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Animal Disease ControlPrepared by: Noemi Diloy- Encarnacion, DVM, MVetEpi
Session objectives:
At the end of this topic, the participants should be able to:• Assess the importance of local diseases based on selected criteria;• Distinguish prevention, control and eradication; and• Describe the various strategies for animal disease control.
Disease control programs are essential for the reduction, elimination or eradication of animal and poultry diseases and the prevention of the introduction or outbreak of foreign or domestic diseases.
Definitions
Prevention- refers to measures designed to prevent disease occurrence.
Disease control- reduction of the prevalence of a disease to a level where it is no longer considered a major health and/or economic problem.
Goals are: o Reduce mortalityo Reduce morbidity
Disease elimination- this is the near eradication stage; it is the stage between disease control and disease eradication status. The goal is to reduce the disease to a level that it has become a minor health problem. WHO (1991) defines it as “reduction of prevalence to a level below one case per million population.”
Eradication- total elimination of a disease. Achieved by eliminating the reservoir or source of the agent, severing the transmission chain or making the hosts immune to the disease. WHO describes this stage as having “no further cases of a disease occurring anywhere, and continued control measures are unnecessary.”
How do you know a good disease control officer?
1. He/she knows how to make a “priority” list.2. He/she responds quickly3. He/she can mobilize the right persons for the task: diagnose, control, and monitor disease problems.4. He/she can control the disease with the least cost.
Choose the diseases to control
Public Health Significance Impact on the livestock industry1. What zoonotic diseases occur more
frequently?2. What zoonotic diseases cause severe
sickness in humans?3. Present mortality and morbidity rates
1. How easily is the disease transmitted from farm to farm?
2. What are the losses due to morbidity?3. What are the losses due to mortality?4. What are the effects on trade and
commerce?
Prioritization
Items are ranked in order based on their “perceived or measured importance or significance”. Make the best use of limited human and financial resources
A. Simplex: Group perceptions are obtained by the use of questionnaires.
B. Nominal Group planning: Panel of experts is formed and individual judgments must be tapped and combined to arrive at decisions which cannot be determined by one person.
C. Criteria Weighting Method: Mathematical process whereby participants establish a relevant set of criteria and assign a priority ranking to issues based on how they measure against the criteria. The calculated values do not necessarily dictate the final policy decision, but offer a means by which choices can be ordered.
Examples of Prioritization Techniques (Centers for Disease Control and Prevention)
DISEASE PRIORITIZATION TOOL
Score Co-eff
Total
DISEASE KNOWLEDGE - 10 criteria 0 1 2 3 4
Speed of spread None
Non
transmissible
Very slow Low level of
transmission within holdings
and unlikely between
holdings
Slow
Slow transmission
between holdings with
or without animal
movements
Medium
Rapid transmission between
holdings with or without
animal movements
High
Rapid transmission
between holdings
without animal
movements
2.5
Number of livestock species involved One ND or expected to be limited Limited
2 species
Medium
3 species11
High
4 species and over
2.5
Persistence of the infectious agent in the
environment
No
Never Found
Rare Occasionally found ND if unknown Constant Animal reservoir or
vector
Not removable from
the environment
2.5
Risk of spread to susceptible populations No
Not contagious
Low Transmissible direct
contact
ND if unknown Medium Indirect contact,
contagion
High
Airborne infection
2.5
Potential for silent spread None Negligible
Signs of infection easily
recognised and likely to
occur in animal under
supervision
Low
Signs of infection
easily recognised but
depends on the level
of supervision
Moderate
Specific diagnosis may be
difficult in one or more
species
High
Disease/infection not
likely to be detected
for some time
2.5
Wildlife reservoir and potential spread Negligible
No known
wildlife
reservoir
Minor Prevalence in remote
wildlife
Moderate Wildlife
reservoir: no direct
contact with humans
or domestic animals
Significant
Wildlife reservoir
Serious Wildlife
reservoir in close
contact with humans
and/or domestic
animals
2.5
Vector reservoir and potential spread None
No known
vector or
reservoir
Low
Competent vector(s) thought
to exist in the country but not
considered capable of
surviving and transmitting
infection
Medium
Competent vector(s)
exist in the country
but not considered
capable of surviving
and transmitting
infection
High
Competent vector(s) exist in
the country but not
considered capable of
surviving but could transmit
infection
Very High
Competent vector(s)
exist in the country
and is (are) capable
of surviving and
transmitting infection
2.5
Variability of the agent Negligible
One type,
stable
host/vector
Low
Few types, not mutating,
stable host/vector
Moderate
Few types, not
mutating, low host
specificity, stable
vector if any
High
Numerous types or mutating,
low host or vector specificity
Very High
Numerous types and
mutating, low host or
vector specificity
2.5
Understanding of fundamental
immunology
Fully
understood,
both humoral
and cellular
immunity
Fully understand humoral
immunity and partial
understanding of cellular
immunity
Partially understand
humoral and cellular
immunity
Partially understand humoral
immunity
None
Nothing known about
the immunology
2.5
Host-Pathogen interaction Fully
understand the
host-pathogen
interactions
Understand some aspects of
the host and pathogen
interactions
Partially understand
the host-pathogen
interactions
Little understanding of the
host-pathogen interactions
No information 2.5
IMPACT ON ANIMAL HEALTH AND WELFARE - 3 criteria
0 1 2 3 4
Disease impact on production None
Production not
affected
Very low
Some loss of production but
no major impact on income
Low
Production reduced
by less than 20%.
Major loss of income
Medium
Production reduced by more
than 20%. Major loss of
income
Severe
Production reduced
by more than 50%.
Major loss of income
and viability of
industry threatened
8.33
Duration of animal welfare impact None
No impact
Transcient
Impact less than 48 hours
Short Term
48 hours to 13 days
Medium term
15 days to 24 months
Permanent
Greater than 24
months
8.33
Proportion of animal affected suffering
pain/ injury/ distress as a result of the
disease
None
No animal
affected
Very low
<5% of animals suffer
serious impact
Low
6-20% of animals
suffer serious impact
Medium
21 to 50% of animals suffer
serious impact
Serious
>50% of animals
suffer serious impact
8.33
IMPACT ON PUBLIC HEALTH - HUMAN HEALTH - 6 criteria
0 1 2 3 4
Impact of occurence on human health None
Humans not
considered
susceptible to
infection
Mild
Symptoms mild, transcient
without lasting effects
Medium
Symptoms may
require time off work,
(1week) and/or
medical intervention
Serious Symptoms
often provoke medical
intervention, possible long
term health effects (>1
month). Extreme pain and
discomfort. Fatalities
uncommon
High
High case fatality
(>5%) and/or
permanent health
effects
4.16
Likelihood of occurrence None
Proven
impossibility of
transmission
to humans
through live
animals,
animal
products,
vectors or food
Extremely rare Probability
lower than 1/1000000
Occasional Occurs
at an incidence lower
than 1/10000
Regular Occurs at an
incidence lower than 1/1000
Frequent
Occurs at an
incidence higher than
1/1000
4.16
Impact of occurrence on food safety No
Not spread in
food
Negligible
Very low level of
contamination of food but
unlikely to cause problems
Low
Low level of
contamination and
can cause
disease/infection if
organisms ingested in
large numbers
Medium Probability of spread
via food but large numbers of
organisms needed to cause
problems. Precautions
required
High
High probability of
spread via food, small
infective dose and
strict precautions
required
4.16
Transmissibility (spread from animal to
human)
No
No
transmission
possible
Negligible
No known transmission to
humans or no information
Low
Possible transmission
and existing contacts
with live animals
Medium
Possible transmission or
contamination through direct
or indirect contact or
vector/food
High
Very low species
barrier, possible
airborne or through
the environment
4.16
Spread in humans No
Non-
transmissible
Negligible
No known transmission
between humans or no
information
Low Transmission
between humans is
uncommon
Moderate Transmission
between humans requires
prolonged or high level
challenge
Rapid
Transmission
between humans
occurs frequently and
is common
4.16
Bioterrorism potential None
Agent
unavailable or
impossible to
handle or no
harm
Negligible
Agent available but difficult
to handle or low potential
harm
Low
Agent available and
easy to handle by
pros and labs but low
potential harm
Medium
Agent available and easy to
handle by pros and labs and
high potential harm
Severe
Agent available and
easy to handle by
individuals and high
potential harm
4.16
IMPACT ON WIDER SOCIETY - 3 criteria
0 1 2 3 4
Economic direct impact (including
cumulative costs (e.g. Enzoonotic vs
Epizootic))
None
No loss, no
control
measures
Negligible
Minor reduction in production
Low
Production reduced
but not banned.
Treatment and
vaccination
Medium
Production reduced and
partially banned. Test and
slaughter
High
Production reduced
and banned. Total
slaughter
8.33
Economic indirect impact (social,
market)
None
Products
continue to be
distributed
Negligible
Minor impact on distribution
of products
Low
Herd products
redirected to lower
value markets
Medium
Market price reduced
temporarily by less than 30%
High
Reduction by more
than 30% over a
month or a country
wide ban
8.33
Agriterrorism potential None
Agent
unavailable or
impossible to
Negligible
Agent available but difficult
to handle or low spread or
low economic damages
Low
Agent available and
easy to handle by
professionals and
Medium
Agent available and easy to
handle by professionals and
labs and rapidly spread or
Severe
Agent available and
easy to handle by
individuals and rapidly
8.33
handle or no
spread
labs but low spread or
low economic
damages
high economic damages spread and great
economic damages
IMPACT ON TRADE - 4 criteria 0 1 2 3 4
Impact on international trade due to
existing regulations
None
No restriction
or only at
animal level
Minor
Only at herd level
Moderate
At zone level and/or a
list of commodities,
no loss of official
status
Significant
Zone standstill, loss of
official status, short recovery
period
Serious
Possible nationwide
ban standstill with or
without list, official
atatus difficult to
recover
6.25
Impact on Economic trade due to
existing regulations
None
No restriction
or only at
animal level
Minor
Only at herd level
Moderate
At zone level and/or
list of commodities
Significant
At zone level and/or no list of
commodities
Serious
Nationwide
ban/standstill with or
without list
6.25
Potential for zoning High
Zoning
possible at
farm level
Moderate
Zoning possible 1 to 10 kms
Low
Zoning possible but
more than 10 kms
Very low
Zoning using wider
administrative boundaries
None
Only compartments
6.25
Impact on security of food supply Extremely
limited,
anecdotal
Low value
Only in some remote areas
Moderate
Someremote areas
may be temporarily
out of stock
High
Some areas of the country
may be out of stock
Very High
May cause or
increase hunger
problems
6.25
CONTROL TOOLS - 3 criteria 2 1 0 -1 -2
Appropriate diagnostics Need: Yes
Availability: No
Market
Potential: Low
Need: Yes
Availability: No
Market Potential: Yes
Need: Yes
Availability: Yes (not
fully effective)
Market Potential: Low
to Medium
Need: Yes
Availability: Yes (not fully
effective)
Market Potential: Yes
Either Need: No
or Need: Yes
Availability: Yes (fully
effective)
Market Potential: Yes
16.6
6
Appropriate vaccines Need: Yes
Availability: No
Market
Potential: Low
Need: Yes
Availability: No
Market Potential: Yes
Need: Yes
Availability: Yes (not
fully effective)
Market Potential: Low
to Medium
Need: Yes
Availability: Yes (not fully
effective)
Market Potential: Yes
Either Need: No
or Need: Yes
Availability: Yes (fully
effective)
Market Potential: Yes
16.6
6
Appropriate pharmaceuticals Need: Yes
Availability: No
Market
Potential: Low
Need: Yes
Availability: No
Market Potential: Yes
Need: Bacteria - Yes
Need: Virus -
Desirable
Availability: Bacteria -
Yes (not fully
effective)
Availability: Virus - No
Market Potential: Low
to Medium
Need: Yes
Availability: Yes (not fully
effective)
Market Potential: Yes
Either Need: No
or Need: Yes
Availability: Yes (fully
effective)
Market Potential: Yes
16.6
6
TOTAL
Source: http://www.discontools.eu/
Estimate the monetary value
Cost of disease Cost of disease control
Benefits of disease control
Costs due to mortalitycosts due to morbidityCosts associated with treatmentExtra labor to nurse the sick animalsProhibition of sales of animal products (ex. milk)Increase in food conversion indexImpact on trade
Diagnostic testsVaccinesDrugsTravel costsStaff costsVehiclesEquipmentGenetic loss due to the slaughter policyetc.
Benefit =
Losses due¿ the diseasewithout control project−Losses due¿ the disease withcontrol project=¿
RATIONALE FOR ESTABLISHING A DISEASE CONTROL PROGRAM
Justification for the disease control program, summarizing the current knowledge about the epidemiological situation within an area, providing detailed information on:
1. the disease situation
2. disease impacts (animal and public health, food safety, food security, biodiversity and socioeconomic impact) and how these are distributed among stakeholders
3. identity, level of interest and involvement of stakeholders
CONTROL PROGRAM GOALS
Goals are the desired results or outcomes that a control program envisions, plans and commits to achieve.
Examples:
a. Improve control of swine respiratory diseases in Bulacan.
b. Control and management of surra in the Philippines will contribute to increasing agricultural productivity and incomes, improving livelihoods and ensuring food security.
Sample guide for setting goals in animal health [Table adopted from (World Organisation for Animal Health, 2014)]
CONTROL PROGRAM OUTCOME, OUTPUTS, ACTIVITIES
Outcome is what had previously been termed “objective/s”. However the current approach is to have only one outcome defined in one brief statement which describes the change that the project is expected to generate in the target group. The outcome is the result of outputs which are the result of activities.
Outcome ___________
Output 1. ___________ Activity 1.1. __________Activity 1.2. __________
Output 2. ___________
Activity 2.1. __________Activity 2.2. __________
Output 3. ___________Activity 3.1 __________
Etc.
Outcome and outputs should be formulated in very clear terms that are qualitatively and quantitatively verifiable so that relevant indicators can be easily derived for monitoring and evaluation purposes. Outputs are usually described as nouns and adjectives Activities are the actions that the project will carry out in order to obtain the outputs. Note the activities are usually described as verbs and adverbs.
Examples:
Outcome: The strategy program envisions the Philippines to control and manage surra by 2025 such that incidence would be nearly 0 by that date.
Expected Output: 1. Greater understanding on the epidemiology of surra
Corresponding Activities:
1. Training on surra surveillance
2. Conduct surveillance to establish true prevalence of surra.
RISKS AND ASSUMPTIONS
Risk assessment and management are essential in project planning not necessarily to avoid risks but to plan for them and to mitigate their impact on the project.
outline the key risks assessing their impact and probability describe how the risks will be monitored; explain whether there is a credible programme external to the project that addresses these risks (e.g.
to improve public sector standards and systems); and outline steps proposed within the project to address these risks and indicate if these steps have been
agreed with project partners.
VARIOUS STRATEGIES FOR ANIMAL DISEASE CONTROL
PREVENTION
1. On-Farm Biosecurity. The word is defined as measures adopted to keep diseases out of herds where they do not currently exist.
a. Isolation of new animals brought to the farmb. Restriction on movement of people, animals, and equipmentc. Use of safe feeds- Swill feeding can be dangerousd. Hygiene. Effective combination of cleaning and disinfection
2. Border controls to prevent the entry of animals, animal products and other potentially disease-causing products- at national, provincial, municipal or farm levels.
3. Regulation of importations- strict enough to prevent entry of exotic diseases but liberal enough to encourage legal importations.
4. Strict observance of export and import protocolsa. Pre-export testing, quarantine and animal health certification
b. Post-arrival inspection, testing and quarantine5. Inspection of persons and products arriving at airports and seaports6. Proper disposal of food wastes from international aircraft and ship.
a. Incinerationb. Deep burial
7. Vaccination8. Vector control9. Public awareness and communication
CONTROL
Strategies to reduce the magnitude of existing disease 1. Reduce contact rate
a. case finding & isolationb. contact tracing & quarantinec. behavior changed. “Resting” of farm or premises- length is not less than the survival time of the pathogen. FAO
recommends a minimum of 21 days. e. Slaughter of susceptible animals f. Closure of livestock markets and other congregations of susceptible species (e.g. livestock
auction markets, race meetings and livestock exhibit/shows)g. Removal of animals from areas with high insect population
2. Reduce infectiousness: treatment, vaccination3. Reduce susceptibility
a. Vaccination: Selective ( “ring vaccination”) or Total (“blanket” vaccination )b. immune globulin
5. Identify and control reservoir/source a. pest/vector control
a. Treatment or Destruction of breeding sitesb. Use of insecticidal sprays
b. environmental disinfection c. Surveillance- regular inspection of animalsd. Biological - Read the success story on eradication of New World screwworm fly (Cochliomyia
hominovorax) in the Americas and North Africa using the sterile insect release method (SIRM).
e. Ban swill feeding or cook swill6. Reduce prevalence of infectious sources
a. identify and control infectious sources a. Proper disposal of contaminated carcasses- deep burial or burning
7. Reduce duration of infectiousness: Treatment, Vaccination8. Increase herd immunity
a. Vaccinationb. Genetic improvementc. Improved husbandry
9. Public education- to inform people of the nature of the disease and of the restrictions in place.10. Contact tracing- trace forward and trace back11. Zoning- The designation of geographic areas in which specific disease control strategies is to be
carried out.
Vaccination Tips1. Choose the safe and correct antigenic type. 2. Maintain vaccine quality- no contamination, potency, etc.3. Follow the recommended vaccination coverage (preferably 70 %)4. Mark vaccinated animals5. Monitor proper storage temperatures for vaccines 6. Organize trained personnel into “clean” and “dirty” teams7. Remember that gathering different herds together in one vaccination station maybe convenient but
dangerous.8. Count your needles and bottles before and after vaccination.
ERADICATION
Strategies to eliminate selected organisms from a defined population.
Conditions for eradication1. Social acceptability of the proposed eradication strategies;2. Limited host range of the disease agent;3. Limited transmission mechanisms;4. Availability of reliable diagnostic tools that can even detect the pathogen in reservoirs
or carriers; and5. Effective method for destruction of agents in reservoirs
Source: (Smith 2005)
Strategies for Eradication
1. Cleaning, disinfection and rest period2. Animal treatments3. Treatment of products and by-products4. Culling5. Test and isolation6. Test and slaughter7. Depopulation/repopulation
a. Advantages of stamping outi. the most efficient method for the rapid elimination of diseaseii. It is often the most cost-effective. iii. The disease eradication campaign is shorteriv. Shorter waiting period before the country can be recognized as being free of the
disease and the export of livestock and animal products resumed.b. Factors to consider before implementing the “slaughter” strategy
i. Community acceptanceii. Availability of other strategiesiii. Immediate availability of resources
Writing an Animal Disease Control Plan Prepared by: Noemi Diloy-Encarnacion, DVM, MVetEpi
I. Identify five diseases present in your locality that will satisfy the following criteria.
Public Health Significance Impact on the livestock industry1. What zoonotic diseases occur more frequently?2. What zoonotic diseases cause severe sickness in humans?3. Present mortality and morbidity rates
1. How easily is the disease transmitted from farm to farm?2. What are the losses due to morbidity?3. What are the losses due to mortality?4. What are the effects on trade and commerce?
II. Rank the diseases based on their measured importance using the prioritization tool. Write the summary of scores in the table below.
DISEASES DISEASE KNOWLEDGE IMPACT ON ANIMAL HEALTH
AND WELFARE
IMPACT ON PUBLIC HEALTH
AND HUMAN HELATH
IMPACT ON WIDER SOCIETY
IMPACT ON TRADE
CONTROL TOOLS
TOTAL SCORE
1 2 3 4 5 6 7 8 9 10 1 2 3 1 2 3 4 5 6 1 2 3 1 2 3 4 1 2 3
1
2
3
4
5
Score Co-eff
Total
DISEASE KNOWLEDGE - 10 criteria 0 1 2 3 4
Speed of spread None
Non
transmissible
Very slow Low level of
transmission within holdings
and unlikely between
holdings
Slow
Slow transmission
between holdings with
or without animal
movements
Medium
Rapid transmission between
holdings with or without
animal movements
High
Rapid transmission
between holdings
without animal
movements
2.5
Number of livestock species involved One ND or expected to be limited Limited
2 species
Medium
3 species11
High
4 species and over
2.5
Persistence of the infectious agent in the
environment
No
Never Found
Rare Occasionally found ND if unknown Constant Animal reservoir or
vector
Not removable from
the environment
2.5
Risk of spread to susceptible populations No
Not contagious
Low Transmissible direct
contact
ND if unknown Medium Indirect contact,
contagion
High
Airborne infection
2.5
Potential for silent spread None Negligible
Signs of infection easily
recognised and likely to
occur in animal under
supervision
Low
Signs of infection
easily recognised but
depends on the level
of supervision
Moderate
Specific diagnosis may be
difficult in one or more
species
High
Disease/infection not
likely to be detected
for some time
2.5
Wildlife reservoir and potential spread Negligible
No known
wildlife
reservoir
Minor Prevalence in remote
wildlife
Moderate Wildlife
reservoir: no direct
contact with humans
or domestic animals
Significant
Wildlife reservoir
Serious Wildlife
reservoir in close
contact with humans
and/or domestic
animals
2.5
Vector reservoir and potential spread None
No known
vector or
reservoir
Low
Competent vector(s) thought
to exist in the country but not
considered capable of
surviving and transmitting
infection
Medium
Competent vector(s)
exist in the country
but not considered
capable of surviving
and transmitting
infection
High
Competent vector(s) exist in
the country but not
considered capable of
surviving but could transmit
infection
Very High
Competent vector(s)
exist in the country
and is (are) capable
of surviving and
transmitting infection
2.5
Variability of the agent Negligible
One type,
stable
host/vector
Low
Few types, not mutating,
stable host/vector
Moderate
Few types, not
mutating, low host
specificity, stable
vector if any
High
Numerous types or mutating,
low host or vector specificity
Very High
Numerous types and
mutating, low host or
vector specificity
2.5
Understanding of fundamental
immunology
Fully
understood,
both humoral
and cellular
immunity
Fully understand humoral
immunity and partial
understanding of cellular
immunity
Partially understand
humoral and cellular
immunity
Partially understand humoral
immunity
None
Nothing known about
the immunology
2.5
Host-Pathogen interaction Fully
understand the
host-pathogen
interactions
Understand some aspects of
the host and pathogen
interactions
Partially understand
the host-pathogen
interactions
Little understanding of the
host-pathogen interactions
No information 2.5
IMPACT ON ANIMAL HEALTH AND WELFARE - 3 criteria
0 1 2 3 4
Disease impact on production None
Production not
affected
Very low
Some loss of production but
no major impact on income
Low
Production reduced
by less than 20%.
Major loss of income
Medium
Production reduced by more
than 20%. Major loss of
income
Severe
Production reduced
by more than 50%.
Major loss of income
and viability of
industry threatened
8.33
Duration of animal welfare impact None
No impact
Transcient
Impact less than 48 hours
Short Term
48 hours to 13 days
Medium term
15 days to 24 months
Permanent
Greater than 24
months
8.33
Proportion of animal affected suffering
pain/ injury/ distress as a result of the
disease
None
No animal
affected
Very low
<5% of animals suffer
serious impact
Low
6-20% of animals
suffer serious impact
Medium
21 to 50% of animals suffer
serious impact
Serious
>50% of animals
suffer serious impact
8.33
IMPACT ON PUBLIC HEALTH - HUMAN HEALTH - 6 criteria
0 1 2 3 4
Impact of occurence on human health None
Humans not
considered
susceptible to
infection
Mild
Symptoms mild, transcient
without lasting effects
Medium
Symptoms may
require time off work,
(1week) and/or
medical intervention
Serious Symptoms
often provoke medical
intervention, possible long
term health effects (>1
month). Extreme pain and
discomfort. Fatalities
uncommon
High
High case fatality
(>5%) and/or
permanent health
effects
4.16
Likelihood of occurrence None
Proven
impossibility of
transmission
to humans
through live
animals,
animal
products,
vectors or food
Extremely rare Probability
lower than 1/1000000
Occasional Occurs
at an incidence lower
than 1/10000
Regular Occurs at an
incidence lower than 1/1000
Frequent
Occurs at an
incidence higher than
1/1000
4.16
Impact of occurrence on food safety No
Not spread in
food
Negligible
Very low level of
contamination of food but
unlikely to cause problems
Low
Low level of
contamination and
can cause
disease/infection if
organisms ingested in
large numbers
Medium Probability of spread
via food but large numbers of
organisms needed to cause
problems. Precautions
required
High
High probability of
spread via food, small
infective dose and
strict precautions
required
4.16
Transmissibility (spread from animal to
human)
No
No
transmission
possible
Negligible
No known transmission to
humans or no information
Low
Possible transmission
and existing contacts
with live animals
Medium
Possible transmission or
contamination through direct
or indirect contact or
vector/food
High
Very low species
barrier, possible
airborne or through
the environment
4.16
Spread in humans No
Non-
transmissible
Negligible
No known transmission
between humans or no
information
Low Transmission
between humans is
uncommon
Moderate Transmission
between humans requires
prolonged or high level
challenge
Rapid
Transmission
between humans
occurs frequently and
is common
4.16
Bioterrorism potential None
Agent
unavailable or
impossible to
handle or no
harm
Negligible
Agent available but difficult
to handle or low potential
harm
Low
Agent available and
easy to handle by
pros and labs but low
potential harm
Medium
Agent available and easy to
handle by pros and labs and
high potential harm
Severe
Agent available and
easy to handle by
individuals and high
potential harm
4.16
IMPACT ON WIDER SOCIETY - 3 criteria
0 1 2 3 4
Economic direct impact (including
cumulative costs (e.g. Enzoonotic vs
Epizootic))
None
No loss, no
control
measures
Negligible
Minor reduction in production
Low
Production reduced
but not banned.
Treatment and
vaccination
Medium
Production reduced and
partially banned. Test and
slaughter
High
Production reduced
and banned. Total
slaughter
8.33
Economic indirect impact (social,
market)
None
Products
continue to be
distributed
Negligible
Minor impact on distribution
of products
Low
Herd products
redirected to lower
value markets
Medium
Market price reduced
temporarily by less than 30%
High
Reduction by more
than 30% over a
month or a country
wide ban
8.33
Agriterrorism potential None
Agent
unavailable or
impossible to
Negligible
Agent available but difficult
to handle or low spread or
low economic damages
Low
Agent available and
easy to handle by
professionals and
Medium
Agent available and easy to
handle by professionals and
labs and rapidly spread or
Severe
Agent available and
easy to handle by
individuals and rapidly
8.33
handle or no
spread
labs but low spread or
low economic
damages
high economic damages spread and great
economic damages
IMPACT ON TRADE - 4 criteria 0 1 2 3 4
Impact on international trade due to
existing regulations
None
No restriction
or only at
animal level
Minor
Only at herd level
Moderate
At zone level and/or a
list of commodities,
no loss of official
status
Significant
Zone standstill, loss of
official status, short recovery
period
Serious
Possible nationwide
ban standstill with or
without list, official
atatus difficult to
recover
6.25
Impact on Economic trade due to
existing regulations
None
No restriction
or only at
animal level
Minor
Only at herd level
Moderate
At zone level and/or
list of commodities
Significant
At zone level and/or no list of
commodities
Serious
Nationwide
ban/standstill with or
without list
6.25
Potential for zoning High
Zoning
possible at
farm level
Moderate
Zoning possible 1 to 10 kms
Low
Zoning possible but
more than 10 kms
Very low
Zoning using wider
administrative boundaries
None
Only compartments
6.25
Impact on security of food supply Extremely
limited,
anecdotal
Low value
Only in some remote areas
Moderate
Some remote areas
may be temporarily
out of stock
High
Some areas of the country
may be out of stock
Very High
May cause or
increase hunger
problems
6.25
CONTROL TOOLS - 3 criteria 2 1 0 -1 -2
Appropriate diagnostics Need: Yes
Availability: No
Market
Potential: Low
Need: Yes
Availability: No
Market Potential: Yes
Need: Yes
Availability: Yes (not
fully effective)
Market Potential: Low
to Medium
Need: Yes
Availability: Yes (not fully
effective)
Market Potential: Yes
Either Need: No
or Need: Yes
Availability: Yes (fully
effective)
Market Potential: Yes
16.6
6
Appropriate vaccines Need: Yes
Availability: No
Market
Potential: Low
Need: Yes
Availability: No
Market Potential: Yes
Need: Yes
Availability: Yes (not
fully effective)
Market Potential: Low
to Medium
Need: Yes
Availability: Yes (not fully
effective)
Market Potential: Yes
Either Need: No
or Need: Yes
Availability: Yes (fully
effective)
Market Potential: Yes
16.6
6
Appropriate pharmaceuticals Need: Yes
Availability: No
Market
Potential: Low
Need: Yes
Availability: No
Market Potential: Yes
Need: Bacteria - Yes
Need: Virus -
Desirable
Availability: Bacteria -
Yes (not fully
effective)
Availability: Virus - No
Market Potential: Low
to Medium
Need: Yes
Availability: Yes (not fully
effective)
Market Potential: Yes
Either Need: No
or Need: Yes
Availability: Yes (fully
effective)
Market Potential: Yes
16.6
6
TOTAL
TITLE: _______________________________________________________________________________________________________________
RATIONALE
RAT
CONTROL PROGRAM GOALS/ IMPACT
OUTCOME EXPECTED OUTPUT/ PRODUCT BREAKDOWN
STRUCTURE
CORRESPONDING ACTIVITIES/ WORK BREAKDOWN
STRUCTURE
Risk Matrix
Risk Impact Probability Mitigation
1.
2.
3.
4.
5.
OUTPUTS / ACTIVITIES YEAR 1 YEAR 2
1 2 3 4 5 6 7 8 910
11
12 1 2 3 4 5 6 7 8 9
10
11
12