precess
Larmor frequency ω = γ BResonance – absorb energy
Radio frequency for nucleiEnergy decay, relaxation times
T1 spin-lattice T2 spin-spin
Task 1
Nuclear Magnetic Resonance
What are the basic principles?
MRI
Need spatial information to form imageMagnetic gradientsRF pulse sequencesPhase encoding
Conventional MRI
Uniform Magnetic field 1 part per million
Field gradients superimposed to perturb field in defined way spatial information
RF Pulse sequences image contrast combinations of relaxation times
Task 2
Magnetic Resonance Imaging
How did NMR develop into MRI?
What are the essential requirements?
Hospital MRI
Large - fills a roomExpensive to buy
~£1M
Expensive to run ~£100k p.a.
Hospital MRI
Superb imagesHigh resolutionMultipurpose
Idea – Portable!
Permanent magnetNatural inhomogeneities
(But not too much!)
Local relaxation times (0D)‘images’ (1D, 2D, 3D)
Portable MR
Small - suitcase?Cheap - ~£10’s thousandsTailored for specific
applications?
Task 3
Magnetic Resonance Imaging
Are there any uses for small (portable) MR devices?
Work out the design specifications You might require for these applications.
Task 4
Magnetic Resonance Imaging
How can we make it small?
Can you devise ways of meeting the design criteria of Task 3?
Task 5
Magnetic Resonance Imaging
Can you identify devices in whichothers have attempted to meetthe challenge?
Aachen
http://www.nmr-mouse.de/
the MObile Universal Surface Explorer or the NMR-MOUSE®
Bernhard Blümich
http://www.aixnmr.com/
Berkeley
http://waugh.cchem.berkeley.edu/research/index.php?rescat=8
http://chemistry.berkeley.edu/Publications/news/spring2005/nmr.htm
Portable High-Resolution NMR Sensor