45ÝKU

K. A. D. Haberler

KLÝNÝK ARAÞTIRMALARDÜNYASINDAN HABERLER

Toplam klinik çalýþma sayýsý: 938Toplam sponsor sayýsý: 203

Sponsorlarýn %1'i klinik çalýþmalarýn %20'sini yürütüyor.Sponsorlarýn %6'sý klinik çalýþmalarýn yarýsýný yürütüyor.Sponsorlarýn yarýsý klinik çalýþmalarýn %90'ýný yürütüyor.

Klinik çalýþmalarýn

Sýra Sponsor Klinik çalýþma toplam sayýya oraný Kümülatif oran

no sayýsý (%) (%)

1 Glaxo Wellcome 120 12.8 12.82 Bristol-Myers Squibb 69 7.4 20.13 Hoffman-LaRoche 62 6.6 26.84 Pfizer 37 3.9 30.75 Merck 34 3.6 34.36 Gilead Sciences 29 3.1 37.47 Genentech 21 2.2 39.78 Pharmacia 20 2.1 41.89 Upjohn 19 2.0 43.810 Abbott Laboratories 18 1.9 45.711 Merck Research Laboratories 17 1.8 47.512 Agouron Pharmaceuticals 16 1.7 49.313 Boehringer Ingelheim

Pharmaceuticals 12 1.3 50.513 Pharmacia and Upjohn 12 1.3 51.815 Astra USA 10 1.1 52.915 Daiichi Pharmaceuticals 10 1.1 53.915 Janssen Research Foundation 10 1.1 55.015 Sandoz Pharmaceuticals 10 1.1 56.119 Amgen 9 1.0 57.019 GlaxoSmithKline 9 1.0 58.019 Schering-Plough 9 1.0 59.019 Triangle Pharmaceuticals 9 1.0 59.923 GERCOR 8 0.9 60.8

Diðer 180 sponsor 368 39.2 100.0Toplam 938 100.0

Geçen sayýmýzda “Clinicaltrials gov”dalistelenen klinik araþtýrmalarla ilgilibazý bilgileri aktarmýþtýk. Bu sayýda daayný s tede yer alan klinikaraþtýrmalarýn sponsorlara göredaðýlýmlarý ile ilgili bazý istatistiklerisunuyoruz.

i

46 ÝKU

ÝKU

7 adet protokolü devam eden 7 sponsor:

6 adet protokolü devam eden 7 sponsor:

5 adet protokolü devam eden 8 sponsor:

4 adet protokolü devam eden 10 sponsor:

3 adet protokolü devam eden 10 sponsor:

2 adet protokolü devam eden 29 sponsor:

Biocine; Chiron; Hoechst Marion Roussel; Immunobiology Research Institute; LederleLaboratories; Ligand Pharmaceuticals; Theradex

Corixa Corporation; Dupont Pharmaceuticals; Genta; Jacobus Pharmaceutical;MicroGeneSys; Newport Pharmaceuticals International; Ortho Pharmaceuticals

Anderson Clinical Research; Fisons; Immuno-US; Isis Pharmaceuticals; SequusPharmaceuticals; Trimeris; U.S. Bioscience; Vion Pharmaceuticals

Dupont Merck; G D Searle; Immune Response; Novartis Pharmaceuticals; OtsukaAmerica Pharmaceuticals; Parke-Davis; Sanofi Pharmaceuticals; SUGEN; SuperGen;Wyeth-Ayerst

AJI Pharma USA; Argus Pharmaceuticals; Celgene; Eli Lilly; Immunex Corporation;OXO Chemie; Shaman Pharmaceuticals; SmithKline Beecham; United Biomedical;VaxGen

Aeterna Laboratories; Biogen; Cell Therapeutics; Centaur Pharmaceuticals; Cytran; DirectTherapeutics; FeRx; Fujisawa Pharmaceutical; Genzyme; ICN Pharmaceuticals; IlexOncology; Immunomedics; Interferon Sciences; Intracel; Lederle-Praxis Biologicals; LifeTime Pharmaceuticals; LyphoMed; Oclassen Pharmaceuticals; Oxo Chemie GmbH;Proctor and Gamble; Prologue Research International; Protein Design Labs; R W JohnsonPharmaceutical Research Institute; Rhone-Poulenc Rorer; Romark Laboratories L.C.;Roxane Laboratories; Sarawak MediChem Pharmaceuticals; VIMRx Pharmaceuticals;Wyeth-Lederle Vaccines

1 adet protokolü devam eden 109 sponsor:

Adams Laboratories; Advanced Peptides; Alfacell; Alkermes; Allos Therapeutics; ALZA; AndrulisPharmaceuticals; Anthra Pharmaceuticals; Antigenics; Apex Bioscience; Apollon; Applied Immunesciences;Aronex Pharmaceuticals; AstraZeneca Pharmaceuticals; Avanir Pharmaceuticals; Aventis Pharmaceuticals; Aviron;Baker Norton Pharmaceuticals; Barr Laboratories; Berlex Laboratories; Biochem Pharma; Biocodex; BioCrystPharmaceuticals; Boehringer Mannheim; Britannia; Burroughs Wellcome; Cell Pathways; CellegyPharmaceuticals; Centocor; Chimeric Therapies; Clinical Solutions; Cochlear; Columbia Research Laboratories;Connaught Laboratories; CTL ImmunoTherapies Corporation; Curis; CytRx; DEKK-TEC; Dendreon;Discovery Laboratories; EDAP Technomed; Elan Pharmaceuticals; Enzon; Esai; Eyetech Pharmaceuticals; FreeRadical Sciences; GEIGY Pharmaceuticals; Genelabs; Genetics Institute; Genitope; HEM Research; Hollis-Eden Pharmaceuticals; Inex Pharmaceuticals; Inflexxion; INO Therapeutics; InSightec-TxSonics; InterMunePharmaceuticals; Janssen Pharmaceutical; Janssen Pharmaceutica-Washington University Fund; LexigenPharmaceuticals; Liposome; LXR Biotechnology; Matrix Pharmaceutical; Medsearch; Merieux Institute; Miles;Mucos Pharma GmbH and Co; Mylan Laboratories; Neurex; Neurochem; Neurocrine Biosciences; NexstarPharmaceuticals; North American Biologicals Inc; Novogen; Novum; Oncotech; Onyvax; Ortho Dermatologics;Parexel; Pasteur Merieux Connaught; Peregrine Pharmaceuticals; PharmaResearch; PPD Development; ProVantage; Procept; Pro-Neuron, Inc.; Purdue Frederick; QLT PhotoTherapeutics; Quintiles; Ribozyome; RobertsPharmaceutical; Roche Laboratories; Sangstat Medical Corporation; SciClone Pharmaceuticals; SeronoLaboratories; Sigma-Tau Pharmaceuticals; SkyePharma; Somerset Pharmaceuticals; Stolle Milk BiologicInternational; Therakos; Tularik; Unimed Pharmaceuticals; United Therapeutics; Univax Biologics Inc; Vical;ViroLogic; ViRx; Warner Lambert - Parke Davis; Zarix

47ÝKU

Yaþ grubu Toplam Hasta alýmýdevam eden

Çocukluk çaðý (0-17 yaþ) 3083 1734Eriþkin çað (18-65) 5499 3274Yaþlýlýk (+66) 4602 2815

Klinik araþtýrmalarýn yaþ gruplarýna göre daðýlýmý

(Clinicaltrials.gov'dan alýnmýþtýr)

Faz Toplam Hasta alýmýdevam eden

Faz I 1117 721Faz II 1814 1333Faz III 985 590Faz IV 81 51

Klinik araþtýrmalarýn fazlarýna göre daðýlýmý

(Clinicaltrials.gov'dan alýnmýþtýr)

Kurum Toplam Hasta alýmýdevam eden

Amerikan Ulusal Saðlýk Enstitüsü (NIH) 4354 2593Diðer Amerikan Federal Kurumlarý 284 165Endüstri 813 179Üniversite ve diðer kurumlar 2083 1753

Klinik araþtýrmalarýn sponsorlarýna göre daðýlýmý

(Clinicaltrials.gov'dan alýnmýþtýr)

K. A. D. Haberler