Aagami, Inc.

Connecting Midwest High Tech

Startups With India

…LifeSciences Catalyst

MRUN Conf - Oct 12, 2012

Dinesh Jain, Founder CEO

Topics covered

India – an Introduction

IN Lifesciences Industry snapshot

Major centers of Lifesciences in India

Major Deals and Investments showing

India as a Market Place

India as a Resource Place

What Indian LS firms are looking for

How Aagami Supports Companies

Lifesciences Catalyst 2

India – a Brief Introduction (V-IMP)

Nation of 1.22 Billion people (~EU+Africa)

28 States and 7 Union Territories

22 Official languages – English is widespread

Ancient Civilization – Young Nation

Most Heterogeneous and complex

Very Traditional Yet quite Modern

Last 20 years GDP CAGR at ~7%

3rd Largest economy of the world in PPP (IMF)

Sizeable # of Rich, yet average person very poor

Sci, Tech and Business excel, poor Infrastructure

Lifesciences Catalyst 3

Indian LS Industry Snapshot

3rd Largest Pharma market (by volume)

LS Market ~ $25B, Healthcare ~ $65B

Over 20,000 Pharma/BT companies

Top 20 Companies have presence in Regulated

markets (US, Canada, Western EU and Japan)

Top 100 companies are present in 50+ countries

Globally successful in Generics

“Every 3rd pill in the world is Made in India”

Medicine Source of the developing world

WHO sources over 70% from India

Largest # of US FDA approved mfg facilities

Lifesciences Catalyst 4

Indian LS Industry Snapshot…cntd

Biotech Industry with exploding growth

Largest pool of Chemists and Biologists

Abundant specialty health institutions 14000+ Hospitals, 700,000+ Beds

Large Pool of Medical professionals ~200 Medical Colleges graduating 30,000+ doctors per year

600,000+ Doctors

Largest pool of Biosciences Graduates Per

annum - 3 Million B.S., 700,000 M.S., 15000 Ph Ds

Indian Regulation – a Super Set of US-FDA

All Technical & Business work in English

Lifesciences Catalyst 5

Major Centers of LS Business

City – Major Companies Mumbai – Sun, Lupin,Wockhardt, Glenmark,

USV, Piramal, Ipca, Most MNCs

Ahmedabad – Zydus, Intas, Cadila, Torrent

Hyderabad – Dr. Reddy’s, Aurobindo, Suven,

Divi’s, Hetero, Shantha, Bharat

Bengaluru – Biocon, Micro, Strides, GSK,

New Delhi – Ranbaxy, Panacea, Jubilant

Chennai – Orchid, Shasun, Tablets India,

Pune – Bilcare, Serum India, Advinus,

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Major Centers of LS Research

City – Research Institutes New Delhi – ICPO, IGIB, TERI, ICGEB, IofPath, NIMS,

NIMR, NIPGR,

Hyderabad – ICRISAT, CCMB, IICT, CDFD, ILS, LVP

Eye, NCLAS, NIN, ISB,

Pune – NCL, Agarkar, Micobial Complex, NARI, NCCS,

NIV,

Mumbai – TIFR, BARC, Genetic RC, ICT,

Ahmedabad – NIPER, NIOH, NSD, IIM,

Bengaluru – IISc, NCBS, IBioInfoABio,

Kolkata – Guha CGEB, IICB, NICED,

Chennai – Biosys BT, CLRI, NIE, TBRC,

Nagpur – ICAR, CI Cotton R, NEERI, NIIPM, NRCC

Lucknow – CDRI, CI Med & A Plants, IIToxR, NBRI, Lifesciences Catalyst 7

Major Intl Deals and Investments

Wockhardt – Morton Grove, IL

Sun – Caraco, MI, & Taro Israel

Dr. Reddy’s – BetaPharm, DowPharma, BASF

Lupin – Kyowa, Japan

Piramal – Design Resource Group, MA

DaiIchi Sankyo – Ranbaxy

Abbott – Piramal Pharma (Shifting generic mfg)

Sanofi – Shantha Biotech

GSK – Large R&D center

Fresinius Kabi – Large Development Center

Merck, Estellas, Takeda, Biogen, Amgen, started

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Latest Relevant News ….

Oct 11 – Pharma industry creates 2nd most # of billionaires

Oct 7 - India US announce Jt Research in BT

Oct 5 – Takeda in $90 M Discovery deal with Advinus

Sep 30 – DBT and ABLE roadmap for a $125B by 2025

Biotech industry from $4B in 2011

Sep 14 – Piramal to launch own innovative drug in EU

Sep 12 – Panacea forms JV with US’ Osmotica

Jul 4 – Serum acquires Dutch firm Bithoven for $100M

Jul 2 – AstraZeneca & Cellworks to design TB therapies

Jun 20 – Novozymes & Praj to jtly develop Biofuels

Jun 4 – Abbott sets Nutri research center with Biocon

Apr 21 – Merck to set up $150M vaccine lab in Delhi Apr 16 – Piramal acquires Imaging R&D portfolio of Bayer

Lifesciences Catalyst 9

Indian Firms are looking for

Partnerships, Investment, Licensing or

Acquisitions of

Innovative compounds and technologies

Co-Development Opportunities

Novel Drug Delivery Systems

Manufacturing in IN and the US

Companies in Regulated markets

Lifesciences Catalyst 10

Aagami Consulting Services offer

In-Licensing or Out-Licensing

Co-Development and Partnerships

Mergers & Acquisitions

Investments to and from India

Finding the Right

JV partners and/or Distributors

CRO and CRAMS providers

Contract Sales/Marketing companies

Contract Manufacturing companies

Lifesciences Catalyst 11

Aagami brings

Extensive Operational Experience Globally

Deep Understanding of business and socio-

cultural differences in ways of working

Extensive network with top 100 Indian LS

companies at CXO levels

Deal experience with Western, Japanese and

Indian industry

Dedicated team with focus on Client success

Lifesciences Catalyst 12

Business Cultural Differences sample

Phrases and points in the US vs IN

Confidential Lifesciences Catalyst 13

•As Soon as Possible : ASAP vs ASAP

• Tomorrow : Next day vs In near future

• Will be done : surely be done vs will try best

• Business focus : Specialist vs Generalist

• Work driven by : Process vs Ad Hoc

• Everyday working : MBO vs MBC

• Business Xaction : Contractual vs Trust base

• Importance : Transaction vs Relationship

Sample List of Aagami Clients

USA Dow - MI

Aegis – CA

Advangene – IL

MacuCLEAR – TX

DesignMedix – OR

Unitech Pharma – MI

Loyola U Chicago – IL

MW Univ. – IL, AZ

PLx - TX

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International

Solvay - Belgium

Delmar - Canada

SOM Biotech - Spain

Phosphagenics - Australia

NanoSensing - Brazil

Affitech - Denmark

Ilsan Ilvac - Turkey

Pieris - Germany

Toppan – Japan

Our Approach

Prepare ‘Elevator Pitch’ on client technology and/or company

customized to Specific business culture for e.g. India, Japan

Identify Relevant Companies from our Database and resources

Broadcast EP to Relevant Companies by email

Follow-up with phone calls and emails with all

Coordinate CDAs with interested Companies, and supply further

info thru emails and conference calls

Organize a road show to India along with client representative/s

Take appointments with right executives in interested companies

Coordinate the logistics of the road show (v imp)

Support in structuring and negotiations for finalizing the deal(s)

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Aagami, Inc.

2020 Calamos Ct, Suite 209

Naperville, IL 60564

Phone: (630) 799-1572

dinesh@aagami.net

www.aagami.net

Realizing Possibilities with

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