Mechanism
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Mechanism
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Mechanism. NH2. O. N. H. N. C. P. O. CH2. N. N. OH. CH2. R. H. O. Glutamine. OH. O. P. Phosphoribulosyl-formimino-5-AICAR-P. Glutamine amidotransferase. P. O. CH2. N. OH. Glutamate. C. NH2. H. N. H. OH. N. O. Imidazole glycerol phosphate. N. H2N. R. AICAR. - PowerPoint PPT Presentation
Transcript of Mechanism
Mechanism
CH2OP
OH
CH2
N
O
C
N
CH2OP
OH
N
N H
OH
H
H
OH
Glutamine
Glutamate C
Imidazole glycerol phosphate
Glutamine amidotransferase
H
O
NH2
N
N
R
O
P
H2N
NH2
N
N
R
O
P
O
Phosphoribulosyl-formimino-5-AICAR-P
AICAR
CH2OP
OH
CH2
N
O
C
N
H
OH
H
O
NH2
N
N
R
O
P
Phosphoribulosyl-formimino-5-AICAR
CH2OP
OH
CH2
N
O
C
H
OH
H2N
O
NH2
N
N
R
O
P
H
O
H
+
AICAR
Purine Synthesis
Histidine
CH2OP
OH
CH2
N
O
C
O
H
H3N
COO
H
CCH2
H
H
OH
+
-
Glutamine
C
O
H2N
CH2H
CH2O
OH
CH2
N
O
CP
OH
H
H
OH
H N
H
H
CH2O
OH
CH2
N
O
CP
H
H
OH
H N
HOH
CH2O
OHCH
N
OH
C
P
H
OH
H
N
H
Imidazole glycerol phosphate
CH2O
OH CN
C
P
H
OH
H
N
