7/22/2019 Lidocaine 5% Leaflet

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LIDOCAINE 5%

KOMPOSISI :

Lidocaine 5%Injeksi, tiap ml mengandung : Lidocain HCl Monohidrat setara dengan Lidocain HCl 50

mg.

DESKRIPSI :

Lidocaine 5% dengan zat aktif Lidocain HCl Monohidrat setara dengan Lidocain HCl! tersedia dalam

"entuk injeksi 50 mg#ml. Lidocaine 5%adalah larutan hiper"arik Lidocain HCl dalam $e%trose 5&

untuk anestesi spinal.

'umus molekul : C()H**+*.HCl.H*

-erat molekul : *.0

/truktur kimia :

+ama kimia : *diethlamino!*1, 234aceto%lidide monohdrochloride monohdrate

FARMAKOLOGI :

/e"agai lokal anestesi ang sangat luas. enggunaanna se"agai larutan injeksi dan pemakaian lokal pada

mucosa mem"ran. Lidocain HCl cepat "ekerja dan cepat mene"ar ke seluruh jaringan, efekna le"ih

intensif dan le"ih lama tahan daripada protein.

INDIKASI :

Lokal anestesi.

DOSIS DAN CARA PEMBERIAN :

( 6 * ampul tergantung keperluan pemakaian oleh dokter. Maksimum * ampul.

Cara pemakaian : Intra muskular # su"kutan.

KONTRAINDIKASI :

Hipotensi.

PERINGATAN DAN PERHATIAN : ada penderita dengan kerusakan hati dianjurkan memakai dosis Lidocain ang sekecil4kecilna.

7fek o"at diikuti le"ih cermat pada gangguan ginjal se"a" Lidocain dimeta"olisme le8at "agian4

"agian ini.

INTERAKSI OBAT :

9om"inasi pem"erian Lidocain dan "ahan4"ahan antiaritmia lain dapat mene"a"kan suatu efek

kom"inasi cardiac depresan.

olongan -ar"iturat dapat mempertinggi disposisi dari Lidocain.

$iphenlhdantoin dan Lidocain mempunai efek cardiac depresan ang aditif.

Isoproterenol juga mempertinggi disposisi dari Lidocain se"a" dapat mempertinggi hepatic "lood

flo8.

ropanolol memperlam"at disposisi Lidocain dengan mengurangi hepatic "lood flo8.

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-ila larutan Lidocain * ;g#l dicampur dengan Methohe%ithon +a * g#l akan segera terjadi endapan.

* ml +o. 'eg : 9L((0*?)5?)?@(

/IM@+ @$@ /AHA 9@M@' *54?0!BC, 7'LI+$A+ $@'I C@H@D@

HARUS DENGAN RESEP DOKTER

$iproduksi oleh :

.-7'+E@'M

/idoarjo4Indonesia

anggal re=isi : ** @gustus *0((

OGB: "at enerik -erno

UNTUK KETERANGAN LEBIH LANJUT :

e4mail : info>"ernofarm.com. -F. )0?G

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LIDOCAINE 5%

COMPOSITIONS:

Lidocaine 5% Injection, each ml contains : Lidocaine HCl Mohohdrate eui=alent 8ith Lidocaine HCl

50 mg.

DESCRIPTIONS :

Lidocaine 5%contains Lidocaine HCl Monohdrate eui=alent 8ith Lidocaine HCl! is a=aila"le in 50

mg#ml injection. Lidocaine 5% injection is a hper"aric Lidocaine HCl solution in de%trose 5& for

spinal injection.

Molecular formula :C()H**+*.HCl.H*

Molecular 8eight : *.0

/tructural formula :

Chemical name : *diethlamino!*1, 234aceto%lidide monohdrochloride monohdrate

PHARMACOLOG :

@s e%tensi=e local anesthetic. It ma use as injection solution and local mucosal mem"ranes. Lidocaine

HCl has rapid effect and uickl spread throughout the "od tissues, this effect is more intensi=e and

longer than protein plasma.

INDICATIONS:

Local anesthetic.

DOSAGE AND ADMINISTRATIONS :

( 6 * ampoules depending on the purposes of usage " phsician. he ma%imum dose is * ampoules.

@dministration : Intramuscular # su"cutan.

CONTRAINDICATIONS:

Hpotension.

!ARNING AND PRECAUTIONS : atients 8ith li=er damage ma recommended using the lo8est dose of Lidocaine.

$rug effects is more closel monitored in renal disorder, since Lidocaine is meta"olized through the

parts of kidne.

DRUG INTERACTIONS :

Concurrent administration of Lidocaine and other antiarrhthmic drugs ma cause com"ination

effect of cardiac depressant.

-ar"iturate drugs ma enhance disposition of Lidocaine.

$iphenlhdantoin and Lidocaine ha=e additi=e cardiac depressant effects.

/ince Isoproterenol ma enhance the hepatic "lood flo8, it ma also enhance disposition of

Lidocaine

ropanolol ma dela disposition of Lidocaine " reducing the hepatic "lood flo8.

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recipitation is imminent if * ;g#l Lidocaine solution is mi%ed 8ith * g#l Methohe%inthon sodium.

Crstalline precipitation is also imminent if * ;g#l Lidocaine solution is mi%ed 8ith ) g#l /ulfadiazine

sodium in de%trose injection solution.

AD"ERSE REACTIONS :

atients feel dizz and dro8siness in the use of high doses. his smptoms 8ill appear 8hen the use

is reduced or stopped.

=erdosage ma cause hpotension, nausea, =omiting, tensed muscle tissue, respiration or circulator

collapse.

PRESENTATIONS :

Lidocaine 5%Injection $us, (0 ampoules > * ml 'eg. +o. : 9L((0*?)5?)?@(

977 I+ 'M 7M7'@A'7 *54?0!BC, '7C E'M LIH

ON MEDICAL PRESCRIPTION ONL

Manufactured " :

-7'+E@'M

/idoarjo 6 Indonesia

'e=ision date : @ugust **nd, *0((

OGB : "at enerik -erno

FOR MORE INFORMATION :

e4mail : info>"ernofarm.com

. -F. )0?G