Fibromyalgia
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Transcript of Fibromyalgia
- 1. 1|P a g e(FMS) (FMS) () - , , , , ( Depression), , - 2-4% 9:1 35 45 , fibro, " ", myo, algia ( Musculoskeletal) - ( Neuropsychiatric) , - , . . ,
2. 2|P a g e ( Chronic) , , ( Allodynia) - , , , , ( Tenderness) , , , , ( Muscle Twitching), ( Palpitation), FMS "Fibrofog" ( Cognitive Dysfunction) "Fibrofog" - ( Impaired Concentration), -( Shortand Long-term Memory Disorders), - ( short-term multi-task), ( Cognitive overload), ( Impaired Speed of Performance ) - (Diminished Attention Span) 3. 3|P a g e comorbid Conditions (FMS) , ( Diffuse non-dermatomal Paresthesias), ( Functional Bowel Disturbances), ( Irritable Bowel Syndrome), ( Genitourinary Symptoms) ( Interstitial Cystitis), , , (Myoclonic Twitches) (Hypoglycemia) FMS , , , - (Myofascial Pain) ( Temporomandibular Joint Disorder) - ( Rheumatoid Arthritis) (Systemic Lupus Erythematosus) 20-30% FMS (FMS) , ("central sensitization") ( threshold for pain) 4. 4|P a g e (FMS) chronic fatigue ( syndrome), ( irritable bowel syndrome) ( depression) FMS (1H-MRS) , , , (FMS) (Natural Analgesia) FMS (Restless Leg Syndrome) FMS D2/D3 1975 FMS ( Sleep patterns), ( Mood) 1992 FMS ( Cerebrospinal Fluid) Selective Serotonin Reuptake Inhibitors (SSRIs) 5. 5|P a g e Serotonin-Norepinephrine Reuptake Inhibitors (SNRIs) FMS IGF-1, (Cortisol), (Leptin) ( Neuropeptide Y) , FMS 1 1 ( MADD ) FMS , ( Cognitive Dysfunction) MADD (Ribose) FMS 6. 6|P a g e-- (Neuro-immunoendocrine disorder) FMS -- FMS Cerebral spinal Fluid , IL-6, IL-8 - ( Corticotropin-Releasing Hormone) FMS , FMS 1975 ... ... ( ) (FMS) , -, - ( biopsies), .. .. ... FMS ( differential diagnosis) , , , , ( ACR) 1990 7. 7|P a g eFMS ( tender points) , axial skeleton ( , , ) ACR 18 ( tender points) 11 (FMS) 4 - / / / 8. 8|P a g e (FMS) , - cognitive-behavioral therapy), , ( , , (cognitive-behavioral therapy) FDA (FMS) , 2007 , , 2008 , 2009 , Antidepressants FMS , , , , - (SSRIs) (SNRIs) , FMS , , 9. 9|P a g e , NSAIDs FMS 450 / , ( compulsive gambling and shopping) ( Cyclobenzaprine) , FMS ( Tizanidine) -2 , , , , FMS FMS - , FMS FMS 10. 10 | P a g e , , , () , , , (Massage Therapy) - , -3 - - 500 2000 FMS 200 800 - - S-adenosylmethionine (SAMe) 800 - - - ... NADH (Nicotinamide Adenine Dinucleotide) , 20 ( Blue-green Algae) , FMS , - - ( Trifolium pratense - Red clover) - 11. 11 | P a g e (FMS) Gabamax-SR 75, 75/150, 150 mg Revlin 75/150 Revlin-M 75/750 Neugaba 75, Gabanext 75 /150 Pregabin-Plus 150 PEVESCA PLUS , , , , , , , , , , , - , , , 150 mg ( ) 300 mg , , , , , , , , , 40-150 mg ( ) , , , , , , , , , , 60 mg (-Cyclobenza prine TRYPTOMER 10/25/75, TRIPTOP 10/25 10, , , 25, 75 mg , Boswellia Serrata DUTIN, NUDEP- 20, 30, 60 mg 20 )Tizanidine Pramipexole Ropinirole ( Passiflora Passionflower) FMS , , (Valeriana officinalis - Valerian) FMS - , 12. 12 | P a g e ( "brain fog") ( Chamomile) , ha (Griffonia Simplicifolia) 5-HTP , (Echinacea) - ( Boswellia Serrata) - FMS (Black currant seed oil) -