KUL HISTO RENAL
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7/18/2019 KUL HISTO RENAL
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SISTEMA URINARIA
Ika Fidianingsih
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Copyright © 2008 PearsonEducation, Inc., publishing
as Benjain Cuings
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!
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Copyright ©
2008 Pearson
Education, Inc.,
publishing as
Benjain
Cuings
7/18/2019 KUL HISTO RENAL
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$
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Filtrasi
Filtrat glomeruli Filtrat glomerulussusunan kimianya = plasma darah,tetapi hampir tidak ada protein
Dipengaruhi oleh ! Tekanan hidrostatik
! tekanan osmotik koloid plasma! "omponen kimia plasma darah! #rotein $M% &'(''' Dalton
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Renal corpuscle
)lomerulus and glomerular *apsule
% Glomerulus + tut o *apillaries
&-apillaries o glomerulus arefenestrated
% Glomerular .$o/man0s1 capsule
&#arietal layer + simple s2uamous
epithelium &3is*eral layer + *onsists o
podo*ytes
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#ro4imal tu5ule
% Single layered *u5i* epitelium
& $rush 5order on api*al part
& A5undand mito*hondrias
% Resorption o Na-l and /ater .6'!7891,'lucose, as. (ino transport a)ti*
+a - (P ase
(ir transport pasi* /di*usi
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1#
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Intermedial tu5ule
:enle;s loop% Thin S2uamous *ells, poorly organels
&Descendent part perme5ile or /ater
&As*endent part inpermea5ile or /aterDipengaruhi AD: .permea5le 1
% <u4tamedular nephrons hae long :>
&*ounter*urrent multiplier !hyperosmotic medulla
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Cuin s
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Distal tu5ule
% Single layered *u5i* epitelium
% -ells are lo/er than in pro4imal tu5ule & No 5rush 5order
% Rea5sorption o natrium, se*retion o kalium% ma*ula densa ! *hemore*eptors .-l!1
Dipengaruhi oleh
?(Aldosteron .peningkatan rea5osr5si Na1
@(AD:
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Apparatus Juxtaglomerular
$erungsi mengatur tekanan darah
& Sel Jukstaglomerular + se*rete renin
merupakan modikasi sel otot polos arteri aeren
& Macula densa :% A portion o distal *onoluted tu5ulus,
% Tall, *losely pa*ked epithelial *ells
% A*t as chemoreceptors (deteksiperubahan Na
& Sel Mesangial
ada reseptor Angiotensi !! dan
"asokonstriktor # mempengaruhi $ltrasi
Intrarenal e4*retory
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Intrarenal e4*retorypassages
% -olle*ting tu5ules .Tubullicolligentes1
& Single layered *u5i* epithelium
& Round nu*leus, light *ytoplasm
% #apilar du*ts .Ductus pappilares1
& Single layered *olumnar epithelium
& >ight *ytoplasm
% Regulated /ater rea5sorption .AD:1
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Tu5( -oll
AD: .dise*resi glandula pituitaria1Air .5atas1 AD: dise*resi epitel
permea5el terhadap air
:ormon! Air ⟩⟩ hilang .diare1
AD: dise*resi epithelium
⟩⟩ permea5el
Urine hipertonis
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Intersti*ium
% -onne*ted /ith 5asal lamina o essels andtu5ules
Sel!sel endotel kapiler peritu5uler
menghasilkan eritropoetin1% -orti*al s( medullar
% -ells% Fi5ro5last!like *ells
% -ells /ith lipid droplets% Ma*rophages, peri*ytes
% Non!*ellular elements% proteogly*ans, gly*oproteins, interstitial Buid
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UERETER
% -arry urine rom the kidneys to the urinary5ladder
% C5li2ue entry into 5ladder preents
5a*kBo/ o urine% :istology o ureter
& Mu*osa + transitional epithelium % laminapropia
& Muscularis + t/o layers% Inner longitudinal layer
% Cuter *ir*ular layer
& Ad"entitia +*onne*tie tissue
Mi i St t th
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Mi*ros*opi* Stru*ture o theUreter
Copyright ©2008
Pearson
Education,
Inc.,
publishing
as
Benjain
Cuings
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Urinary 5ladder
% &ransitional epithelium # Mu*osaolded e4*ept o area trigonumesi*ae
% !layered smooth mus*le layer & inner ple4iorm
& middle *ir*ular .→ m( sphin*ter esi*ae1
& outer longitudinal% #art o 5ladder *oered 5y serosa
.peritoneum1
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URETRA
% 'pithelium o urethra & &ransitional epithelium
% At the pro4imal end .near the 5ladder1
& Strati$ed and pseudostrati$ed columnar +
mid urethra .in males1 & Strati$ed suamous epithelium
% At the distal end .near the urethral opening1
% !nternal urethral sphincter & Inoluntary smooth mus*le
% 'xternal urethral sphincter & 3oluntarily inhi5its urination & Rela4es /hen one urinates
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% In emales & >ength o + *m
% In males + @' *m in length + three
named regions & )rostatic urethra
% #asses through the prostate gland
& Membranous urethra
% Through the urogenital diaphragm & Spongy .penile1 urethra
% #asses through the length o the penis
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"elenar #rostat
% 'pitel selapis atau bertingkat torak
menghasilkan *airan prostat G5agiandari semen .enHim proteolik, asam sitart,
asam osatase, 5rinolisis, lemak1
gumpalannnya korpora amilase.glikoprotein yang dapat mengalami
kalsikasi1% Jaringan $broelastis <aringan ikat dan
otot polos
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% Apa per5edaan struktur tu5ulus proksimalisdan distalisJ Mengapa demikianJ
% Sel apakah yang menghasilkan hormonreninJ
% Ansa henle yang mana yang dipengaruhioleh AD:J Apa pengaruhnyaJ
% Epitel permukaan kandung kemiah adalahKK
Apa kekhususan lapisan epitel iniJ
% #lasma darah di ltrasi menuu lumenkapsul 5o/man mele/ati apa saaJ