KSMCB Winter Conference 2016 Time Table

2017

: 2017 1 18()-20() :

The 27th KSMCB Winter Conference 2016 3

Contents

4 6 7

1 20() 8

1 21() 10

1 22() 11

12

13

14

15

31

Gold Ribbon Lecture 31

Blue Ribbon Lectures 31

Old Blue Talks 32

Symposium I 32

Symposium II 33

Young Investigators' Session 34

Poster Presentation I 37

Poster Presentation II 51

Poster Presentation III 65

Author Index 79 Keyword Index 87 Gold/Blue Ribbon Lecturers 95

99

/ 100

101

102

103

4 Korean Society for Molecular and Cellular Biology

2016 (KSMCB Winter Conference 2016)

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Session Grand Ballroom Rainbow Room

1/20 ()

SymposiumI

14:30 ~ 14:55 ()Defensive Function of Human Aminoacyl-tRNA Synthetases against Infection

PosterPresentation

I:14:00~20:00(:17:20~17:50)

14:55 ~ 15:20 ()The Core Pathway of Notch Signaling and Its Posttranslational Regulation

15:20 ~ 15:45 ()Cytomegalovirus Regulation of PML and ISG15-Mediated Innate Immune Responses

15:45 ~ 15:55 Break

15:55~16:20 ()Nucleosome Barrier against Transcription Elongation Is Overcome by Fun30 Chromatin Remodelers

16:20 ~16:45 ()Orphan Nuclear Receptors And Regulation of Innate Immunity

16:45 ~17:10 () Molecular Mechanisms of Osteoarthritis

17:10 ~17:20

17:20 ~19:00 Poster Viewing &

19:00 ~19:30 () Forty Years in Protein Metabolism

Gold Ribbon Lecture

19:30 ~ 20:00 ()Biological Silk Road Consisting of Transporter Proteins

20:00 ~ 20:10

20:10 ~ 20:30 Break

20:30 ~ 21:30 (, )

21:30 ~ 22:00

22:00 ~ () ()

1/21 ()

17:00~19:00 Poster Viewing &

PosterPresentation

II:09:00~21:50(:18:30~19:00)

Blue Ribbon Lectures

19:00~19:25 ()Neural Integration in the Hypothalamic CRF/Dh44 Neuropeptide Neurons

19:25~19:50 () Genome Editing Using Engineered Nucleases

19:50~20:15 ()Regulation of Cytokine RNA Metabolism during Infections

20:15~20:40 ()Molecular Architecture of Polyglutamine Neurodegenerative Disease Protein

20:40~20:50 Break

Old Blue Talks20:50~21:20 () Adipocyte Dysregulation and Insulin Resistance

21:20~21:50 ()Roles of E3 Ligases Regulating Programmed Cell Death

1/22 ()

09:00~09:30 Poster Viewing

PosterPresentation

III:08:30~11:40(:09:00~09:30)

SymposiumII

09:30~09:55 () Opening the Gate of Mammalian Proteasomes and Its Proteostatic Consequences

09:55 ~10:20 () Molecular Mechanisms by Which Paired Plant Immune Receptors Function

10:20 ~10:45 () STAT3-Mediated CD133 Up-Regulation Contributes to Promotion of Hepatocellular Carcinoma

10:45~11:10 () The Genome Seqeuence of Hibiscus syriacus Provides Insights of Genome Polyploidization

11:10~11:15 Break

Young Investigators'

Session

11:15~11:30 () An RNAi Screen Uncovers Small Subunit Processome as Regulator of Pluripotency in Embryonic Stem Cells

11:30 ~11:45 ()

Toll-like Receptor 3 by Exosome Engulfment in Stellate Cells Stimulates Interleukin-17 Production by T Cells in Progression of Liver Fibrosis

11:45~12:00 () Post-Transcriptional Regulation of Drp1 Expression by hnRNP A1

12:00 ~12:15

KSMCB Winter Conference 2016

Time Table


2 7 ()1 20()

13:00 ~ ( 1 )

14:00 ~ 20:00 Poster Presentation I( 1 )

14:30 ~ 15:45 Symposium I()

15:45 ~ 15:55 Break

15:55 ~ 17:10 Symposium I()

17:10 ~ 17:20 ()

17:20 ~ 19:00 Poster Viewing &

19:00 ~ 19:30 ()

19:30 ~ 20:00 Gold Ribbon Lecture()

20:00 ~ 20:10 ()

20:10 ~ 20:30 Break

20:30 ~ 21:30 ()

21:30 ~ 22:00 ()

22:00 ~ () ()

7 ()1 21()

09:00 ~ 21:50 Poster Presentation II()

09:00 ~ 17:00


19:00 ~ 20:40 Blue Ribbon Lectures()

20:40 ~ 20:50 Break

20:50 ~ 21:50 Old Blue Talks()

2 7 ()1 22()

08:30 ~ 11:40 Poster Presentation III()

09:00 ~ 09:30 Poster Viewing

09:30 ~ 11:10 Symposium II()

11:10 ~ 11:15 Break

11:15 ~ 12:00 Young Investigators' Session()

12:00 ~ 12:15 ()


1 20()

Symposium I

: (), () : (), ()

SI-1 14:30 ~ 14:55

Defensive Function of Human Aminoacyl-tRNA Synthetases against Infection ()

SI-2 14:55 ~ 15:20

The Core Pathway of Notch Signaling and Its Posttranslational Regulation ( )

SI-3 15:20 ~ 15:45

Cytomegalovirus Regulation of PML and ISG15-Mediated Innate Immune Responses ( )

15:45 ~ 15:55 Break

SI-4 15:55 ~ 16:20

Nucleosome Barrier against Transcription Elongation Is Overcome by Fun30 Chromatin Remodelers ( )

SI-5 16:20 ~ 16:45

Orphan Nuclear Receptors And Regulation of Innate Immunity ( )

SI-6 16:45 ~ 17:10

Molecular Mechanisms of Osteoarthritis ( )

17:10 ~ 17:20



: () : ()

ML 19:00 ~ 19:30

Forty Years in Protein Metabolism ( )

*2010

.

Gold Ribbon Lecture : () : ()

GL 19:30 ~ 20:00

Biological Silk Road Consisting of Transporter Proteins ( )

60 ( 65 , ) .

20:00 ~ 20:10

20:10 ~ 20:30 Break

20:30 ~ 21:30 (, )

21:30 ~ 22:00 ()

22:00~ () ()


1 21()

Blue Ribbon Lectures : ()

: ()BL-1 19:00 ~ 19:25

Neural Integration in the Hypothalamic CRF/Dh44 Neuropeptide Neurons ( )

BL-2 19:25 ~ 19:50

Genome Editing Using Engineered Nucleases ( )

BL-3 19:50 ~ 20:15

Regulation of Cytokine RNA Metabolism during Infection ( )

BL-4 20:15 ~ 20:40

Molecular Architecture of Polyglutamine Neurodegenerative Disease Protein ( )

40 .

20:40 ~ 20:50 Break

Old Blue Talks

: () : ()

OB-1 20:50 ~ 21:20

Adipocyte Dysregulation and Insulin Resistance ( )

OB-2 21:20 ~ 21:50

Roles of E3 Ligases Regulating Programmed Cell Death ( )

Old Blue Talks .


1 22() Symposium II

: ()

: () SII-1 09:30 ~ 09:55

Opening the Gate of Mammalian Proteasomes and Its Proteostatic Consequences ( )

SII-2 09:55 ~ 10:20

Molecular Mechanisms by Which Paired Plant Immune Receptors Function ( )

SII-3 10:20 ~ 10:45

STAT3-Mediated CD133 Up-Regulation Contributes to Promotion of Hepatocellular Carcinoma ( )

SII-4 10:45 ~ 11:10

The Genome Seqeuence of Hibiscus syriacus Provides Insights of Genome Polyploidization ()

Symposium II (KOBIC) .

11:10 ~ 11:15 Break

Young Investigators' Session

: () : ()

YI-1 11:15 ~ 11:30

An RNAi Screen Uncovers Small Subunit Processome as Regulator of Pluripotency in Embryonic Stem Cells ( RNA )

YI-2 11:30 ~ 11:45

Toll-like Receptor 3 by Exosome Engulfment in Stellate Cells Stimulates Interleukin-17 Production by T Cells in Progression of Liver Fibrosis ( )

YI-3 11:45 ~ 12:00

Post-Transcriptional Regulation of Drp1 Expression by hnRNP A1 ( )

12:00 ~12:15


1. Poster 3 Session .

.

Poster

Session

I P1 - P67 1 20() 14:00 ~ 20:00 17:20 ~ 17:50 1

II P68 - P134 1 21() 09:00 ~ 21:50 18:30 ~ 19:00

III P135 - P201 1 22() 08:30 ~ 11:40 09:00 ~ 09:30

2.

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4. Poster Abstract, Purpose of Experiment, Results ( Figures, Tables),

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6. Poster .

7. Poster .

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: 2016 1 22() 12:00 ~ 12:15,

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Poster Session List


Identification of a novel regulator involved in the Quiescent Center-independent root meristem activity

Goh Choe1, Eun-Sol Kim1, Jose Sebastian3, Linyoung Mao2, Zhangjun Fei2, and Ji-Young Lee1,*1Seoul National University, 2Boyce Thompson Institute for Plant Research, 3Carnegie Institution for Science Department of Plant Biology, Stanford

SND2 and NARS1, NAC domain transcription factors, regulate the phloem development in Arabidopsis roots

Hyou Jin Kim, and Ji-Young Lee*School of Biological Sciences, College of Natural Science, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul 08826, Korea

AMPK-GSK3 Axis Is the Potential Therapeutic Target of Paeonia japonica for the Treatment of Acute Liver Injury

Hae Li Ko, Eun Hye Jung, Jae Kwang Kim, Il Je Cho*, and Sang Chan Kim*MRC-GHF, Department of Herbal Formula, College of Korean Medicine, Daegu Haany University, Gyeongsan 38610, Korea

Aurora A kinase inhibitor leads to mitotic catastrophe in cancer cells

Yoo Hong Min1, and Ja-Eun Kim1,2,*1Department of Biomedical Science, Graduate School, Kyung Hee

University, Seoul 02447, Korea, 2Department of Pharmacology, School of Medicine, Kyung Hee University, Seoul 02447, Korea

Chromatin remodeler Fun30 promotes transcription elongation via modulating nucleosome barrier

Junwoo Lee, and Daeyoup Lee*Department of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejeon, Republic of Korea

Comparative analysis of the silk glands transcriptome between domestic silkworm and wild silkworm

Kwangho Choi*, Seongwan Kim, Jeonghee Yu, Subae Kim, Wansu Kim, and Seongryul KimDepartment of Agricultural Biology, National Institute of Agricultural Science and Technology, RDA, Jeonju 55365, Republic of Korea

Effect as an antioxidant protein of Translationally controlled tumor protein (TCTP) from Arctic copepod Calanus glacialis

Ju-Mi Hong, Yu-Kyung Park, Jung-Eun Kim, Ryeo-Ok Kim, and Il-Chan Kim*Korea Polar Research Institute(KOPRI)

Functional study of O-GlcNAcyaltion on eIF2 under ER stress condition

Insook Jang1, Han Byeol Kim1, Hojoong Seo1, Jin Young Kim2, Hyeonjin Choi3, Jong Shin Yoo2, Jae-woo Kim4, and Jin Won Cho1,*1Department of Integrated OMICS for Biomedical Science, Yonsei University, Seoul 120-749, Republic of Korea,

2Division of Mass

Spectrometry Research, Korea Basic Science Institute, 162 Yeongudanjiro, Ochang, Cheongju 363-883, Republic of Korea, 33Department of Biochemistry and Molecular Biology, Integrated

Genomic Research Center for Metabolic Regulation, Institute of Genetic Science, Yonsei University College of Medicine, Seoul 120-749, Republic of Korea,

4Brain Korea 21 LUS Project for

Medical Science, Yonsei University, Seoul 120-749, Republic of Korea

Longevity conferred by collaboration between HEL-1/RNA helicase and DAF-16/FOXO transcription factor in C. elegans

Mihwa Seo1,2,4,5, Keunhee Seo1, Wooseon Hwang1, Hee Jung Koo2,4,5, Jeong-Hoon Hahm4, Jae-Seong Yang2, Seong Kyu Han1, Daehee Hwang4,5, Sanguk Kim1,2,3, Sung Key Jang1, Yoontae Lee1, Hong Gil Nam4,5,*, and Seung-Jae Lee1,2,3,*Department of Life Sciences, Pohang University of Science and Technology, 2School of Interdisciplinary Bioscience and Bioengineering,

3Information Technology Convergence

Engineering, Pohang, Gyeongbuk, South Korea, 4Center for Plant Aging Research, Institute for Basic Science, 5Department of New Biology, Daegu Gyeongbuk Institute of Science and Technology, Daegu

Cloning and characterization of a new antimicrobial peptide gene from Papilio xuthus

Seong-Ryul Kim1,*, Kwang-Ho Choi1, Su-Bae Kim1, Seong-Wan Kim1, and Seung-Won Park21Department of Agricultural Biology, National Academy of Agricultural Science, RDA, 2Department of Biotechnology, Catholic University of Daegu

Elevated O-GlcNAc modification under hypoglycemia relates with EMT in breast cancer cells

Eunah Kim, and Jin Won Cho*Dept. of Integrated OMICS for Biomedical Sciences, WCU pro-gram of Graduate School, Yonsei university

Generation of obesity-induced type 2 diabetes mouse models using the CRISPR-Cas9 system

Seong Uk Park1, Jae-il Roh1, Young Jin1, Na Young Ha2, Ji-Young Cha3, and Han-woong Lee1,2,*1Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul, Korea, 2Yonsei Laboratory Animal Research Center, Yonsei University, Seoul, Korea, 3Gachon Medical Research Institute, Gil Hospital, Incheon, Korea

Synthesis and antimicrobial activity of hybrid peptide, PTD-PAPI

Su-Bae Kim, Seong-Wan Kim, Kwang-Ho Choi, and Seong-Ryul Kim*Department of Agricultural Biology, National Academy of Agricultural Science, RDA

14-3-3g-Mediated Surface Expression of ANO1 Regulates Cancer Progression of Glioblastoma Cells

Young Sun Lee1,2, Yeon-ju Bae1, Chang-Hoon Cho1, Kang-Hyun Ryoo1, and Jae-Yong Park1,*1School of Biosystem and Biomedical Science, College of Health

Science, Korea University, 2Department of Anatomy and Neurobiology, Institute of Health Sciences, School of Medicine, Gyeongsang National University

A Study on How O-GlcNAcase Translocates into Nucleus

Yeon Jung Kim, and Jin Won Cho*Department of integrated OMICS for Biomedical Science, Yonsei University

Akt1 down regulates gamma-secretase activity through phosphorylation and degradation of NCT

Eun-Hye Jo, Mi-Yeon Kim, Eun-Jung Ann, Ji-Hye Yoon, Ji-Seon Ahn, Hye-Jin Lee, Se-Hoon Hong, Nam-Young Kim, and Hee-Sae Park*Hormone Research Center, School of Biological Sciences and Technology, Chonnam National University, Gwangju, Republic of Korea

P-1

P-2

P-3

P-4

P-5

P-6

P-7

P-8

P-9

P-10

P-11

P-12

P-13

P-14

P-15

P-16


Alpha-synuclein negatively regulates Notch1 signaling through Fbw7-mediated Notch1-IC destabilization

Ji-Seon Ahn, Mi-Yeon Kim, Eun-Jung Ann, Ji-Hye Yoon, Eun-Hye Jo, Hye-Jin Lee, Se-Hoon Hong, Nam-Young Kim, and Hee-Sae Park*Hormone Research Center, School of Biological Sciences and Technology, Chonnam National University, Gwangju, Republic of Korea

An Analysis of the Distribution of Single Nucleotide Polymorphism in Rice Genome

Byoung-Kook Yun, JinHee Park, Jung-A Kim, and Chang-Yong Lee*Department of Industrial and Systems Engineering, Kongju National University, Cheonan, 31080, Korea

Anti-allergic Effect of Eupatilin through the Regulation of Inflammation in vivo and in vitro

Eun-Hye Song, Kyung-Sook Chung, and Hyo-Jin An*Department of Pharmacology, College of Oriental Medicine, Sangji University, Wonju-si, Gangwon-do 220-702, Republic of Korea

C. elegans elongin C regulates longevity and proteostasis through hypoxia-inducible factor 1

Wooseon Hwang1, Murat Artan2, Mihwa Seo3,4, Dongyeop Lee1, Hong Gil Nam4,5, and Seung-Jae V. Lee1,2,3,*1Department of Life Sciences, Pohang University of Science and Technology, Pohang, Gyeongbuk, South Korea,

2Information

Technology Convergence Engineering, Pohang University of Science and Technology, Pohang, Gyeongbuk, South Korea, 3School of Interdisciplinary Bioscience and Bioengineering,

Pohang University of Science and Technology, Pohang, Gyeongbuk, South Korea, 4Center for Plant Aging Research, Institute for Basic Science, Daegu, South Korea,

5Department of

New iology, DGIST, Daegu, South Korea

C. elegans kinase-4 promotes PTEN-dependent longevity through PDZ domain-mediated physical interaction

Seon Woo A. An1,4, Eunseok Choi1,4, Jae-Seong Yang2, Keunhee Seo1, Wooseon Hwang1, Heehwa G. Son1, Hyun-Jun Nam2, Sanguk Kim1,2,3, and Sueng-Jae V. Lee1,2,3,*1Department of Life Sciences, 2IBIO, 3ITCE, Pohang University of Science and Technology, Pohang, Gyeongbuk, 790-784, South Korea,

4These authors contributed equally to this work

Cell Wall-associated ROOT HAIR SPECIFIC 10, a Pro-rich Reeptor-like Kinase, is a Negative Modulator for Arabidopsis Root Hair Growth

Youra Hwang, Hyung-Taeg Cho*, Hyodong Lee, and Young-Sook LeeDepartment of Biological Sciences, Seoul National University, Seoul 151-742, Korea

Characterization of the silkglands-specific expressed gene of silkworm

Jeong Hee Yu, Seong-Wan Kim, Su-Bae Kim, Wan-Su Kim, Seong-Ryul Kim, and Kwang-Ho Choi*Sericultural & Apicultural Materials Division, National Academy of Agricultural Science, RDA, 166, Nongsaengmyeong-ro, Iseo-myeon, Wanju-gun, Jeollabuk-do 55365, Korea

Comparison of nucleocapsid (N)protein-and spike (S) protein-based serological assays in patients with Middle East respiratory syndrome(MERS)

Sun-Mi Kim1, Beak-Nam Kim2, Jee-Young Lee3, and Sung-Han Kim1,*1Department of Infectious Diseases, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea, 2Department of Internal Medicine, Inje University Sanggye-Paik Hospital, Seoul, Rebulic of Korea, 3Division of Infectious Diseases, Department of Internal Medicine, Dankook University Hospital, Dankook University College of Medicine, Cheonan, Republic of Korea

CRTC3 Regulates Glucose Homeostasis through Modulating XBP1s and FOXO1

Janghyuk Ju, Seri Choi, and Seung-Hoi Koo*Division of Life Sciences, College of Life Sciences and Biotechnology, Korea University, 02841, Anam-Ro 145, Seongbuk-Gu, Seoul, Korea

Development of a new recombinant protein expression system in insect cell

Seong Wan Kim1, Jeong Hee Yu1, Su-Bae Kim1, Seong Ryul Kim1, Tae-Won Goo2, and Kwang-Ho Choi1,*1Department of Agricultural Biology, National Academy of Agricultural Science, RDA,

2Department of Biochemistry, School

of Medicine, Dongguk University of Gyeongju

Down-regulation of Jagged1 signaling by Fe65 through the E3 ligase Neuralized-like 1

Hye-Jin Lee, Eun-Jung Ann, Ji-Hye Yoon, Ji-Seon Ahn, Eun-Hye Jo, Se-Hoon Hong, Nam-Young Kim, Mi-Yeon Kim, and Hee-Sae Park*Hormone Research Center, School of Biological Sciences and Technology, Chonnam National University, Gwangju, Republic of Korea

Effect of Pachymic Acid on Autophagy in WI38 cells

Su-Gyeong Lee, ChaeEun Song, EunBeen Lee, and Moon-Moo Kim*Department of Chemistry, Dong-Eui University, Busan 614-714, Republic of Korea

Effect of -Caryophyllene Oxide on Activity and Expression of Proteins Related to Metastasis

Sugyeong Hong, Hyejeong Kim, Sung beom Park, and Moon-Moo Kim*Department of Chemistry, Dong-Eui University, Busan 614-714, Republic of Korea

Efficient and rapid cellular delivery of bioactive proteins using EXPLOR: exosomes engineered for protein loading via optically reversible proteinprotein interactionNambin Yim1, Seung-Wook Ryu1, Kyungsun Choi1, Kwang Ryeol Lee1, Seunghee Lee1, Hojun Choi1, Ji-Ho Park1, Jeongjin Kim2, Daesoo Kim2, Won Do Heo2, and Chulhee Choi1,*1Department of Bio and Brain Engineering, KAIST, 2Department of Biological Sciences, KAIST

Enhancing Neuronal maturation by Artemisia annua administration in the animal model

Hye Kyung Baek1, Ji Ae Song1, Sung Jo Kim2, and Sun Shin Yi1,*1Department of Biomedical Laboratory Science, Soonchunhyang

University, Asan, Korea, 2Department of biotechnology, Hoseo University, Asan, Korea

Ethanol Extract of Aster Glehni Inhibits Colonic Inflammatory Responses in DSS-induced Colitis Mice Models via NF-B Inactivation

Jun-Hyeok Choi, Kyung-Sook Chung, Jeong-hoon Ahn, and Hyo-Jin An*Department of Pharmacology, College of Oriental Medicine, Sangji University, Wonju-si, Gangwon-do 220-702, Republic of Korea

Expansin-mediated Cell Wall Modification System to Understand the Mechanism from Cell Wall Dynamics to Cellular Processes

Hydong Lee, and Hyung-Taeg Cho*Department of Biological Sciences, Seoul National University, Seoul, Korea

Functional Conservation and Diversification of the M3 Phosphorylation Site of PIN-FORMEDs for their Polarity and Biological Roles in Arabidopsis

P-17

P-18

P-19

P-20

P-21

P-22

P-23

P-24

P-25

P-26

P-27

P-28

P-29

P-30

P-31

P-32

P-33

P-34

Poster Session List


Daeeun Ki1, Daisuke Sasayama1,2, and Hyung-Taeg Cho1,*1Department of Biological Sciences, Seoul National University,

Seoul 151-742, Korea, 2Organization of Advanced Science and Technology, Kobe University, 1-1 Rokkodai-cho, Nada-ku, Kobe, Hyogo 657-8501, Japan

Generation of immune-deficient mouse models for human diseases

Yu Jin Kim1, Jaehoon Lee1, Na-Yeong Ha2, Jung Ah Hong1, Ji Eun Kang1, Yang-Kyu Choi3, and Han-Woong Lee1,2,*1Department of Biochemistry, College of Life Science and

Biotechnology, Yonsei University, Seoul 120-749, South Korea, 2Yonsei Laboratory Animal Research Center, Yonsei University, Seoul 120-749, South Korea,

3Department of Laboratory Animal

Medicine, College of Veterinary Medicine, Konkuk University, Seoul 143701, Republic of KoreaHepatic Stellate Cell-Derived Retinoic Acids Enhance the Maturity of Hepatocyte-Like Cells in Drug Metabolism

Hyuk Soo Eun, Wonhyo Seo, and Won-il Jeong*Korea Advenced Institute of Science and Technology

HIPK2 phosphorylates Notch1 and facilitates its degradation by Fbw7 ubiquitin ligase

Eun-Jung Ann, Mi-Yeon Kim, Ji-Hye Yoon, Ji-Seon Ahn, Eun-Hye Jo, Hye-Jin Lee, Se-Hoon Hong, Nam-Young Kim, and Hee-Sae Park*Hormone Research Center, School of Biological Sciences and Technology, Chonnam National University, Gwangju, Republic of Korea

Identification of the nuclear localization signal of O-GlcNAc transferase and its nuclear import regulation

Hyeon Gyu Seo1, Han Byeol Kim1, Min Jueng Kang2, Joo Hwan Rym1, Eugene C. Yi2, and Jin Won Cho1,*1Department of Integrated OMICS for Biomedical Science, Graduate School, Yonsei University, 50 Yonsei-ro, Seodaemun-gu, Seoul 03722, Republic of Korea,

2Department of Molecular

Medicine and Biopharmaceutical Sciences, School of Convergence Science and Technology and College of Medicine or College of Pharmacy, Seoul National University, 28 Yeongeon-dong, Jongno-gu, Seoul 03080, Republic of Korea

Interaction between mitsugumin 29 and TRPC3 participates inregulating Ca

2+ transients in skeletal

muscle

Jin Seok Woo1, Ji-Hye Hwang1, Mei Huang1, Mi Kyoung Ahn1, Chung-Hyun Cho2, Jianjie Ma3, and Eun Hui Lee1,*1Department of Physiology, College of Medicine, The Catholic University of Korea, Banpo-daero 222, Seocho-gu, Seoul 137-701, Republic of Korea,

2Department of Pharmacology, College of

Medicine, Seoul National University, Seoul 110-799, Republic of Korea, 3Department of Surgery, Davis Heart and Lung Research Institute, The Ohio State University, Columbus, OH 43210, USA

Intranuclear Interactomic Inhibition of NF-B Suppresses LPS-induced Severe Sepsis

Sung-Dong Park1,2, So Yeong Cheon3, Tae-Yoon Park1,2, Bo-Young Shin1,2, Hyunju Oh4, Sankar Ghosh4, Bon-Nyeo Koo3,*, and Sang-Kyou Lee1,2,*1Translational Research Center for Protein Function Control,

College of Life Science and Biotechnology, Yonsei University, Seoul 120-749, Republic of Korea, 2Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul 120-749, Republic of Korea, 3Department of Anesthesiology and Pain Medicine, Anesthesia and Pain Research Institute, Yonsei University College of Medicine, Seoul 120-752, Republic of Korea, 4Department of Microbiology and mmunology, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA

Investigation on antibacterial activity of Dendropanx morbifera Levill extract

Seungbin Cha, Kwonseong Kim, R. Harikishna Reddy, and Youngjun Kim*Department of Applied Biochemistry, Konkuk University,

Chungju, 27478, Korea

Is OCT compound solution really necessary to cyrosectioning of Brain using with Cyrostat?

Hye Kyung Baek, Ji Ae Song, and Sun Shin Yi*Department of Biomedical Laboratory Science, Soonchunhyang University, Asan, Korea

KIF5B-RET fusion gene may induce EMT via the regulation of two transcription factors, FOXA2 and STAT5A

Min-Young Kim1, Jung-Young Shin2, Jeong-Oh Kim3, Kyoung-Hwa Son4, and Jin Hyoung Kang5,*1The Catholic University of Korea, Seoul,

2The Catholic

University of Korea, Seoul, 3The Catholic University of Korea, Seoul, 4The Catholic University of Korea, Seoul, 5The Catholic University of Korea, Seoul

Lipid-overloaded Enlarged Adipocytes Provoke Insulin Resistance Independent of Inflammation

Jong In Kim1, Jin Young Huh1, Jee Hyung Sohn1, Sung Sik Choe1, Chun Yan Lim2, Ala Jo3, Seung Bum Park3, Weiping Han2, and Jae Bum Kim1,*1School of Biological Science, Institute of Molecular Biology and

Genetics, Seoul National University, Seoul 151-742, Korea, 2Laboratory of Metabolic Medicine, Singapore Bioimaging Consortium, Agency for Science, Technology and Research (A*STAR), Singapore 138667, Singapore, 3Deparment of Chemistry, Seoul National University, Seoul 151-747, Korea

Lipoproteins in cord serum from small-for-gestational-age neonates and Ex-smokers breast milk show dysfunctional properties: A clue for Barkers hypothesis

Seong-Min Kim, and Kyung-Hyun Cho*Dept of Medical Biotechnology, Yeungnam University, Gyeongsan, 712-749, Republic of Korea

Long Lifespan Correlates with Slow Growth among Wild C. elegans Strains

Yujin Lee1,6, Wooseon Hwang1,6, Juyoung Jung1, Sangsoon Park1, Josephine Jill T. Cabatbat4, Pan-Jun Kim4,5, and Seung-Jae V. Lee1,2,3,*1Department of Life Sciences,

2School of Interdisciplinary

Bioscience and Bioengineering, 3Information Technology Convergence Engineering, Pohang University of Science and Technology, Pohang, Gyeongbuk, South Korea,

4Asia Pacific

Center for Theoretical Physics, Pohang, Gyeongbuk, South Korea, 5Department of Physics, Pohang University of Science and Technology, Pohang, Gyeongbuk, South Korea,

6These authors

contributed equally to this work.*Crresponding author: [email protected]

MiroRNA Connection in BRAF Inhibitor-induced Acquired Resistance of Malignant Melanoma

Jae-Hyeon Kim, and Michael Lee*Division of Life Sciences, College of Life Sciences and Bioengineering, Incheon National University, Incheon 406-772, Republic of Korea

Mitochondrial Chaperone HSP-60 Enhances Anti-bacterial Immunity via Up-regulation of p38 MAP Kinase in C. elegans

Dae-Eun Jeong1, Dongyeop Lee1, Sun-Young Hwang1, Yujin Lee1, Mihwa Seo2, Wooseon Hwang1, Keunhee Seo1, Ara Hwang1, Murat Artan3, Heehwa Son1, Haeshim Baek1, Young-Min Oh1, Joo-Yeon Yoo1,*, and Seung-Jae V. Lee1,2,3,*Department of Life Sciences, POSTECH, Pohang, Gyeongbuk, South Korea, 2I-BIO, POSTECH, Pohang, Gyeongbuk, South Korea,

3WCU ITCE, POSTECH, Pohang, Gyeongbuk, South

Korea

The traditional herbal medicine Ga-Gam-Nai-Go-Hyan suppresses testosterone-induced benign prostatic hyperplasia by regulating inflammatory responses and apoptosis

Su-Jin Shin, Kyung-Sook Chung, Jin-Hong Jeon, and

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Hyo-Jin An*Department of Pharmacology, College of Oriental Medicine, Sangji University, Wonju-si, Gangwon-do 220-702, Republic of Korea

Musulju Improves Benign Prostatic Hyperplasia by Regulating Inflammatory and Apoptotic Proteins

Se-Yun Cheon, Kyung-Sook Chung, and Hyo-Jin An*Department of Pharmacology, College of Oriental Medicine, Sangji University, Wonju-si, Gangwon-do 220-702, Republic of Korea

Nonsense-mediated Decay Enhances RNA Homeostasis and Longevity Caused by Reduced Insulin/IGF-1 Signaling in C. elegans

Heehwa G. Son1, Mihwa Seo1,2,7, Seokjin Ham4, Wooseon Hwang1, Murat Artan3, Seon Woo A. An1, Keunhee Seo1, Rachel L. Kaletsky5, Yoon Ki Kim6, Coleen T. Murphy5, Tae-Young Roh4, Hong Gil Nam7,8,*, and Seung-Jae V. Lee1,2,3,*1Department of Life Sciences,

2School of Interdisciplinary

Bioscience and Bioengineering, 3Information Technology Convergence Engineering, Pohang University of Science and Technology,

4Integrative Bioscience and Bioengineering, Pohang

University of Science and Technology Pohang, Gyeongbuk, South Korea, 5Department of Molecular Biology & LSI Genomics, Princeton University, Princeton, NJ 08544, USA,

6Division of Life

Sciences, Korea University, Seoul 136-701, Republic of Kore, 7Center for Plant Aging Research, Institute for Basic Science, 8Department of New Biology, Daegu Gyeongbuk Institute of

Science and Technology, Daegu

NOTCH1 intracellular domain regulates PAK1 nuclear translocation

Ji-Hye Yoon, Mi-Yeon Kim, Eun-Jung Ann, Ji-Seon Ahn, Eun-Hye Jo, Hye-Jin Lee, Se-Hoon Hong, Nam-Young Kim, and Hee-Sae Park*Hormone Research Center, School of Biological Sciences and Technology, Chonnam National University, Gwangju, Republic of Korea

Nrf2 Activation by Rosa laevigata Michx. Protects Hepatocytes from Arachidonic Acid and Iron-Mediated Oxidative Stress

Kyung Hwan Jegal, Hae Li Ko, Sang Mi Park, Ji Yun Jung, Gyu Pyo Noh, Il Je Cho*, and Sang Chan Kim*MRC-GHF, Department of Herbal Formula, College of Korean Medicine, Daegu Haany University, Gyeongsan 38610, Korea

Change of O-GlcNAcylation is the regulator of autophagy in Drosophila melanogaster

Jin Won Pak, Sujin Park, and Jin Won Cho*Department of Integrated OMICS for Biomedical Science, Graduate School, Yonsei University

O-GlcNAc modification of NF-B induces the severity of Rheumatoid Arthritis through TNF- mediated inflammation

Han Byeol Kim1, Sang-Won Lee2, Chin Hee Mun2, Ji Young Yoon1, Jaeyoung Pai3, Injae Shin3, Yong-Beom Park2, Soo-Kon Lee2,*, and Jin Won Cho1,*1Department of Integrated OMICS for Biomedical Science,

Graduate School, Yonsei University, 22Division of Rheumatology, Department of Internal Medicine, Yonsei University College of Medicine,

33Department of Chemistry, Yonsei University

p204: A Dual Modulator against Pathogen Infection in Macrophage-Mediated Innate Immunity

Young-Su Yi*, Elena Gonzalez-gugel, and Chuanju Liu*Department of Orthopaedic Surgery, Hospital for Joint Diseases, New York University Medical Center, New York, NY 10003 USA

Paclitaxel Exerts Its Effects through the Up-regulation of p27

Kip1 Expression in Glioma Cell

Lines with Wild Type p53

Byeal-I Han, and Michael Lee*Division of Life Sciences, College of Life Sciences and

Bioengineering, Incheon National University, Incheon 406-772, Republic of Korea

Rice hull extract (RHE) suppress differentiation of preadiopocytes to adipocytes via AMPK pathways

Ga-Hee Kim, Kyung-Sook Chung, and Hyo-Jin An*Department of Pharmacology, College of Oriental Medicine, Sangji University, Wonju-si, Gangwon-do 220-702, Republic of Korea

SREBP/MDT-15 Transcription Factor Complex Moderates Toxic Effects of Glucose on Lifespan by Reducing Saturated Fat in C. elegans

Dongyeop Lee1, Dae-Eun Jeong1, Heehwa G Son1, Yasuyo Yamaoka1, Hyunmin Kim5, Keunhee Seo1, Abdul Aziz Khan4, Tae-Young Roh1,4, Dae Won Moon5, Youngsook Lee1, and Seung-Jae V Lee1,2,3,*1Department of Life Sciences, Pohang University of Science and Technology, Pohang, Gyeongbuk, South Korea,

2Information

Technology Convergence Engineering, Pohang University of Science and Technology, Pohang, Gyeongbuk, South Korea, 3School of Interdisciplinary Bioscience and Bioengineering,

Pohang University of Science and Technology, Pohang, Gyeongbuk, South Korea, 4Division of Integrative Biosciences and Biotechnology, Pohang University of Science and Technology, ohang, Gyeongbuk, South Korea, 5Department of New Biology, Daegu Gyeongbuk Institute of Science and Technology, Daegu, South Korea

STAT3-mediated CD133 upregulation contributes to promotion of hepatocellular carcinoma

Byung-Hak Kim1,2, Yong-Jin Kwon1, Song-Hee Lee1, Kum Hee Noh1, Sunho Kwon1, Ae Jin Jeong1, Haeri Lee1, Eun Hee Yi1,2, and Sang-Kyu Ye1,2,*1Department of Pharmacology, Seoul National University College of Medicine, 2Biomedical Science Project (BK21PLUS), Seoul National University College of Medicine

Surface Expression of Anoctamin-1 (ANO1) Channel is Attenuated by Protein-Protein Interaction with -COP

Young-Sun Lee1,2, Yeon-Ju Bae2, Jae Cheal Yoo2, and Jae-Yong Park2,*1Department of Neurobiology, Institute of Health Science, and

Medical Research Center for Neural Dysfunction, Gyeongsang National University School of Medicine, 2School of Biosystem and Biomedical Science, College of Health Science, Korea University

Synergistic effect of combined cdk4/6 inhibitor with docetaxel in lung cancer cell lines harboring KRAS mutations

Kyoung hwa Son1, Jung Young Shin2, Jeong oh Kim3, Min Young Kim4, and Jin Hyoung Kang5,*1The catholic university of Korea, Seoul, Korea, 2The catholic uni-versity of Korea, Seoul, Korea, 3The catholic university of Korea, Seoul, Korea,

4The catholic university of Korea, Seoul, Korea,

5The catholic university of Korea, Seoul, Korea*Coresponding author: [email protected]

The Alangium alkaloid tubulosine as a selective JAK3 inhibitor for the treatment of leukemia and lymphoma

Byung-Hak Kim1,2, Yong-Jin Kwon1, Song-Hee Lee1, Kum Hee Noh1, Sunho Kwon1, Ae Jin Jeong1, Haeri Lee1, Eun Hee Yi1,2, and Sang-Kyu Ye1,2,*1Department of Pharmacology, Seoul National University College of Medicine,

2Biomedical Science Project (BK21PLUS), Seoul

National University College of Medicine

The Inhibitory Effect of Nodakenin on Mast Cell Mediated Allergic Responses

Na Young Lee, Kyung-Sook Chung, and Hyo-Jin An*Department of Pharmacology, College of Oriental Medicine, Sangji University, Gangwon-do 220-702, Republic of Korea

The role of Krebs cycle metabolites in innate immunity of C. elegans

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Poster Session List


Yujin Lee1, Dae-Eun Jeong1, Dongyeop Lee1, and Seung-Jae V. Lee1,2,3,*1Department of Life Sciences, 2Information Technology Convergence Engineering,

3School of Interdisciplinary Bioscience

and Bioengineering, Pohang University of Science and Technology

Trichinella spiralis Infection modulated host intestinal environments through gut microbiota

Shine ae Kang1,2, Jun ho Choi1,2, Da in Lee1,2, So myong Song1,2, and Hak sun Yu1,*1Department of Parasitology, School of Medicine, Pusan National University,

2Immunoregulatory therapeutics group in Brain Busan

21 project, Yangsan, Korea

TWIK1-TASK3 heterodimerization contributes to High resting membrane potential of Dentate gyrus granule cells

Jae Hyouk Choi1,2, Oleg Yarishkin1, Young sun Lee3, Jae-Yong Park3, and Eun Mi Hwang1,2,*1Center for Functional Connectomics, Korea Science and Technology, Seoul, 136-791, Republic of Korea, 2Neuroscience Program, University of Science and Technology (UST), Daejeon, Republic of Korea, 3School of Biosystem and Biomedical Science, College of Health Science, Korea University, Seoul 136-703, Republic of Korea

A monoclonal antibody against glycosylation on cell surface of the undifferentiated human dental pulp stem cells

yung-Jung Kang, and Young-Joo Jang*Department of Nanobiomedical Science & BK21 PLUS Global Research Center for Regenerative Medicine, Dankook University, 330-714, Korea

A neurokine that stimulates formyl peptide receptor 2

Min Young Park1, Ha Young Lee1, Hyung Sik Kim1, Ye Seon Kim1, Jae Young Seong2, and Yoe-Sik Bae1,3,*1Department of Biological Sciences, Sungkyunkwan University, Suwon, Republic of Korea,

2Graduate School of Medicine, Korea

University, Seoul, Republic of Korea, 3Department of Health Sciences and Technology, SAIHST, Sungkyunkwan University, Seoul, Republic of Korea

A sRNA Spot 42 induces Rho-termination in E. coli

Xun Wang, Sang Chun Ji, Heung Jin Jeon, Yonho Lee, and Heon M Lim*Department of Biological Sciences, College of Biological Sciences and Biotechnology, Chungnam National University, Daejeon 305-764, Republic of Korea

Wnt3a Prevents Hot-spot Formation on the PPARg2 Promoter

Bongju Park, and Hyunsung Park*Department of Life Science, University of Seoul, Siripdae-gil 13, Dongdaemun-gu, Seoul 130-743, Korea

Carbon Monoxide Prevents Acetaminophen-Induced Hepatotoxicity via regulation of reactive oxygen species

Hyeok-Jun Park1, Yingqing Chen1, Jeongmin Park1, Yeonsoo Joe1, Hyo Jeong Kim1, Se-Ung Park1, Sena Kim1, Jeong Woo Park1, Jaekyoon Shin2, and Hun Taeg Chung1,*1Meta-inflammation Basic Research Laboratory, School of

Biological Sciences, University of Ulsan, Ulsan, Korea, 2Department of Molecular Cell Biology, Sungkyunkwan University School of Medicine, Suwon 440-746, South Korea

Comprehensive Characterization of Human Polarized Macrophages

Seol-Hee Kim1, Dae-Won Kim2, TaeSoo Kwon2, Hyerin Kim1, and Sook-Kyung Kim1,*1Center for Bioanalysis, Division of Metrology for Quality of Life,

Korea Research Institute of Standards and Science, Daejeon 305-340, Korea, 2Department of Biosafety Evaluation & Control, Korea National Institute of Health, Chungbuk 363-951, Korea

Dissection of AHL4 protein in its intercellular trafficking and vascular tissue patterning

Minji Seo1, Kook Hui Ryu1, Jing Zhou2, and Ji-Young Lee1,2,*1School of Biological Sciences, Seoul National University, Seoul

Korea 151-747, 2Boyce Thompson Institute for Plant Research, Tower Rd. Ithaca NY U.S.A 14853

Effects of Novel Synthetic GPR119 Agonists on Enteroendocrine L-cell and Pancreatic -cell

Jung Seok Kim1, Jung Jae Shin1, Jun Gi Rho1, Sungeun Heo1, Yong Jae Lee2, and Wook Kim1,*1Department of Molecular Science and Technology, Ajou University, Suwon, 442-721, South Korea,

2Department of

Pharmacology, Chong Kun Dang Research Institute, Yongin, 446-916, South Korea

Effects of Silkworm Extract on the Adipogenic Differentiation in 3T3-L1 Cells

So-Eun Park1, Gwang-Ho Choi2, Seong Ruyl Kim2, TaeWon Goo3, and Seung-Won Park1,*1Department of Biotechnology, Catholic University of Daegu, Daegu 712-702,

2Sericultural and Apicultural Materials Division,

National Academy of Agricultural Science, RDA, Wanju 565-851, 3Department of Biochemistry, Dongguk University College of Medicine, Gyeongju 780-714, Republic of Korea

Effects of Ziprasidone on Neuronal Loss and Changes of MFG-E8-immunopositive Cells of the Infarct after Transient Focal Cerebral Ischemia in Rats

Yong-Won Choi1, and Kyung-Yoon Kam2,*1Dept. of Rehabilitation Science, Inje University,

2Dept. of

Occupational Therapy, Inje University

Identification of anti-neuroinflammatory effect of plant P methanol extract in LPS-stimulated BV-2 microglia cells

Shin-Young Park1, Jeong-In Park1, Duk-Yeon Cho1, Seo-Young Shin2, Hyae-Shin Lee2, Hyun-Myung Ko2, and Dong-Kug Choi1,2,*1Department of Applied Life Science, BK21plus Glocal Education program of of Nutraceuticals Development, Konkuk University, Chungju 27478, Korea,

2Department of Biotechnology, College of

Biomedical and Health science, Konkuk Univarsity, Chungju 380-701, Korea*Correspoding author: [email protected]

Identification of Novel Inhibitors of Dual Specificity Phosphatase 15

Hwangseo Park1, Hye Seon Lee2,3, and Seung Jun Kim2,*1Department of Bioscience and Biotechnology, Sejong University;

209 Neungdong- ro, Kwangjin-gu, Seoul 143747, Korea, 2Functional Genomics Research Center, Korea Research Institute of Bioscience and Biotechnology; 125 Gwahak-ro, Yuseong-gu, Daejeon 305806, Korea, 3Department of Biology, Chungnam National University 99 Daehak-ro, Yuseong-gu, Daejeon 305-764, Korea

Pterostilbene 4-glucoside Attenuates LPS-induced Acute Lung Injury through Induction of Heme Oxygenase-1

Se-Ung Park1, Jeongmin Park1, Yingqing Chen1, Yeonsoo Joe1, Hyo Jeong Kim1, Hyeok-Jun Park1, Sena Kim1, Jeong Woo Park1, Jaekyoon Shin2, and Hun Taeg Chung1,*1Meta-inflammation Basic Research Laboratory, School of

Biological Sciences University of Ulsan, Ulsan, Korea, 2 Department of Molecular Cell Biology, Sungkyunkwan University School of Medicine, Suwon 440-746, South Korea

Spider Venom PnTx2-6 Recombinant Protein Expression and Potentiates Vascular Tone

Ji Min Noh1, Gwang-Ho Choi2, Seong Ryul Kim2, TaeWon Goo3, and Seung-Won Park1,*1Department of Biotechnology, Catholic University of

Daegu,Daegu 712-702, 2Sericultural and Apicultural Materials Division, National Academy of Agricultural Science, RDA, Wanju 565-851,

3Department of Biochemistry, Dongguk University

College of Medicine, Gyeongju 780-714, Republic of Korea

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SUMOylation of TBL1-TBLR1 promotes NF-B-mediated cytokine production in androgen-independent prostate cancer cells

Hyo-Kyoung Choi1, Jin-Taek Hwang1, Soo-Yeon Park2, and Ho-Geun Yoon2,*1Korea Food Research Institute, 1201 Anyangpangyoro,

Bundang-gu, Seongnam- si, Gyeonggi-do 463-746, Republic of Korea, 2Department of Biochemistry and Molecular Biology, Yonsei University College of Medicine, 134 Shinchon-dong, Seodaemun-gu, Seoul, Republic of Korea

A neuropeptide Allatostatin-C Regulates Two Distinct Processes of Egg-laying in Drosophila

Chen Zhang, Yong-Hoon Jang, and Youn-Joon Kim*School of Life Sciences, Gwangju Institute of Science and Technology, Gwangju 500-712, Republic of Korea

A pair of the Uterine Neurons Important for the Sex-peptide Independent Post-mating Behavioral Switch in Female Drosophila

Hyo-Seok Chae, Yong-Hoon Jang, and Young-Joon Kim,*School of Life Sciences, Gwangju Institute of Science and Technology, Gwangju 500-712, Republic of Korea

A role of Cps35/Swd2 for the mechanism of histone H2B monoubiquitination-dependent H3K4 trimethylation

Shinae Park, Jun-Soo Oh, and Jung-Shin Lee*Molecular Biochemistry Lab, Department of Molecular Bioscience, College of Biomedical Science, Kangwon National University, 1 Kangwondaehak-gil, Chuncheon-si, Gangwon-do, 200-701 Republic of Korea

Anti-Inflammatory Effects of Methanol Extract of Ficus vasculosa on Lipopolysaccharide-Induced NF-B Activation in Raw264.7 Macrophage Cell

Ji-Won Park1,2, Ok-Kyoung Kwon1,3, Han-Sol Lee1, YouRim Lim1, Sei-Ryang Oh1, Jae-Hong Kim2, and Kyung-Seop Ahn1,*1Natural Medicine Research Center, Korea Research Institute of

Bioscience and Biotechnology, Chungbuk 363-883, Korea, 2College of Life Sciences and Biotechnology, Korea University, Seoul 136-701, Korea,

3Department of Toxicology, College of

Pharmacy, Chungnam National University, Daejeon, Korea

Anti-neuroinflammatory effects of Vietmanese plant X methanol extract in LPS-induced BV-2 microglia cells

Jeong-In Park1, Joon-Soo Kim1, Yu-Ri Han2, Hyae-Shin Lee2, Byung-Wook Kim1, Hyun-Myung Ko2, and Dong-Kug Choi1,2,*1Department of Applied Life Science, BK21plus Glocal Education program of of Nutraceuticals Development, Konkuk University, Chungju 27478, Korea,



CXCR4-STAT3 Pathway is Essential for the Characteristic of Glioblastoma and Mesenchymal Property

Haeri Lee1, Byung-Hak Kim1,2, Eun Hee Yi1,2, Sunho Kwon1, Ae Jin Jeong1, Kum Hee Noh1, Song-Hee Lee1, Yong-Jin Kwon1, and Sang-Kyu Ye1,2,*1Department of Pharmacology, Seoul National University College

of Medicine,, 2Biomedical Science Project (BK21PLUS), Seoul National University College of Medicine

Cytoprotection of transplanted pancreatic islets using amphiphilic bilirubin nanoparticles for Type 1 diabetes therapy

Min Jun Kim1, Seung Ah Lee1, Dong Hoon Kang1, Sangyong Jon2, and Dong Yun Lee1,*1Department of Bioengineering, College of Engineering, and BK21 PLUS Future Biopharmaceutical Human Resources Training and Research Team, Hanyang University, Seoul

133-791, Republic of Korea, 2KAIST Institute for the BioCentury, Department of Biological Sciences, Korea Advanced Institute of Science and Technology, 291 Daehak-ro, Daejeon 305-701, Republic of Korea

Del-1 overexpression potentiates lung cancer cell proliferation and invasion

Seung-Hwan Lee1, Dong-Young Kim1, Feifeng Jing1, Hyesoon Kim1, Chae-Ok Yun2, Deok-Jong Han3, and Eung Young Choi1,*1Department of Biomedical Sciences, University of Ulsan College of Medicine, Seoul, Republic of Korea,

2Department of

Bioengineering, College of Engineering, Hanyang University, Seoul, Republic of Korea, 3Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea

Development of microfluidic platform for indirect co-culture of stem cells from human exfoliated deciduous teeth and various oral cells

Seon Min Ju, Kyung-Jung Kang, Jeongyun Kim*, and Young-Joo Jang*Department of Nanobiomedical Science & BK21 PLUS Global Research Center for Regenerative Medicine, Dankook University, 29 Anseo-Dong, Cheonan, 330-714, Korea

Development of orally absorbable lactoferrin-heparin bioconjugate to cure glioblastoma multiforme (GBM)

Hae Hyun Hwang, Woo Ri Bae, Si Jin Park, and Dong Yun Lee*Department of Bioengineering, College of Engineering, and BK21 PLUS Future Biopharmaceutical Human Resource Training and Research Team, Hanyang University, Seoul 133-791, Republic of Korea

Developmental endothelial locus-1 attenuates lung fibrosis via regulation of TGF-beta activation

Dong-Young Kim, Seung-Hwan Lee, Feifeng Jing, Yan Fu, and Eun Young Choi*Department of Biomedical Sciences, University of Ulsan College of Medicine, Seoul, Republic of Korea

Effect of Fermented Gastrodia elata Blume extract in LPS-stimulated neuroinflammation model

Joon-Soo Kim1, Yo-Sep Yun1, Duk-Yeon Cho1, Seon-Min Kim2, Seo-Young Shin2, Yu-Ri Han2, Byung-Wook Kim1, Hyun-Myung Ko2, and Dong-Kug Choi1,2,*1Department of Applied Life Science, BK21plus Glocal Education program of of Nutraceuticals Development, Konkuk University, Chungju 27478, Korea,



Effects of CI extracts and its bioactive compounds in in vivo and in vitro Experimental models

Yo-Sep Yun1,2, Duk-Yeon Cho1, Shin-Young Park1,2, Jeong-In Park1,2, Jun-Soo Kim1,2, Yu-Ri Han1, Hye-sin Lee1, Byung-Wook Kim2, Hyun Myung Ko2, and Dong-Kug Choi1,2,*1Department of Biotechnology, College of Biomedical and Health

science, Konkuk University, Chungju 380-701, Korea, 2Department of Applied Life Science, BK21plus Glocal Education program of of Nutraceuticals Development, Konkuk University, Chungju 27478, Korea

Effects of Sar1A Gene on Collagen Synthesis Induced by TGF-/Smad Signaling in Human Hypertrophic Scars

Il-Hwan Yu, and Jun-Sub Kim*Department of Biotechnology, Korea National University of Transportation, Jeungpyung 368-701, Korea

vPK Encoded by Kaposis Sarcoma-associated Herpesvirus Inhibit T-Cell Factor-Dependent Transcription via preventing interaction between -catenin and TCF4

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Poster Session List


Seho Cha, and Taegun Seo*Departments of Life Science, Dongguk University-Seoul, Seoul, Republic of Korea

EH22 attenuates glial activation against Lipopolysaccharide in BV-2 microglial cell and effect of EH22 on the behavioral deficits in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Mice

Shin-Young Park1, Jeong-In Park1, Joon-Soo Kim1, Duk-Yeon Cho2, Seo-Young Shin2, HyunMyung Ko1, In Su Kim1,2, and Dong-Kug Choi1,2,*1Department of Biotechnology, College of Bioedical and Health

science, Konkuk University, Chungju 380-701, Korea, 2Department of Applied Life Science, BK21plus Glocal Education program of of Nutraceuticals Development, Konkuk University, Chungju 27478, Korea*Correspoding author: [email protected]

Extracellular Matrix (ECM)-Immobilized Reporter for Sensing the Secretion and Activity of Matrix Metalloproteinases (MMPs)

Hawon Lee1,2, and Young-Pil Kim1,2,*1Department of Life Science, 2Research Institute for Natural Sciences, Hanyang University, Seoul 133-791, Republic of Korea

Functional role of phospholipase C on the therapeutic effects of WKYMVm against polymicrobial sepsis

Hyung Sik Kim1, Sung Kyun Lee1, Min Young Park1, Ji Cheol Kim1, and Yoe-Sik Bae1,2,*1Department of Biological Sciences, Sungkyunkwan University,

Suwon, Republic of Korea, 2Department of Health Sciences and Technology, SAIHST, Sungkyunkwan University, Seoul, Republic of Korea

Functional study of chloride channel protein in development and grain yield of rice

Tae Young Um, Geupil Jang, Sunhyun Chang, Sang Yool Lee, and Yang Do Choi*Department of Agricultural Biotechnology, Seoul National University, Seoul 151-921, Korea

Gastrodia elata Blume extract modulates antioxidant activity and UVA-irradiated skin aging in human dermal fibroblast cells

Eunju Song1, Haeyon Chung2, Eugene Shim2, Jung-ky Jeong3, Bok-kyung Han3, Hyuk-Joon Choi3, and Jinah Hwang1,*1Myongji University, 2Soongeui Womens College, 3BK Bio Co. Ltd.

Gene regulatory program directed by ASL9 in the Arabidopsis secondary growth

Jung-Hun Lee1, Jae-Young Yun2, Jin-Soo Kim2,*, and Ji-Young Lee1,*1School of Biological Sciences, Seoul National University, Seoul, Korea,

2Center for Genome Engineering, Institute for Basic

Science, Seoul, South Korea.

GHOST is Associated with Multidrug Resistance of Ovarian Cancer by Regulating MDR1 Expression

Yeong Min Chio1,2, Jung Suk Lee1,2, Ji Yea Kim1,2, Jun Woo Lee1,2, Sungkwan An1,2, and Seunghee Bae1,2,*1Department of Bioengineering, Konkuk University, Seoul 05029, Republic of Korea, 2Korea Institute for Skin and Clinical Sciences, Cheongju-si 28160, Republic of Korea

Ginsenoside F2 Treatment Attenuates Alcohol-induced Liver Disease of Mice by Inhibiting Hepatic Lipogenesis and Inflammation

Myung-Ho Kim, Ju Yeon Jung, and Won-Il Jeong*Laboratory of Liver Research, Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology, Daejeon, Republic of Korea

HPI Axis Effects on Stress Response in Zebrafish: Behavioral Responses

Junyoung Oh1, Hye Min Seo2, Wan Taek Kim2, and Seungheon Lee1,2,*1Department of Aquatic Biomedical Sciences, School of Marine

Biomedical Science, College of Ocean Science, Jeju National University, Jeju 690-756, Republic of Korea, 2Major of Aquatic Life Medicine, School of Marine Biomedical Science, College of Ocean Science, Jeju National University, Jeju 690-756, Republic of Korea

Identification of a Novel IQSEC3-interacting Protein

Dong Seok Park1, Gopal Pramanik2, Gayoung Choii3, Theofilos Papadopoulos4, Taesun Yoo5, Hyun Woo Lee6, Esther Yang6, Yeunkum Lee5, Eunjoon Kim5, Katsuhiko Tabuchi2, Hyun Kim6, Jaewon Ko3, and Ji Won Um1,*Department of Physiology and BK21 PLUS Project for Medical Science, Yonsei University College of Medicine, Seoul 120-751, Korea, 2Shinshu University School of Medicine, Matsumoto 390-8621, Japan, 3Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul 120-749, Korea, 4Department of Molecular Biology, University Medicine Gttingen, Gttingen, Germany, 5Center for Synaptic Brain Dysfunctions, Institute for Basic Science (IBS), Daejeon 305-701, Korea, 6Department of Anatomy and Neuroscience, Korea 21 Biomedical Science, College of Medicine, Korea University

Interaction of Human-pathogenic organism, Shigella with Arabidopsis thaliana

Sung Hee Jo1,2, Moo Seung Lee3, Dae Hee Lee4, and Jeong Mee Park1,2,*11Plant Systems Research Center, KRIBB, 125 Gwahak-ro, Yuseong-Gu, Daejeon, 305-806, Korea,

22Biosystems and

Bioengineering, University of Science and Technology, Gajeong-ro 217, Yuseong-Gu, Daejeon, 305-350, Korea, 33Department of Infection and Immunity Research Center, KRIBB,

125 Gwahak-ro, Yuseong-Gu, Daejeon, 305-806, Korea, 4Biochemicals and Synthetic Biology Research Center, KRIBB, 125 Gwahak-ro, Yuseong-Gu, Daejeon, 305-806, Korea

Investigation on antibacterial activity compounds via open column chromatography from Dendropanax morbifera Leveille extract

Kwonseong Kim, Seungbin Cha, Hackyoung Kim, Yeonji Lee, Seokyoung Lee, Wonbin Lee, Jinhwan Jang, and Youngjun Kim*Department of Applied Biochemistry, Konkuk University, Chung-Ju, 380-701, Republic of Korea

Investigation on the effect of black rice extract on protein phosophatases

Kkabi Son, Yeonji Lee, Hackyoung Kim, Seungbin Cha, and Youngjun Kim*Department of Applied Biochemistry, Konkuk University, Chung-Ju, 380-701, Republic of Korea

IQSEC3 functions as an Npas4 downstream target to promote inhibitory synapse formation in synaptic activity-dependent manner

Hyeyeon Kang1, Gayoung Choii2, Sookyung Hong3, Jongcheol Jeon3, Jaehoon Kim3, Jaewon Ko2, and JiWon Um1,*1Department of Physiology and BK21 PLUS Project for Medical Science, Yonsei University College of Medicine, Seoul 120-751, Korea, 2Department of Biochemistry, College of life Science and Biotechnology, Yonsei University, Seoul 120-749, Korea, 3Department of Biological Sciences, Korea Advanced Institute of

Science and Technology(KAIST), Daejeon 305-701, Korea

Lysimachia foenum graecum Herba extract, a novel biopesticide, inhibits ABC transporter genes and mycelial growth of Magnaporthe oryzae

Myoung Ho Joo, Yu Mi Yeo, Su Jin Kim, Tae Chul Moon, Jung Su Park, Sol Ji Lee, Young A Kim, Hyeon Hwa Kim, Sung Young Cho, and Young Jin Lee*Faculty of Department of Oriental Pharmaceutical Development, Laboratory of Plant Molecular Pathology, The Nambu University, Gwangju 506-706, Korea

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Metabolic Regulation Of Histone Acylations In Myotube

Chanhee Jo, and Eun-jung Cho*School of Pharmacy Sungkyunkwan University, 300 Cheoncheon-dong, Jangan- gu, Suwon, Gyeonggi-do 440-746, South Korea

Methyl 5-[2-(dimethylamino)ethoxy]-7, 12-dioxo-7, 12-dihydrodinaphtho[1,2-b:2',3'-d]furan-6- carboxylate (DFC2) exerted anti-mycobacterial activity by inhibiting mycolic acid biosynthesis

Sukyung Kim, Woong sik Jang, Hoonhee Seo, Jyoti Md.anirban, Juhye Han, and Ho-yeon Song*Department of microbiology, School of medicine, Soonchunhyang University

Mini pigs for Gastritis animal model : Gastric ulcer

Won kyu Lee1, Tae hyun Ko2,*, Hwan hee Park3, Thi thuy linh Tran4, Yulia Pyao5, and Memon Azra61Inha university,

2Inha university,

3Inha university,

4Inha uni-

versity, 5Inha university, 6Inha university

Mitotic DNA damage checkpoint: from bypass of mitosis to multiploidy formation

Sun Yi Hyun, and Young-Joo Jang*Department of Nanobiomedical Science & BK21 PLUS Global Research Center for Regenerative Medicine, Dankook University, 29 Anseo-Dong, Cheonan, 330-714, Korea

Neuropeptide CNMa in DN1p Clock Neurons is Dispensable for Circadian Rhythmicity of Locomotor Behavior

Ivana Daubnerov, Sung-Hwan Jung, and Young-Joon Kim*School of Life Sciences, Gwangju Institute of Science and Technology, Gwangju 500-712, Republic of Korea

Oxidation inactivation of protein tyrosine phosphatase MTMR1

Hackyoung Kim, Hanna Go, Seokyoung Lee, and Youngjun Kim*Department of Applied Biochemistry, Konkuk University, Chung-Ju, 380-701, Republic of Korea

Peroxiredoxin 5 inhibits amyloid-beta oligomer-induced neuronal apoptosis by inhibiting ERK-Drp1-mediated mitochondrial fragmentation

Bokyung Kim, and Dong-Seok Lee*School of Life Sciences, BK21 Plus KNU Creative BioResearch Group, Kyungpook National University, Daegu 702-701, Republic of Korea

Phospholipase C 1 regulates foreign body giant cell formation

Ye Seon Kim1, Chang Youp Ok1, Min Young Park1, Ji Cheol Kim1, and Yoe-Sik Bae1,2,*1Department of Biological Sciences, Sungkyunkwan University, Suwon, Republic of Korea, 2Department of Health Sciences and Technology, SAIHST, Sungkyunkwan University, Seoul, Republic of Korea

Preferential induction of the T cell auxiliary signaling molecule B7-H3 on synovial monocytes in rheumatoid arthritis

Bo Ruem Yoon1, Yeon-Ho Chung1,2, Su-Jin Yoo3, Jinhyun Kim3, In Seol Yoo3, Seong Wook Kang3, and Won-Woo Lee1,2,4,*1From theDepartment of Microbiology and Immunology, Seoul National University College of Medicine, 2BK21Plus Biomedical Science Project, Seoul National University College of Medicine, 3Department of Internal Medicine, Chungnam National University School of Medicine, 4Department of Biomedical Sciences, Seoul National University College of Medicine

Protective Effect on UVB Irradiation of Microalgae Tetraselmis sp. as a Novel Anti-skin Aging Resource

Seunghee Bae1,2, Ji-Eun Park1,2, Hyunmin Kim1,2, Ayeong Lee1,2, Sungkwan An1,2, and In-Sook An2,*1Korea Institute for Skin and Clinical Sciences, Cheongju-si 28160, Republic of Korea,

2Department of Bioengineering,

Konkuk University, Seoul 05029, Republic of Korea

RhoGDI Degradation by Enterokinase Negatively Regulates Its Function in Glioblastoma

Il-Hwan Yu, and Jun-Sub Kim*Department of Biotechnology, Korea National University of Transportation, Jeungpyung 368-701, Korea

Sequential Analysis of MAP Kinase and GSK-3 Activities using Microfluidic Isoelectric Focusing

Hoseok Choi1, Bu Taek Lim1, Nakchul Choi3, Simon Song2,3, Tae-Wuk Kim1, and Young-Pil Kim1,2,*1Department of Life Science, Hanyang University, 2Institute of Nano Science and Technology, Hanyang University, 33Department of Mechanical Convergence Engineering, Hanyang Universityu

Serum amyloid A stimulates dendritic cell maturation via Toll-like receptor 4

Ji Cheol Kim1, Young Su Jung1, Hyung Sik Kim1, Ye Seon Kim1, and Yoe-Sik Bae1,2,*1Department of Biological Sciences, Sungkyunkwan University, Suwon, Republic of Korea,

2Department of Health Sciences and

Technology, SAIHST, Sungkyunkwan University, Seoul, Republic of Korea.

Sleep Patterns in Thalamic-restricted PLC4 Knock-down Mice

Joohyeon Hong1, Jungryun Lee2, Go Eun Ha1, Hankyul Kwak1, Gyeong-Eon Chang1, Rina Song1, Hyelin Ji1, Pann-Ghill Suh3, Hee-Sup Shin2, and Eunji Cheong1,*1Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul, Republic of Korea, 2Center for Cognition and Sociality, Institute for Basic Science, Daejeon, Republic of Korea, 3Center for Cell to Cell Communication in Cancers (C5), School of Life Sciences, Ulsan National Institute of Science and Technology, Ulsan, Republic of Korea

Sulfiredoxin inhibitor induces preferential death of cancer cells through reactive oxygen species-mediated mitochondrial damage

Gong-Rak Lee1, Hojin Kim1, Jiwon Kim1, Jin Young Baek4, You-jin Jo1, Seong-Eun Hong1, Sung Hoon Kim1, Jiae Lee1, Hye In Lee1, Song-Kyu Park2, Hwan Mook Kim3, Hwa Jeong Lee4, Tong-Shin Chang4, Sue Goo Rhee5, and Woojin Jeong1,*Department of Life Science and the Research Center for Cellular Homeostasis, Ewha Womans University, Seoul 120-750, South Korea, 2College of Pharmacy, Korea University, Sejong 339-700, South Korea, 3College of Pharmacy, Gachon University of Medicine and Science, Incheon 406-799, South Korea,

4College of

Pharmacy, Ewha Womans University, Seoul 120-750, South Korea, 5Yonsei Biomedical Research Institute, Yonsei University College of Medicine, Seoul 120-752, South Korea

The E3 Ubiquitin Ligase Exorcist Negatively Regulates GHOST via Ubiquitin-proteasomal Pathway

Yeong Min Chio1,2, Ji Yea Kim1,2, Jun Woo Lee1,2, Seunghee Bae1,2, and Sungkwan An1,2,*1Department of Bioengineering, Konkuk University, Seoul 05029,

Republic of Korea, 2Korea Institute for Skin and Clinical Sciences, Cheongju-si 28160, Republic of Korea

The lacking of NOX2 attenuates ethanol-induced hepatic steatosis via down-regulating CB1R signaling pathway in mice

Jong-Min Jeong, So Yeon Kim, and Won-Il Jeong*Lab of Liver Research, Graduate School of Medical Science and Engineering, KAIST, Daejeon 305-338, Republic of Korea

The regulation in the ubiquitination machinery for histone H2B ubiquitination

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Poster Session List


Jueun Kim, Yu-Kyoung An, and Jung-Shin Lee*Molecular Biochemistry Lab, Department of Molecular Bioscience, College of Biomedical Science, KangwonNational University, 1 Kangwondaehak-gil, Chuncheon-si, Gangwon-do, 200-701 Republic of Korea

The Resistance to Gossypol in ATG5 Knockout Cells Is Associated with Increased Cytoprotective Autophagy, Independent of ATG5

Sung-Hee Hwnag, Na-Yeon Kim, and Michael Lee*Division of Life Sciences, College of Life Sciences and Bioengineering, Incheon National University, Incheon 406-772, Republic of Korea

The Role of Oasl1 in the Pathogenesis of Atherosclerosis

Haejung Kim, Sejin Jeon, and Gootaeg Oh*Department of life sciences and GT5 program, Ewha Womans University, Seoul

vIRF3 Encoded by Kaposis Sarcoma-associated Herpesvirus Inhibit T-Cell Factor-Dependent Transcription via CREB-Binding Protein-Interaction Motif.

Seho Cha, and Taegun Seo*Departments of Life Science, Dongguk University-Seoul, Seoul, Republic of Korea.

UVB Induced Cell Dysfunction is Protected by an Extract of microalgae Ettlia sp. in Normal Human Dermal Fibroblasts

Jeong-Ju Lee1,2, Hyein Kim1,2, Eunji Lee1,2, In-Sook An2, Sungkwan An1,2, and Seunghee Bae1,2,*1Department of Bioengineering, Konkuk University, Seoul 05029,

Republic of Korea, 2Korea Institute for Skin and Clinical Sciences, Cheongju-si 28160, Republic of Korea

Ascochlorin Inhibits c-Myc Expression by Regulation of ERK Phosphorylation

Yun-Jeong Jeong*, Jae-Moon Shin, Mun-Hyeon Kim, and Ji-Young SeokResearch Institute of Biomedical Engineering and Department of Cell Biology, Catholic University of Daegu School of Medicine, Daegu 705-718, Korea

ChRO1, a novel long non coding RNA involved in myogenesis and chromatin remodeling

Jinyoung Park, and Eun-Jung Cho*School of Pharmacy Sungkyunkwan University, 300 Cheoncheon- dong, Jangan-gu, Suwon, Gyeonggi-do 440-746, South Korea

Cleavage of Aryl Hydrocarbon Receptor Nuclear Translocator (Arnt) in Adipocytes

Seongyeol Lee, and Hyunsung Park*Department of Life Science, University of Seoul, Seoul, Korea 130-743

Expansion of CD8+ T cells lacking the IL-6 receptor

chain in patients with coronary artery diseases (CAD)

Yuri Hwang1, Hee Tae Yu2, Jiyeon Jang1, Dong-Hyun Kim3,4, Hee Young Kim1,5, Insoo Kang6, Hyeon Chang Kim7, Sungha Park2,*, and Won-Woo Lee1,3,4,8,*1Department of Microbiology and Immunology, Seoul National

University College of Medicine, Seoul 110-799, South Korea, 2Division of Cardiology, Severance Cardiovascular Hospital and Cardiovascular Research Institute, Yonsei University College of Medicine, Seoul, Korea, 3Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul 110-799, South Korea,

4BK21Plus Biomedical Science Project, seoul

National University College of Medicine, Seoul 110-799, South Korea, 5Cancer Research Institute, Seoul National University College of Medicine, Seoul 110-799, South Korea,

6Department of

Internal Medicine Yale University School of Medicine, New Haven, Connecticut., 7Cardiovascular and Metabolic Diseases Etiology Research Center and Department of Preventive Medicine, Yonsei University College of Medicine, Seoul, Korea, 8Ischemic/Hypoxic Disease Institute, and Institute of Infectious

Diseases, Seoul National University College of Medicine; Seoul National University Hospital Biomedical Research Institute, Seoul 110-799, Korea

Expression and analysis of 13

C615

N4-arginine labeled human growth hormone in Escherichia coli

Jin-Hee Lee1,2, Jimyeong Song1,2, and Jun-Hyuk Choi1,2,*1Center for Bioanalysis, Department of Metrology for Quality of Life, Korea Research Institute of Standards and Science, Daejeon, Korea, 2Department of Bio-Analytical Science, University of Science & Technology, Daejeon, Korea

L-Asparaginase delivered by Salmonella typhimurium suppresses solid tumors

Kwang soo Kim*, Jae Ho Jeong, Dae Jin Lim, Kun-Hee Kim, Kyeong il Park, Shinnam Li, Hyun-Ju Kim, and Hyon E. ChoyDepartment of Microbiology,Chonnam National University Medical School, Hak dong, Dong-gu, Korea*Corresponding author: [email protected]

Multisynthetase complex auxiliary component inhibits cryptic proliferation and intestinal adenoma formation

Min-Kyu Yum, Jong-Seol Kang, Young-Woo Woo, Eun-Byul Lee, and Young-Yun Kong*Department of Biological Sciences, Seoul National University, Seoul, 151-747, South Korea

NADPH oxidase deficiency ameliorates high fat diet-induced steatosis and insulin resistance of liver in mice

So Yeon Kim, Jong-Min Jeong, and Won-Il Jeong*Lab of Liver Research, Graduate School of Medical Science and Engineering (GSMSE), 291 Daehak-ro, Yuseong-gu, Daejeon 34141, Republic of Korea, KAIST

Pathogenic Upregulation of Glial Lipocalin-2in Parkinsonian Dopaminergic System

Byung-Wook Kim1,2, Dong-Kug Choi1, Sang-Ryong Kim3, and Kyoungho Suk2,*1Department of Applied Life Science, BK21plus Glocal Education program of of Nutraceuticals Development, Konkuk University, Chungju 27478, Korea,

2Department of Pharmacology, Brain

Science & Engineering Institute, Kyungpook National University School of Medicine, Daegu, 41944, Korea, 3School of Life Sciences, BK21 plus KNU Creative BioResearch Group, Brain Science and Engineering Institute, Kyungpook National University, Daegu, 41566, Korea

RAC signaling pathway regulates interaction of YAP between TEAD and RUNX3 by inhibiting LATS

Min-Kyu Kim, Ju-Won Jang, and Suk-Chul Bae*Department of Biochemistry, School of Medicine, and Institute for Tumor Research, Chungbuk National University

Raf, Hypoxia and the stability of Tafazzin (TAZ)

Sungwook Yoo, Soojeong Chang, and Hyunsung Park*Department of Life Science, University of Seoul, Siripdae-gil 13, Dongdaemun-gu, Seoul 130-743, Korea

Characterization of Glis2 Binding Partner, OTX1, and Its Function in Glis2 Transcriptional Activity

Miso Jeon1,2, Hong Soon Kang3, Naimur Rahman1,2, Anton M. Jetten3, and Yong-Sik Kim1,2,*1Dept. of Microbiology, College of Medicine, Soonchunhyang University, Korea, 2Institute of Tissue Engineering, College of Medicine, Soonchunhyang University, Korea,

3Immunity,

Inflammation, and Disease Laboratory, NIEHS/NIH, USA

Structural study of uropathogenic E. coli specific protein chuY

Hun Kim1, Jongkeun Choi2, Doyoun Kim1,3, and Kyeong Kyu Kim1,*1Department of Molecular Cell Biology, Sungkyunkwan University School of Medicine, Suwon 440-746, Korea,

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2Department of Cosmetic Science, Chungwoon University, Hongseong Chungnam 350-701, Korea,

3Center for Synaptic

Brain Dysfunctions, Institute for Basic Science, Daejeon 305-701, Korea

A Novel compound from Antarctic lichen restores cognition via suppression of inflammasome and BACE1 expression in Alzheimers disease mice

Bo Youn Choi, and Dong-Gyu Jo*School of Pharmacy, Sungkyunkwan University, Suwon 440-746, Republic of Korea

A Study on Optimizing Mouse Embryo Culture Media and Its Application

Min Young Kim, Sung Han Lee, Mi Hwa Kwon, Seong Wook Cho, Hyun Sup Lim, and Yun Seok Heo*Dept of Bio Medical Engineering, School of Medicine, Keimyoung Univ.

A Systems Biology Approach for Understanding Mechanisms of New TB Drug: DPG5

Hoonhee Seo, Sukyung Kim, Tamanna Zerin, Md. Aniban Jyoti, Woongsik Jang, and Hoyeon Song*Department of Microbiology, School of Medicine Soonchunhyang University Gradute School, Korea

Abscisic Acid Transporters Cooperate to Control Seed Germination

Areum Kim1, Joohyun Kang1,3, Sojeong Yim1, Hyunju Choi1, Keun Pyo Lee2, Luis Lopez-molina2, Enrico Martinoia3, and Youngsook Lee1,4,*11POSTECH-UZH Global Research Laboratory, Division of Molecular Life Sciences, Pohang University of Science and Technology, Pohang, 790-784, Korea, 2Dpartment de Biologie Vgtale, Universit de Genve, 1211 Geneva 4, Switzerland, 3Institut fr Pflanzenbiologie, Universitt Zrich, Zolliker strasse

107, 8008 Zrich, Switzerland, 4Division of Integrative Biology and Biotechnology, POSTECH, Pohang, 790-784, Korea

Afterhyperpolarization Currents in Thalamocortical Neurons Are Mediated by Calcium-Activated Chloride Channels

Go Eun Ha1, Jaekwang Lee2, Hankyul Kwak1, Kiyeong Song1, Jae Kwon2, Soonyoung Jung2, Joohyeon Hong1, Gyeong-Eon Chang1, C. Justin Lee2, and Eunji Cheong1,*1Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul, Republic of Korea, 2Center for Neural Science, Korea Institute of Science & Technology, Seoul, 136-791, Republic of Korea

Anti-candida Action Mechanism of Halocidin-Histatin 5 Hybrid Peptides

Juhye Han, Anirban Jyoti, Tamanna Zerin, Sukyung Kim, Hoonhee Seo, Ho-yeon Song*, and Woongsik Jang*Department of Microbiology and Immunology, School of Medicine, Soonchunhyang University

Characterization of Mouse-adapted influenza B virus

Eun-Ha Kim, Su-Jin Park, Hyeok-Il Kwon, Se Mi Kim, Young-il Kim, Young Jae Si, In Won Lee, and Young-Ki Choi*Microbiology Department, College of Medicine and Medical Research Institute, Chungbuk National University, 12 Gaeshin-Dong Heungduk-Ku, Cheongju 361-763, Republic of Korea

Conserved role of uridylation in maternal mRNA decay during embryo development

Jinah Yeo1,2, Hyeshik Chang1,2, Jung-gyun Kin3, Jaechul Lim1,2, Hee-Yeon Jeon2, Hyun Ho Kim3, Jiyeon Ok4, Hosung Jung4, Hyunsook Lee2, Kyuwon Kim3, and V. Narry Kim1,2,*1Center for RNA Research, Institute for Basic Science,

2School of

Biological Sciences, Seoul National University, Seoul, Korea, 3College of Pharmacy, Seoul National University, Seoul, Korea, 4Department of Anatomy, Yonsei University College of Medicine,

Seoul, Korea

Crystal Structure of FRIGIDA Flowering-Time Regulator Provides Structural Basis of Non-functional Allele

Kyung-gi Hyun1, Jee Eun Oh2, Jihye Park1, Yoo-Sun Noh2, and Ji-Joon Song1,*1Department of Biological Sciences, KAIST, Daejeon, 305-701,

Korea, 2School of Biological Sciences, Seoul National University, Seoul, 151-747, Korea

Description of Lysobacter sp. nov., Isolation from Soil

Dongwook Lee, and Taegun Seo*Dongguk University Biomedi Campus 32, Dongguk-ro, Ilsandong-gu, Goyang-si, Gyeonggi-do, Republic of Korea

Different effects of hormones on striated muscles

Sung-Hwan Bae, Ji-Hoon Kim, Inkuk Park, Ji-Yun Seo, Gi-Chan Han, Sang-Hyeon Hann, and Young-Yun Kong*Department of Biological Sciences, College of Natural Sciences, Seoul National University, Seoul, Korea

Different patterns of diverse Notch receptor signaling pathway in muscle development

Inkuk Park, Ji-Hoon Kim, Ji-Yun Seo, Young-Woo Jo, Sang-Hyeon Hann, and Young-Yun Kong*Department of Biological Science, Seoul National University, Seoul, 151-747, Korea

Differentially methylated histone code for regulation of gene expression under hypoxia

Seongyeol Lee1, Jieon Lee2, Sehyun Chae3, Yunwon Moon1, Bongju Park1, Daehee Hwang2,3,*, and Hyunsung Park1,*1Department of Life Science, University of Seoul, Seoul, 130-743, Republic of Korea,

2Department of Chemical Engineering,

POSTECH, Pohang, 780-784, Republic of Korea, 3Department of New Biology and Center for Plant Aging Research, Institute of Basic Science, DGIST, Daegu, 711-873, Republic of Korea

Disruption of Two ABC Transporters, ABC-a and ABC-b, Affects Arabinogalactan Protein Deposition and Pollen Mitosis I During Male Gamete Formation in Arabidopsis

Sojeong Yim1, Deepa Khare1, Joohyun Kang1, Jae-Ung Hwang1, Enrico Martinoia2, Byungho Kang3, and Youngsook Lee1,*1POSTECH-UZH Global Research Laboratory, Division of

Integrative Biology and Biotechnology, POSTECH, Pohang, 790-784, Korea, 2Institut fur Pflanzenbiologie, Universitat Zurich, Zollikerstrasse 107, 8008 Zurich, Switzerland,

3School of Life

Sciences, 409E, Science Centre The Chinese University of Hong Kong, China

Drug repositioning of XHC for Alzheimers disease: BACE1 promoter repressing activity of XHC

Gun Young Jung, Bo Youn Choi, Ga Hee Bahn, Hee Jin Park, and Dong Gyu Jo*School of Pharmacy, Sungkyunkwan University, Suwon 440-746, Republic of Korea

Effect of the soil composition on expression of prostatic acid phosphatase (PAP)-Fc fusion protein as a vaccine candidate for prostate cancer in transgenic plant and its plant growth

Kisung Ko*, and Yang-joo KangTherapeutic Protein Engineering Lab, Department of Medicine, College of Medicine, Chung-AngUniversity, Seoul, South Korea

Epigenetic Reprogramming of Pluripotency Genes Identified by Global DNA Methylation Analysis in the Human Genome

Na Young Choi, Jin Seok Bang, Yo Seph Park, Hye Jeong Lee, and Kinarm Ko*Department of Stem Cell Biology, School of Medicine, Konkuk University, Seoul 05029, Korea

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Poster Session List


Exploring Conformational Space of Linear Polyubiquitin Chains by Crystallographic and Small-Angle X-ray Scattering (SAXS) studies

Donghyuk Shin, Trung Thanh Thach, Seungsu Han, and Sangho Lee*Department of Biological Sciences, Sungkyunkwan University

Feeder free induction of pluripotency in unipotent spermatogonial stem cells

Seung-Won Lee, Yo Seph Park, Na Young Choi, Min Seong Lee, and Kinarm Ko*Department of Stem Cell Biology, School of Medicine, Konkuk University, Seoul 143-701, Korea

Functional Analysis of an ABC Transporter Involved in Early Seedling Development of Arabidopsis

Eun-Jung Lee1, Fred Beisson2, Byung-Ho Kang3, and Youngsook Lee1,*1Division of Integrative Bioscience and Biotechnology, POSTECH, Korea, 2CNRS/CEA/Aix-Marseille University, F-13108 Cadarache, France,

3University of Florida, Gainesville,

FL 32611, USA

HER2-targeting ADC containing cleavable linker for targeted therapy of HER2-positive gastric cancer

Seol Hwa Shin1,2, Jinhyang Choi1,2, Seok Soon Park1,2, Jae Hee Lee1,2, Kyoung Jin Lee1,2, Eun Jin Ju1,2, Jin Park1,2, Eun Jeong Ko1,2, Intae Park1,2, Si Yeol Song1,2,3,*, Seong-Yun Jeong1,2,*, and Eun Kyung Choi1,2,3,*1Institute for Innovative Cancer Research, ASAN Medical Center, 2Center for Advancing Cancer Therapeutics, ASAN Medical Center,

3Department of Radiation Oncology, University of Ulsan

College of Medicine

HLH protein can regulate mammary gland development in virgin mice

Jinwoo Seong, Jee-Ah Kim, Nam-Shik Kim, Ji-Yun Seo, Miin-kyu Yum, and Young-Yun Kong*Department of Biological Sciences, College of Natural Sciences, Seoul National University, Seoul, Republic of Korea

Hypoxia Attenuates Oncogene-Induced Senescence

Soojeong Chang, and Hyunsung Park*Department of Life Science, University of Seoul, Siripdae-gil 13, Dongdaemun-gu, Seoul 130-743, Korea

Hypoxia Ex-vivo Expansion Improves Proliferation and Effector Activities of Human NK cells

Yunwon Moon1, Seon Ah Lim2, Kyung-Mi Lee2, and Hyunsung Park1,*1Department of Life Science, University of Seoul,

2Department of

Biochemistry and Molecular Biology, Korea University College of Medicine

Hypoxic reprogramming on histone methylation of H19 imprinting gene

Ingyum Kim, Seongyeol Lee, and Hyunsung Park*Department of Life Science, University of Seoul, Seoul, 130-743, Republic of Korea

Identification of neural stem cell specific microRNA by genome-wide screening as critical player in stemness

Yukyeong Lee, Hye Jeong Lee, Seung-Won Lee, and Kinarm Ko*Department of Stem Cell Biology, Konkuk University School of Medicine, Seoul 05029, Korea

Identification of Phytophthora infestans core effectors that induce cell death on nonhost pepper

Soohyun Oh, Hyun-Ah Lee, Myung-Shin Kim, Youngsil Lee, Jieun Park, Eunhye Choi, and Doil Choi*Department of Plant Science and Plant Genomics and Breeding

Institute, College of Agriculture and Life Sciences, Seoul National University, Seoul 151-921, Republic of Korea

Identification of protein(s) regulating the function of AtABCG14, a transporter essential for the root to shoot delivery of cytokinin in Arabidopsis thaliana

Donghwi Ko1, Seungjun Lee1, Do-Young Kim2, Won-Yong Song1, and Youngsook Lee1,*1Division of Integrative Biology and Biotechnology, POSTECH,

Pohang, 790-784, Korea, 2Pohang Center for Evaluation of Biomaterials, Pohang Technopark, Pohang, 790-834, Korea

Identification of Target Proteins Interacting with Effectors of Phytophthora infestans in Non-host Pepper

EunBi Choi, Joo Hyun Lee, So Eui Lee, Saet-byul Kim, Eunyoung Seo, Seungill Kim, Gang-to Lee, and Doil Choi*Department of Plant Science and Plant Genomics Breeding Institute, College of Agriculture and Life Sciences, Seoul National University, Seoul

Inhibition of Mitochondrial Fission Ameliorates the Pathogenesis of Alzheimer's Disease

Hee Jin Park, Hark Kyun Kim, Youn Suk Cho, Bo Youn Choi, and Dong Gyu Jo*School of Pharmacy, Sungkyunkwan University, Suwon 440-746, Republic of Korea

Isolation and Identification of Marmoricola species from Soil

Jun Hyeong Jang, and Taegun Seo*Dongguk University Biomedi Campus 32, Dongguk-ro, Ilsandong-gu, Goyang-si, Gyeonggi-do, Republic of Korea

Large quaternary structure formation of antigen- antibody complex for colorectal cancer protective immune response via cross fertilization of both plants expressing GA733-FcK and mAb CO17-1AK

Kisung Ko1,*, Deuk-Su Kim1, Kinarm Ko2, and Soon Chul Myeung31Department of Medicine, College of Medicine, Chung-Ang

University, Seoul, Korea, 2Department of Stem Cell Biology, School of Medicine, Konkuk University, Seoul, Korea, 3Department of Urology, Chung-Ang University, College of

Medicine, Korea

Measurement of nucleotide excision repair kinetics in human cells

Jimyeong Song1,2, So-Young Kim1, Jin-Hee Lee1,2, and Jun-Hyuk Choi1,2,*1Center for Bioanalysis, Department of Metrology for Quality of Life, Korea Research Institute of Standards and Science, Daejeon, Korea,

2Department of Bio-Analytical Science, University of

Science & Technology, Daejeon, Korea

Methyl Gallate Inhibits 3T3-L1 Pre-adipocyte Differentiation through G1 Cell Cycle Arrest via pRb/E2F-1 Pathway

Naimur Rahman1,2, Miso Jeon1,2, and Yong-Sik Kim1,2,*1Dept. of Microbiology, College of Medicine, Soonchunhyang University, Korea, 2Institute of Tissue Engineering, College of Medicine, Soonchunhyang University, Korea

Mice lacking myofiber-specific Notch-regulating E3 ubiquitin ligase develop premature sarcopenia

Ji-Yun Seo, Sung-Hwan Bae, Jol-Seol Kang, Young-Woo Jo, and Young-Yun Kong*Department of Biological Science, Seoul National University, Seoul 151-747, Korea

Optimization of Ammonium Sulfate Concentration for Purification of Colorectal Cancer Vaccine Candidate Recombinant Protein GA733-FcK from Plants

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Kisung Ko*, Se-Ra Park, Chae-Yeon Lim, and Deuk-Su KimTherapeutic Protein Engineering Lab, Department of Medicine, College of Medicine, Chung-AngUniversity, Seoul, South Korea

Orally Absorbable Rebamipide Prodrug(SA001) for Prevention and Therapy of Dry Eye Syndrome

Jungrock Lee1, Beom Hyeon Jang1, Hyun Tae Kim1, Chan Heo1, Min-Hyo Ki1, Hee Jong Shin1,*, Sung Woo Lee2, and Eui-Hwan Cho21Samjin Research Institute, 6th Floor, Institute Pasteur Korea,

Seongnam, 463-400, Republic of Korea, 2Samjin Pharm Co. LTD., Seoul 121-739, Korea

Oxidative lipid modification of gamma-secretase in Alzheimers disease

Gahee Bahn1, and Dong Gyu Jo2,*1Sungkyunkwan University, 2Sungkyunkwan University

Pro-apoptotic Function of Pin1-Mediated Notch1 Activation in Ischemic Neuronal Death

Yoonsuk Cho, and Dong Gyu Jo*School of Pharmacy, Sungkyunkwan University, Suwon, Korea

Role of Adiponectin in the pathogenesis of Alzheimers disease

HarkKyun Kim, and Dong Gyu Jo*School of Pharmacy, Sungkyunkwan University, Suwon 440-746, Republic of Korea

Strategy for characterizing the putative ABC transporters functional in lipid metabolism in Chlamydomonas reinhardtii

Hanul Kim1, Sunghoon Jang1, Yasuyo Yamaoka1, Daewoong Hong1, and Youngsook Lee2,*1Division of Molecular Life Sciences, Pohang University of

Science and Technology, Pohang, Korea, 2POSTECH-UZH Global Research Laboratory, Division of Integrative Biology and Biotechnology, Pohang University of Science and Technology, Pohang, Korea

Strategy for Identification of Key Regulators of Lipid Accumulation in Chlamydomonas reinhardtii

Jihyun Lee1,*, Won-Yong Song2, Do-young Kim3, and Youngsook Lee4,*1Department of Integrative Bioscience & Biotechnology, POSTECH, 2Department of Life Science, POSTECH, 3Pohang Technopark,

4Department of Integrative Bioscience &

Biotechnology, Department of Life Science, POSTECH

Susceptibility of Dichloroacetate induced cell death in MCF-7 and MDA-MB-231 breast canceer cells

Je Won Yang, Yourim Shin, Youngmin Yoon, Juntak Noh, and Kwang Il Kang*Lab of Molecular Cell Biology, Korea Science Academy of KAIST, Busan, Korea

The drug TG reducing BACE1 expression level and preventing cognitive impairment in AD mice

Seung Hyun Baek, and Dong Gyu Jo*Department of Pharmacy, Sungkyunkwan University, 300 Chunchun-Dong, Jangan-Gu, Suwon, Gyeonggi-Do 440-746, Korea

The expression of ubiquitin-protein ligase is induced by sex hormones in muscle fibers

Young-Yun Kong*, Gi-Chan Han, Ji-Hoon Kim, Sanghyun Hann, Inkuk Park, and Youngwoo JoDepartment of Biological Sciences, College of Natural Sciences, Seoul National University, Seoul, Korea

The Histone H3K4 Methyltransferase Set1 is a Negative Regulator of Hyphal Formation in Candida albicans

Jueun Kim, and Jung-Shin Lee*Molecular Biochemistry Lab, Department of Molecular Bioscience, College of Biomedical Science, KangwonNational

University, 1 Kangwondaehak-gil, Chuncheon-si, Gangwon-do, 200-701 Republic of Korea

The interaction between Notch-1 and HIF-1 promotes ischemic neuronal death

Jihoon Han, and Dong Gyu Jo*School of Pharmacy, Sungkyunkwan University, Suwon 440-746, Republic of Korea

The Protective Effects of Extract from Marin Natural product Against Oxidative Induced Cellular

Han-Na Kim1, So-Yeon Lee1, Jeong-Min Lee1, Dong-Cheol Sin2, Kwan-Soon Park3, Jae-Chan Yang1,*, and Bo-Ae Kim1,*1Mokwon University, College of Sciences & Technology, Division of Biomedicinal & Cosmetics, Doanbuk-ro 88, Seo-gu, Daejeon 302-729, Korea,

2Nstech R&D Center, 270 Beon-Gil 28,

Namdongseo-Ro, Namdong-Gu, Incheon, , Korea, 3Marine & Eco Technology, 410 Ewha Officetel 50, Doryeong-ro, Jeju-si, Jeju-do 690-802, , Korea

Transcription-regulatory activity of bromodomain protein TRIM24 in Breast cancer

Suji Hong, Chan-Hee Jo, Jinyoung Park, Byung-Ho Kim, Il-Rang Song, Kwan-Young Jeong, and Eun-Jung Cho*Sungkyunkwan University

Effects of Smad decoy ODN on Atherosclerotic ApoE-/- Mice

Hyun-Jin An1, Jung-Yeon Kim1, Woon-Hae Kim1, Kwan-Kyu Park1, and Sung Won Youn2,*1Department of Pathology, College of Medicine, Catholic

University of Daegu, 2Department of Radiology, College of Medicine, Catholic University of Daegu

pamin suppresses activated hepatic stellate cells and biliary fibrosis

Jung-Yeon Kim, Kyung-Hyun Kim, Hyun-Jin An, Woon-Hae Kim, and Kwan-Kyu Park*Department of Pathology, College of Medicine, Catholic University of Daegu, Daegu, Korea

LRRTM3 Regulates Excitatory Synapse Development through Alternative Splicing and Neurexin Binding

Ji Won Um1,2, Tae-Yong Choi3, Gayoung Choii1, Sangmin Jeon1, Hyeyeon Kang2, Dong Seok Park2, Daun Jeong6, Hyun Kim7, Seung-Hee Lee6, Yong-Chul Bae4, Se-Young Choi3, Matti Airaksinen5, and And Jaewon Ko1,*1Department of Biochemistry, College of Life Science and

Biotechnology, Yonsei University, Seoul 120-749, Korea, 2Department of Physiology and BK21 PLUS Project to Medical Sciences, Yonsei University College of Medicine, Seoul 120-751, Korea, 3Department of Physiology, Dental Research Institute, Seoul National Univers

KSMCB Winter Conference 2016 Time Table

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Transcript of KSMCB Winter Conference 2016 Time Table