Reactions 1464, p11 - 10 Aug 2013

SBromocriptine

Reversible cerebral vasoconstriction syndrome withischaemic stroke: case report

A 32-year-old woman developed reversible cerebralvasoconstriction syndrome (RCVS) with ischaemic stroke,while receiving bromocriptine.

The woman had started receiving a 7-day course of oralbromocriptine 2.5mg twice a day to suppress lactation; shehad given birth about 1 year earlier. After 7 days ofbromocriptine, she was admitted to a hospital with transientleft-sided weakness, dysarthria and a severe headache.Transient ischaemic attack with right middle cerebral arterystenosis was suspected following MRI and MRA investigation.

The woman started receiving low-dose aspirin. She wasadmitted to a different hospital 9 days after the onset of hersymptoms, with severe, recurrent headache which worsenedon her second day in hospital. She developed left-sidedweakness and dysarthria. RCVS was suspected and shereceived nimodipine for 14 days; her headache, dysarthria andhemiparesis gradually improved. At follow-up 6 months later,her symptoms had completely resolved.

Author comment: "We describe here a case ofbromocriptine-induced RCVS with ischaemic stroke arising1 year after the birth of a second baby."Kim YS, et al. Delayed ischemic stroke associated with bromocriptine-inducedreversible cerebral vasoconstriction syndrome. Neurological Sciences 34: 409-411,No. 3, Mar 2013. Available from: URL: http://dx.doi.org/10.1007/s10072-012-1015-z - South Korea 803091198

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Reactions 10 Aug 2013 No. 14640114-9954/13/1464-0001/$14.95 Adis © 2013 Springer International Publishing AG. All rights reserved