OB / Gyn – Urologycombined conference

主講者 : 湯夢彬 指導者 : 沈國壽 李之微 96-09-26

General data

Name: 張 x x Gender: Female Age: 31 years old Occupation: Radiological technician Date of admission: June 27. 2007 Date of discharge: July 05. 2007

OB / Gyn history

G1P0A0 Last menstrual period: Oct.08.2006 Expected date of delivery: July.15.2007 Endometriosis s/p laparoscopy on

Jul.09.2000

Present illness

First pregnancy on Oct. 2006.

Prenatal examination in OB/Gyn OPD. Mother and baby were normal.

Lower abdomen pain and vaginal bleeding at 4:30 AM on Jun. 27 2007 (GA 37 weeks 3 days)

Present illness

She was admitted to OB/Gyn ward at 7 AM on Jun. 27 2007 due to cervical os 3cm and uterus contraction by fetal monitor.

No fever, no vomiting, no abdomen rebounding pain.

Past and personal history

No hypertension No diabetes mellitus Deny other systemic diseases No food & drug allergy history No smoking No alcohol drinking No medication dependant / abuse Operation history: laparoscopy on July 2000

Physical examination

Conscious: Alert, GCS: E4M6V5

BP: 120/80 mmHg PR: 88/min

RR: 20/min BT: 36.6 C

BW / BL: 64.5 kg / 166 cm

HEENT: grossly normal

Chest: symmetric expansion, clear breathing sound

Heart: regular heart beat, no murmur

Abdomen: Ovoid compatible with Gestation AGE

Irregular uterine contraction

Extremity: move freely, no deformity, no edema

Fetal monitor : FHB variable, baseline 140 bpm.

NST : reaction.

Lab data

WBC: 14400 Hb: 12.8

Plt: 333000 Neut%: 84.4

Lymp%: 12.6 Mono%: 2.8

Glucose: 47 BUN: 6.0

Cr: 0.6 Na: 137

K: 4.2 Cl: 100

Impression and plan

Pregnancy at 37 weeks 3 days, in labor

1.Arrange childbirth in delivery room.

2.Monitor fetal heart beat and labor progression.

3.Prepare for vaginal delivery.

Hospital course

Day 1 14:00

Cervix dilate to 4 cm, but the fetal monitor show acute fetal distress.

Arrange emergent cesarean section after patient and family agree.

Epidural pain control (for 3 days)

Operation finding:

Meconium stain +++.

The umbilical cord wound one circle around neck and right shoulder of baby.

Day 1 14:38

Procreate female baby smoothly. Wt: 3100g, Ht: 49 cm. Blood loss 400 cc.

Day 2

Patient require to remove Foley catheter, because she can void urine by herself and can walk around.

Lab. show:

Blood WBC 17740, Hb 10.4

Urine protein 3+, RBC 60-99, WBC 10-20, OB 3+, red color.

Day 3

Urine show red color, but no dysuria.

Day 4

Urine routine:

protein 2+, RBC numerous

WBC 5-10, OB 3+, red color

Day 5 & Day 6

Patient complain left flank pain.

Still hematuria.

Consult Urologist

Check KUB, chest X-ray.

Check Sonogram, IVP and PV

IVP and PV (Day 6)

5 min 15 min

1. Tear of L't renal pelvis or L't upper ureter with extravasating of contrast media out to L't retroperitoneal space.

2. L't hydronephrosis and hydroureter.3. Intact of R't kidneys and its renal calyces,

pelvis and R't ureter without dilatation or filling defect found.

4. Well distension of urinary bladder without filling defect found and minimal residual urine.

CT scan of abdomen (Day 6)

1. Tear of posterio-inferior wall of extra-renal portion of L't renal pelvis, with extravasating contrast media in L't peri-renal space.

2. L't hydronephrosis and L‘t hydroureter.3. Post-partum enlarged uterus noted.

Arrange L't Percutaneus nephrostomy (PCN) under the fluoroscopic guidance (after IVP study)

L't Percutaneus nephrostomy (PCN)(Day 6)

1. Tear of infeior wall of the extra-renal portio of L't renal pelvis, with contrast media extravasating out to L't peri-renal extraperitoneal space.

2. L't hydronephrosis and L't hydroureter.3. L't PCN done successfully, with a 8 Fr pig-tail

drainage catheter placed in the L't renal pelvis with good drainage function.

Arrange cystoscopy tomorrow (Day 7) due to clear urine drained from PCN tube.

Finding of Cystoscopy

1.Protruding mucosa and few necrotic change over posterior wall of the bladder.

2.Can’t detect the ureteral orifices, bilateral.

3.Found stitches over left lateral posterior wall.

4.No blood clots retention. (clear urine)

Cystoscopic biopsy ~ Chronic cystitis

(inflammatory cell infiltration, interstitial edema, granulation tissue in lamina propria)

Discharge on Day 9

Keep Foley catheter 2 weeks

Keep PCN tube 4 ~ 6 weeks

Final diagnosis (Day 9)

1. Pregnancy at 37 weeks 3 days, in labor with acute fetal distress S/P Cesarean section.

2. Tear of posterio-inferior wall of extra-renal portion of L't renal pelvis.

(spontaneous ?)

3. Iatrogenic bladder injury.

尿道排泄造影術 (96-07-13)1. Normal bladder with grade I L't

vesicoureteral reflux.

2. The L't ureter within normal without obvious stricture.

Remove Foley catheter

Antegrade pyelography (96-08-06)

<PCN tube training for 4 days at home>

L't antegrade pyelogram performed via PCN tube

s/p L't PCN with normal appearance of L't renal calyces, pelvis and L't ureter, without extravasating of contrast media, no stricture of L't ureter or L't lower ureteral UVJ with free passage of contrast media into urinary

bladder without stasis.

Removal of L't PCN tube.

Discussion

Demerit of operation ?

Bladder stitches

~ IVP, CT scan, Cystoscopy Hydronephrosis, renal pelvic rupture

~ tumor, stone, infection, stricture ? Prenatal examination

~ no urinary signs/symptoms

Hemodynamic changes in normal

pregnancy

10 to 15 beat/min increase in heart rate

Hemodynamic and renal changes during

normal pregnancy Systemic hemodynamics

Increase in cardiac output Fall in vascular resistance and blood pressure Blood volume expansion

Renal function and electrolyte balance Increase in glomerular filtration rate Chronic respiratory alkalosis ~ progesterone Hyponatremia due to resetting of osmostat ~ 270

mosm/kg Increased ADH metabolism and polyuria in

selected women

Dilation of the upper urinary system is common during pregnancy.

~ physiologic

~ hormonal & mechanical factors

Colicky pain

~ stretch renal capsule

~ knee-chest position

“acute hydronephrosis of pregnancy”

~ abrupt increase in intraurethral and intrapelvic pressure

~ usually position of the uterus

~ more common on the right than left side (9:1) due to dextrorotation of the uterus by the sigmoid colon

<Complication of pregnancy 5th edition cherry & merkatz’s>

“Dystocia” associated with cephalopelvic disproportion, or breech presentation as in our case, could increase the extrinsic pressure on the lower ureter at the pelvic brim, leading to increased intrapelvic pressure and peripelvic extravasation of urine.

<South Med J. 1980 Jun;73(6)>

A less common result of upper urinary tract dilation is acute renal rupture!

A review of the literature determined that 17 cases of rupture of the collecting system and/or renal parenchyma during pregnancy have been reported.

<Mayo Clin Proc. 1991 Feb;66(2)> As expected, 14 of 17 occurred on

right side… One maternal death has been reported.

Spontaneous rupture of the urinary tract during pregnancy is rare; a review of the literature revealed only 25 cases, most commonly occurring in diseased kidneys.

Ruptures of the collecting system: 12. Ruptures of the renal parenchyma: 13. 21 were diagnosed during pregnancy in the

second and third trimester. 4 within the first 24 h postpartum.

<Br J Urol. 1995 Nov;76(5)>

To our review, rupture of the renal pelvis during pregnancy has been reported in 16 cases.

Renal benign tumor, hamartoma: 4 Structural or infectious disease: 5 No underlying condition: 7 Right kidney (14/16, 87.5%)

<Am J Perinatol. 2002 May;19(4)>

Evaluation & treatment

Patient is stable

~ Conservation management

~ Ureteral stenting +/- nephrostomy

~ Percutaneous tube placement into the urinoma

Unsuccessful / patient presents shock

~ Exploration with open repair

~ Nephrectomy

The End

Thanks your attention