imun. situac. amocana

1. 8 wlis biWs dausves mwvave limfoblasturi leikemiis diagnozi. pacientis ujredebi

Sefasda MHC II klasis antigenebis, CD19, CD34 receptorebis mixedviT. yvela es

markeris xasiaTdeboda. malignizirebuli ujredebis imunofenotipis dasadgenad

gamoiyenes fluorescenciis maRali doniT. maT aseve hqondaT citoplazmuri mZime

jaWvi. ganviTarebis romel stadiaze imyofebian es ujredebi?

1.umwifari B ujredebi

2.limfoiduri winamorbedi ujredebi

3.momwifebuli B ujredebi

4.pre B-ujredebi

2. 8 wlis biWis sisxli gamoikvlies citometriiT. ujredebi damuSavebuli iyo

fluoroqromiT moniSnuli antisxeulebiT, romlebic sxvadasxva ujreduli

markerebis sawinaaRmdegod iyo mimarTuli. qvemoT CamoTvlilTagan romeli

markerebis mixedviT unda moxdes B limfocitebis gansazRvra?

1. CD3

2. CD4

3. CD19

4. CD56

3. 18 wlis kolejis gundis wevrma mimarTa Terapevts. gamovlinda sunTqvis

Sezღudva. radiografiulad aRmoCnda 15 sm mediastinaluri grova. periferiuli

sisxlis TeTri ujredebis 80% iyo aranomaluri patara limfocitebi. am

aranormaluri ujredebis imunofenotipirebam maTze CD4+ da CD8+

1

receptorebis arseboba aCvena. Cveulebrivad organizmSi sad SeiZleba iqnes

aRmoCenili es ujredebi?

1. Zvlis tvinSi

2. periferiul sisxlSi

3. Timusis korteqsSi

4. Timusis medulebSi

4. 12 wlis bavSvs dausves T-ujreduli limfomis diagnozi. malignizirebuli ujredebis

fenotipi iyo iseTive, rogoric normaluri winamorbedi ujredebis, romlebic

tovebdnen Zvlis tvins da gadadian TimusSi. qvemoT CamoTvlilTagan romeli

zedapiruli markerebi eqnebaT malignizirebul ujredebs?

1. CD4-, CD8-, TcR-

2. CD4-, CD8-, TcR+

3. CD4-, CD8+, TcR+

4. CD4+, CD8-, TcR+

5. HSV (martivi herpes virusi aris ukiduresad warmatebuli paTogeni, radgan

mas aqvs imunuri pasuxisagan Tavis aridebis mravali meqanizmi. magaliTad,

HSVI da HSVII tipebi inficirebuli ujredebis zedapirze MHCI klasis molekulebis

eqspresias Trgunaven. qvemoT CamoTvlilTagan romel koreceptorTan

dakavSireba SeiZleba daiTrgunos am meqanizmiT?

1. CD2

2. CD4

3. CD8

4. CD16

6. 6 wlis biWs Cautarda limfuri jirkvlebis biofsia, ris Sedegadac gamovlinda

kortikul midamoSi limfocitebis Semcirebuli ricxvi. misi periferiuli

7. sisxlis leikocitebSi savaraudod romeli membranuli receptoris matarebeli

ujredebis raodenoba iqneba normaluri an momatebuli?

1. CD2

2. CD3

3. CD4

4. CD19

8. 65 wlis qals, romelic mohyva avtoavariaSi, Cautarda spleneqtomia. qvemoT

CamoTvlilTagan romeli paTogenis mimarT eqneba mas momatebuli

mgrZnobeloba am operaciis Semdeg?

2

1. Babesia microti

2. Bordetella pertussis

3. Corynebacterium diphteriae

4. enteroagregatuli Escherichia coli

9. 4 wlis biWi, savaraudo imunologiuri problemebis mizeziT miiyvanes

samedicino daxmarebis centrSi. laboratoriuli gamokvlevebiT bavSvis

periferiul sisxlSi gamovlinda sisxlis TeTri ujredebis ukiduresad momatebuli

raodenoba, Rrma limfocitoziT. cervikaluri limfuri kvanZebis biofsiiT

dadasturda ukiduresi hipocelularoba orsave kortikul da parakortikul areSi.

qvemoT CamoTvlilTagan leikocitebis romeli zedapiruli molekulebis

ararsebobam SeiZleba gamoiwvios aseTi klinikuri suraTi?

1. adresinebis

2. imunoglobulinebis ojaxis adheziuri molekulebis mqone ujredebis

3. integrinebis

4. L-seleqtinebis

10.6 wlis bavSvs kisris midamoSi, ukana zedapirze aReniSneboda Semkvriveba,

romelsac araviTari anTebis niSnebi ar hqonda da palpaciiT arc Tu rbili iyo.

msgavsi Semkvriveba sxvagan arsad ar isinjeboda. aRniSnuli aridan aRebuli

biofsiuri masalis analiziT dadginda, rom aRniSnuli masa aris limfuri jirkvali

kortikuli midamos ujredebis mniSvnelovnad momatebuli raodenobiT. qvemoT

CamoTvlilTgan romeli zedapiruli markerebi SeiZleba gamovlindes

fluoroqromiT moniSnuli antisxeulebis saSualebiT?

1. CD2

2. CD3

3. CD4

4. CD19

11.radiaqtiuri kvalis efeqtis mqone saRebavi Seyvanil iqna sacdeli subieqtis

winamxris midamoSi kanqveS. qvemoT CamoTvlilTagan limfuri kvanZis romel

nawilSi gamomJRavndeba pirvelad radiaqtiuroba?

1. korteqsi

2. medula

3. parakorteqsi

4. kafsulisqveSa sinusebi

3

12.arkanzasSi kurdRelze monadires dausves tularemiis diagnozi. mas

mkurnalobdnen streptomiciniT. erTi kviris Semdeg igi dabrunda klinikaSi

temperaturasa da kanze gamonayarze CivilebiT, magram aRar aReniSneboda

tularemiuli papula, limfadenopaTia da baqteremia. daniSnuli medikamentis

SewyvetisTanave simptomebi gaqra. ra rols TamaSobda streptomicini am

SemTxvevaSi?

1. igi moqmedebda rogorc B-ujredebis mitogeni

2. igi moqmedebda rogorc hapteni

3. igi moqmedebda rogorc superantigeni

4. igi moqmedebda rogorc imunogeni

13.II msoflio omis dros qinins iyenebdnen rogorc malariis saprofilaqtiko

saSualebas. aRsaniSnavia, rom samxedro pirTa erT nawils aReniSneboda

cxeleba (qininiT damuSavebuli eriTrocitebis komplementiT ganpirobebuli

hemolizisiT gamowveuli) Tirkmlebis qronikuli autoimunuri dazianeba

14.. ra rols TamaSobda am SemTxvevaSi qinini?

1. autoantigenis;

2. mtareblis;

3. haptenis;

4. imunogenis;

15.ori wlis bavSvs, romelsac awuxebda SebrunebiTi baqteriuli infeqciebi,

daudginda imunodeficiti; mas Tavis asakTan normaSi hqonda CD19+ da CD3+

ujredebis ricxvi periferiul sisxlSi da aReniSneboda ukiduresi neitrofilia.

nitrolurji tetarzoliumis saRebavis Semcirebis testi iyo normaluri. ra defeqti

SeiZleba hqondes am pacients?

4

1. CCR4-is ukmarisoba (qemokinis receptori)

2. leikocitebis adheziis deficiti

3. il-1-is ukmarisoba

4. il-4-is ukmarisoba

16.2 wlis biWi miiyvanes saavadmyofoSi savaraudo imunologiuri problemebis

gamo. mis avadmyofobis istoriaSi mravaljer iyo aRniSnuli Staphylococcus,

Pseudomonas da Candida-s gvaris sokoebiT gamowveuli kanis infeqciebi. bavSvis

obieqturi gamokvlevisas dadginda cervikaluri limfadenopaTia da saSualo

simZimis hepatosplenomegalia. sisxlis testebma gamoavlina eriTrocitebis

sedimentaciis siCqaris mateba da neitrofilia. negatiuri iyo nitrolurji

tetrazoliumis saRebavis reduqciis testi da aseve neitrofilebis oqsidaciis

indeqsi. ra SesaZlo defeqti SeiZleba hqondes am bavSvs?

1. CD3-is ukmarisoba

2. mieloperoqsidazis ukmarisoba

3. NADPH oqsidazis ukmarisoba

4. fagocituri granulebis struqturebis defeqti

17.cxovelebSi Seiswavles, rom antigenis Seyvanisas, upiratesoba eniWeba

araspecifikuri anTebis ganviTarebas. qvemoT CamoTvlili nivTierebebidan

vaqcinaSi romeli maTganis damateba gamoiwvevs neitrofilebis mizidvas

dazianebul midamoSi.

1. komplementis komponenti 3b

2. IgG

3. mieloperoqsidaza

4. il-8

18.Micobacterium leprae-iT gamowveuli adamianis infeqciuri paTologiebi klinkuri

gamovlinebebis farTo speqtriT xasiaTdeba, rac ujredSida mikroorganizmze

makroorganizmis mier ganxorcielebuli imunuri pasuxis xangrZlivobasa da

intensiurobaze damokidebulebiT aixseneba, rasac Tan mosdevs sakuTari

qsovilebis dazianeba. granulomebis mqone pacientebSi aRiniSneba il-2,

interefon-, TNF-s Semcvelobis momateba. imunuri sistemis romeli ujredebia

pasuxismgebeli am citokinebis warmoqmnaze?

1. citotoqsiuri T-limfocitebi

2. epiTeluri ujredebi

3. Th-1 ujredebi

4. Th-2 ujredebi

5

19.damtkicebulia, rom imunuri meqanizmi, romlic gansazRvravs keTris or

gansxvavebul formas Soris SerCevas, damokidebulia antigenis wardgenis

formasa da imunuri pasuxis ganviTarebis procesSi adamianebs Soris

individualur gansxvavebebze. Tu antigenis amocnobis sawyis etapze izrdeba

il-4-is, il-5-is, il-6-is da il-10-is produqcia, savaraudod

viTardeba lepromatozuli keTri, rasac Tan axlavs warumatebeli Senelebuli tipis

hipermgrZnobelobis reaqciis ganviTareba. lepromatozuli keTrisTvis

damaxasiaTebel romel sadiferenciacio

maCvenebels unda gansazRvravdes lepromatozuli dazianebis kerebSi il-4-is,

il-5-is, il-6-is da il-10-is Warbi produqcia?

1. autoimunurobas

2. hipergamagloubulinemias

3. dauyovnebeli hipermgrZnobelobas

4. anTebas

23.10 Tvis gogona miiyvanes saavadmyofoSi Pneumocystis carini-iT gamowveuli

pnevmoniiT. mis periferiul sisxlSi CD19+ receptoris mqone ujredebis

raodenoba Sesabamisi iyo asakTan, magram CD3+ da CD4+ receptorebis

mqone ujredebis raodenoba iyo Semcirebuli. Sratis eleqtroforeziT

gamovlinda hipogamaglobulinemia. mis periferiuli sisxlis limfocitebis

proliferacia fitohemaglutinsa da alogenur ujredebze sapasuxod normalurad

mimdinareobda. Sereuli limfocitebis reaqciaSi stimulatorad gamoyenebuli

misi ujredebi alogenuri T-limfocitebis proliferacias ar iwvevda. qvemoT

CamoTvlilTagan romeli ukeT aRwers molekulebs, romlis ararsebobac

aRiniSneba mis limfocitebze?

1. molekulebi, romlebic ukavSirdebian endogenurad miRebul peptidebs

2. molekulebi, romlebic ukavSirdebian egzogenurad miRebul peptidebs

3. SesaZlebeli es molekulebi iyos 2 mikroglobulinebi

4. es molekulebi unda arsebobdnen sxeulSi arsebul yvela birTvian ujredze

20.diabetiT daavadebul xandazmul mamakacs quslis midamoSi ganuviTarda

bebera, romelic dainficirda. miuxedavad imisa, rom yoveldRiurad eqTani

usufTavebda da antibiotikis Semcveli malamoTi mkurnalobda Wrilobas, mainc

adgili hqonda temperaturis matebas, hipotenzias da dazianebuli midamos

irgvliv gamonayaris ganviTarebas. zemoT CamoTvlili klinikuri simptomebis

gamomwvevi mikroorganizmis toqsini ra meqanizmiT SeiZleba iwvevdes

amgvar dazianebas?

6

1. moqmedebdes rogorc il-1-is homologi

2. iwvevdes B-limfocitebis poliklonur gaaqtiurebas

3. aaqtiurebdes komplements

4. gverdidan akavSirebdes MHCII molekulasa da TcR-s da iwvevdes

ujredebis poliklonur gaaqtiurebas

21.mravalricxovan eqsperimetebSi Seswavlilia, rom T-limfocitebis proliferacia da

diferenciacia simsivnuri ujredebis sapasuxod sustia, radgan simsivnur

ujredebs ara aqvT limfocitebis aqtivaciisTvis saWiro Tanamastimulirebeli

molekulebi. im SemTxvevaSi, Tu melanomiT daavadebuli pacientis ujredebSi

Tanamastimulirebeli molekulebis eqspresias uzrunvelyofen, SesaZlebeli

gaxdeba simsivnis sawinaaRmdego imunuri pasuxis aRZvra. simsivnuri

ujredebSi transfeqciisTvis qvemoT CamoTvlilTagan romeli molekulebis

gamoyeneba iqneba yvelaze efeqturi?

1. B7

2. CD2

3. CD28

4. LFA-1 (T-ujredis molekula, romelic ukavSirdeba ICAM-1 APC-ujredze)

22.B-limfocitebis SeswavlisaTvis laboratoriuli kvlevebisaTvis iyeneben

antisxeulebis mza diagnostikumebs. isini ar aaqtiureben ujredebs da ar

iwveven kepings. qvemoT CamoTvliTagan romeli antisxeulis diagnostikumia

yvelaze ufro Sesaferisi?

1. monoklonaluri anti-CD19 IgG

2. monoklonaluri CD56 IgG

3. papainiT damuSavebuli anti-CD19 IgG

4. papainiT damuSavebuli CD56 IgG

23.sisxlis A jgufis mqone piridan gamoyofili IgM izohemaglutininebi d

24.

25.aamuSaves pepsiniT. rodesac am reaqciis produqts daumates sisxlis B-jgufis

mqone piris eriTrocitebs, isini SesaZloa:

1. aglutinirdnen

2. ganicadon lizisi

3. fagocitirdnen

4. araviTari efeqti ar miviRoT

7

26.26 wlis qals, romelmac miakiTxa sameano ganyofilebas, aReniSneboda

orsulobis I trimestris manZilze temperatura da limfadenopaTia. mis periferiul

sisxlSi gamovlinda Toxoplasma gondii-s sawinaaRmdego antisxeulebis mzardi

titri. misi axalSobili iyo drouli da amasTanave saSvilosnos Sida infeqciis

araviTari niSani ar hqonda. parazit-specifiuri imunofermentuli analiziT romeli

klasis imunoglobulini

unda gamovlindes axalSobilebSi mwvave infeqciis diagnostirebisaTvis?

1. IgA

2. IgD

3. IgG

4. IgM

27.4 wlis biWs aReniSneboda imunodeficitis simptomebi. mas stanjavda

lorwovani garsebis ganmeorebadi infeqciebi da sabavSvo standartuli

vaqcinaciebis mimarT damcvelobiTi imunuri pasuxi dagvianebiT

uviTardeboda. misi Sratis imunoeleqtroforeziT ar gamovlinda

makroglobulinebis (IgM) piki da naxvelSi ki sekretoruli IgA. gamWoli

citometriiT dadginda monomeruli IgM-is matarebeli B-limfocitebis normaluri

raodenoba da SratSi monomeruli IgA-s normaluri done, IgR da IgG-s oTxive

qveizotipi aseve normaSi iyo. qvemoT CamoTvlilTagan romeli faqtorebis

deficits SeiZleba mivakuTvnoT es paTologiuri mdgomareoba:

1. CD40-is ar arsebobas

2. J-jaWvis ar arsebobas

3. il-4-is ar arsebobas

4. Tdt-s ar arsebobas

28.56 wlis usaxlkaro, loTi da cxelebis mdgomareobaSi myofi mamakaci

usaxlkaroTa TavSesafarSi gatarebuli mZime xvelebis Setevis Semdeg

gadaudebeli daxmarebis centrSi miiyvanes. samedicino punqtSi misvlisas

aReniSneboda Cqari pulsi, sunTqvisas adgili hqonda difuzuri gamonayofis

gamomuSavebas. endotraqealuri aspiraciisas amoRebuli iqna lorwovan-

Cirqovani gamonayofi, romelic Seicavda mravalricxovan "gram+" kokebs

Zewkviseburi ganlagebiT. mis SratSi iyo Str. pneumoniae-s polisaqariduli kafsulis

mimarTspecifiuri IgM-is maRali titri. qvemoT CamoTvlilTagan romeli efeqtoruli

meqanizmi monawileobs IgM-is adre

29.ul produqciasTan erTad infeqciis winaaRmdeg?

8

I paneli

A B

DC

CD

3

II paneli

A B

DC

CD

3

1. ADCC (antibody-dependent cell-mediated cytotoxicity)

2. komplementiT ganpirobebuli opsonizacia


4. LAK-ujredebi

30.3 wlis biWs ramdenimejer daudginda pnevmonia, romelTa drosac gamoyofili

iyo Str.pneumoniae. yovel jerze mas umkurnales peniciliniT da mdgomaroeba

gaumjobesda. amJamad igi Sefasebulia, rogorc imunodeficitis statusis mqone

piri. Sratis eleqroforeziT gamovlinda imunoglobulinebis yvela izotipis asakTan

Sesabamisi normaluri done, magram SratSi komplementis zogierTi

komponentis done Semcirebuli iyo. qvemoT CamoTvlilTagan romeli faqtoris

ukmarisobas SeiZleba gamoewvia msgavsi problema?

1. C1

2. C2

3. C3

4. C5

31.melanomis eqsperimentuli mkurnaloba moicavs simsivne-specifikuri kilerebis

in vitro stimulacias simsivnuri ujredebiT, romlebSic Secvlili-sakuTari MHCI

klasis molekulebis maproducirebeli genis transfeqcia moaxdines. I etapze

pacientis periferiuli sisxlis leikocitebi, romlebic CD4-is CD8-isa da CD20-is

mimarT gamomuSavebul fluoroqromiT moniSnul antisxeulebTan inkubirdeba.

Semdeg ujredebs gamWoli citometriiT ikvleven da mimdinareobs

gansxvavebuli ujreduli markerebis eqspresiis mixedviT maTi dayofa

populaciebad. qvemoT naCveneb romel kvadratSi SeiZleba aRmovaCinoT

simsivnis sawinaaRmdego imunuri pasuxis ganmapirobebel ujredTa

subpopulacia:

1. I paneli A kvadrati

2. I paneli B kvadrati

3. I paneli C kvadrati

4. I paneli D kvadrati

5. II paneli A kvadrati

6. II paneli B kvadrati

7. II paneli C kvadrati

8. II paneli D kvadrati

CD 8

9

32.62 wlis buRalters ganuviTarda myari simsivne, romelic ar eqvemdebareboda

qimioTerapias. is CaerTo eqsperimentul mkurnalobaSi, romlis farglebSic

sakuTari imunuri efeqtoruli ujredebis stimulacias awarmoebdnen

malignizirebuli ujredebis amocnobisa da lizisis mizniT. aRmoaCines, rom

simsivnur ujredebze ar eqspresirdeboda MHCI klasis antigenebi. am

simsivnuri ujredebis in vitro romeli citokiniT damuSaveba aRZravs yvelaze ufro

efeqtur imunur pasuxs, am ujredebis pacientSi reinfuziis Semdeg?

1. IFN-

2. il-2

3. il-8

4. il-10

33.Toxoplasma gondii aris ujredSida paraziti, romelic cxovrobs rogorc fagocitebSi,

aseve aramafagocitirebel ujredebSi da maTSi warmoqmnis u

jredSida vezikulebs. es saSulebas aZlevs mas Tavi daaRwios CD8+

limfocitebis mier amocnobasa da kvlas, romlisTvisac saWiroa CD8+

limfocitebisaTvis ucxo peptidebis wardgena im MHC molekulebis mier

omelTac aqvT:

1. 2 domeni 2 mikroglobulinis nacvlad

2. peptidis damakavSirebeli Rari (naprali)

3. mxolod erTi transmembranuli domeni

4. ori msgavsi jaWvi

34.1960 wlamde gadidebuli Timusis jirkvlebis mqone bavSvebs ukeTdebodaT

radikaluri manipulaciebi (amokveTa), radgan misi roli jer kidev cnobili ar iyo.

am SemTxvevaSi mTeli darCenili sicocxlis ganmavlobaSi ra paTologiuri

mdgomareoba SeiZleba ganviTarebuliyo?

1. simsivnze imunuri kontrolis daTrgunva

2. neitrofilebis mier Jangbad-damokidebuli kvlis daTrgunva

3. antigenze pirveladi pasuxis CaxSoba

4. alergenebis mimarT mgrZnobelobis gazrda

35.aSS-Si Zmis mosanaxuleblad Casuli 42 wlis nigerieli mamakaci moxvda

hospitalSi. bolo Tveebis manZilze mas aReniSneboda wonis sagrZnobi kleba,

CD 20

10

Ramis oflianoba, naxvelis saSualo donis produqcia sisxlis minarevebiT. kanis

PPD testi aRmoCnda pozitiuri. ra daskvnis gamotana SeiZleba am Sedegebze

dayrdnobiT?

1. saqme gvaqvs ujreduli imunuri pasuxis formirebasTan

2. saqme gvaqvs humoruli imunuri pasuxis formirebasTan

3. B-ujreduli sistema defeqturia.

4.neitrofilur fagocituri sistema defeqturia.

36.pacients aReniSneboda limfadenopaTia da splenomegalia. misi limfocitebis

raodenoba iyo Zlier momatebuli, Trombocitebisa ki – Semcirebuli, aseve mas

hqonda autoimunuri anemia. T ujreduli mitogenis stimulaciiT periferiuli sisxlis

leikocitebi, mitogenuri stimulis moxsnis Semdegac ki, kvirebis ganmavlobaSi

intensiur proliferacias ganicdidnen,. qvemoT CamoTvlilTagan romelia yvelaze

SesaZlo mizezi am genetikuri defeqtisa?

1. komplementis ar arseboba

2. Fas-is ararseboba

3. IFN--s ar arseboba

4. perforinebis ararseboba

37.1970 wlamde Sesiebuli tonzilebis mqone bavSvebs utardebodaT

tonzileqtomia. am radikalurma manipulaciam dakarga mniSvneloba mas

Semdeg, rac Seswavlil iqna lorwovanTan asocirebuli limfoiduri qsovilis (MALT)

mniSvnelovani roli damcvelobiT imunur pasuxSi. romeli imunoglobulinis

produqcia xdeba MALT-is mier?

1. dimeruli imunoglobulini sekretoruli komponentiT

2. placentaSi gamavali monomeruli imunoglobulini

3. poxier ujredebze dakavSirebuli monomeruli imunoglobulini

4. komplmenetis gamaaqtiurebeli pentameruli imunoglobulini

38.adamianebs sicocxlis ganmavlobaSi utardebaT gegmiuri tetanusis toqsoidis

ineqcia. 10 wlis intervaliT ganmeorebiTi dozis Seyvanisas, qvemoT

CamoTvlilTagan am antigenze mopasuxe B-limfocitebis Sesaxeb romeli

Sexedulebaa swori?

1. maT receptorebs unda hqondeT maRali avidoba

2. maTi unda hqondeT adheziuri molekulebis dabali done

3. maT unda hqondeT zedapiruli IgG, IgM, IgE

4. maT unda hqondeT zedapiruli IgM.

11

39.64 wlis mamakacs Cautarda radikaluri operacia 18 mm zomis nawlavis

adenokarcinomis diagnozis safuZvelze. rodesac amoRebuli qsovili da

mezenteruli limfuri kvanZebi gamoikvlies paTanatomiurad, gamovlinda

hiperplazirebuli peieris folaqebi IgA-s masakretirebeli plazmuri ujredebiT.

magram TviT sekretoruli-IgA ar iqna aRmoCenili nawlavis sanaTurSi. qvemoT

CamoTvlilTagan nawlavebis epiTeliumSi ganviTarebulma romelma

paTologiurma cvlilebebma SeiZleba axsnas es movlena?

1. izotipis gadarTvis defeqtma

2. variabeluri domenis genis–segmentis gadawyobis defeqtma

3. J-jaWvis sinTezis unaris dakargvam

4. poliimunoglobulinuri receptoris dakargvam

40.imunologiur laboratoriebSi swavloben limfocitebis sxvadasxva

subpopulaciebis migraciis gzebs. patara, dayofis unars moklebuli limfocitebis

erTi populacia, romelsac aqvs CD3+ da CD4+ receptorebi, xasiaTdeba il-2-is

receptoris dabali da LFA-1-is receptoris maRali eqspresiis done, sxeulSi

migraciis procesSi kvalis datovebis mizniT moniSnulia radiaqtiuri markeriT.

qvemoT CamoTvlilTagan romeli ujredebi iniSneba am SemTxvevaSi?

1. blasturi ujredebi

2. mexsierebis T-ujredebi

3. gaaqtivebuli T-ujredebi

4. efeqtoruli T-ujredebi

41.10 wlis biWs ukbina mawanwala (usaxlkaro) ZaRlma, ris safuZvelzec

gaukeTda antirabiuli imunoglobulini. ras gamoiwvevs antirabiuli

imunoglobulinis ganmeorebiTi Seyvana?

1. anti-alotipuli antisxeulebis warmoqmnas

2. epitopis sawinaaRmdego antisxeulebis warmoqmnas

3. idiotipis sawinaaRmdego antisxeulebis warmoqmnas

4. cofis sawinaaRmdego antisxeulebis warmoqmnas

42.CikagoSi erT-erT samedicino centrSi yvela rezidents kunTSi Seuyvanes A

tipis H3N2 gripis preparati. qvemoT CamoTvlilTagan romeli tipis imuniteti

Camoyalibdeba?

1. SeZenili

2. xelovnuri aqtiuri

12

3. xelovnuri pasiuri

4. bunebrivad pasiuri

39. qalaqis dasufTavebis sanitaruli samsaxuris muSaks daejaxa manqana, ris

Sedegadac dauzianda qveda kiduri. ukiduresad mZime travmis gamo aucilebeli

gaxda muxlis qvemoT amputacia. miuxedavad imisa, rom pacientis anamnezSi

aRniSnuli iyo 6 wlis win tetanusis sawinaaRmdego revaqcinaciis Sesaxeb, mas

mainc Seuyvanes adamianis antitetanusis imunoglobulini dazianebuli qsovilebis

irgvliv midamoSi. qvemoT CamoTvlilTagan imunizaciis romel formas

miekuTvneba imunoglobulinis am tipis administracia?

1. SeZenils

2. xelovnuri aqtiurs

3. xelovnuri pasiurs

4. bunebrivi aqtiurs

40. 28 wlis kaci gamoZaxebuli iqna sasamarTloSi SvilisaTvis savaldebulo

yovelTviuri Tanxis gadauxdelobis braldebiT. 20 wlis deda amtkicebda, rom igi iyo

misi Svilis mama. sasamarTlom miiRo gadawyvetileba bralis damtkicebamde

Catarebuliyo qalis, mamakacisa da bavSvis sxvadasxva genetikuri testi. erT-erTi

testi iyo imunoglobulinebis genetikuri identifikacia. romeli imunoglobulinuri

markeri iqneboda gamoyenebadi am SemTxvevaSi?

1. alotipi

2. idiotipi

3. IgA

4. izotipi

41.epidemiuri meningitis prevenciisaTvis 1998 wels SeimuSaves axali vaqcina,

romelic gankuTvnilia bavSvTa asakisaTvis. is Seicavs Haemophilus influenzae B-

tipis kafsulis polisaqaridsa da daxocil, srul Bordetella pertussis baqteriebis

narevs. ra roli aqvs am vaqcianSi arsebul daxocil, srul baqteriebs?

1. mtarebelis

2. haptenis

3. mitogenis

4. adiuvantis

13

42.axalSobili, romelsac aReniSneboda piris damajinxebuli forma, ganuviTarebeli

yurebi da Tvalis Wrilebis daSorebuli (farTo) ganlageba, Sefasda

imunologiurad. rentgenologiuri gamokvleviT dadginda kardialuri

ganuviTarebloba da Timusis Crdilis ararseboba. qvemoT CamoTvlili

parametrebidan romeli SeiZleba hqondes normaSi am bavSvs?

1. parazituli samizneebis mimarT antisxeul-damokidebuli ujreduli

citotqsiuroba

2. virusiT inficirebuli samizneebis mimarT citotoqsiuri sikvdili

3. mafagocitirebel ujredebSi Jangbadis metabolitebis

warmoqmna

4. konkanavalin A-ze proliferaciuri pasuxi

43.14 Tvis axalSobili biWi miiyvanes specialistTan imunodeficitis gamo. oTxi Tvis

win bavSvs kvlav ganumeorda baqteriuli infeqcia. imunuri pasuxis

gamowvevis mizniT gamoyenebuli iqna pnevmokokuri vaqcina, ramac Sedegi

ar gamoiRo. periferiuli sisxlis Seswavlam gamoavlina mitogenze (PWM)

pasuxismgebeli ujredebis ar arseboba. Zvlis tvinis aspiraciiT gamovlinda B-

ujredebis winamorbedebis (pro-B) momatebuli raodenoba. qvemoT

CamoTvlilTagan romeli diagnozia yvelaze swori?

1. agamaglobulinemia

2. Cveuli variabeluri hipogamaglobulinemia

3. dijorjis sindromi

4. viskot-oldrijis sindromi

44.31 wlis mamakacs bolo 5 wlis manZilze Cautarda mkurnaloba Neisseria

gonorrhoeae-iT gamowveul urogenitaluri infeqciis meoTxe SemTxvevis gamo.

mis anamnezSi ar aRiniSneboda sxva etiologiuri agentiT gamowveuli

Sebrunebuli an uCveulo infeqciis epizodebi. savaraudod

qvemoT CamoTvlilTagan romeli imunologiuri deficiti aReniSneba am

pacients?

1. C8 deficiti


3. IgA-s SerCeviTi deficiti

4. mwvave kombinirebuli imunodeficiti

45.pacienti samjer iqna hospitalizirebuli ganmeorebadi abdominaluri mtkvneuli

edemis gamo, ris Semdegac man kvlav miakiTxa samedicino daxmarebis

14

centrs tuCebis Sesiebis gamo. qvemoT CamoTvlilTagan ra SeiZleba

aReniSnebodes am pacients?

1. T-ujredebis aranormaluri funqcia

2. T-ujredebis aranormaluri raodenoba

3. neitrofilebis defeqturi qemotaqsisi

4. C4-is Semcirebuli done

46.4 wlis gogonas aReniSneboda S.aureus-iT gamowveuli abscesi. mis anamnezSi

aRsaniSanvia aseve Serratia marcescens-iT gamowveulSi winamorbedi infeqcia.

romeli fermentis ukmarisoba SeiZleba aReniSnebodes am pacients?

1. adenozin deaminaza

2. C1-inhibitori

3. mieloperoqsidaza

4. NADPH-oqsidaza

47.pediatrs mimarTa 4 wlis biWis dedam, radgan mis Svils aReniSneboda

warsulSi kanis mravlobiTi dazianebebi xelze. mas mkurnalobdnen

antibiotikebiT, ris Semdegac es simptomebi alagda. bavSvis anamnezSi

Canda, rom mas Catarebuli hqonda misi asakisTvis gaTvaliswinebuli yvela

imunizacia. pediatris mier moTxovnili laboratoriuli kvlevebis Sedegebi ase

gamoiyureboda:

imunoglobulinebis done – normaluri

B- da T- ujredebis raodenoba - normaluri

komplementis done – normaluri

kalciumis da paraTiroidis hormonis done – normaluri

nitrolurji tetrazoliumis testi – uaryofiTi.

dedam amcno Terapevts, rom egzemis an sisxlCaqcevebis problemebis

mxriv aqamde aranairi problemebi ar hqonda.

1. X-SeWiduli agamaglobulinemia

2. qronikuli granulomatozuri daavadeba


4. mwvave kombinirebuli imunodeficituri daavadeba

48.2 wlis biWi hospitalizirebuli iqna S.aureus-iT gamowveuli mwvave pnevmoniis

niSnebiT, romelic Sesabamis mkurnaobas daeqvemdebara. pacientis

anamnezSi aRsaniSnavi iyo baqteriuli infeqciebis SemTxvevebi warsulSi. man

gadaitana wiTela 6 Tvis win. gamokvlevebiT gamovlinda tonilaruli qsovilis

simcire da limfadenopaTiis niSnebis ararseboba. imunoeleqtrofereziT

15

gamovlinda gamaglobulinis normaze mcire Semcveloba. nitrolurjis

tetrazoliumiT da qemiluminescenturi SefasebiT gamovlinda mafagocitirebeli

ujredebis normaluri funqcia. qvemoT CamoTvlilTagan risi defeqti SeiZleba

iyos am bavSvis amJamindeli mdgomareobis mizezi?

1. adenozin deaminazas ukmarisoba

2. Btk-genis defeqti (bruto

3. WAS-genis defeqti

4. ICAM-1-is naklovaneba

49.2 wlis biWi, romelsac aReniSneboda lorwovan garsebze anTebiTi kerebis

gaCena, gansakurTebiT tuCebis midamoebis dazianebiT, miiyvanes pediatriul

klinikaSi. komplementis romeli komponentis cvlileba dafiqsirdeba am

pacientSi?

1. C4-is daqveiTeba

2. C1-is daqveiTeba

3. C1-is momateba

4. C1, C4 da C2-is momateba.

50.27 wlis orsulma miakiTxa prenataluri zedamxedvelobis centrs, sadac

Cautarda rutinuli kvlevebi aiv-is antisxeulebze. EIA-iT gamovlinda, rom RPR-ze

pacienti iyo negatiuri, aiv-ze ki – pozitiuri. vestern blotingis meTodiT

gamovlinda antisxeulebis arseboba aiv p24 antigenis mimarT. ra saxis rCeva

unda mieces am pacients?

1. aiv-iT inficirebulia rogorc deda, aseve nayofi

2. aiv-ze deda pozitiuria

3. aiv-ze dedas unda Cautardes PCR

4. es Sedegi aiv-ze mcdaria

51.aiv-ze pozitiuri dedis axalSobili aucilebelia rom Sefasdes aiv-ze. qvemoT

CamoTvlilidan romeli meTodis Catareba iqneba ufro sando?

1. CD4 ujredebis daTvla

2. EIA - aiv-is as-is aRmoCenisaTvis

3. PCR aiv-is genomis aRmosaCenad

4. p120 antigenis Sefaseba

52.aiv-is mimagreba Th-ze iwyeba gp120-is molekulebis CD4 receptorebze

adheziiT. Semdeg etapze gp 120 ganicdis konformaciul cvlilebebs da

16

ukavSirdeba sxva molekulas. qvemoT CamoTvlilidan romelia CD4 receptoris

Tanakoreceptori, romelic ikavSirebs limfotropul aiv-s?

1. T-ujredebze eqspresirebuli qemokinis receptori CXCR4

2. T-ujredebze eqspresirebuli qemokinis receptori CXCR5

3. B-ujredebze eqspresirebuli komplementis receptori CR2(CD21)

4. T-ujredebze eqspresirebuli citokinis receptori CCR5

53.egzotikuri cekvebis profesionali mocekvave (san-franciskoSi) 10 wlis

manZilze iTvleba avi-pozitiurad. am drois manZilze igi araregularulad iRebda

antiretrovirusul preparatebs, romlebic Sidsis klinikaSi hqonda gamowerili

(mcire Semosavlis gamo). morigi gamokvlevisaTvis klinikaSi misvlis mometSi

CD4-ujredebis raodenoba aRmoaCnda 390ujr/mm3 dabla. qvemoT

CamoTvlilidan romeli imunologiuri parametri daiTrguneba am infeqciis

mocemul etapze?

1. PWM mitogenze ujredebis proliferacia

2. Candida-s antigenze Senelebuli tipis hipermgrZnobeloba

3. IgA-s produqcia

4. baqteriebis ujredSida sikvdili

54.aiv-iT inficirebul pacientSi imunur pasuxis TH2-isken gadaxris tendencia dros

daavadebis mimdinareobis procesSi SedarebiT adreul periodSi aRiniSneboda.

pacientSi, romelsac aqvs CD4-is raodenoba 500/mm3 qvemoT CamoTvlilidan

romeli citokinebi iqneba gazrdili?

1. IFN-

2. il-1

3. il-2

4. il-10

55.43 wlis qali aReniSneboda saxsrebis Sesieba da tkivili saxsrebis areSi,

kanqveSa kvanZebis arseboba, marcxena muxlis zomaSi momateba.

sasaxsre C

anTidan amoRebuli iqna 100 siTxe. am siTxis gamokvlevisas, qvemoT

CamTvlilidan romeli maTgani SeiZleba gamovleniliyo?

1. aqtivirebuli T-limfocitebi

2. antisxeulebis IV tipis kolagenis mimarT

3. antisxeulebi DNA-is ormagi Zafis mimarT

4. IgG-Fc ubnis sawinaaRmdego IgM klasis antisxeulebi

17

56.36 wlis fermeri samuSao procesSi ramodenimejer dazianda suros SxamiT, ris

Sedegadac kanis daziznebebi ganuviTarda. dReisaTvis cnobilia, rom dnm

rekombinantuli teqnologiebis gamoyenebiT farmacevtuli kompaniebi

xelovnurad qmnis citokinebs da uSvebs maT malamos saxiT. qvemoT

CamoTvlilidan romeli citokini unda daeniSnos am pacients, rom daiTrgunos

am reaqciis simwvave?

1. -interferoni

2. il-2

3. il-3

4. il-10

57.1960 wlebSi Sistomis endemiur keraSi momuSaveebi dasnebovdnen am

umartivesebiT. maTSi Sistomis ganviTarebis Wiis stadiaze myofi

gamomwvevis sapasuxod gamomuSavdeboda IgG klasis antisxeulebi da maTi

sisxlSi gadasvlis da cirkulaciis stadiis dadgomisas pacientebs aReniSnebodaT

mwvave da zog SemTxvevaSi sasicocxlo safrTxis mqone cxeleba, edemis

ganviTareba, arTralgia da gamonayari. qvemoT CamoTvlilidan romeli

paTologiis dros xdeba msgavsi imunologiuri meqanizmiT imunuri pasuxis

ganviTareba?

1. artiusis reaqcia

2. atopiuri alergia

3. gudpasCeris sindromi

4. tuberkulinze reaqcia

58.axalgazrda axladdaqorwinebulma qalma miakiTxa Terapevts "memkvidruli

problemebis" gamo, romelic mas dedisgan hqonda gadmocemiT gagonili.

problema imaSi mdgomareobda, rom mis dabadebamde misi da(Zma)

daibada Tumca garegnulad normaluri, Tavad pacienti daibada cianozuri,

laqebiT dafaruli, dasWirda mravalricxovani transfuziuri manipulaciebi

mdgomareobis stabilizaciamde. dedis Semdgomi orsulobebi dasrulda

mkvdradSobadobiT. pacienti moeloda msgavsi problemebis ganviTarebas

sakuTari orsulobis ganmavlobaSi. sisxlis testebis analiziT, savaraudod,

qvemoT CamoTvlilidan ra daskvnis gamotana SeiZleba?

1. qmari gamokvleuli unda iqnes Rh Tavsebadobaze

2. is aris RhD- da mSobiarobis Semdgom unda imkurnalos Rho GAM-

3. is aris RhD+ da mSobiarobis Semdeg unda imkurnalos Rho GAM-

4. is aris RhD+ da araviTari riski nayofisTvis ar arsebobs

18

59. egvipteSi adgilobrivi populaciis warmomadgenlebSi, gansakuTrebiT ki

bavSvebSi xSiri iyo Schistosoma mansoni-iT invazia, ramdenadac sarwyavi arxebi

warmoadgenen rezervuars am parazituli WiisTvis da bavSvebi banaobdnen

Trxrilebsi. kanqveS gamomwvevis SeWrisas, sawyis etapze warmoiqmneboda

Sistomulebi, romelTa hemodinamikaSi moxvedris da cirkulaciis etapze momwifeba

xdeba mezenterul venebSi. Sistosomulebis etapobrivi sikvdilis Sedegad kanze

ramodenime wuTSi viTardeba intensiuri qavili, mCxvletavi tkivilis niSnebiT da

urtikaria. qvemoT CamoTvlilidan romeli reaqciis gamovlenaa es simptomebi?

1. artiusis reaqciis

2. kontaqturi dermatitis

3. Sratismieri daavadebis

4. I tipis hipermgrZnobelobis

60. 42 wlis profesiiT meqanikoss daudginda Tirkmlis paTologiis ukiduresi stadia.

mas hyavda tyupi Zmebi, romlebic MHC-is yvela lokusis mixedviT identurebi

iyvnen. maT gamoTqves donorad gaxdomis survili. ra ewodeba am tipis

transplantants?

1.autotransplantanti

2.heterotransplantanti

3.sinerguli transplantanti

4.qsenotransplantanti

61. mwvave mielogenuri leikemiis mqone pacients Cautarda sxivuri da

qimioTerapia. daigegma dedmamiSvilidan Zvlis tvinis gadanergva. 9 Tvis

Semdeg ganviTarda generalizebuli gamonayari, kanis aqercva, siyviTle da

sisxliani diarea. Zvlis tvinis meore, genetikurad ufro axlo myofi donoridan

miiCnies rom transplantacia iqneboda warumatebeli da 10 Tvis Tavze pacienti

daiRupa. qvemoT CamoTvlilidan romeli imunuri efeqtoruli meqanizmTan aris

asocirebuli am tipis transplantantis mocileba?

1.makrofagebis aqtivaciasTan

2.antisxeulebisa da komplementis sistemis aqtivaciasTan

3.CD8+ limfocitebis aqtivaciasTan

4.NK-s aqtivaciasTan

62. 45 wlis mamakacs ganuviTarda rqovanas wyluli da saWiro gaxda rqovanas

transplantacia. ra saxis premedikacia unda Cautardes qirurgiuli manipulaciis

warmatebis mizniT?

19

1.daeniSnos kortikosteroidebi, mag., prednizoloni

2.daeniSnos ciklosporini A, mTeli sicocxle

3.daeniSnos mitozuri inhibitorebi, mag., ciklofosfamidi mTeli sicocxle

4.aranair mkurnalobas ar saWiroebs

63. bavSvisTvis, romelsac sWrdeboda Tirkmlis gadanergva, SeTavazebuli iqna

sami dedmamiSvilis da orive mSoblis Tirkmeli. cxrilSi warmodgenilia maTi

(savaraudo donorebis da recipientis) Sereuli limfocitebis reaqciaSi stimulaciis

indeqsebi. es ukanaskneli aris eqsperimentuli jgufisa da uaryofiTi kontrolis

jgufis limfocitTa proliferaciis(izomeba I3HI) - Timidinis CarTvis mixedviT)

maCveneblebis fardoba. romeli iqneba saukeTeso savaraudo donori?

gamomsxivebeli mastimulirebeli ujredebi

mopasux

e

ujredebi

recipienti ma

ma

I

dedmamiSv

ili

II

dedmamiSv

ili

ded

a

III

dedmamiSv

ili

recipienti 1,0 4,1 1,1 8,3 2,3 8,5

mama 5,3 1,0 5,6 4,9 12,

5

5,9

deda 3,2 12,

6

4,5 3,9 1,0 4,8

I

dedmam.

1,6 6,5 1,0 4,4 5,5 6,0

II

dedmam.

7,6 5,9 4,4 1,0 4,9 7,8

III

dedmam.

9,0 5,7 7,0 8,9 4,4 1,0

1.mama

2.deda

3.I dedmamiSvili

4.II dedamiSvili

64. gulisa da filtvis transplantaciisas (eqsperimentuli mkurnaloba) pacients

mkurnalobdnen anti-CD28 antisxeulebis Fab fragmentebiT transplantaciis

procesSi da erTi Tvis Semdeg imeorebdnen. ra aris amgvari Terapiis mizani?

1.T-ujredebis daSla

2.transplantirebuli qsovilebis mimarT anergiis induqcia

20

3.T-ujredebSi mitozis inhibireba

3.anTebis SeCereba

65. pacientis sxeulis dazianebuli ubnebidan biofsiiT mopovebuli iqna

malignizirebuli ujredebi da in vitro pirobebSi Seyvanil iqna GM-CSF-is

maproducirebeli geni da kvlav Canergvil iqna pacientSi. qvemoT CamoTvlilidan

romeli ujredebis mobilizeba mohyveba Sedegad amgvar mkurnalobas?

1.APC-ujredebis

2.NK-ujredebis

3.plazmuri ujredebis

4.T-limfocitebis

66. B-ujreduli limfomis diagnozis mqone pacients daudginda, rom malignizirebuli

ujredebi aproducirebdnen monomerul IgM-s. qvemoT CamoTvlilidan romeli

preparatis gamoyeneba iqneba ufro gamarTlebuli mxolod malignizirebuli

ujredebis daSlis mizniT?

1.CD3-is sawinaaRmdego antisxeulebi plus komplementi

2.anti-CD19 antisxeulebi plus komplementi

3.anti-CD20 antisxeulebi plus komplementi

4antiidiotipuri antisxeulebi plus komplementi

67.papilomavirusiT inficirebisgan da cervikaluri intraepiTeluri neoplaziisagan

maRali riskis qveS myofi populaciis dacvis mizniT, eqspermentulad iyeneben

rekombinantul dnm-vaqcinas. virusis genebi, romelic akodirebsa E6 da E7

proteinebs, SehyavT virusul veqtorSi da Semdgom es preparati

intramuskularulad SehyavT pacientSi. ra mizani aqvs amgvar mkurnalobas?

1.virusuli onkogenebis inaqtivacia

2.MHC I-is eqspresiis gazrda simsivnur ujredebi

3.bunebrivi ujreduli antionkogenebis dacva

4.CD8+ T-limfocitebis stimulacia.

68. ZuZus kibos progresirebadi formis diagnozis safuZvelze, qals Cautarda

radikaluri masteqtomia, rasac mohyva gegmiuri dasxiveba da qimioTerapia.

orwliani remisiis Semdeg Tavi iCina metastazurma keram da amis safuZvelze

man airCia eqspreimentuli mkurnalobis meTodi. am procesSi misi Zvlis tvinis

aspiraciul masalas GM-CSF-iT, TNF- da IL-2-iT amuSavebdnen da Semdeg isev

ukan SeyavdaT. qvemoT CamoTvlilidan romeli ujredebi warmoadgenen amgvari

damuSavebis samiznes?

21

I paneli

1.B-limfocitebi


3. NK-ujredebi

4. TH1-ujredebi

69. 6 wlis bavSvi zimbabvedan aSS-is onkologiur centrSi miiyvanes berketis

limfomis diagnoziT. malignizirebuli ujredebis analizma gamoavlina, rom am

ujredebs ar hqondaT MHC I klasis antigenebi. simsivnur keraSi rekombinantuli

dnm-is teqnologiiT miRebuli romeli citokinis Seyvana gazrdis am simsivnuri

ujredebis mgrZnobelobas CD8+ ujredebis mimarT?

1. IFN-

2. IL-1

3. IL-2

4. IL-10

70. qvemoT CamoTvlilidan aiv-infeqciaze eWvis SemTxvevaSi romeli testi unda

Catardes pirvel rigSi?

1.poliakrilamidis gelSi aiv-is antigenis eleqtroforezi

2.aiv-is antigeni kovalenturad dawyvilebaze RBC-Tan, pacientis Sratsai da

antiimunoglobulinze

3.aiv-antigenze, pacientis Sratze, antiimunoglobulinur Sratsa da

ferment-substratul ligandze

4.aiv-antigenzei, pacientis Sratzei, antiimunoglobulinur Sratsai da radiaqtiur

ligandze

71. pirdapiri kumbsis reaqcia Cautarda bavSvs gestaciis me-7 Tves. dedis

anamnezSi aRiniSneboda wina ori problemuri orsuloba da arc erTxel ar miuRia

Rho GAMTM. Terapevs eWvi hqonda fetalur eriTrobalstozze. qvemoT CamoTvlilidan

romeli ingredientia aucilebeli am proceduris Casatareblad?

1.dedis Srats damatebuli Rho GAM damatebuli kumbsis reagenti

2.dedis Srats damatebuli Rho RBCs damatebuli kumbsis reagenti

3.Rho GAM damatebuli Rh + RBCs bavSvidan

4.Rh + RBCs bavSvidan damatebuli kumbsis reagenti

72. pacientis, romelsac aReniSneboda Cediak-higaSis sindromi, periferiul sisxlSi

gamoikvlies NK-ujredebis raodenoba. misi periferiuli sisxlis leikocitebi

daamuSaves fluoroqromiT moniSnuli anti-CD3, anti-CD56 da anti-CD2

22

II paneli

A B

DC

CD

3

antisxeulebiT. romeli panelis romel meoTxedSi SeiZleba aRmoCenil iqnas NK-

ujredebi?

1.I paneli A kvadrati

2.I paneli B kvadrati

3.I paneli C kvadrati

4.I paneli D kvadrati

5.II paneli A kvadrati

6.II paneli B kvadrati

7.II paneli C kvadrati

8.II paneli D kvadrati

73. orive ABO sisxlis tipirebisa da kumbsis reaqciisas, romlebic hemolizuri

daavadebis aRmoCenisaTvis gamoiyeneba, axalSobilebSi, eriTrocitebis

Sewebeba (aglutinacia) iTvleba dadebiT pasuxad. ratom ar aris kumbsis

reagentis damateba ABO sisxlis tipirebisas aucilebeli etapi?

1. sisxlis glikoproteinebze pasuxSi yvela antisxeuli aris IgG

2. komplementiT ganpirobebuli lizisi ar aris mniSvnelovani ABO

SeuTavseblobaSi

3. kumbsis Srati sazRvravs mxolod anti Rh-antisxeulebs.

4. IgM pentamerebi sakmaod didia, rom TviTon moaxdinos

erTirocitebis uSualo aglutinacia.

5.kumbsis reagents araaucilebels xedis bunebrivi izohemaglutininebis

maRali titri.

74. axalgazrda qali, romelmac miakiTxa uSvilobis CiviliT reproduqtologs,

aRniSnavda 5-wliani qorwinebis manZilze unayofobas. kvlevis I safexuri iyo

Chlamidia trachomatis-ze saSvilosnos yelis nafxekis Semowmeba, romelsac SeuZlia

gamoiwvios falopis milebSi Sexorcebebi. qvemoT CamoTvlilidan romeli

laboratoriuli kvlevebi unda Catardes qlamidias antigenis aRmosaCenad am

nimuSSi.

1. pirdapiri mafluorescencirebadi antisxeulTa testi

2. imunofermentuli analizi

3. arapirdapiri mafluorescencirebadi antisxeulTa teqsti

CD 56

CD 20

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4. Wester blot (genetikuri kvleva)

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pasuxebi

1. D

2. D

3. C

4. A

5. C

6. E

7. A

8. E

9. E

10. E

11. B

12. C

13. B

14. D

15. C

16. D

17. C

18. B

19. D

20. A

21. A

22. A

23. E

24. B

25. B

26. C

27. D

28. A

29. A

30. B

31. A

32. D

33. A

34. D

35. D

36. B

37. A

38. B

39. C

40. A

41. D

42. D

43. A

44. B

45. E

46. D

47. B

48. B

49. B

50. D

51. C

52. B

53. B

54. D

55. E

56. E

57. A

58. E

59. E

60. D

61. C

62. E

63. C

64. B

65. A

66. D

67. D

68. D

69. A

70. D

71. D

72. ?

73. D

74. A

25

imun. situac. amocana

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