E UROPEAN CURRICULUM VITAE · 2020. 12. 11. · Page 1 - Curriculum vitae of Giorgio Iervasi...

Curriculum vitae of Giorgio Iervasi [email protected]

E U R O P E A N

C U R R I C U L U M V I T A E

PERSONALINFORMATION

Name GIORGIOIERVASI

Address BORGOSANIACOPO,175LIVORNO

Telephone +390503152017

Fax +390503152651E-mail [email protected];[email protected]

Nationality ITALIANDateofbirth LIVORNO,30/05/1954

WORKINGEXPERIENCE

•Dates 2019-present

•Nameandaddressofemployer NationalResearchCouncil,InstituteofClinicalPhysiology–Pisa,Italy•Typeofbusinessorsector ManagementofrelationshipsbetweenCNRandlocalandregionalandpublicandprivateInstitutions

•Occupationorpositionheld PresidentofCNRResearchCampusofPisa•Mainactivitiesandresponsibilities CoordinationsofactivitiesofCNRInstitutesofPisa


•Nameandaddressofemployer NationalResearchCouncil,InstituteofClinicalPhysiology–Pisa,Italy•Typeofbusinessorsector ScientificResearch•Occupationorpositionheld Director,InstituteofClinicalPhysiology,NationalCouncilResearch(C.N.R.)

•Mainactivitiesandresponsibilities ResponsibleforalltheresearchactivitiesoftheInstituteofClinicalPhysiology-CNR


•Nameandaddressofemployer ScuolaSuperioreSant’AnnaPisa,Italy•Typeofbusinessorsector TranslationalMedicine•Occupationorpositionheld MemberofFacultyofTranslationalMedicinePhD

•Mainactivitiesandresponsibilities TeachingactivitiesinCardiovascularEndocrineTranslationalMedicine

•Dates 2014•Nameandaddressofemployer “SummerSchool”UniversityofPisa,Pisa,Italy

•Typeofbusinessorsector CardiovascularPathophysiology•Occupationorpositionheld Professor

•Mainactivitiesandresponsibilities TeachingactivitiesinCardiovascularEndocrinologyPathophysiology

•Dates 2012-2014•Nameandaddressofemployer CNR-TuscanyRegionG.MonasterioFoundation,Pisa,Italy

•Typeofbusinessorsector CardiovascularEndocrinologyandMetabolism•Occupationorpositionheld ScientificCoordinatorofCNR-TuscanyRegionG.MonasterioFoundation

•Mainactivitiesandresponsibilities Coordinatorofallscientificactivities


•Dates 2012-2014•Nameandaddressofemployer “ScientificAssociate”oftheEuropeanfoundedProjectFP7-ICT-2011-8"BioASQ”Achallengeonlarge-

scalebiomedicalsemanticindexingandquestionanswering•Typeofbusinessorsector ScientificResearch

•Occupationorpositionheld “ScientificAssociate”•Mainactivitiesandresponsibilities ParticipationtothedevelopmentofanewBiomedicalWeb-basedplatform


•Nameandaddressofemployer NationalResearchCouncil,InstituteofClinicalPhysiology–Pisa,Italy./TuscanyRegionGMonasterioFoundation-Pisa,Italy

•Typeofbusinessorsector Thyroiddysfunctionandcardiovascularrisk•Occupationorpositionheld MemberoftheSteeringCommitteeof“ThyroidStudiesCollaborationGroup”

•Mainactivitiesandresponsibilities The international scientific association includes theworldwide recognized experts on relationshipsbetweenthyroiddysfunctionandcardiovascularrisk

•Dates 2011-2013

•Nameandaddressofemployer NationalResearchCouncil,InstituteofClinicalPhysiology–Pisa,Italy/TuscanyRegionGMonasterioFoundation-Pisa,Italy

•Typeofbusinessorsector CardiovascularEndocrinologyandMetabolismClinical•Occupationorpositionheld Head of Cardiovascular Endocrinology and Metabolism Clinical & Experimental Department

C.N.R./TuscanyRegionGMonasterioFoundation•Mainactivitiesandresponsibilities Responsible for the clinical and scientific activities of Endocrinology and Metabolism Clinical &

ExperimentalDepartmentC.N.R./TuscanyRegionGMonasterioFoundation

•Dates 2011-present•Nameandaddressofemployer MinistryofHealthandNationalResearchCouncil,InstituteofClinicalPhysiology–Pisa,Italy

•Typeofbusinessorsector ScientificResearch•Occupationorpositionheld Member

•Mainactivitiesandresponsibilities Program Committee Member of the ‘Procollo Intesa’ between the Ministry of Health and CNR:integrationoftheHealthMinistryandCNRinitiatives

•Dates 2009-2014

•Nameandaddressofemployer ScuolaSuperioreS.AnnaPisa,Italy•Typeofbusinessorsector CardiovascularEndocrinologyandMetabolism

•Occupationorpositionheld InvitedProfessorattheScuolaSuperioreS.Anna•Mainactivitiesandresponsibilities TeachingactivitiesinCardiovascularEndocrinologyandMetabolism

•Dates 2007-2013

•Nameandaddressofemployer NationalResearchCouncil,InstituteofClinicalPhysiology–Pisa,Italy.•Typeofbusinessorsector CardiovascularEndocrinologyandMetabolism•Occupationorpositionheld ResearchDirector,C.N.R.InstituteofClinicalPhysiology

•Mainactivitiesandresponsibilities Coordinatorofresearchactivities

•Dates 2006•Nameandaddressofemployer “Higher Education Commission International Center for Chemical and Biological Sciences ” (HEJ),

ResearchInstituteofChemistry,Karachi,Pakistan•Typeofbusinessorsector ChemicalandBiologicalSciences•Occupationorpositionheld InvitedProfessor

•Mainactivitiesandresponsibilities 6“On–lineLectures”(LecturesthroughVideoConferencing).

•Dates 2004•Nameandaddressofemployer NationalResearchCouncil,InstituteofClinicalPhysiology–Pisa,Italy

•Typeofbusinessorsector Endocrinology•Occupationorpositionheld Invitedmemberto“TreatmentofHypothyroidism:ALookAhead”CytomelAdvisoryBoardMeeting-

WashingtonDC–USA(Othermembers:Dr.I.Kein,NewYork,Dr.J.R.Garber,Boston,Dr.D.Ascheim,New York, Dr. T. Bigos, Scarborough, Dr. P.W. Clyde, Virginia Beach, Dr. S. Danzi, Manhasset, Dr. J.Klemperer,Bangor,Dr.R.Levine,Nashua,Dr.S.J.Mendel,Ardmore)

•Mainactivitiesandresponsibilities Expertscientificconsultant

•Dates 2003•Nameandaddressofemployer AmericanAssociationforEradicationofHeartAttack–VulnerablePlaque(AEHA)

•Occupationorpositionheld InvitedmemberoftheScientificAdvisoryBoard•Mainactivitiesandresponsibilities Editorialactivities


•Dates 2001-2006•Nameandaddressofemployer NationalResearchCouncil,InstituteofClinicalPhysiology–Pisa,Italy

•Typeofbusinessorsector CardiovascularEndocrinologyandMetabolism•Occupationorpositionheld SeniorResearcherC.N.R.,InstituteofClinicalPhysiology

•Mainactivitiesandresponsibilities Responsibleofresearchprojects

•Dates 1998-2010•Nameandaddressofemployer NationalResearchCouncil,InstituteofClinicalPhysiology–Pisa,Italy

•Typeofbusinessorsector CardiovascularEndocrinologyandMetabolism•Occupationorpositionheld Chief of the Cardiovascular Endocrine Research and Clinical Unit of the C.N.R. Institute of Clinical

Physiology/G.MonasterioFoundation•Mainactivitiesandresponsibilities Clinicalandresearchactivities

•Dates 1998-2004

•Nameandaddressofemployer ScuolaSuperioreS.AnnaPisa,Italy,incollaborationwithIFC-CNRandtheInternationalHeartSchool,BergamoItaly

•Typeofbusinessorsector “InternationalMasterinCardiology,Cardio-surgeryandcorrelatedAnesthesia”•Occupationorpositionheld Professor

•Mainactivitiesandresponsibilities Professorwithintheframeofthevariouseditionsofthe“InternationalMasterinCardiology,Cardio-surgeryandcorrelatedAnesthesia”

•Dates 1997-2000

•Nameandaddressofemployer MinistryofEducation,UniversitiesandResearch(Italy)•Typeofbusinessorsector CardiovascularEndocrinologyandMetabolism

•Occupationorpositionheld Responsible•Mainactivitiesandresponsibilities ResponsibleofWorkPackage2,CCCN1"Biologicalandmolecularbasesofcongenitalneonatalheart

diseases,neuroendocrinefactorsandcardiomyocytes:analysis, identificationandcharacterizationofpossiblecorrelationsbetweencongenitalheartdiseasesandsystemicandintracellularmetabolismofthyroidhormones"oftheNationalProject"NeonatalcriticalcongenitalHeartDisease."

•Dates 1991-1997

•Nameandaddressofemployer UniversityofPisa,Italy•Typeofbusinessorsector InternalMedicineandNuclearMedicine•Occupationorpositionheld Invited Professor Post graduate Schools for Doctors (Internal Medicine and Nuclear Medicine

Specialties)•Mainactivitiesandresponsibilities TeachingactivitiesinInternalMedicineandNuclearMedicine

•Dates 1991-1994

•Nameandaddressofemployer UniversityofPisa,Italy•Typeofbusinessorsector "Elements of Radiobiology, Radiation Dosimetry and Applied Biology of non-ionized andMetabolic

StudieswithRadioactiveTracersinNuclearMedicine"•Occupationorpositionheld InvitedadjunctProfessor

•Mainactivitiesandresponsibilities Teaching activities in Elements of Radiobiology, Radiation Dosimetry and Applied Biology of non-ionizedandMetabolicStudieswithRadioactiveTracersinNuclearMedicine

•Dates 1991-1992

•Nameandaddressofemployer UniversityofPisa,Italy•Typeofbusinessorsector “GastroenterologyandDigestiveEndoscopy”

•Occupationorpositionheld InvitedadjunctProfessor•Mainactivitiesandresponsibilities TeachingactivitiesinNuclearMedicineGastroenterology

•Dates 1990

•Nameandaddressofemployer NationalResearchCouncil,InstituteofClinicalPhysiology–Pisa,Italy•Typeofbusinessorsector CardiovascularEndocrinologyandMetabolism

•Occupationorpositionheld ResearcherC.N.R.,InstituteofClinicalPhysiology•Mainactivitiesandresponsibilities Researchactivities

EDUCATIONANDTRAINING

•Dates•Nameandtypeoforganisationprovidingeducationandtraining•Principalsubjects/occupational

skillscovered

June-December2015MIPPolitecnicodiMilanoGraduateSchoolofBusinessAdvancedCourse“ManagementpathforthedirectorsofscientificstructuresoftheCNR”-Directorofthecourse:ProfMArbaboldi


•Dates 1986

•Nameandtypeoforganisationprovidingeducationandtraining

UniversityofPisa,Pisa,Italy

•Principalsubjects/occupationalskillscovered

NuclearMedicine

•Levelinnationalclassification Specialization

•Dates 1983•Nameandtypeoforganisationprovidingeducationandtraining



InternalMedicine

•Levelinnationalclassification Specialization

•Dates 1978•Nameandtypeoforganisationprovidingeducationandtraining



Medicine

•Titleofqualificationawarded GraduatedegreeinMedicine•Levelinnationalclassification MD

MOTHERTONGUE

Italian

OTHERLANGUAGES English•Reading Intermediate•Writing Intermediate•Speaking Intermediate

OTHERLANGUAGES French

•Reading Basic•Writing Basic•Speaking Basic

• OTHERRELEVANT

INFORMATIONABOUTTHESCIENTIFICAND

PROFESSIONALCAREER

-MemberoftheSelectFacultytosubmitnominationfor2016RossPrizeMolecularMedicine.-PresidentofCNRExpertPanel(BiomedicalArea)fortheevaluationofresearchprojectsoftheItalianMinistryofEconomicDevelopment(MISE)-CNRCoordinatorofthe“CasaItalia”projectforthe“Exposuretoriskofpeopleandthings”.ManagementPathforDirectorsofScintificResearchDepartmentsofCNRNationalResearchCouncil–DirectorofCourseProf.MichelaArnaboldi–PolitecnicodiMilanoGraduateSchoolofBusiness–July/December2015InternationalexperienceEducation1998 Post-doctoral Course at the Albert Einstein College of Medicine and Montefiore Medical Center" New York, U.S.A. 1996 Holder of CNR extraordinary assignment, Central Scientific Activity Department, for a three-month study stay at the NIH (Bethesda, USA) Member:ManagingEditor:InternationalJournalofEndocrinologyEditorialBoard:FrontiersPhysiologyEditorialBoard:FrontiersEndocrinologyEditorialBoard:WorldJournalofDiabetesEditorialBoard:JournalofGeriatricCardiologyEditorialBoard:ISRNCardiology2009 EditoroftheBook“ThyroidandHeartFailureFromPathophysiologytoClinics”,SpringerVerlagPublisher.Reviewerfor:CirculationNatureReviewsEndocrinologyandMetabolismJournalofMolecularandCellularEndocrinology


JournalofClinicalEndocrinologyandMetabolismEndocrinologyAmericanJournalofPhysiologyEuropeanJournalofEndocrinologyCriticalCareClinicalEndocrinologyExperimentalPhysiologyAmericanJournalofCardiologyJournalofEndocrinologyEuropeanJournalofClinicalInvestigationThyroidMolecularandCellularEndocrinologyEndocrineEuropeanJournalofRadiologyRegulatoryPeptidesCriticalCareMedicineHormoneMetabolicResearchIntensiveCareMedicineBiochemistryandCellBiologyICRSCardiologyMedicalScienceMonitoring

Maininternationalinvitedlectures(last10years):”XVI EUROPEAN CONGRESS OF ENDOCRINOLOGY; EUROPEAN SOCIETY OF ENDOCRINOLOGY” 3-7May2014,WROCLAWPoland;”Thyroiddysfunctionincriticallyillpatients:totreatornottotreat?“XV LATINAMERICANTHYROID CONGRESS”, 21-23March 2013, FLORIANOPOLIS, Brazil; “ThyroidHormonereplacementtherapyandheartfailure:whenandhow””XV LATIN AMERICAN THYROID CONGRESS”, 21-23 March 2013, FLORIANOPOLIS, Brazil;“ProangiogeneticactionofTSHthroughitsmembranereceptor””XV LATINAMERICANTHYROID CONGRESS”, 21-23March 2013, FLORIANOPOLIS, Brazil; “ThyroidHormoneandtheCardiovascularSystem:fromBasicConceptstoClinicalApplications”“CHINA HEART CONGRESS”, Beijing, China, 11-14 August 2011; ”Thyroid Hormone Treatment inCardiacDiseases:MoreLightthanShadow”“14THINTERNATIONALTHYROIDCONGRESS”,Paris,11-16September2010;“ThelowT3syndromeincardiacpatientsanditstreatmentwithT3”“INTERNATIONAL CARDIOLOGY CONGRESS: TRACK 1-15 2009: HEART FAILURE”, China; “Thyroidfunctionandheartfailure”

Honors2003Awardas“FeaturedArticleoftheMonth"bytheAEHAInternationalSociety(AssociationfortheEradicationofHeartAttack)fortheArticle:"Low-T3Syndrome:astrongprognosticpredictorofdeathinpatientswithheartdisease"(Circulation2003;107:708-713)Maininternationalresearchsupport(last7years)-PartneroftheEuropeanCommunity-fundedSeventhFrameworkProgrammeThemeProjectCIP-ICT-PSP-2012, Title: “OpenScienceLink- Open Semantically-enabled, Social-aware Access to ScientificData”.Mainongoingnationalresearchsupport(last7years)-Responsible of three-year Italian Grant: “Study of the molecular, biochemical and metabolicmechanismsinvolvedinthecardioprotectiveeffectofT3”.


PUBBLICATIONS1. CarpiA.,IervasiG.,NicoliniA.,DelCorsoL.,LevantiC.,ZucchelliG.C.,BianchiR.Serumthyroidhormoneconcentrationsandrecovery

ofTSHsecretionafterexcisionofautonomouslyfunctioningthyroidnodulesMetabolism1982;31(5):417-4202. Nicolini A., Immacolato M., Lazzerini G., Iervasi G., Carpi A. Effetti della associazione metimazomo-dibromotirosina sui livelli

circolantidegliormonitiroideiedelTSHinPazientiipertiroideiFarmaci1983;4:3-83. CarpiA.,IervasiG.,NicoliniA.,BianchiR.ClinicaluseoffreeserumthyroidhormonesassaysRAYSSciences1984;9(1):131-1424. Bianchi R., Molea N., Cazzuola F., Fusani L., Iervasi G., Bertelli P., FerdeghiniM.,Mariani G. Separazione HPLC delle iodotironine

siericheperstudisulmetabolismoperifericodegliormonitiroideiinvivo.LigandQuaterly1986:5(4):57-685. BianchiR.,PiloA.,IervasiG.,VitekF.,FerdeghiniM.,CazzuolaF.,MoleaN.MulticompartmentalvsnoncompartmentalanalysisofT4

andT3kineticsinnormalsandhypothyroidpatients.NuklearmedizinF.K.SchattauerVerlag,1987,332-3346. Bianchi R., Iervasi G., Pilo A., Vitek F., Ferdeghini M., Cazzuola F., Giraudi G.F. Role of serum carrier proteins in the peripheral

metabolismandtissuedistributionofthyroidhormonesinfamilialdysalbuminemichyperthyroxinemiaandcongenitalelevationofthyroxine-bindingglobulinJClinInvest1987;80:522-534

7. Carpi A., Nicolini A., Iervasi G., Toscano S., Giannessi., Luti R. Evaluation of a new pharmacological preparation containing L-

Thyroxineinsolution:comparisonwithL-ThyroxineandTriiodotironinetabletsClinicalTrialsJournal1988;25(3):172-1808. PiloA., IervasiG.,VitekF.,FerdeghiniM.,CazzuolaF.,BianchiR .Thyroidalandperipheralproductionof3,5,3’-triiodothyronine in

humansbymulticompartmentalanalysisAmJPhysiol1990;258:E715-E7269. PiloA.,ZucchelliG.C.,MalvanoR.,ClericoA.,IervasiG.SignoriniC.Interassayvariabilityofimmunometricmethodsforthyrotropinin

anexternalqualityassessmentsurvey:evidencethat functionalsensitivity isnotalwaysadequate forclinicaldecisionsClinChem1992;38:1345-9

10. Bianchi R., Iervasi G., Matteucci F., Turchi S., Cazzuola F., Bellina R.C., Boni G., Molea N., Ferdeghini M., Toni M.G., Mariani G.

Chromatographic identification in serum of endogenously radioiodinated thyroid hormones after iodine-131 whole bodyscintigraphyinthefollow-upofpatientswithdifferentiatedthyroidcarcinomaJNuclMed1993;34:2032-37

11. Iervasi G. Clerico A., Berti S., Pilo A., Vitek F., Biagini A., BarattoM.T., Bianchi R., Donato L. ANP kinetics in normalmen: in vivo

measurementbyatracermethodandcorrelationwithsodiumintake.AmJPhysiol1993;264:F480-912. PiloA.,IervasiG.,VitekF.,TurchiS.,BianchiR.DisposalanddistributionofrT3inhumans:anewdouble-tracerkineticstudyAmJ

Physiol1993;264(2pt1):E239-4913. ClericoA.,IasconeM.R.,ManfrediC.andIervasiG.Theroleofnuclearmedicineintheassessmentoftheendocrinefunctionofthe

heartJNuclBiolMed1994;38:37-4614. IervasiG.,ClericoA.,PiloA.,BertiS.,VitekF.,BiaginiA.,BianchiR.,DonatoL.Kineticstudyofatrialnatriureticpeptideinpatients

with idiopathic dilated cardiomyopathy: evidence for resistance to biologic effects of the hormone even in patients with mildmyocardialinvolvementJCardiovascPharmacol1994;24:626-37

15. BiaginiA.,IervasiG.,ClericoA.,BertiS.,PiloA.,VitekF.,BoniniR.,BianchiR.,DonatoL.Peripheralthyroidhormonemetabolismin

patientswithcomplexventriculararrhythmiasAmJCardiol1995;75:630-316. ClericoA.,IervasiG.,BertiS.,PiloA.,VitekF.,SalvadoriS.,MarastoniM.,ManfrediC.,DelChiccaM.G.,IasconeM.R.,BiaginiA.Invivo

measurementofANPoverallturnoverandidentificationotitsmainmetabolicpathwaysundersteadystateconditionsinhumansJEndocrinolInvest1995;18:194-204

17. ClericoA.,IervasiG.,IasconeM.R.,ManfrediC.,SabatinoL.,BertelliA.,BertelliA.A.E.Evaluationoftheendocrinefunctionoftheheart

inhumans:Proposalforanintegratedapproachfortheassessmentofproduction,secretion,distributionanddegradationofAtrialNatriureticFactorandRelatedPeptidesIntJClinPharmacol1995;15:65-86

18. ClericoA.,IervasiG.,ManfrediC.,SalvadoriS.,MarastoniM.,TurchiS.,DelChiccaM.G.,GiannessiD.,DelRYS.,AndreassiM.G.,Biagini

A.,DonatoL.Preparationofmono-radio-iodinatedtracersforstudyingtheinvivometabolismofatrialnatriureticpeptideinhumans.EurJNuclMed1995;22:997-1004

19. ClericoA.,IervasiG.AlterationsinmetabolicclearanceofANPinheartfailure:howdoesitrelatetotheresitancetoANP?JCardFail

1995;1(4):323-32820. IervasiG.,ClericoA.,BertiS.,PiloA.,BiaginiA.,BianchiR.,DonatoL.AlteredtissuedegradationanddistributionofAtrialNatriuretic

Peptide in patients with idiopathic dilated cardiomyopathy and its relationshipwith clinical severity of the disease and sodiumhandlingCirculation1995;91:2018-27

21. Manfredi C., Clerico A., Iervasi G., Turchi S., Cazzuola F., Berti S., Sabatino L., Biagini A. Measurement of serum amiodarone and

desethylamiodaronebyHPLC:itsusefulnessinthefollow-upofarrhythmicpatientstreatedwithamiodaroneIntJClinPharmacol1995;15:87-93

22. MurziB., IervasiG.,MasiniS.,MoschettiG.,VaniniV.,ZucchelliG.C.,BiaginiA.Thyroidhormoneshomeostasisinpediatricpatients

duringandaftercardiopulmonaryby-passAnnThoracSurg1995;59:481-485


23. ClericoA.,IervasiG.,IasconeM.R.,ManfrediC.,SabatinoL.,BiaginiA.Resistancetobiologicaleffectsofatrialnatriureticpeptidein

heartfailure.InternalMed1995;3:57-6424. Del Ry S., AndreassiM.G., Lazzerini G., Iervasi G., Clerico A., Biagini A., Giannessi D. Determination of endothelin binding sites in

bovineatriumandventriclemembranes:amodelforbindingstudiesinhumancardiactissueIntJTissReac1995;XVII(3):117-12425. IervasiG.,ClericoA.,BertiS.,PiloA.,ManfrediC.,SabatinoL.,IasconeM.R.,PalmieriC.,BiaginiA.,DonatoL.Alteredperipheralthyroid

hormonemetabolisminpatientswithcomplexventriculararrhythmiasandnormalserumconcentrationsofthyroidhormonesandTSHThyroidologyClinExp1995;7:43-8

26. Iervasi G., Clerico A., Pilo A., Berti S., Vitek F., Biagini A., Bianchi R., Donato L. Normalization of peripheral thyroid hormone

metabolism induced by successful chronic amiodarone treatment in patients with ventricular arrhythmias Eur J Clin Invest1996;26:382-90

27. Berti S., Palmieri C., Ravani M., Bonini R., Iascone M.R., Clerico A., Manfredi C., Iervasi G., Biagini A. Acute enoximone effect on

systemicandrenalhemodynamicsinpatientswithheartfailureCardiovascDrugTher1996;10:81-8728. Clerico A., Iervasi G., Del Chicca M.G., Maffei S., Berti S., Sabatino L., Turchi S., Cazzuola F., Manfredi C., Biagini A. Analytical

performanceandclinicalusefulnessofacommerciallyavailable IRMAkit formeasuringatrialnatriureticpeptide inpatientswithheartfailureClinChem1996;42:1627-33

29. IervasiG.,ClericoA.,BoniniR.,ManfrediC.,RavaniM.,ForiniF.,PalmieriC.,TurchiS.,CazzuolaF.,MusettiM.,BiaginiA.Acuteeffects

of intravenous amiodarone administration on thyroid function in arrhythmic patients: preliminary results Thyroidol Clin Exp1996;8:21-27

30. ClericoA., Iervasi G., Forini F. Importance of circulatorymodels in turnover studies of hormones rapidly cleared from the blood

stream:theexampleofatrialnatriureticpeptideInternalMed1996;4:53-5631. Carpi A., Ferrari E., Sagripanti A., Nicolini A., Iervasi G., De Gaudio C., Romani R., Di Coscio G. Aspiration needle biopsy refines

preoperativediagnosisofthyroidnodulesdefinesaspirationasmicrofollicularnoduleBiomedPharmacother1996;50(8):325-832. IervasiG.,ClericoA.,BoniniR.,ManfrediC.,BertiS.,RavaniM.,PalmieriC.,CarpiA.,BiaginiA.,ChopraI.J.Acuteeffectsofamiodarone

administrationonthyroidfunctioninpatientswithcardiacarrhythmiaJClinEndocrinolMetab1997;82:275-8033. IervasiG.,ClericoA.,PiloA.,VitekF.,BertiS.,PalmieriC.,RavaniM.,SabatinoL.,ManfrediC.,DelChiccaM.G.,BiaginiA.,DonatoL.

EvidencethatatrialnatriureticpeptidetissueextractionisnotchangedbylargeincreasesofitsplasmalevelsinducedbypacinginhumansJClinEndocrinolMetab1997;82:884-888

34. IervasiG.,ClericoA.,ManfrediC.,SabatinoL.,BiaginiA.,ChopraI.J.Acuteeffectsofintravenousamiodaroneonsulphatemetabolites

ofthyroidhormonesinarrhythmicpatientsClinEndocrinol1997;47(6):699-70535. PiloA., Iervasi G., ClericoA., Vitek F., Berti S., Palmieri A., Biagini A., Donato L. Circulatorymodel inmetabolic studies of rapidly

renewedhormones:applicationtoANPkineticsAmJPhysiol(sez.“ModelinginPhysiology”)1998;274(3):E560-E57236. VitekF.,PiloA.,PichJ.,IervasiG.,ZitkoM.,ClericoA.Applicabilityofacirculatorymodelfordeterminingtheparametersofkineticsof

endogenouslyproducedcompoundsSbornLek1998;99(4):539-54737. IervasiG.,ClericoA.,BoniniR.,NannipieriM.,ManfrediC., SabatinoL.,BiaginiA.,DonatoL.Effectofantiarrhythmic therapywith

intravenous loading dose of amiodarone: evidence for an altered response in diabetic patients Int J Clin Pharmacol Res1998;18(3):109-20

38. IervasiG.,ClericoA.,PiloA.,SabatinoL.,ManfrediC.,ForiniF.,DelChiccaM.G.,PalmieriC.,RavaniM.,DonatoL.Atrialnatriuretic

peptideisnotdegradedbythelungsinhumansJClinEndocrinolMetab1998;83(8):2898-90639. Maffei S., ClericoA., IervasiG.,NannipieriM.,DelRy S., GiannessiD.,DonatoL. Circulating levels of cardiacnatriuretichormones

measuredinwomenduringmenstrualcycleJEndocrinolInvest1999;22(1):1-540. ClericoA., IervasiG.,Del ChiccaM.G., EmdinM.,Maffei S.,NannipieriM., SabatinoL., Forini F.,ManfrediC.,DonatoL., Circulating

levelsofcardiacnatriureticpeptides(ANPandBNP)measuredbyhighlysensitiveandspecificimmunoradiometricassaysinnormalsubjectsandinpatientswithdifferentdegreesofheartfailureJEndocrinolInvest1998;21(3):170-9

41. Iervasi G., Manfredi C., Scarlattini M., Emdin M., Caratterizzazione e follow-up della funzione tiroidea nel paziente trattato con

amiodaroneCardiolExtraosp1998;4:366-36942. ClericoA.,IervasiG.,DelRyS.,GiannessiD.,Immunoassaymethodsforthemeasurementofnatriureticcardiachormones-ANP,BNP,

andrelatedpeptides-inhumansJClinicalLigandAssay1999;22:194-20443. ClericoA.,IervasiG.,MarianiG.,Pathophysiologyrelevanceofmeasuringtheplasmalevelsofcardiacnatriureticpeptidehormones

inhumansHormMetabRes1999;31(9):487-9844. ClericoA.,IervasiG.,PiloA.Turnoverstudiesoncardiacnatriureticpeptides:methodological,pathophysiologicalandtherapeutical

considerationsCurrentDrugMetabolism2000;1:85-105


45. EmdinM.,PrataliL.andIervasiG.AbolishedvagaltoneassociatedwiththyrotoxicosistriggersprinzmetalvariantparoxysmalatrialfibrillationAnnInternMed2000;132(8):679

46. SabatinoL., IervasiG.,FerrazziP.,FrancesconiD.,ChopraI.J.Astudyof iodothyronine5’-monodeiodinaseactivities innormaland

pathologicaltissuesinmanandtheircomparisonwithactivitiesinrattissuesLifeSciences2000;68:191-20247. Colzani R.M., Emdin M., Conforti F., Passino C., Scarlattini M. and Iervasi G. Hypertyroidism is associated with lenghtening of

ventricularrepolarizationClinEndocrinol2001;55(1):27-3248. Sabatino L., Chopra I.J., Tanavoli S., Iacconi P. and Iervasi G. A radioimmunoassay for type I iodothironine 5’-monodeiodinase in

humantissuesThyroid2001;11(8):733-73949. Forini F., Paolicchi A., Pizzorusso T., Ratto G.M., Saviozzi M., Vanini V and Iervasi G. 3,5,3’-thiiodothyronine deprivation affects

phenotypeandintracellular(Ca2+)IofhumancardiomyocytesincultureCardiovascRes2001;51(2):322-3050. Fommei E., Iervasi G. The role of thyroid hormone in blood pression homeostasis: evidence from short-term hypothyroidism in

humans.JClinEndocrinolMetab2002;87:1996-200051. SabatinoL.,CerilloA.G.,RipoliA.,PiloA.,GlauberM.,IervasiG.IsthelowT3stateacrucialfactordeterminigtheoutcomeofcoronary

arterybypasspatients?Evidencefromaclinicalpilotstudy.JEndocrinology2002;175:577-8652. Iervasi G., PingitoreA., Landi P., RacitiM., Ripoli A., ScarlattiniM., L’AbbateA., Donato L. Low-T3 syndrome: a strong prognostic

predictorofdeathinpatientswithheartdisease.Circulation2003;107:708-71353. IervasiG.,PingitoreA.,LandiP.,RacitiM.,RipoliA.,ScarlattiniM.,L’AbbateA.,DonatoL.Lowtriiodothyronineandcardiovascular

disease.Circulation2003;108(4):authorreplye29-3054. NicoliniG.,BalzanS.,ColzaniR.,ScarlattiniM.,TaddeiM.C.,andIervasiG.ErythrocyteNa+/K+-ATPaseisincreasedinsubjectswith

subclinicalhypothyroidism.ClinicalEndocrinology2004;60:705-71055. Iervasi A., Iervasi G., Bottoni A., Boni G., Annichiarico C., Di Cecco P., and Zucchelli GC.Diagnostic performance of a new highly

sensitivethyroglobulinimmunoassay.JournalofEndocrinology2004;182:287-29456. ForiniF.,NicoliniG.,BalzanS.,RattoGM.,MurziB.,VaniniV., IervasiG.Amiodaroneinhibitsthe3,5,3’-triiodothyronine-dependent

increase of sodium potassium adenosine triphosphatase activity and concentration in human atrial myocardial tissue. Thyroid2004;14(7):491-497

57. ScosciaE.,BaglioniS.,EslamiA.,IervasiG.,MontiS.,TodiscoT.Lowtriiodothyronine(T3)state:apredictorofoutcomeinrespiratory

failure?Resultsofaclinicalpilotstudy.EuropeanJournalofEndocrinology2004;151(5):557-6058. Gasbarri A., Marchetti C., Iervasi G., Bottoni A., Nicolini A., Bartolazzi A., Carpi A. From the bench to the bedside. Galectin-3

immunodetectionforimprovingthepreoperativediagnosisofthefollicularthyroidnodules.BiomedPharmacother2004;25:356-59

59. ColantuoniA.,MarchiafavaPL.,LapiD.,ForiniFS.,IervasiG.Theeffectsoftetraiodothyronineandtriiodothyronineonhamstercheek

pouchmicrocirculation.AmJPhysiolHeartCircPhysiol2005;288:H1931-193660. PingitoreA.,LandiP.,TaddeiMC.,RipoliA.,L’AbbateA., IervasiG.Triiodothyronine levels forriskstratificationofpatientswith

chronicheartfailure.AmericanJournalofMedicine2005;118:2:132-3661. RipoliA.,PingitoreA.,FavilliB.,BottoniA.,TurchiS.,OsmanN.,DeMarchiD.,LombardiM.,L’AbbateA.,IervasiG.Doessubclinical

hypothyroidismaffectcardiacpumpperformance?EvidencefromaMagneticResonanceImagingstudy.JACC2005;45:439-4562. SabatinoL.,ColantuoniA.,IervasiG.IstheVascularSystemaMainTargetforThyroidHormones?FromMolecularandBiochemical

FindingstoClinicalPerspectives.CurrentVascularPharmacology2005;3:133-14563. PingitoreA.,IervasiG.Thyroid(dys)functioninheartfailure:isitapotentialtargetformedicaltreatment?Vascularhealthandrisk

management2005;1(2):97-10064. PingitoreA.,IervasiG.Funzionetiroideaescompensocardiaco:dallenuoveevidenzeclinicheallepossibiliimplicazioniterapeutiche.

RecentiProgressiinMedicina2005;96(11):535-54165. CarpiA.,NaccaratoAG.,IervasiG.,NicoliniA.,BevilacquaG.,ViacavaP.,CollecchiP.,LavraL.,MarchettiC.,SciacchitanoS.,Bartolazzi

A.Largeneedleaspirationbiopsyandgalectin-3determinationinselectedthyroidnoduleswithindeterminatedFNA-cytology.BrJCancer2006;95(2):204-9

66. IervasiA.,IervasiG.,CarpiA.,ZucchelliGC.Serumthyroglobulinmeasurement:clinicalbackgroundandmainmethodologicalaspects

withclinicalimpact.Biomedicine&Pharmacotheraphy2006;60:414-42467. PingitoreA., Iervasi G., BarisonA., Prontera C., Pratali L., EmdinM., GiannessiD., NegliaD. Early activation of an altered thyroid

hormoneprofile inasymptomaticormildlysymptomatic idiopathic leftventricular dysfunction. JournalofCardiacFailure2006;12(7):520-526

68. Franchi D., Iervasi G., Cini D., Benassi A., Cristofani R. Modello computerizzato per la Valutazione Integrata del Rischio

Cardiovascolare(VIRC):fattorinotiedemergenti.RivistaItalianad’Igiene2006;66(1-2):7-25


69. IervasiG.Thyroidandheartfailure.Thyroidology2006;17:1-970. CarpiA.,NicoliniA.,MarchettiC., IervasiG.,AntonelliA.,CarpiF.Percutaneous largeneedleaspirationbiopsyofpalpable thyroid

nodules:technicalanddiagnosticperformance.Histopathology2007;51:249-25771. IervasiG.,MolinaroS.,LandiP.,TaddeiM.C.,GalliE.,MarianiF.,L’AbbateA.,PingitoreA.Associationbetweenincreasedmortalityand

mildthyroiddysfunctionincardiacpatients.ArchInternMed2007;167(14):1526-153272. IervasiA.,IervasiG.,FerdeghiniM.,SolimeoC.,BottoniA.,RossiL.,ColatoC.,ZucchelliG.C.ClinicalrelevanceofhighlysensitiveTg

assayinmonitoringpatientstreatedfordifferentiatedthyroidcancer.ClinicalEndocrinology2007;67(3):434-44173. SabatinoL.,GliozheniE.,MolinaroS.,BonottiA.,AzzolinaS.,PopoffG.,CarpiA.,IervasiG.ThyroidhormonereceptorandIGF1/IGFR

systems:Possiblerelationsinthehumanheart.BiomedPharmacother2007;61(8):457-62.Epub2007May22.74. Balzan S., Nicolini G., Forini F., Boni G., Del Carratore R., Nicolini A., Carpi A., Iervasi G.Presence of a functional TSH receptor on

humanerythrocytes.BiomedPharmacother2007;61(8):463-7.Epub2007May25.75. PingitoreA.,DiBellaG.,LombardiM.,IervasiG.,StrataE.,AquaroG.D.,PositanoV.,DeMarchiD.,RossiG.,L'AbbateA.,RovaiD.The

obesityparadoxandmyocardialinfarctsize.JCardiovascMed(Hagerstown).2007Sep;8(9):713-776. Pingitore A., Iervasi G. Triiodothyronine (T3) effects on cardiovascular system in patients with heart failure. Recent Patents on

CardiovascularDrugDiscovery2008;3:(1):19-27.Review.77. PingitoreA.,GalliE.,BarisonA.,IervasiA.,ScarlattiniM.,NucciD.,L'AbbateA.,MariottiR.,IervasiG.Acuteeffectsoftriiodothyronine

replacement therapy in patientswith chronic heart failure and low-t3 syndrome: a randomized, placebo-controlled study. J ClinEndocrinolMetab.2008;93(4):1351-8

78. CarpiA.,DiCoscioG.,IervasiG.,AntonelliA.,MechanickJ.,SciacchitanoS.,NicoliniA.Thyroidfineneedleaspiration:Howtoimprove

clinicians'confidenceandperformancewiththetechnique.CancerLett.2008;264(2):163-17179. IervasiG.Iltumoredifferenziatotiroideo:principididiagnosi,stadiazioneetrattamento.LigandAssay2008;13(3):191-19680. Balzan S., Frascarelli S., Nicolini G., Lubrano V., Forini F., Iervasi G., Zucchi R., Montali U. Acute infusion of recombinant human

thyrotropininLangendorff-rathearts:Roleofathyrotropinreceptor.IntJCardiol.2009Jul;27(5):259-6381. Passino C., Pingitore A., Landi P., Iervasi G. Prognostic value of combined measurement of brain natriuretic peptide and

triiodothyronineinheartfailure.JCardFail.2009Feb;15(1):35-40.Epub2008Oct4.82. GimelliA.,RossiG.,LandiP.,MarzulloP.,IervasiG.,L'AbbateA.,RovaiD.Stress/RestMyocardialPerfusionAbnormalitiesbyGated

SPECT:StilltheBestPredictorofCardiacEventsinStableIschemicHeartDisease.JNuclMed.2009Mar16.83. Balzan S, Del Carratore R, Nicolini G, Forini F, Lubrano V, Simili M, Benedetti PA, Iervasi G TSH induces co-localization of TSH

receptorandNa/K-ATPaseinhumanerythrocytes.CellBiochemFunct.2009:22;27(5):259-263.[Epubaheadofprint]84. NannipieriM.,CecchettiF.,AnselminoM.,NicoliniG.,LaMacchiaS.,CamastraS.,M.RossiM.,IervasiG.,FerranniniE.Expressionof

thyrotropin and thyroid hormone receptors in adipose tissue of subjectswithmorbid obesity and/or type 2 diabetes: effects ofweightloss.InternationalJournalofObesity2009:33(9):1001-6

85. Coceani M., Iervasi G., Pingitore A., Carpeggiani C., L’Abbate A. Thyroid hormone and coronary artery disease: from clinical

correlationstoprognosticimplications.ClinCardiol2009:32(7):380-38586. Cini A., Carpi A., Mechanick J., Cini L., Camici M., Galetta F., Giardino R., Russo M.A., Iervasi G. Thyroid hormones and the

cardiovascularsystem;pathophysiologyandinterventions.BiomedicineandPharmacotherapy2009;63:742-75387. Zucchelli G.C., Iervasi A., Ferdeghini M., Iervasi G. Serum thyroglobulin measurement in the follow-up of patients treated for

differentiatedthyroidcancer.QJNuclMedMolImaging.2009Oct;53(5):482-9.88. Galli E., Pingitore A., Iervasi G. Thyroid hormone in the pathopysiology of heart failure: clinical evidence. Heart Fail Rev.

2010;15(2):155-6989. LubranoV.,PingitoreA.,CarpiA.,IervasiG.Relationshipbetweentriiodothyronineandproinflammatorycytokinesinchronicheart

failure.BiomedicineandPharmacotherapy2010Mar;64(3):165-990. Carpi A., Rossi G., Coscio G.D., Iervasi G., Nicolini A., Carpi F., Mechanick JI., Bartolazzi A. Galectin-3 detection on large-needle

aspirationbiopsyimprovespreoperativeselectionofthyroidnodules:Aprospectivecohortstudy.AnnMed2010;42(1):70-891. CerilloA.G.,StortiS.,ClericoA., IervasiG.Thyroid functionandcardiacsurgery:whatshouldwemeasure,andwhen?AnnThorac

Surg.2010Mar;89(3):1010-1.92. Pingitore A., Iervasi G., GerdesMA. Letter by Pingitore et al regarding article, "DITPA (3,5-diiodothyropropionic acid), a thyroid

hormone analog to treat heart failure: phase II trial VeteransAffairs cooperative study". Circulation. 2010Mar16;121(10):e240;authorreplye241


93. GerdesM.A., IervasiG. Thyroid replacement therapy andheart failure. ContemporaryReviews inCardiovascularMedicine series.Circulation2010;122(4):385-393

94. RodondiN.,DenElzenWP.,BauerD.C.,CappolaA.R.,RazviS.,WalshJ.P.,AsvoldB.O.,IervasiG.,ImaizumiM.,ColletT.H.,BremnerA.,

Maisonneuve P., Sgarbi J.A., KhawK.T., VanderpumpM.P., Newman A.B., Cornuz J., Franklyn J.A.,Westendorp R.G., Vittinghoff E.,Gussekloo J., for the Thyroid Studies Collaboration. Subclinical Hypothyroidism and the Risk of Coronary Heart Disease andMortality.JAMA2010Sep22;304(12):1365-1374.

95. IervasiG.,ClericoA.Harmonizationoffreethyroidhormonetests:amissionimpossible?ClinChemMed2011;4996. FranchiD,CiniD, IervasiG.AnewWeb-basedmedical tool forassessmentandpreventionof comprehensivecardiovascular risk.

TherClinRiskManag.2011;7:59-68.Epub2011Feb17.97. PingitoreA,ChenY,GerdesAM,IervasiG.Acutemyocardialinfarctionandthyroidfunction:Newpathophysiologicalandtherapeutic

perspectives.AnnMed.2011May1398. CoceaniM,MolinaroS,ScaleseM,LandiP,CarpeggianiC,L'AbbateA,IervasiG,PingitoreA.Thyroidhormone,amiodaronetherapy,

andprognosisinleftventricularsystolicdysfunction.JEndocrinolInvest.2011;34(6):e144-14899. Giovannini S, Zucchelli GC, Iervasi G, Iervasi A, Chiesa MR, Mercuri A, Renieri A, Prontera C, Conte R, Clerico A. Multicentre

comparisonoffreethyroidhormonesimmunoassays:theImmunocheckstudy.ClinChemLabMed2011;49100. Mourouzis I , ForiniF ,PantosC , IervasiG .Thyroidhormoneandcardiacdisease : frombasic concepts to clinical application J

ThyroidRes.2011;2011:958626.Epub2011Jun19.101. BalzanS,CarpiA,EvangelistaM,NicoliniG,PollastriA,BottoniA,IervasiG.AcuteeffectofTSHonoxygenationstateandvolumeof

erythrocytesfromsubjectsthyroidectomizedfordifferentiatedthyroidcarcinoma.iomedPharmacother.2011;65(5):381-4.Epub2011Jun17.

102. ForiniF.,LionettiV.,ArdehaliH.,PucciA.,CecchettiF.,GhanefarM.,NicoliniG.,IchikawaY.,NannipieriM.,RecchiaF.A,IervasiG.Early

long-term L-T3 replacement rescues mitochondria and prevents ischemic cardiac remodeling in rats. J Cell Mol Med. 2011Mar;15(3):514-24

103. DelCarratoreR,CarpiA,BeffyP,LubranoV,GiorgettiL,MasertiBE,CarluccioMA,SimiliM,IervasiG,BalzanS.Itraconazoleinhibits

HMEC-1angiogenesis.BiomedicineandPharmacotherapy2012;66(4):312-317104. MolinaroS,IervasiG,LorenzoniV,CoceaniM,LandiP,SrebotV,MarianiF,L’AbbateA,PingitoreA.PersistenceofMortalityRiskin

PatientsWithAcuteCardiacDiseasesandMildThyroidDysfunction.AmJMedSci.2012;343(1):65-70105. GalliE,MarchiniM,SabaA,BertiS,TonaccheraM,VittiP,ScanlanTS,IervasiG,ZucchiR.Detectionof3-IodothyronamineinHuman

Patients:APreliminaryStudy.JClinEndocrinolMetab.2012;97(1):E69-E74Oct26106. BalzanS,DelCarratoreR,NicoliniG,BeffyP, LubranoV,ForiniF, IervasiG.Proangiogenic effectofTSH inhumanmicrovascular

endothelialcellstroughtitsmembranereceptor.JClinEndocrinolMetab.2012;97(5):1763-1770107. MarchettiI,IervasiG,MazzantiMC,LessiF,TomeiS,NaccaratoAG,AretiniP,AlbertiB,DiCoscioG,andBevilacquaG.Detectionof

the BRAFV600E mutation in fine needle aspiration cytology of thyroid papillary microcarcinoma cells selected by manualmacrodissection:aneasytooltoimprovethepreoperativediagnosis.Thyroid2012;22(3):292-298

108. IervasiG,ForiniF,SabatinoL.Aglassofwine:howgoodisgood?Theresveratrollesson.CritCareMed2012;40(11):3098-99109. IervasiG,BottoniA,FilideiE.IsrecombinanthumanTSHaseffectiveasthyroidhormonewithdrawalindetectionandtreatmentof

metastaticdifferentiatedthyroidcancer?ExpertReviewofEndocrinologyandMetabolism2012;7(12):633-35110. ColletTH,GusseklooJ,BauerDC,denElzenWP,CappolaAR,BalmerP,IervasiG,ÅsvoldBO,SgarbiJA,VölzkeH,GencerB,MacielRM,

Molinaro S, Bremner A, Luben RN,Maisonneuve P, Cornuz J, Newman AB, KhawKT,Westendorp RG, Franklyn JA, Vittinghoff E,Walsh JP, Rodondi N; Thyroid Studies Collaboration. Subclinical hyperthyroidism and the risk of coronary heart disease andmortality.ArchInternMed.2012May28;172(10):799-809.

111. Fontana M., Passino C., Poletti R., Zyw L., Prontera C., Scarlattini M., Clerico A., Emdin M., Iervasi G. Low Triiodothyronine and

exercisecapacityinheartfailure.InternationalJournalofCardiology2012112. CantinottiM,LorenzoniV,StortiS,MoschettiR,MurziB,MarottaM,CrocettiM,MolinaroS,ClericoA,PortmanM,IervasiG.Thyroid

andbrainnatriueticpeptideresponseinchildrenundergoingcardiacsurgeryforcongenitalheartdisease:age-relatedvariationsandprognosticvalue.CirculationJournal2013;77(1):188-97

113. Marraccini P, Bianchi M, Bottoni A, Mazzarisi A, Coceani M, Molinaro S, Lorenzoni V, Landi P, Iervasi G. Prevalence of thyroid

disfunction and effect of contrastmedium on thyroidmetabolism in cardiac patients undergoing on coronary angiography. ActaRadiologica2013;54(1):42-47

114. Iervasi G., Nicolini G. Thyroid hormone and cardiovascular system: from basic concepts to clinical application. Internal and

EmergencyMedicine,2013;8:71-74115. Vassalle C., Iervasi G. Cathepsin K – A classical bone biomarker in cardiovascular disease: the heart is not alone anymore.

Atherosclerosis2013;228:36-37


116. NicoliniG,PittoL,KusmicC,BalzanS,SabatinoL,IervasiG,ForiniF.Newinsightintomechanismofcardioprotectionmediatedbythyroidhormones.JournalofThyroidResearch2013;2013:264387

117. CarpiA, RossiG,NicoliniA, IervasiG, RussoM,Mechanick J.Does largeneedle aspirationbiopsy addpain to the thyroidnodule

evaluation?PLoSOne.2013;8(3):e58016.118. CantinottiM,ClericoA, IervasiG.Age-anddisease-relatedvariations inB-typenatriureticpeptideresponseafterpediatriccardiac

surgery.JThoracCardiovascSurg.2013May;145(5):1415-16119. Adamopoulos S, Gouziouta A,Mantzouratou P, Laoutaris ID, Dritsas A, CokkinosDV,Mourouzis I, Sfyrakis P, Iervasi G, Pantos C.

Thyroidhormonesignalingisalteredinresponsetophysicaltraininginpatientswithend-stageheartfailureandmechanicalassistdevices:potentialphysiologicalconsequences?InteractCardiovascThoracSurg2013;17(4):664-68

120. MenicucciD,SebastianiL,CompariniA,PingitoreA,GhelarducciB,L’AbbateA,IervasiG,GemignaniA.Minimalchangesofthyroid

axis activity influence brain functions in young females affected by subclinical hypothyroidism. Archives Italiennes de Biologie2013;151:1-10

121. Cantinotti M, Iervasi G, Clerico A. B-type natriuretic peptide in children undergoing pediatric cardiac surgery: just a marker of

diseaseseveritystronglyrelatedtoageormuchmore?TheJournalofThoracicandCardiovascularSurgery2014;147(1):541122. WeltmanNY,PingitoreA, IervasiG.Relationof triiodothyronine tosubclinicalmyocardial injury inpatientswithchestpain.AmJ

Cardiology2013;112(3):465-66123. CantinottiM,AssantaN,MurziB,IervasiG,SpadoniI.Echocardiographicdefinitionofrestrictivepatentforamenovale(PFO).Heart

2014;100:264-265124. BalzanS,DelCarratoreS,Nardulli C, SabatinoL, SabatinoL, IervasiG.The stimulative effect ofT3andT4onhumanmyocardial

endothelialcellproliferation,migrationandangiogenesis.JClinExpCardiology2013;4:12125. Saba A, Donzelli R, Colligiani D, Raffaelli A, Nannipieri M, Kusmic C, Dos Remedios CG, Simonides WS, Iervasi G, Zucchi R.

QuantificationofThyroxineand3,5,3’–TriiodothyronineinHumanandAnimalHeartsbyaNovelLiquidChromatography-TandemMassSpectometryMethod.HormMetabRes2014;46:1-7

126. CerilloAG,StortiS,KallushiE,HaxhiademiD,MiceliA,MurziM,BertiS,GlauberM,ClericoA, IervasiG.The lowtriiodothyronine

syndrome: a strong predictor of low cardiac output and death in patients undergoing coronary artery bypass grafting. Annals ofThoracicSurgery2014

127. CantinottiM,ScaleseM,MurziB,AssantaN,Spadoni I,FestaP,DeLuciaV,CrocettiM,MarottaM,MolinaroS,LopezL, IervasiG.

Echocardiographic nomograms for ventricular, valvular and arterial dimensions in caucasian children with a special focus onneonates,infantsandtoddlers.JAmSocEchocardiography2014;27(2):179-181

128. CantinottiM,AssantaN,CrocettiM,MarottaM,MurziB,IervasiG.Limitationsofcurrentnomogramsinpediatricechocardiography:

justthetipoftheiceberg-acallforstandardization.JAmSocEchocardiography2014;27(3):339129. GuiducciL,IervasiG,QuininesGalvanA.Ontheparadoxinsulinresistance/insulinhypersensivityandobesity:twotalesofthesame

story.ExpRevCardiovasc.Ther.201412(6):637:642130. ArviaC,SicilianoV,ChatzianagnostouK,LawsG,QuinonesGalvanA,MamminiC,BertiS,MolinaroS,IervasiG;Conventionalinsulin

vs insulin infusion therapy in acute coronary syndrome diabetic patients; World J Diabetes. 2014 Aug 15;5(4):562-8. doi:10.4239/wjd.v5.i4.562

131. SabatinoL,IervasiG,PingitoreA;Thyroidhormoneandheartfailure:frommyocardialprotectiontosystemicregulation.;ExpertRev

CardiovascTher.2014Oct;12(10):1227-36.doi:10.1586/14779072.2014.957674.Epub2014Sep1132. Forini F, Kusmic C, Nicolini G, Mariani L, Zucchi R, Matteucci M, Iervasi G, Pitto L; Triiodothyronine prevents cardiac

ischemia/reperfusion mitochondrial impairment and cell loss by regulating miR30a/p53 axis. Endocrinology.2014Nov;155(11):4581-90.doi:10.1210/en.2014-1106.Epub2014Aug19.

133. SabatinoL,LubranoV,BalzanS,KusmicC,DelTurcoS, IervasiG.ThyroidhormonedeiodinasesD1,D2,andD3areexpressed in

human endothelial dermal microvascular line: effects of thyroid hormones. Mol Cell Biochem.2015 Jan;399(1-2):87-94. doi:10.1007/s11010-014-2235-8.Epub2014Oct11.

134. BuneviciusA,IervasiG,BuneviciusR.Neuroprotectiveactionsofthyroidhormonesandlow-T3syndromeasabiomarkerinacute

cerebrovasculardisorders.ExpertRevNeurother.2015Mar;15(3):315-26.doi:10.1586/14737175.2015.1013465.Epub2015Feb11.

135. ForiniF,NicoliniG,IervasiG.Mitochondriaaskeytargetsofcardioprotectionincardiacischemicdisease:roleofthyroidhormone

triiodothyronine.IntJMolSci.2015Mar19;16(3):6312-36.doi:10.3390/ijms16036312.


135. ChakerL,BaumgartnerC,denElzenWP,IkramMA,BlumMR,ColletTH,BakkerSJ,DehghanA,DrechslerC,LubenRN,HofmanA,PortegiesML,MediciM,IervasiG,StottDJ,FordI,BremnerA,WannerC,FerrucciL,NewmanAB,DullaartRP,SgarbiJA,CeresiniG,Maciel RM,WestendorpRG, Jukema JW, ImaizumiM, Franklyn JA, BauerDC,Walsh JP, Razvi S, KhawKT, Cappola AR, VölzkeH,FrancoOH,Gussekloo J,RodondiN,PeetersRP;ThyroidStudiesCollaboration.SubclinicalHypothyroidismandtheRiskofStrokeEvents and Fatal Stroke: An Individual Participant Data Analysis. J Clin Endocrinol Metab. 2015 Jun;100(6):2181-91. doi:10.1210/jc.2015-1438.Epub2015Apr9.

137. Cantinotti M, Giordano R, Scalese M, Molinaro S, Murzi B, Assanta N, Crocetti M, Marotta M, Ghione S, Iervasi G. Strengths and

limitations of current pediatric bloodpressurenomograms: a global overviewwith a special emphasis on regional differences inneonatesandinfants.HypertensRes.2015Sep;38(9):577-87.doi:10.1038/hr.2015.45.Epub2015Apr16.

138. Åsvold BO, Vatten LJ, Bjøro T, BauerDC, Bremner A, Cappola AR, Ceresini G, den ElzenWP, Ferrucci L, FrancoOH, Franklyn JA,

GusseklooJ,IervasiG,ImaizumiM,KearneyPM,KhawKT,MacielRM,NewmanAB,PeetersRP,PsatyBM,RazviS,SgarbiJA,StottDJ,TrompetS,VanderpumpMP,VölzkeH,WalshJP,WestendorpRG,RodondiN;ThyroidStudiesCollaboration.Thyroidfunctionwithinthenormalrangeandriskofcoronaryheartdisease:anindividualparticipantdataanalysisof14cohorts.JAMAInternMed.2015Jun;175(6):1037-47.doi:10.1001/jamainternmed.2015.0930.

139. CantinottiM,GiordanoR,ScaleseM,MolinaroS,DellaPinaF,StortiS,ArcieriL,MurziB,MarottaM,PakV,PoliV,IervasiG,KuttyS,Clerico A. Prognostic role of BNP in children undergoing surgery for congenital heart disease: analysis of prediction modelsincorporatingstandardriskfactors.ClinChemLabMed.2015Oct1;53(11):1839-46.doi:10.1515/cclm-2014-1084.

140. CantinottiM,KuttyS,GiordanoR,AssantaN,MurziB,CrocettiM,MarottaM, IervasiG.Reviewandstatus reportofpediatric left

ventricularsystolicstrainandstrainratenomograms.HeartFailRev.2015Sep;20(5):601-12.doi:10.1007/s10741-015-9492-9.141. WangW,GuanH,GerdesAM,IervasiG,YangY,TangYD.ThyroidStatus,CardiacFunction,andMortalityinPatientsWithIdiopathic

DilatedCardiomyopathy.JClinEndocrinolMetab.2015Aug;100(8):3210-8.doi:10.1210/jc.2014-4159.Epub2015Jun8.142. PingitoreA, LimaGP,Mastorci F, QuinonesA, Iervasi G, Vassalle C. Exercise and oxidative stress: potential effects of antioxidant

dietarystrategiesinsports.Nutrition.2015Jul-Aug;31(7-8):916-22.doi:10.1016/j.nut.2015.02.005.Epub2015Feb19.143. FusaroM,GianniniS,GallieniM,NoaleM,TripepiG,RossiniM,MessaP,RigottiP,PatiT,BarbisoniF,PiccoliA,AghiA,AlessiM,

Bonfante L, Fabris F, Zambon S, Sella S, Iervasi G, PlebaniM. Calcimimetic and vitaminD analog use in hemodialyzedpatients isassociatedwithincreasedlevelsofvitaminKdependentproteins.Endocrine.2015Jul1.[Epubaheadofprint]

144. ChatzianagnostouK, IervasiG,VassalleC.ChallengesofLADADiagnosisandTreatment:LessonsFrom2CaseReports.AmJTher.

2015Sep24.[Epubaheadofprint]145 PingitoreA,NicoliniG,KusmicC,IervasiG,GrigoliniP,ForiniF.CardioprotectionandthyroidhormonesHeartFailRev.2016Mar24.

[Epubaheadofprint]146 Sbrana F, Genovesi D, Catapano GA, Panchetti L, Bottoni A, Iervasi G. Dabigatran malabsorption in amiodarone-induced

thyrotoxicosis:aclinicalreport.InternEmergMed.2016Mar17.[Epubaheadofprint]147 NicoliniG,ForiniF,KusmicC,PittoL,MarianiL,IervasiG.Earlyandshort-termtriiodothyroninesupplementationpreventsadverse

post-ischemiccardiacremodeling:roleoftransforminggrowthfactor-β1andanti-fibroticmiRNAsignaling.MolMed.2015Nov23.doi:10.2119/molmed.2015.00140.[Epubaheadofprint]

148 CantinottiM,GiordanoR,ScaleseM,MurziB,AssantaN,SpadoniI,CrocettiM,MarottaM,MolinaroS,KuttyS,IervasiG.Nomograms

formitral inflowDopplerandtissueDopplervelocities inCaucasianchildren. JCardiol.2015Nov9.pii:S0914-5087(15)00321-4.doi:10.1016/j.jjcc.2015.10.004.[Epubaheadofprint]

149 ForiniF,UcciferriN,KusmicC,NicoliniG,CecchettiniA,RocchiccioliS,CittiL,IervasiG.EvidencefromaProteomicApproach.Low

T3 State Is Correlated with Cardiac Mitochondrial Impairments after Ischemia Reperfusion Injury: Int J Mol Sci. 2015 Nov6;16(11):26687-705.doi:10.3390/ijms161125973.

150 FusaroM,PlebaniM,IervasiG,GallieniM.VitaminKDeficiencyinChronicKidneyDisease:EvidenceIsBuildingUp.AmJNephrol.

2016Nov15;45(1):1-3.[Epubaheadofprint]151 JabbarA,PingitoreA,PearceSH,ZamanA,IervasiG,RazviS.Thyroidhormonesandcardiovasculardisease.NatRevCardiol.2016

Nov4.doi:10.1038/nrcardio.2016.174.[Epubaheadofprint]152 ChakerL,BaumgartnerC,denElzenWP,ColletTH,IkramMA,BlumMR,DehghanA,DrechslerC,LubenRN,PortegiesML,IervasiG,

MediciM,StottDJ,DullaartRP,FordI,BremnerA,NewmanAB,WannerC,SgarbiJA,DörrM,LongstrethWTJr,PsatyBM,FerrucciL,MacielRM,WestendorpRG, JukemaJW,CeresiniG, ImaizumiM,HofmanA,BakkerSJ,Franklyn JA,KhawKT,BauerDC,Walsh JP,Razvi S, Gussekloo J, VölzkeH, FrancoOH, CappolaAR, RodondiN, PeetersRP; Thyroid Studies Collaboration.. Thyroid FunctionWithin the Reference Range and the Risk of Stroke: An Individual Participant Data Analysis. J Clin Endocrinol Metab. 2016Nov;101(11):4270-4282.

153 FusaroM,GallieniM,RizzoMA,StucchiA,DelanayeP,CavalierE,MoysésRM,JorgettiV,IervasiG,GianniniS,FabrisF,AghiA,SellaS,

Galli F, Viola V, Plebani M. Vitamin K plasma levels determination in human health. Clin Chem Lab Med. 2016 Oct 12. pii:/j/cclm.ahead-of-print/cclm-2016-0783/cclm-2016-0783.xml.doi:10.1515/cclm-2016-0783.[Epubaheadofprint]

154 SabatinoL,KusmicC,NicoliniG,AmatoR,CasiniG,IervasiG,BalzanS.T3enhancesAng2inrataortainmyocardialI/R:comparison

withleftventricle.JMolEndocrinol.2016Oct;57(3):139-49.doi:10.1530/JME-16-0118.


155 FusaroM,D'AlessandroC,NoaleM,TripepiG,PlebaniM,VeroneseN,IervasiG,GianniniS,RossiniM,TarroniG,LucatelloS,VianelloA, Santinello I, Bonfante L, Fabris F, Sella S, PiccoliA,NasoA, CiurlinoD,AghiA,GallieniM, CupistiA. LowvitaminK1 intake inhaemodialysispatients.ClinNutr.2016Apr28.pii:S0261-5614(16)30070-X.doi:10.1016/j.clnu.2016.04.024.[Epubaheadofprint]

156 CantinottiM,GiordanoR,ScaleseM,MurziB,AssantaN,SpadoniI,MauraC,MarcoM,MolinaroS,KuttyS,IervasiG.Nomogramsfor

two-dimensional echocardiography derived valvular and arterial dimensions in Caucasian children. J Cardiol. 2016 Apr 23. pii:S0914-5087(16)30029-6.doi:10.1016/j.jjcc.2016.03.010.[Epubaheadofprint]

157 CantinottiM,AssantaN,CrocettiM,SpadoniI,IervasiG.ChallengesinInterpretingPediatricNormativeLeftVentricularStrainData

and the Quest for Comprehensive Deformation Nomograms. J Am Soc Echocardiogr. 2016 Jun;29(6):567-8. doi:10.1016/j.echo.2016.03.005.

158 Donzelli R, Colligiani D, Kusmic C, Sabatini M, Lorenzini L, Accorroni A, Nannipieri M, Saba A, Iervasi G, Zucchi R. Effect of

HypothyroidismandHyperthyroidismonTissueThyroidHormoneConcentrationsinRat.EurThyroidJ.2016Mar;5(1):27-34.doi:10.1159/000443523.

159 CantinottiM,GiordanoR,ClementeA,AssantaN,MurziM,MurziB,CrocettiM,MarottaM,ScaleseM,KuttyS,IervasiG.Strengthsand

LimitationsofCurrentAdultNomograms for theAortaObtainedbyNoninvasiveCardiovascular Imaging.Echocardiography.2016Jul;33(7):1046-68.doi:10.1111/echo.13232.Review.

160 WangW,GuanH,FangW,ZhangK,GerdesAM,IervasiG,TangYD.FreeTriiodothyronineLevelCorrelateswithMyocardialInjury

and Prognosis in Idiopathic Dilated Cardiomyopathy: Evidence from Cardiac MRI and SPECT/PET Imaging. Sci Rep. 2016 Dec22;6:39811.doi:10.1038/srep39811.

161 Bunevicius A, Deltuva VP, Tamasauskas S, Smith T, Laws ER, Bunevicius R, Iervasi G, Tamasauskas A.Preoperative low tri-

iodothyronineconcentrationisassociatedwithworsehealthstatusandshorterfiveyearsurvivalofprimarybraintumorpatients.Oncotarget.2017Jan31;8(5):8648-8656.doi:10.18632/oncotarget.14376.

162 CantinottiM,KuttyS,FranchiE,PaterniM,ScaleseM,IervasiG,KoestenbergerM.Pediatricechocardiographicnomograms:Whathas

beendoneandwhatstillneedstobedone.TrendsCardiovascMed.2017Jul;27(5):336-349.doi:10.1016/j.tcm.2017.01.006.Epub2017Jan19.Review.

163 ClericoA,RipoliA,FortunatoA,AlfanoA,CarrozzaC,CorrealeM,DittadiR,GessoniG,MigliardiM,RizzardiS,PronteraC,MasottiS,

ZucchelliG,GuiottoC,IacovazziPA,IervasiG.HarmonizationprotocolsforTSHimmunoassays:amulticenterstudyinItaly.ItalianSectionoftheEuropeanLigandAssaySociety(ELAS).ClinChemLabMed.2017Oct26;55(11):1722-1733.doi:10.1515/cclm-2016-0899.

164 FerranniniE,IervasiG,CobbJ,NdreuR,NannipieriM.Insulinresistanceandnormalthyroidhormonelevels:prospectivestudyand

metabolomic analysis. Am J Physiol Endocrinol Metab. 2017 May 1;312(5):E429-E436. doi: 10.1152/ajpendo.00464.2016. Epub2017Feb28.

165 CantinottiM,GiordanoR,EmdinM,AssantaN,CrocettiM,MarottaM,IervasiG,LopezL,KuttyS.Echocardiographicassessmentof

pediatric semilunar valve disease. Echocardiography. 2017 Sep;34(9):1360-1370. doi: 10.1111/echo.13527. Epub 2017 Mar 31.Review.

166 Cantinotti M, Giordano R, Scalese M, Molinaro S, Storti S, Murzi B, Pak V, Poli V, Iervasi G, Clerico A. Diagnostic accuracy and

prognosticvaluedofplasmaticCystatin-Cinchildrenundergoingpediatriccardiacsurgery.ClinChimActa.2017Aug;471:113-118.doi:10.1016/j.cca.2017.05.031.Epub2017May26.

167 Cantinotti M, Giordano R, Assanta N, Murzi B, Melo M, Franchi E, Crocetti M, Iervasi G, Kutty S. Strengths, Limitations, and

GeographicalDiscrepanciesintheEligibilityCriteriaforSportParticipationinYoungPatientsWithCongenitalHeartDisease.ClinJSportMed.2017Jul21.doi:10.1097/JSM.0000000000000474.[Epubaheadofprint]

168 CantinottiM, GiordanoR, ScaleseM, Franchi E, CoranaG, AssantaN,Maura C,MarcoM,Molinaro S, KoestenbergerM, Iervasi G.

Nomogramsforechocardiographicrightventricularsub-costalviewdimensionsinhealthyCaucasianchildren:Anewapproachtomeasuretherightventricle.JCardiol.2018Feb;71(2):181-186.doi:10.1016/j.jjcc.2017.07.015.Epub2017Oct12.

169 FusaroM,GallieniM,AghiA,IervasiG,RizzoMA,StucchiA,NoaleM,TripepiG,NickolasT,VeroneseN,FabrisF,GianniniS,CalòL,

PiccoliA,MereuMC,CosmaiL,FerraroA,MagonaraF,SpinelloM,SellaS,PlebaniM.CigarettesmokingisassociatedwithdecreasedBone Gla-protein (BGP) levels in hemodialysis patients. Curr Vasc Pharmacol. 2017 Sep 19. doi:10.2174/1570161115666170919182421.[Epubaheadofprint]

170 Guarino D, Nannipieri M, Iervasi G, Taddei S, Bruno RM. The Role of the Autonomic Nervous System in the Pathophysiology of

Obesity.FrontPhysiol.2017Sep14;8:665.doi:10.3389/fphys.2017.00665.eCollection2017.Review.171 Hartwig V, Guiducci L,MarinelliM, Pistoia L, Tegrimi TM, Iervasi G, Quinones-GalvanA, L'Abbate A.Multimodal Imaging for the

Detection of Brown Adipose Tissue Activation inWomen: A Pilot Study Using NIRS and Infrared Thermography. J Healthc Eng.2017;2017:5986452.doi:10.1155/2017/5986452.Epub2017Sep14.

172 BuneviciusA,DeltuvaV,LawsER, IervasiG,TamsauskasA,BuneviciusR.PreoperativeN-terminalpro-B-typenatriureticpeptide

concertationandprognosisofbraintumorpatients:a5-yearfollowupstudy.SciRep.2017Nov7;7(1):14775.doi:10.1038/s41598-017-15394-6.


173 Cantinotti M, Giordano R, Corsini I, Dani C, Scalese M, Murzi B, Assanta N, Spadoni I, Molinaro S, Kutty S, Iervasi G, Franchi E.EchocardiographicnomogramsforupperabdominalaortaDopplersystolicwavevaluesandsysto-diastolicdiametersvariationsinchildren.JCardiol.2018Apr;71(4):394-400.doi:10.1016/j.jjcc.2017.09.016.Epub2017Nov10.

174 FusaroM,MereuMC,AghiA,IervasiG,GallieniM.VitaminKandbone.ClinCasesMinerBoneMetab.2017May-Aug;14(2):200-206.

doi:10.11138/ccmbm/2017.14.1.200.Epub2017Oct25.Review.175 ZhangK,WangW,ZhaoS,KatzSD,IervasiG,GerdesAM,TangYD.Long-termprognosticvalueofcombinedfreetriiodothyronineand

lategadoliniumenhancementinnonischemicdilatedcardiomyopathy.ClinCardiol.2018Jan;41(1):96-103.doi:10.1002/clc.22858.Epub2018Jan23.

176 Bunevicius A, Radziunas A, Tamasauskas S, Tamasauskas A, Laws ER, Iervasi G, Bunevicius R, Deltuva V. Prognostic role of high

sensitivity C-reactive protein and interleukin-6 in glioma andmeningioma patients. J Neurooncol. 2018 Jun;138(2):351-358. doi:10.1007/s11060-018-2803-y.Epub2018Feb19.

177 CantinottiM,ScaleseM,GiordanoR,FranchiE,AssantaN,MarottaM,ViacavaC,MolinaroS,IervasiG,SantoroG,KoestenbergerM.

NormativeData for Left andRightVentricular Systolic Strain inHealthyCaucasian ItalianChildrenbyTwo-Dimensional Speckle-TrackingEchocardiography.JAmSocEchocardiogr.2018Jun;31(6):712-720.e6.doi:10.1016/j.echo.2018.01.006.Epub2018Mar8.

178 Razvi S, Jabbar A, Pingitore A, Danzi S, Biondi B, Klein I, Peeters R, Zaman A, Iervasi G. Thyroid Hormones and Cardiovascular

FunctionandDiseases.JAmCollCardiol.2018Apr24;71(16):1781-1796.doi:10.1016/j.jacc.2018.02.045.Review.179 MeuweseCL,vanDiepenM,CappolaAR,SarnakMJ,ShlipakMG,BauerDC,FriedLP,IacovielloM,VaesB,DegryseJ,KhawKT,Luben

RN,ÅsvoldBO,BjøroT,VattenLJ,deCraenAJM,TrompetS,IervasiG,MolinaroS,CeresiniG,FerrucciL,DullaartRPF,BakkerSJL,JukemaJW,KearneyPM,StottDJ,PeetersRP,FrancoOH,VölzkeH,WalshJP,BremnerA,SgarbiJA,MacielRMB,ImaizumiM,OhishiW,DekkerFW,RodondiN,GusseklooJ,denElzenWPJ.Lowthyroidfunctionisnotassociatedwithanaccelerateddeteriorationinrenalfunction.ThyroidStudiesCollaboration.NephrolDialTransplant.2018Apr18.doi:10.1093/ndt/gfy071.[Epubaheadofprint]

180 Sabatino L, Balzan S, Kusmic C, Iervasi G. Modification of gene expression profiling related to renin-angiotensin system in an

ischemia/reperfusionratmodelafterT3infusion.MolCellBiochem.2018May8.doi:10.1007/s11010-018-3364-2.[Epubaheadofprint]

181 Sabatino L, Costagli C, Lapi D, Del Seppia C, Federighi G, Balzan S, Colantuoni A,Iervasi G, Scuri R. Renin-Angiotensin System

Responds to ProlongedHypotensive Effect Induced byMandibular Extension in SpontaneouslyHypertensive Rats. Front Physiol.2018Nov15;9:1613.doi:10.3389/fphys.2018.01613.eCollection2018.

182 CantinottiM,ScaleseM,GiordanoR,FranchiE,AssantaN,MolinaroS,IervasiG,SantoroG,KoestenbergerM,KuttyS.LeftandRight

AtrialStraininHealthyCaucasianChildrenbyTwo-DimensionalSpeckle-TrackingEchocardiography.JAmSocEchocardiogr.2019Jan;32(1):165-168.e3.doi:10.1016/j.echo.2018.10.002.Epub2018Nov17.

183 CantinottiM,ScaleseM,GiordanoR,AssantaN,SantoroG,PaterniM,IervasiG,ChiappaE,KuttyS,KostenbergerM.Limitationsof

Current Fetal Echocardiography Nomograms for 2D Measures: A Critical Overview and Analysis for Future Research. J Am SocEchocardiogr.2018Dec;31(12):1368-1372.e10.doi:10.1016/j.echo.2018.09.018.Epub2018Oct16.

184 Forini F, Nicolini G, Kusmic C, D'Aurizio R, Rizzo M, Baumgart M, Groth M, Doccini S, Iervasi G, Pitto L. Integrative analysis of

differentially expressed genes andmiRNAs predicts complex T3-mediated protective circuits in a rat model of cardiac ischemiareperfusion.SciRep.2018Sep14;8(1):13870.doi:10.1038/s41598-018-32237-0.

185 GoriniF, IervasiG,CoiA,PittoL,BianchiF.TheRoleofPolybrominatedDiphenylEthers inThyroidCarcinogenesis: Is It aWeak

HypothesisoraHiddenReality?FromFactstoNewPerspectives.IntJEnvironResPublicHealth.2018Aug24;15(9).pii:E1834.doi:10.3390/ijerph15091834.Review.

186 WopereisDM,DuPuyRS,vanHeemstD,WalshJP,BremnerA,BakkerSJL,BauerDC,CappolaAR,CeresiniG,DegryseJ,DullaartRPF,

FellerM,FerrucciL,FlorianiC,FrancoOH,IacovielloM,IervasiG,ImaizumiM,JukemaJW,KhawKT,LubenRN,MolinaroS,NauckM,PatelKV,PeetersRP,PsatyBM,RazviS,SchindhelmRK,vanSchoorNM,StottDJ,VaesB,VanderpumpMPJ,VölzkeH,WestendorpRGJ,RodondiN,CobbaertCM,GusseklooJ,denElzenWPJ;ThyroidStudiesCollaboration.TheRelationBetweenThyroidFunctionand Anemia: A Pooled Analysis of Individual Participant Data. J Clin Endocrinol Metab. 2018 Oct 1;103(10):3658-3667. doi:10.1210/jc.2018-00481.

187 WangWY,ZhangK,ZhaoW,GerdesAM,IervasiG,TangYD.Freetriiodothyroninelevelcorrelateswithstatinresponsivenessinacute

myocardialinfarction.JGeriatrCardiol.2018Apr;15(4):290-297.doi:10.11909/j.issn.1671-5411.2018.04.009.188 FusaroM,D'ArrigoG,PitinoA,IervasiG,TentoriF,RobinsonB,AghiA,BieberB,McculloghK,FabrisF,PlebaniM,GianniniS,Gallieni

M,TripepiG. Increasedriskofbone fractures inhemodialysispatients treatedwithprotonpump inhibitors inrealworld: resultsfrom theDialysis Outcomes and Practice Patterns Study (DOPPS).J BoneMiner Res. 2019 Jul 31. doi: 10.1002/jbmr.3842. [Epubaheadofprint]

189 ForiniF,NicoliniG,KusmicC,IervasiG.ProtectiveEffectsofEuthyroidismRestorationonMitochondriaFunctionandQualityControl

inCardiacPathophysiology.IntJMolSci.2019Jul10;20(14).pii:E3377.doi:10.3390/ijms20143377.Review.190 CantinottiM,KoestenbergerM,SantoroG,AssantaN,FranchiE,PaterniM,IervasiG,D'AndreaA,D'AscenziF,GiordanoR,Galderisi

M.Normalbasic2Dechocardiographicvaluestoscreenandfollowuptheathlete'sheartfromjuniorstoadults:Whatisknownandwhatismissing.Acriticalreview.EurJPrevCardiol.2019Jul2:2047487319862060.doi:10.1177/2047487319862060.[Epub

191 Lubrano V, Pingitore A, Traghella I, Storti S, Parri S, Berti S, Ndreu R, Andrenelli A, Palmieri C,Iervasi G, Mastorci F, Vassalle C.

Emerging Biomarkers of Oxidative Stress in Acute and Stable Coronary Artery Disease: Levels and Determinants. Antioxidants


(Basel).2019May1;8(5).pii:E115.doi:10.3390/antiox8050115.192 CantinottiM,ScaleseM,GiordanoR,FranchiE,MarcheseP,AssantaN,MolinaroS,PaterniM,IervasiG,KoestenbergerM,KuttyS.

Three-DimensionalEchocardiographyDerivedNomogramsforLeftVentricularVolumesinHealthyCaucasianItalianChildren.JAmSocEchocardiogr.2019Jun;32(6):794-797.e1.doi:10.1016/j.echo.2019.01.020.Epub2019Apr2.Noabstractavailable.

193 CantinottiM,GiordanoR,ScaleseM,FranchiE,AssantaN,MolinaroS,MarcheseP,PaterniM,IervasiG,KuttyS,KoestenbergerM.

Nomograms of pulsed Doppler velocities, times, and velocity time integrals for semilunar valves and great arteries in healthyCaucasian children. Int J Cardiol. 2019 Jun 15;285:133-139. doi: 10.1016/j.ijcard.2019.03.001. Epub 2019 Mar 3. No abstractavailable.

194 Jalil B,HartwigV,MoroniD, Salvetti O, Benassi A, Jalil Z, Pistoia L,Minutoli Tegrimi T, Quinones-GalvanA,Iervasi G, L'AbbateA,

GuiducciL.APilotStudyofInfraredThermographyBasedAssessmentofLocalSkinTemperatureResponseinOverweightandLeanWomenduringOralGlucoseToleranceTest.JClinMed.2019Feb19;8(2).pii:E260.doi:10.3390/jcm8020260.

195 FusaroM,GallieniM,AghiA,RizzoMA,IervasiG,NickolasTL,FabrisF,MereuMC,GianniniS,SellaS,GiustiA,PitinoA,D'ArrigoG,

RossiniM,GattiD,RaveraM,DiLulloL,BellasiA,BrunoriG,PiccoliA,TripepiG,PlebaniM.Osteocalcin(boneGLAprotein)levels,vascular calcifications, vertebral fractures and mortality in hemodialysis patients with diabetes mellitus. J Nephrol. 2019Aug;32(4):635-643.doi:10.1007/s40620-019-00595-1.Epub2019Feb13.

196 PingitoreA,MastorciF,PiaggiP,AquaroGD,MolinaroS,RavaniM,DeCaterinaA,TrianniG,NdreuR,BertiS,VassalleC,IervasiG.

UsefulnessofTriiodothyronineReplacementTherapyinPatientsWithSTElevationMyocardialInfarctionandBorderline/ReducedTriiodothyronineLevels(fromtheTHIRSTStudy).AmJCardiol.2019Mar15;123(6):905-912.doi:10.1016/j.amjcard.2018.12.020.Epub2018Dec18.

197 Voges I, Giordano R, Koestenberg M, Marchese P, Scalese M, Ait-Ali L, Santoro G,Iervasi G, Valverde I, Kutty S, Cantinotti M.

Nomograms for Cardiovascular Magnetic Resonance Measurements in the Pediatric Age Group: To Define the Normal and theExpected Abnormal Values in Corrected/Palliated Congenital Heart Disease: A Systematic Review. J Magn Reson Imaging. 2019May;49(5):1222-1235.doi:10.1002/jmri.26614.Epub2019Jan7.Review.

198 Bunevicius, A., Laws, E.R., Saudargiene, A., Tamasauskas, A., Iervasi, G., Deltuva, V., Smith, T.R., Bunevicius, R. Common genetic

variationsofdeiodinasegenesandprognosisofbraintumorpatients.Endocrine.Volume66,Issue3,1December2019,Pages563-572

199 Ravera,M.,Nickolas,T.,Plebani,M., Iervasi,G.,Aghi,A.,Khairallah,P.,Gallieni,M.,Mereu,M.C.,Giannini,S.,Sella,S.,Zaninotto,M.,

Paoletti,E.,Bussalino,E.,DiLullo,L.,Bellasi,A.,Cosmai,L.,Foramitti,M.,Malberti,F.,Brandi,M.L.,Ferrari,S.,Tripepi,G.,Fusaro,M.Overweight-obesity is associated with decreased vitamin K2 levels in hemodialysis patients. Clinical Chemistry and LaboratoryMedicine2020

200 Cappellani, D., Papini, P., Pingitore, A., Tomisti, L.,Mantuano,M., Di Certo, A.M.,Manetti, L.,Marconcini, G., Scattina, I., Urbani, C.,

Morganti,R.,Marcocci,C.,Materazzi,G.,Iervasi,G.,Martino,E.,Bartalena,L.,Bogazzi,F.ComparisonBetweenTotalThyroidectomyandMedical Therapy for Amiodarone-Induced Thyrotoxicosis. The Journal of clinical endocrinology andmetabolismVolume 105,Issue1,1January2020

201 Gorini,F.,Bustaffa,E.,Coi,A.,Iervasi,G.,Bianchi,F.Bisphenolsasenvironmentaltriggersofthyroiddysfunction:Cluesandevidence.

InternationalJournalofEnvironmentalResearchandPublicHealth,2020,17(8),2654.202 Cantinotti, M., Scalese, M., Giordano, R., Franchi, E., Marchese, P., Vicava, C., Assanta, N., Iervasi, G., Kutty, S., Koestenberger, M.

Pediatricnomogramsforleftventriclebiplane2DvolumesinhealthyCaucasianchildren.Echocardiography.Volume37,Issue6,1June2020,Pages971-975

203 Cantinotti,M.,Koestenberger,M.,Santoro,G.,Assanta,N.,Franchi,E.,Paterni,M.,Iervasi,G.,D'Andrea,A.,D'Ascenzi,F.,Giordano,R.,

Galderisi,M.Normalbasic2Dechocardiographicvaluestoscreenandfollowuptheathlete'sheartfromjuniorstoadults:Whatisknownandwhatismissing.Acriticalreview.EuropeanJournalofPreventiveCardiology.Volume27,Issue12,1August2020,Pages1294-1306

204 Fusaro,M.,Cosmai,L.,Evenepoel,P.,Nickolas,T.L.,Cheung,A.M.,Aghi,A.,Tripepi,G.,Plebani,M.,Iervasi,G.,Vettor,R.,Zaninotto,M.,

Ravera,M.,Foramitti,M.,Giannini,S.,Sella,S.,Gallieni,M.VitaminKandkidneytransplantation.Nutrients.OpenAccessVolume12,Issue9,September2020,Articlenumber2717,Pages1-13.

205 Forini,F.,Nicolini,G.,Kusmic,C.,D'Aurizio,R.,Mercatanti,A.,Iervasi,G.,Pitto,L.T3CriticallyAffectstheMhrt/Brg1AxistoRegulate

theCardiacMHCSwitch:RoleofanEpigeneticCross-Talk.Cells.Volume9,Issue10,24September2020206 Forini,F.,Canale,P.,Nicolini,G.,Iervasi,G.Mitochondria-targeteddrugdeliveryincardiovasculardisease:Alongroadtonano-cardio

medicine.Pharmaceutics,2020,12(11),pp.1-24,1122207 Sabatino,L.,Kusmic,C., Iervasi,G.Modificationofcardiacthyroidhormonedeiodinasesexpressioninan ischemia/reperfusionrat

modelafterT3infusion.MolecularandCellularBiochemistry,2020,475(1-2),pp.205-214. CHAPTERSINBOOK1. CarpiA,IervasiG,NicoliniA,BianchiR,UrbanoU,DiCoscioG.COneyearexperiencewithaspirationofthyroidnodules.In“Advances

inthyroidneoplasia”,AndreoliM.,RobbinsJ.,MonacoE.,Eds,FieldEducationalItalia,Roma,1981,pp.293-300


2. BianchiR, IervasiG “ LaTiroide” in “Semeiologia eDiagnostica funzionale”, PaseroG,GiordaniR,Eds, CasaEditriceAmbrosiana,

Milano1985,pp.562-5733. Bianchi R, Iervasi G, Molea N, Cazzuola F, Ferdeghini M, Pilo A Kinetic studies of thyroid hormones in familial disalbuminemic

hyperthyroxinemia(FDH)andincongenitalTBGelevation(HTBG).PlenumPress,NewYork,1986,pp.499-5034. Iervasi G, Boni G, FerdeghiniM “I Dosaggi Radioimmunologici” in “Immunologia inMedicina” Dammacco F Ed, Casa Editrice Edi

Ermes,Milano1989,pp.1618-16305. IervasiG,BertiS,VitekF,BiaginiA,ClericoA,PiloA,TurchiS,BarattoMT,CazzuolaF,BianchiRKineticsof theatrialnatriuretic

peptideinhumansbyanewtracermethod.In“Radioactiveisotopesinclinicalmedicineandresearch”.F.K.Schattauered.SpringerVerlag,Stuttgart,NewYork1992,pp.322-5

6. Berti S, Palmieri C, BoniniR, RavaniM, ClericoA, Iervasi G, Gazzetti P, Pugliese S, BiaginiAAcuteEnoximone effect on systemic

hemodynamicrenal functionandhormonalactivation inpatientswithheart failure. In“MechanismandTherapyofHeartFailure”eds.P.K.Singal,R.E.BeamishandN.S.Dhalla,Boston,KluwerAcademicPublishers,1994

7. IervasiG, ClericoA, Berti S, PiloA, Vitek F,Manfredi C, IasconeMR,Maffei S, BiaginiAPeripheral resistance to atrial natriuretic

peptide in patients with idiopathic dilated cardiomyopathy. In “Mechanism and Therapy of Heart Failure” eds. P.K. Singal, R.E.BeamishandN.S.Dhalla,Boston,KluwerAcademicPublishers,1994

8. VitekF,PiloA,IervasiG,ClericoA,BertiS,IasconeMR,ManfrediC,BiaginiA,BianchiR,DonatoLCirculatorymodelforinvivokinetic

studiesofatrialnatriureticpeptide(ANP) inhumans.Computers inCardiology,BethesdaSeptember25-28,1994, IEEEComputerSocietyPress,LosAlamos1994,pp.385-8

9. IervasiG,EmdinMControlloneuroendocrinodelsistemacardiovascolare. In“TrattatodiCardiologiaANMCO”,ExcerptaMedica–

ESIStampaMedica,Milano2000pp.133-148.10. EmdinM.,IervasiG.Scompensocardiacoesistemaneuroendocrino.IQuadernidelCNR,2001,PrimulaMultimediaS.r.L11. IervasiG,ZucchelliGC.Diagnosticabiochimicadellemalattietiroidee.In“Trattatoitalianodimedicinadilaboratorio.CasaEditrice

Piccin,Vol.VII,Capitolo15,2008pp.421–44812. Iervasi G, Pingitore A. Heart failure, Iodine intake and thyroid hormones. In “ Comprehensive handbook on iodine: nutritional,

endocrineandpathologicalaspects.V.Preedy,G.N.Burrow,R.R.WatsonEds.,ElsevierInc.,OxfordAcademicPress2009:pp1073-1086

13. IervasiG,FommeiE.HypertensionandHypothyroidism,athyroiddysfunctionfrequentlyassociatedwithaabnormaldietaryiodine

intake.In“Comprehensivehandbookoniodine:nutritional,endocrineandpathologicalaspects.V.Preedy,G.N.Burrow,R.R.WatsonEds.,ElsevierInc.,OxfordAcademicPress2009:pp1057-1071

14. IervasiG.,SabatinoL.,NicoliniG.Lowtriiodothyroninesyndromeasapowerfulpredictorofdeathinheartfailure.In:“Thyroidand

heartfailure:frompathophysiologytoclinics”.G.Iervasi,A.PingitoreEds,Springer–VerlagItalia2009:pp.179-190.15. PingitoreA. ,IervasiG.Thyroidhormone inheart failure:potential therapeutic implications. In“Frontieres inCardiovascularDrug

Discovery”,A.Rahman,MIChoudharyEds,BenthamSciencePublishers2010,Vol1pp16. Bottoni A., Lorenzoni G., Iervasi G. Tecniche diagnostiche per lo studio della tiroide. In “Fondamenti di medicina nucleare”. D.

Volterrani,P.A.Erba,G.MarianiEds.Springer–VerlagItalia2010.pp617-650.TheundersignedauthorizestoprocessherpersonaldataforthepurposeshereininaccordancewiththetermsintheLegislativeDecreeNo196of30/06/2003

Pisa,30/11/2020

GiorgioIervasi

2020-12-10T14:15:43+0100Iervasi Giorgio

E UROPEAN CURRICULUM VITAE · 2020. 12. 11. · Page 1 - Curriculum vitae of Giorgio Iervasi...

Documents

Transcript of E UROPEAN CURRICULUM VITAE · 2020. 12. 11. · Page 1 - Curriculum vitae of Giorgio Iervasi...