Collected Papers 2015

Faculty of Dental Science

Kyushu University

＜分子口腔解剖学＞

Yamaza T, Alatas FS, Yuniartha R, Yamaza H, Fujiyoshi JK, Yanagi Y, Yoshimaru K, Hayashida M, Matsuura T, Aijima R, Ihara K, Ohga S, Shi S, Nonaka K and Taguchi T: In vivo hepatogenic capacity and therapeutic potential of stem cells from human exfoliated deciduous teeth in liver fibrosis in mice. Stem Cell Res. Ther. 6: 171, 2015 (DOI: 10.1186/s13287-015-0154-6) Ma L, Aijima R, Hoshino Y, Yamaza H, Tomoda E, Tanaka Y, Sonoda S, Song G, Zhao W, Nonaka K, Shi S and Yamaza T: Transplantation of mesenchymal stem cells ameliorates secondary osteoporosis through interleukin-17-impaired functions of recipient bone marrow mesenchymal stem cells in MRL/lpr mice. Stem Cell Res. Ther. 6: 104, 2015 (DOI: 10.1186/s13287-015-0091-4) Yoneme H, Hatakeyama J, Danjo A, Oida H, Yoshinari M, Aijima R, Murata N, Watanabe T, Oki Y and Kido MA: Milk basic protein supplementation enhances fracture healing in mice. Nutrition 31: 399-405, 2015 (DOI: 10.1016/j.nut.2014.08.008) Aijima R, Wang B, Takao T, Mihara H, Kashio M, Ohsaki Y, Zhang JQ, Mizuno A, Suzuki M, Yamashita Y, Masuko S, Goto M, Tominaga M and Kido MA: The thermosensitive TRPV3 channel contributes to rapid wound healing in oral epithelia. FASEB J. 29: 182-192, 2015 (DOI: 10.1096/fj.14-251314) Kukita T, Takahashi A, Zhang J-Q and Kukita A: Membrane nanotube formation in osteoclastogenesis. In "Methods in Molecular Biology" Pfannkuche K ed. Springer N.Y. USA 1313: 193-202, 2015 Qu P-F, Kukita A, Li Y-J, Moriyama K, Lei L and Kukita T: Involvement of deoxyadenosine and adenosine deaminase in the methotrexatre-induced suppression of inflammatory bone destruction. In "Adenosine Receptors: Pharmacology, Functions and Therapeutic Aspects" Warrick K ed. NOVA Science Publisher, N.Y. USA Chaptor V: 143-164, 2015

＜口腔細胞工学＞ Otani T, Mizokami A, Hayashi Y, Gao J, Mori Y, Nakamura S, Takeuchi H and Hirata M: Signalling pathway for adiponectin expression in adipocytes by osteocalcin. Cell. Signal. 27: 532-544, 2015 (DOI: 10.1016/j.cellsig.2014.12.018) Toyoda H, Saito M, Sato H, Tanaka T, Ogawa T, Yatani H, Kawano T, Kanematsu T, Hirata M and Kang Y: Enhanced desensitization followed by unusual resensitization in GABAA receptors in phospholipase C-related catalytically inactive protein-1/2 double-knockout mice. Pflügers Archiv–Eur. J. Physiol. 467: 267-284, 2015 (DOI: 10.1007/s00424-014-1511-5) Nagano K, Takeuchi H, Gao J, Mori Y, Otani T, Wang DG and Hirata M: Tomosyn is a novel Akt substrate mediating insulin-dependent GLUT4 exocytosis. Int. J. Biochem. Cell Biol. 62: 62-71, 2015 (DOI: 10.1016/j.biocel.2015.02.013) Wang DG, Takeuchi H, Gao J, Zhang Z and Hirata M: Hetero-oligomerization of C2 domains of phospholipase C-related but catalytically inactive protein and synaptotagmin-1. Adv. Biol. Regul. 57: 120-129, 2015 (DOI: 10.1016/j.jbior.2014.09.001) Tsuka S, Aonuma F, Higashi S, Ohsumi T, Nagano K, Mizokami A, Yasukochi-Kawakubo T, Masaki C, Hosokawa R, Hirata M and Takeuchi H: Promotion of insulin-induced glucose uptake in C2C12 myotubes by osteocalcin. Biochem. Biophys. Res. Commun. 459: 437-442, 2015 (DOI: 10.1016/j.bbrc.2015.02.123) Toyoda H, Saito M, Sato H, Kawano T, Kawakami S, Yatani H, Kanematsu T, Hirata M and Kang Y: Enhanced lateral inhibition in the barrel cortex by deletion of phospholipase C-related catalytically inactive protein-1/2 in mice. Pflügers Archiv–Eur. J. Physiol. 467: 1445-1456, 2015 (DOI: 10.1007/s00424-014-1592-1) Kotani M, Matsuda M, Murakami A, Takahashi I, Katagairi T and Hirata M: Involvement of PRIP (phospholipase C-related but catalytically inactive protein) in BMP-induced Smad signaling in osteoblast differentiation. J. Cell. Biochem. 116: 2814-2823, 2015 (DOI: 10.1002/jcb.25228)

＜口腔機能分子科学＞ Ni J, Wu Z, Peters C, Yamamoto K, Qing H and Nakanishi H: The critical role of proteolytic relay through cathepsin B and E on the phenotypic changes of microglia/ macrophage. Journal of Neuroscience 35: 12488-12501, 2015 (DOI: 10.1523/JNEUROSCI.1599-15.2015)                                             ＊本研究成果は日刊工業新聞（9月8日、九大、脳の炎症 仕組み解明 - 免疫細胞を傷害性に変化）ならびに科学新聞（10月9日、

脳内免疫担当ミクログリア - 傷害性と保護性の極性転換スイッチを発見）に掲載。

Okada R, Wu Z, Zhu A, Ni J, Zhang J, Yoshimine Y, Peters C, Saftig P and Nakanishi H: Cathepsin D deficiency induces oxidative damage in brain pericytes and impairs the blood-brain barrier. Molecular and Cellular Neuroscience 64: 51-60, 2015 (DOI: 10.1016/j.mcn.2014.12.002) Zhu A, Wu Z, Meng J, McGeer PL, Zhu Y, Nakanishi H and Wu S: The neuroprotective effects of Ratanasampil on oxidative stress-mediated neuronal damage in human neuronal SH-SY5Y cells. Oxidative Medical Cellular Longevity 2015: 792342, 2015 (DOI: 10.1155/2015/792342) Wu Z and Nakanishi H���: Lessons from microglia aging for the link between inflammatory bone disorders and Alzheimer's disease.��� Journal of Immunological Research 2015: 471342, 2015 (DOI: 10.1155/2015/471342) Nakanishi H and Wu Z: Downward spiral of periodontitis and diabetes into Alzheimer's disease: Extending healthy life expectancy through oral health. Journal of Oral Bioscience 57: 139-142, 2015 (DOI: 10.1016/j.job.2015.05.002) Hayashi Y and Nakanishi H: BK channel in microglia as a potent therapeutic molecular target for neuropathic pain. Journal of Oral Bioscience 57: 131-134, 2015 (DOI: 10.1016/j.job.2015.03.001)

＜口腔機能解析学＞ Yoshida R, Noguchi K, Shigemura N, Jyotaki M, Takahashi I, Margolskee RF and Ninomiya Y: Leptin suppresses mouse taste cell responses to sweet compounds. Diabetes 64: 3751-3762, 2015 (DOI: 10.2337/db14-1462) Goto TK, Yeung AW, Suen JL, Fong BS and Ninomiya Y: High resolution time-intensity recording with synchronized solution delivery system for the human dynamic taste perception. J. Neurosci. Methods 245: 147-155, 2015 (DOI: 10.1016/j.jneumeth.2015.02.023) Niki M, Jyotaki M, Yoshida R, Yasumatsu K, Shigemura N, DiPatrizio NV, Piomelli D and Ninomiya Y: Modulation of sweet taste sensitivities by endogenous leptin and endocannabinoids in mice. J. Physiol. 593: 2527-2545, 2015 (DOI: 10.1113/JP270295) Shigemura N: Angiotensin II and taste sensitivity. Japanese Dental Science Review 51: 51-58, 2015 (DOI: 10.1016/j.jdsr.2014.09.005) Takai S, Yasumatsu K, Inoue M, Iwata S, Yoshida R, Shigemura N, Yanagawa Y, Drucker DJ, Margolskee RF and Ninomiya Y: Glucagon-like peptide-1 is specifically involved in sweet taste transmission. FASEB J. 29: 2268-2280, 2015 (DOI: 10.1096/fj.14-265355) Shigemura N: Modulation of taste responsiveness by angiotensin II. Food Science and Technology Research 21: 757-764, 2015 (DOI: 10.3136/fstr.21.757) Yasumatsu K, Manabe T, Yoshida R, Iwatsuki K, Uneyama H, Takahashi I and Ninomiya Y: Involvement of multiple taste receptors in umami taste: analysis of gustatory nerve responses in metabotropic glutamate receptor 4 knockout mice. J. Physiol. 593: 1021-1034, 2015 (DOI: 10.1113/jphysiol.2014.284703)

＜口腔予防医学＞

Ahmad A, Furuta M, Shinagawa T, Takeuchi K, Takeshita T, Shimazaki Y and Yamashita Y: Association of periodontal status with liver abnormalities andmetabolic syndrome. J. Oral Sci. 57: 335-343, 2015 (DOI: 10.2334/josnusd.57.335) Takeuchi K, Izumi M, Furuta M, Takeshita T, Shibata Y, Kageyama S, Ganaha S and Yamashita Y: Posterior teeth occlusion associated with cognitive function in nursing home older residents: a cross-sectional observational study. PLoS One 10: e0141737, 2015 (DOI: 10.1371/journal.pone.0141737) Sakamoto M, Li D, Shibata Y, Takeshita T, Yamashita Y and Ohkuma M: Porphyromonas pasteri sp. nov. isolated from human saliva. Int. J. Syst. Evol. Microbiol. 65: 2511-2515, 2015 (DOI: 10.1099/ijs.0.000294) Furuta M, Shimazaki Y, Tanaka S, Takeuchi K, Shibata Y, Takeshita T, Nishimura F and Yamashita Y: Gender-specific associations of serum antibody to Porphyromonas gingivalis and inflammatory markers. Biomed. Res. Int. 2015: 897971, 2015 (DOI: 10.1155/2015/897971) Hashiba T, Takeuchi K, Shimazaki Y, Takeshita T and Yamashita Y: Chewing xylitol gum improves self-rated and objective indicators of oral health status under conditions interrupting regular oral hygiene. Tohoku J. Exp. Med. 235: 39-46, 2015 (DOI: 10.1620/tjem.235.39) Takeuchi K, Furuta M, Takeshita T, Shibata Y, Shimazaki Y, Akifusa S, Ninomiya T, Kiyohara Y and Yamashita Y: Risk factors for reduced salivary flow rate in a Japanese population: the Hisayama Study. Biomed. Res. Int. 2015: 381821, 2015 (DOI: 10.1155/2015/381821) Takeshita T, Yasui M, Shibata Y, Furuta M, Saeki Y, Eshima N and Yamashita Y: Dental plaque development on a hydroxyapatite disk in young adults observed by using a barcoded pyrosequencing approach. Sci. Rep. 5: 8136, 2015 (DOI: 10.1038/srep08136) Takeuchi K, Furuta M, Takeshita T, Shibata Y, Shimazaki Y, Akifusa S, Ninomiya T, Kiyohara Y and Yamashita Y: Serum antibody to Porphyromonas gingivalis and periodontitis progression: the Hisayama Study. J. Clin. Periodontol. 42: 719-725, 2015 (DOI: 10.1111/jcpe.12431)

Suzuki R, Kikutani T, Yoshida M, Yamashita Y and Hirayama Y: Prognosis-related factors concerning oral and general conditions for homebound older adults in Japan. Geriatr. Gerontol. Int. 15: 1001-1006, 2015 (DOI: 10.1111/ggi.12382) Moritani K, Takeshita T, Shibata Y, Ninomiya T, Kiyohara Y and Yamashita Y: Acetaldehyde production by major oral microbes. Oral Dis. 21: 748-754, 2015 (DOI: 10.1111/odi.12341) Zakaria MN, Takeshita T, Shibata Y, Maeda H, Wada N, Akamine A and Yamashita Y: Microbial community in persistent apical periodontitis: a 16S rRNA gene clone library analysis. Int. Endod. J. 48: 717-728, 2015 (DOI: 10.1111/iej.12361) Genkai S, Kikutani T, Suzuki R, Tamura F, Yamashita Y and Yoshida M: Loss of occlusal support affects the decline in activities of daily living in elderly people receiving home care. J. Prosthodont. Res. 59: 243-248, 2015 (DOI: 10.1016/j.jpor.2015.06.003) Sato Y, Aida J, Takeuchi K, Ito K, Koyama S, Kakizaki M, Sato M, Osaka K and Tsuji I: Impact of loss of removable dentures on oral health after the great east Japan earthquake: a retrospective cohort study. J. Prosthodont. 24: 32-36, 2015 (DOI: 10.1111/jopr.12210)

＜小児口腔医学＞ Masuda K, Kawano S, Yamaza H, Sakamoto T, Kiyoshima T, Nakamura S and Nonaka K: Complete resolution of a calcifying cystic odontogenic tumor with physiological eruption of a dislocated permanent tooth after marsupialization in a child with a mixed dentition: a case report. World J. Surg. Oncol. 13: 277, 2015 (DOI: 10.1186/s12957-015-0697-0) Shimokawa I, Komatsu T, Hayashi N, Kim SE, Kawata T, Park S, Hayashi H, Yamaza H, Chiba T and Mori R: The life-extending effect of dietary restriction requires Foxo3 in mice. Aging Cell 14: 707-709, 2015 (DOI: 10.1111/acel.12340) Kamohara R, Yamaza H, Tsuchiya T, Komatsu T, Park S, Hayashi H, Chiba T, Mori R, Otabe S, Yamada K, Nagayasu T and Shimokawa I: Overexpression of the adiponectin gene mimics the metabolic and stress resistance effects of calorie restriction, but not the anti-tumor effect. Exp. Gerontol. 64: 46-54, 2015 (DOI: 10.1016/j.exger.2015.02.011)

＜歯科矯正学＞

Albogha MH, Takahashi I and Sawan MN: Early treatment of anterior open bite: Comparison of the vertical and horizontal morphological changes induced by magnetic bite-blocks and adjusted rapid molar intruders. Korean J. Orthod. 45(1): 38-46, 2015 (DOI: 10.4041/kjod.2015.45.1.38) Deguchi T, Terao F, Aonuma T, Kataoka T, Sugawara Y, Yamashiro T and Takano-Yamamoto T: Outcome assessment of lingual and labial appliances compared with cephalometric analysis, peer assessment rating, and objective grading system in Angle Class II extraction cases. Angle Orthod. 85(3): 400-407, 2015 (DOI: 10.2319/031014-173.1) Saito K, Fukumoto E, Yamada A, Yuasa K, Yoshizaki K, Iwamoto T, Saito M, Nakamura T and Fukumoto S: Interaction between fibronectin and β1 integrin is essential for tooth development. PLoS One. 10(4): e0121667, 2015 (DOI: 10.1371/journal.pone.0121667) Umeda M, Terao F, Miyazaki K, Yoshizaki K and Takahashi I: MicroRNA-200a regulates the development of mandibular condylar cartilage. J. Dent. Res. 94: 795-802, 2015 (DOI: 10.1177/0022034515577411) Kobuke S, Suzuki S, Hoshino H, Haruyama N, Nishimura F and Shiba H: Relationship between length variations in Ser/Asp-rich repeats in phosphophoryn and in vitro precipitation of calcium phosphate. Arch. Oral Biol. 60(9): 1263-1272, 2015 (DOI: 10.1016/j.archoralbio) Albogha MH and Takahashi I. Generic finite element models of orthodontic mini-implants: Are they reliable? J. Biomech. 48(14): 3751-3756, 2015 (DOI: 10.1016/j.jbiomech.2015.08.015)

＜生体材料学＞

Nagai H, Fujioka-Kobayashi M, Fujisawa K, Ohe G, Takamaru N, Hara K, Uchida D, Tamatani T, Ishikawa K and Miyamoto Y: Effects of low crystalline carbonate apatite on proliferation and osteoblastic differentiation of human bone marrow cells. J. Mater. Sci.: Mater. Med. 26(2): 99-107, 2015 (DOI: 10.1007/s10856-015-5431-5) Shi X, Xu L, Munar ML and Ishikwa K: Hydrothermal treatment for TiN as abrasion resistant dental implant coating and its fibroblast response. Materials Science and Engineering: C. 49: 1-6, 2015 (DOI: 10.1016/j.msec.2014.12.059) Ishikawa K, Tram NXT, Tsuru K and Toita R: Fabrication of porous calcite using chopped nylon fiber and its evaluation using rats. Journal of Material Science: Materials in Medicine. 26: 94, 2015 (DOI: 10.1007/s10856- 015-5432-4) Rashid AN, Tsuru K and Ishikawa K: Effect of calcium-ozone treatment on chemical biological properties of polyethylene terephthalate. Journal of Biomedical materials Research part B. 103(4): 853-860, 2015 (DOI: 10.1002/ jbm.b.33260) Cahyanto A, Maruta M, Tsuru K, Matsuya S and Ishikawa K: Fabrication of bone cement that fully transforms to carbonate apatite. Dental Materials Journal 34(3): 394-401, 2015 (DOI: 10.4012/dmj.2014-328) Valanezhad A, Tsuru K and Ishikawa K: Fabrication of strongly attached hydroxyapatite coating on titanium by hydrothermal treatment of Ti-Zn-PO4 coated titanium on CaCl2. Journal of Material Science: Materials in Medicine 26: 212, 2015 (DOI: 10.1007/ s10856-015-5548-6)

Shariff KA, Tsuru K and Ishikawa K: Fabrication of interconnected pore forming α-tricalcium phosphate foam granules cement. Journal of Biomaterials Applications 2015 (DOI: 10.1177/0885328215601939) Tsuru K, Ruslin, Maruta M, Matsuya S and Ishikawa K: Effects of the method of apatite seed crystals addition on setting reaction of α-tricalcium phosphate based apatite cement. Journal of Material Science: Materials in Medicine 26: 244, 2015 (DOI: 10.1007/s10856- 015-5570-8)

Kien PT, Ishikawa K and Tsuru K: Setting reaction of α-TCP spheres and an acidic calcium phosphate solution for the fabrication of fully interconnected macroporous calcium phosphate. Ceramics International 41: 13525-13531, 2015 (DOI: 10.1016/j.ceramint.2015.07.146) Toita R, Sunarso, Rashid AN, Tsuru K and Ishikawa K: Modulation of the osteoconductive property and immune response of poly (ether ether ketone) by modification with calcium ions. J. Mater. Chem. B. 3: 8738-8746, 2015 (DOI: 10.1039/C5TB01679G) Kang JH, Asai D, Toita R, Kawano T and Murata M: Monitoring of phosphorylated peptides by radioactive assay and matrix-assisted laser desorption-ionization time-of-flight mass spectrometry. Amino Acids 47: 2377-2384, 2015 (DOI: 10.1007/s00726-015-2025-y) Ishikawa K, Tram NXT, Tsuru K and Toita R: Fabrication of porous calcite using chopped nylon fiber and its evaluation using rats. J. Mater. Sci. 26: 94-101, 2015 (DOI: 10.1007/s10856-015-5432-4) Toita R, Kawano T, Kang JH and Murata M: Applications of human hepatitis B virus preS domain in bio- and nanotechnology. World J. Gastroenterol. 21: 7400-7411, 2015 (DOI: 10.3748/wjg.v21.i24.7400) Onuma K and Sugiura Y: Metastable intermediate phase during phaset ransformation of calcium phosphates. J. Biotech. Biomater. 5(4): 1000214, 2015 (DOI: 10.4172/2155-952X.1000214) Sugiura Y, Onuma K, Nagao M and Yamazaki A: The effects of immobilized carboxylic-functional groups on the dynamics of phase transformation from amorphous to octacalcium phosphate. Am. Min. 100: 1624-1632, 2015 (DOI: 10.2138/am-2015-5179) Koga N, Tsuru K, Takahashi I and Ishikawa K: Effects of humidity on calcite block fabrication using calcium hydroxide compact. Ceramics International 41: 9482-9487, 2015 (DOI: 10.1016/j.ceramint.2015.04.005) Nikaido T, Tsuru K, Melvin M, Maruta M, Matsuya S, Nakamura S and Ishikawa K: Fabrication of β-TCP foam: effects of magnesium oxide as phase stabilizer on its properties. Ceramics International 41: 14245-14250, 2015 (DOI: 10.1016/j.ceramint.2015.07.053)

＜歯科保存学＞ Yuda A, Maeda H, Fujii S, Monnouchi S, Yamamoto N, Wada N, Koori K, Tomokiyo A, Hamano S, Hasegawa D and Akamine A: Effect of CTGF/CCN2 on osteo/cementoblastic and fibroblastic differentiation of a human periodontal ligament stem/progenitor cell line. J. Cell. Physiol. 230: 150-159, 2015 (DOI: 10.1002/jcp.24693) Washio A, Nakagawa A, Nishihara T, Maeda H and Kitamura C: Physicochemical properties of newly developed bioactive glass cement and its effects on various cells. J. Biomed. Mater. Res. B. Appl. Biomater. 103: 373-380, 2015 (DOI: 10.1002/jbm.b.33209) Hasegawa D, Wada N, Maeda H, Yoshida S, Mitarai H, Tomokiyo A, Monnouchi S, Hamano S, Yuda A and Akamine A: Wnt5a induces collagen production by human periodontal ligament cells through transforming growth factor β1-mediated upregulation of periostin expression. J. Cell. Physiol. 230: 2647-2660, 2015 (DOI: 10.1002/jcp.24950) Monnouchi S, Maeda H, Yuda A, Hamano S, Wada N, Tomokiyo A, Koori K, Sugii H, Serita S and Akamine A: Mechanical induction of interleukin-11 regulates osteo/cementoblastic differentiation of human periodontal ligament stem/progenitor cells. J. Periodont. Res. 50: 231-239, 2015 (DOI: 10.1111/jre.12200) Tomokiyo A, Hynes K, Gronthos S, Wada N and Bartold PM: Is there a role for neural crest stem cells in periodontal pegeneration? Curr. Oral Health Rep. 2: 275–281, 2015 (DOI: 10.1007/s40496-015-0073-8)

＜歯周病学＞ Sanui T, Tanaka U, Fukuda T, Toyoda K, Taketomi T, Atomura R, Yamamichi K and Nishimura F: Mutation of Spry2 induces proliferation and differentiation of osteoblasts but inhibits proliferation of gingival epithelial cells. J. Cell. Biochem. 116(4): 628-639, 2015 (DOI: 10.1002/jcb.25014) Hashimoto Y, Matsuzaki E, Higashi K, Takahashi-Yanaga F, Takano A, Hirata M and Nishimura F: Sphingosine-1-phosphate inhibits differentiation of C3H10T1/2 cells into adipocyte. Mol. Cell. Biochem. 401: 39-47, 2015 (DOI: 10.1007/s11010-014-2290-1) Sanui T, Fukuda T, Tanaka U, Toyoda K, Taketomi T and Nishimura F: Spry2 is a novel therapeutic target for periodontal tissue regeneration through fibroblast growth factor receptor signaling and epidermal growth factor signaling. Recep. Clin. Invest. 2: e597, 2015 (DOI: 10.14800/rci.597) Sano T, Iwashita M, Nagayasu S, Yamashita A, Shinjo T, Hashikata A, Asano T, Kushiyama A, Ishimaru N, Takahama Y and Nishimura F: Protection from diet-induced obesity and insulin resistance in mice lacking CCL19-CCR7 signaling. Obesity 23(7): 1460-1471, 2015 (DOI: 10.1002/oby.21127) Shinjo T, Nakatsu Y, Iwashita M, Sano T, Sakoda H, Ishihara H, Kushiyama A, Fujishiro M, Fukushima T, Tsuchiya Y, Kamata H, Nishimura F and Asano T: DPP-IV inhibitor anagliptin exerts anti-inflammatory effects on macrophages, adipocytes, and mouse livers by suppressing NF-κB activation. Am. J. Physiol. Endocrinol. Metab. 309(3): E214-E223, 2015 (DOI: 10.1152/ajpendo.00553. 2014) Shinjo T, Nakatsu Y, Iwashita M, Sano T, Sakoda H, Ishihara H, Kushiyama A, Fujishiro M, Nishimura F and Asano T: High-fat diet feeding significantly attenuates anagliptin-induced regeneration of islets of Langerhans in streptozotocin-induced diabetic mice. Diabetol. Metab. Syndr. 7: 50, 2015 (DOI: 10.1186/s13098-015-0047-y) Kobuke S, Suzuki S, Hoshino H, Haruyama N, Nishimura F and Shiba H: Relationship between length variations in Ser/Asp-rich repeats in phosphophoryn and in vitro precipitation of calcium phosphate. Arch. Oral. Biol. 60(9): 1263-1272, 2015 (DOI: 10.1016/j.archoralbio.2015.05.013) Tanaka U, Sanui T, Fukuda T, Toyoda K, Atomura R, Yamamichi K, Maeda H and Nishimura F: Sprouty2 inhibition promotes proliferation and migration of periodontal ligament cells. Oral Diseases 21: 977-986, 2015 (DOI: 10.1111/odi.12369)

＜クラウンブリッジ補綴学＞ Mine Y, Shuto T, Nikawa H, Kawai T, Ohara M, Kawahara K, Ohta K, Kukita T, Terada Y amd Makihira S: Inhibition of RANKL-dependent cellular fusion in pre-osteoclasts by amiloride and a NHE10-specific monoclonal antibody. Cell Biol. Int. 39: 696-709, 2015 (DOI: 10.1002/cbin.10447) Wachi T, Shuto T, Shinohara Y, Matono Y and Makihira S: Release of titanium ions from an implant surface and their effect on cytokine production related to alveolar bone resorption. Toxicology 327: 1–9, 2015 (DOI: 10.1016/j.tox.2014.10.016)

＜インプラント・義歯補綴学＞ Ayukawa Y, Suzuki Y, Tsuru K, Koyano K and Ishikawa K: Histological comparison in rats between carbonate apatite fabricated from gypsum and sintered hydroxyapatite on bone remodeling. Biomed. Res. Int. 2015: 579541, 2015 (DOI: 10.1155/2015/579541) Tanaka H, Toyoshima T, Atsuta I, Ayukawa Y, Sasaki M, Matsushita Y, Hiraoka R, Koyano K and Nakamura S: Additional effects of platelet-rich fibrin on bone regeneration in sinus augmentation with deproteinized bovine bone mineral: Preliminary results. Implant Dent. 24(6): 669-74, 2015 (DOI: 10.1097/ID.0000000000000306) Ogino Y, Liang R, Mendonca DB, Mendonca G, Nagasawa M, Koyano K and Cooper LF: RhoA-mediated functions in C3H10T1/2 osteoprogenitors are substrate topography-dependent. J. Cell. Physiol. 231(3): 568-75, 2015 (DOI: 10.1002/jcp.25100) Yamasaki Y, Kuwatsuru R, Tsukiyama Y, Matsumoto H, Oki K and Koyano K: Objective assessment of actual chewing side by measurement of bilateral masseter muscle electromyography. Arch. Oral Biol. 60: 1756-1762, 2015 (DOI: 10.1016/j.archoralbio.2015.09.010) Morimoto T, Tsukiyama Y, Morimoto K and Koyano K: Facial bone alterations on maxillary anterior single implants for immediate placement and provisionalization following tooth extraction: a superimposed cone beam computed tomography study. Clin. Oral Implants Res. 26(12): 1383-92014, 2015 (DOI: 10.1111/clr.12480) Yasunami N, Ayukawa Y, Furuhashi A, Atsuta I, Dwi Rakhmatia Y, Moriyama Y, Masuzaki T and Koyano K: Acceleration of hard and soft tissue healing in the oral cavity by a single transmucosal injection of fluvastatin-impregnated poly (lactic-co-glycolic acid) microspheres. An in vitro and rodent in vivo study. Biomed. Mater. 11(1): 015001, 2015 (DOI: 10.1088/1748-6041/11/1/015001) Yan X, Yi Z, Wang X, Jinno Y, Zhang X, Koyano K and Ai H: Different study conditions between dental students in China and Japan. Int. J. Clin. Exp. Med. 8(7): 11396-11403, 2015 Fueki K, Igarashi Y, Maeda Y, Baba K, Koyano K, Sasaki K, Akagawa Y, Kuboki T, Kasugai S and Garrett NR: Effect of prosthetic restoration on oral health-related quality of life in patients with shortened dental arches: A multicentre study. J. Oral Rehabil. 42(9): 701-708, 2015 (DOI: 10.1111/joor.12297) Oshiro W, Ayukawa Y, Atsuta I, Furuhashi A, Yamazoe J, Kondo R, Sakaguchi M, Matsuura Y, Tsukiyama Y and Koyano K: Effects of CaCl2 hydrothermal treatment of titanium implant surfaces on early epithelial sealing. Colloids Surf. B Biointerfaces. 1;131: 141-147, 2015. (DOI: 10.1016/j.colsurfb.2015.04.025)

Yan X, Zhang X, Gao J, Matsushita Y, Koyano K, Jiang X and Ai H: Maxillary sinus augmentation without grafting material with simultaneous implant installation: A three-dimensional finite element analysis. Clin. Implant Dent. Relat. Res. 17(3): 515-524, 2015 (DOI: 10.1111/cid.12254) Matsumoto H, Tsukiyama Y, Kuwatsuru R and Koyano K: The effect of intermittent use of occlusal splint devices on sleep bruxism: a 4-week observation with a portable electromyographic recording device. J. Oral Rehabil. 42(4): 251-258, 2015 (DOI: 10.1111/joor.12251.) Dwi Rakhmatia Y, Ayukawa Y, Furuhashi A, Atsuta I and Koyano K: Fibroblast attachment onto novel titanium mesh membranes for guided bone regeneration. Odontology 103(2): 218-226, 2015 (DOI: 10.1007/s10266-014-0151-8) Ogino Y, Kihara M, Yamada J, Toriya K and Koyano K: Implant treatments for edentulous maxilla with anterior hyperfunction. J. Oral Implantol. 41(6): 731-735, 2015 (DOI: 10.1563/AAID-JOI-D-13-00123) Koyano K and Esaki D: Occlusion on oral implants: current clinical guidelines. J. Oral Rehabil. 42(2): 153-161, 2015 (DOI: 10.1111/joor.12239) Yamada J, Kori H, Tsukiyama Y, Matsushita Y, Kamo M and Koyano K: Immediate loading of complete-arch fixed prostheses for edentulous maxillae after flapless guided implant placement: A 1-year prospective clinical study. Int. J. Oral Maxillofac. Implants 30(1): 184-193, 2015 (DOI: 10.11607/jomi.3679)

＜口腔病理学＞

Ueki K, Matsukuma Y, Masutani K, Tsuchimoto A, Fujisaki K, Torisu K, Tanaka S, Kiyoshima T, Hisano S, Kitazono T and Tsuruya K: Membranoproliferative glomerulonephritis with predominant IgG2 and IgG3 deposition in a patient with IgG4-related disease. BMC Nephrol. 16: 173, 2015 (DOI: 10.1186/s12882-015-0164-8) Someya H, Fujiwara H, Nagata K, Wada H, Hasegawa K, Mikami Y, Jinno A, Sakai H, Koyano K and Kiyoshima T: Thymosin beta 4 is associated with RUNX2 expression via the Smad and Akt signaling pathways in mouse dental epithelial cells. Int. J. Mol. Med. 35:1169-78, 2015 (DOI: 10.3892/ijmm.2015.2118)

＜口腔画像情報学＞

Shimizu M, Okamura K, Kise Y, Takeshita Y, Furuhashi H, Weerawanich W, Moriyama M,

Ohyama Y, Furukawa S, Nakamura S and Yoshiura K: Effectiveness of imaging modalities

for screening IgG4-related dacryoadenitis and sialadenitis (Mikulicz's disease) and for

differentiating it from Sjögren's syndrome (SS), with an emphasis on sonography.

Arthritis Res. Ther. 17: 223, 2015 (DOI: 10.1186/s13075-015-0751-x)

Chikui T, Kitamoto E, Kami Y, Kawano S, Kobayashi K, Kamitani T, Obara M and Yoshiura

K: Dynamic contrast-enhanced MRI of oral squamous cell carcinoma: a preliminary study of

the correlations between quantitative parameters and the clinical stage.

Br. J. Radiol. 88: 20140814, 2015 （DOI: 10.1259/bjr.20140814）

Kitamoto E, Chikui T, Kawano S, Ohga M, Kobayashi K, Matsuo Y, Yoshiura T, Obara M,

Honda H and Yoshiura K: The application of dynamic contrast-enhanced MRI and

diffusion-weighted MRI in patients with maxillofacial tumors.

Acad. Radiol. 22: 210-216, 2015 (DOI: 10.1016/j.acra.2014.08.016)

＜口腔顎顔面外科学＞ Sugi T, Sasaki M, Yamashiro T, Tsuneyoshi T, Arioka M, Matsumoto A, Kumamaru W, Nakano H and Mori Y: Hyperbaric oxygen stimulates the proliferation and differentiation of Raw 264.7 cells. Open Journal of Stomatology 5(12): 309-320, 2015 (DOI: 10.4236-ojst.2015.512037. 2015) Nakano H, Mishima K, Nakano A, Suga H, MiyawakiY, Nakagawa S, Matsumura M, Mori Y and Ueyama Y: Relationships between airway morphology and sleep breathing indices in jaw deformity patients. Journal of Sleep Disorders & Therapy 4(1): 1000187 (DOI: 10.4172/2167-0277.1000187. 2015) Inoue K, Nakano H, Sumida T, Yamada T, Otawa N, FukudaN, Nakajima Y, Kumamaru W, Mishima K, Kouchi M, Takahashi I and Mori Y: A novel measurement method for the morphology of the mandibular ramus using homologous modeling. Dentomaxillofacial Radiology 44: 20150062, 2015 (DOI: 10.1259/dmfr.20150062) Otawa N, Sumida T, Kitagaki H, Sasaki K, Fujibayashi S, Takemoto M, Nakamura T, Yamada T, Mori Y and Matsushita T: Custom-made titanium devices as membranes for bone augmentation in implant treatment: Modeling accuracy of titanium products constructed with selective laser melting. J. Craniomaxillofac. Surg. 43: 1289-1295, 2015 Sumida T, Otawa N, Kamata YU, Kamakura S, Matsushita T, Kitagaki H, Mori S, Sasaki K, Fujibayashi S, Takemoto M, Yamaguchi A, Sohmura T, Nakamura T and Mori Y: Custom-made titanium devices as membranes for bone augmentation in implant treatment: Clinical application and the comparison with conventional titanium mesh. J. Craniomaxillofac. Surg. 43: 2183-2188, 2015 Murase R, Tanaka H, Hamakawa T, Goda H, Tano T, Ishikawa A, Hino S, Sumida T, Nakashiro K and Hamakawa H: Double sentinel lymph node mapping with indocyanine green and 99m-technetium-tin colloid in oral squamous cell. International Journal of Oral and Maxillofacial Surgery 44: 1212-1217, 2015 Sumida T, Otawa N, Kamata YU, Yamada T, Uchida K, Nakano H, Hamakawa H, Yamamoto T, Ueyama Y and Mori Y: A clinical investigation of oral sarcomas at multi-institutions over the past 30 years. Anticancer Research 35: 4551-4555, 2015 Yoshihama N, Yamaguchi K, Chigita S, Mine M, Abe M, Ishii K, Kobayashi Y., Akimoto N, Mori Y, Sugiura T: A novel function of CD82/KAI1 in sialyl Lewis antigen-mediated adhesion of cancer cells: Evidence for an anti-metastasis effect by down-regulation of sialyl Lewis antigens. PLoS One 10(4): e0124743, 2015 (DOI: 10.1371/journal.pone.0124743) Mine M, Yamaguchi K, Sugiura T, Chigita S, Yoshihama N, Yoshihama R, Hiyake N, Kobayashi Y and Mori Y: miR-203 inhibits Frizzled-2 expression via CD82/KAI1 expression in human lung carcinoma cells. PLoS One 10(7): e0131350, 2015 (DOI: 10.1371/journal.pone.0131350)

＜顎顔面腫瘍制御学＞ Maehara T, Moriyama M, Kawano S, Hayashida JN, Furukawa S, Ohta M, Tanaka A, Yamauchi M, Ohyama Y, Kiyoshima T and Nakamura S: Cytokine profiles contribute to understanding the pathogenic difference between Good syndrome and oral lichen planus: two case report and literature review. Medicine 94(14): e704, 2015 (DOI: 10.1097/MD.0000000000000704) Ogata K, Katagiri W, Osugi M, Kawai T, Sugimura Y, Hibi H, Nakamura S and Ueda M: Evaluation of the therapeutic effects of conditioned media from mesenchymal stem cells in a rat bisphosphonate-related osteonecrosis of the jaw-like model. Bone 74: 95-105, 2015 (DOI: 10.1016/j.bone.2015.01.011) Furukawa S, Moriyama M, Tanaka A, Maehara T, Tsuboi H, Iizuka M, Hayashida JN, Ohta M, Saeki T, Notohara K, Sumida T and Nakamura S: Preferential M2 macrophages contribute to fibrosis in IgG4-related dacryoadenitis and sialoadenitis, so-called Mikulicz's disease. Clin. Immunol. 156(1): 9-18, 2015 (DOI: 10.1016/j.clim.2014.10.008) Toyoshima T, Tanaka H, Ayukawa Y, Howashi M, Masuzaki T, Kiyosue T, Koyano K and Nakamaura S: Primary stability of a hybrid implant compared with tapered and cylindrical implants in an ex vivo model. Clin. Implant Dent. Relat. Res. 17(5): 950-956, 2015 (DOI: 10.1111/cid.12205) Maruse Y, Kawano S, Kiyoshima T, Goto Y, Matsubara R, Chikui T, Yoshiga D and Nakamura S: Case of mucoepidermoid carcinoma of the sublingual gland accompanied with extensive dystrophic calcification and intratumoral bone formation. Head & Neck 37(11): E161-164, 2015 (DOI: 10.1002/hed.24036) Ohyama K, Moriyama M, Hayashida JN, Tanaka A, Maehara T, Ieda S, Furukawa S, Ohta M, Imabayashi Y and Nakamura S: Saliva as a potential tool for diagnosis of dry mouth including Sjögren's syndrome. Oral Dis. 21: 224–231, 2015 (DOI: 10.1111/odi.12252) Furukawa S, Moriyama M, Kawano S, Tanaka A, Maehara T, Hayashida JN, Goto Y, Kiyoshima T, Shiratsuchi H, Ohyama Y, Ohta M, Imabayashi Y and Nakamura S: Clinical relevance of Küttner tumour and IgG4-related dacryoadenitis and sialoadenitis. Oral Dis. 21: 257-262, 2015 (DOI: 10.1111/odi.12259) Jinno T, Kawano S, Maruse Y, Matsubara R, Goto Y, Sakamoto T, Hashiguchi Y, Kaneko N, Tanaka H, Kitamura R, Toyoshima T, Jinno A, Moriyama M, Oobu K, Kiyoshima T and Nakamura S: Increased expression of interleukin-6 predicts poor response to chemoradiotherapy and unfavorable prognosis in oral squamous cell carcinoma. Oncol. Rep. 33(5): 2161-2168, 2015 (DOI: 10.3892/or.2015.3838) Ohta M, Moriyama M, Goto Y, Kawano S, Tanaka A, Maehara T, Furukawa S, Hayashida JN, Kiyoshima T, Shimizu M, Arinobu Y and Nakamura S: A case of marginal zone B cell lymphoma mimicking IgG4-related dacryoadenitis and sialoadenitis. World J. Surg. Oncol. 13: 67, 2015 (DOI: 10.1186/s12957-015-0459-z)

Hayashi Y, Moriyama M, Maehara T, Goto Y, Kawano S, Ohta M, Tanaka A, Furukawa S, Hayashida JN, Kiyoshima T, Shimizu M, Chikui T and Nakamura S: A case of mantle cell lymphoma presenting as IgG4-related dacryoadenitis and sialoadenitis, so-called Mikulicz's disease. World J. Surg. Oncol. 13: 225, 2015 (DOI: 10.1186/s12957-015-0644-0) Toyoshima T, Tanaka H, Sasaki M, Ichimaru E, Naito Y, Matsushita Y, Koyano K and Nakamura S: Accuracy of implant surgery with surgical guide by inexperienced clinicians: an in vitro study. Clinical and Experimental Dental Research 1(1): 10-17, 2015 (DOI: 10.1002/cre2.3) Hayashida JN, Minami S, Moriyama M, Toyoshima T, Shinozaki S, Tanaka A, Maehara T and Nakamura S: Differences of stimulated and unstimulated salivary flow rates in the patients with dry mouth. J. Oral Maxillofac. Surg. Med. Pathol. 27(1): 96-101, 2015 (DOI: 10.1016/j.ajoms.2014.04. 011) Mitate E, Kubota K, Ueki K, Inoue R, Inoue R, Momii K, Sugimori H, Maehara Y and Nakamura S: Speaking tracheostomy tube and modified mouthstick stylus in a ventilator-dependent patient with spinal cord injury. Case Rep. Emerg. Med. 320357, 2015 (DOI: 10.1155/2015/320357) Khosroshahi A, Wallace ZS, Crowe JL, Akamizu T, Azumi A, Carruthers MN, Chari ST, Della-Torre E, Frulloni L, Goto H, Hart PA, Kamisawa T, Kawa S, Kawano M, Kim MH, Kodama Y, Kubota K, Lerch MM, Löhr M, Masaki Y, Matsui S, Mimori T, Nakamura S, Nakazawa T, Ohara H, Okazaki K, Ryu JH, Saeki T, Schleinitz N, Shimatsu A, Shimosegawa T, Takahashi H, Takahira M, Tanaka A, Topazian M, Umehara H, Webster GJ, Witzig TE, Yamamoto M, Zhang W, Chiba T and Stone JH: Second International Symposium on IgG4-Related Disease: International consensus guidance statement on the treatment of IgG4-related disease. Arthritis & Rheum. 67(7): 1688-1699, 2015 (DOI: 10.1002/art.39132)

＜歯科麻酔学＞

Fujiwara S, Kawakubo Y, Mori S, Tachihara K, Toyoguchi I and Yokoyama T: Effect of planecta and ROSE™ on the frequency characteristics of blood pressure-transducer kits. J. Clin. Monit. Comput. 29(6): 681-689, 2015 (DOI: 10.1007/s10877-014-9650-y) Ito S, Karube N, Hirokawa J, Sako S and Yokoyama T: The effect of the use of a stabilizer and different height settings on the stability of the dental chair when performing high-quality chest compressions. Emerg. Med. (Los Angel) 5: 268. 2015 (DOI: 10.4172/2165-7548.1000268)

＜口腔総合診療科＞ Wada N, Tomokiyo A, Gronthos S and Bartold PM: Immunomodulatory properties of PDLSC and relevance to periodontal regeneration. Curr. Oral Health Rep. 2: 245-251, 2015 (DOI: 10.1007/s40496-015-0062-y) Takarada T, Sumi Y and Higuchi Y: Influence of SOC on the mental health status of postgraduate trainee dentists in Japan. Int. Arch. Addict. Res. Med. 1: 012, 2015 Takarada T, Asada T, Sumi Y and Higuchi Y: Noncontact monitoring of respiration by dynamic air-pressure sensor. Anesth. Prog. 62: 100-105, 2015 (DOI: 10.2344/12-00020.1) Tsuda H, Moritsuchi Y, Higuchi Y and Tsuda T: Oral health under use of continuous positive airway pressure and interest in alternative therapy in patients with obstructive sleep apnea: a questionnaire‐based survey. Gerodontology 2015 (DOI: 10.1111/ger.12184) Yasuma F, Tsuda H and Sawamura A: A case of obstructive sleep apnea syndrome, whose sole complaint of night sweat was eliminated with continuous positive airway pressure. Journal of Sleep Disorders & Therapy 4: 203-204, 2015 (DOI: 10.4172/2167-0277.1000203)