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    Each phospholipid molecule has a polar head

    (hydrophilic) and a pair of non-polar tails

    (hydrophobic ). Phospolipids in mambrane plasma

    arrange themselves into bilayer.

    The phospholipid bilayer acts as a barrier whichisolates the two sides of the membrane.

    Cholesterol molecules help to stabilise and

    strengthen the plasma membrane, making it

    flexible , yet less permeable to water soluble

    substances such as ions.

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    There are various types of protein which are either

    partially or fully embedded in the membrane.

    Pore protein forms a channel whereas carrier protein

    acts as a carrier.

    Some membrane proteins that have carbohydrates

    attached to them are called gycoproteins.

    The phospholipid bilayer, proteins and othercomponents are not rigid or static but form a

    dynamic and flexible structure.

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    Function of the Plasma Membrane

    Protects the cell.

    Separates the intracellular components from theextracellular environment.

    Controls what enters and exits the cell

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    N

    ecessities for the Movement of Su

    bstancesacross the Plasma Membrane

    To transport nutrients into the cell.

    For gases exchange

    To excrete metabolic waste.

    To maintain the pH value and ionicconcentration of the cell.

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    Permeability of the Phospholipids Bilayer

    The permeability of the phospholipids bilayer

    is determined by:

    the size

    and polarityof the substances pass through it.

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    Although the hydrophobic tails of

    phospholipids prevent polar molecules to passthrough it, but because of the small molecular

    size of water , it can slide between the

    phospholipids bilayer move through the pores.

    Pore proteins allow small water-soluble

    molecules and ions to pass through the plasma

    membrane.

    Large water-soluble molecules such as amino

    acids and glucose use the carrier proteins to

    pass through the plasma membrane.

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    What is passive transport?

    Passive transport is the movement of substances

    across the cell membrane without the use of energy

    by the cell.

    During passive transport, substances move down

    their concentration gradient, hence no energy is

    required.

    Passive transports can happen through three

    different channels, namely

    lipid bilayer

    pore protein

    carrier protein

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    What is diffusion?

    Diffusion is the movement of particles from a highdensity region to a low density region. No energy is

    needed and no membrane involves in diffusion.

    The Dynamic Equilibrium

    Diffusion will continue until the concentration in all

    region is the same. When this happen, we say it hasreached the dynamic equilibrium.

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    Factors Affecting the Rate of Diffusion (How fast

    diffusion happens)

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    Particles that Move Through the Plasma

    Membrane Through Diffusion

    Substances soluble in fat: fatty acid, glycerol,

    some vitamins (A,D,E,K)

    Neutral particles: water, oxygen, carbondioxide,

    Example of Diffusion

    Between alveoli and blood capillaries in the

    lung during gases exchange.

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    What is Osmosis?

    Osmosis is the diffusion of a water through a semi-

    permeable membrane, from a solution oflow solute

    concentration to a solution with high solute

    concentration.

    It is a physical process in which a solvent moves,

    without input of energy, across a semi-permeable

    membrane separating two solutions of different

    concentrations.

    Important Points:

    It is the diffusion of water (normally) through a semi-

    permeable membrane.

    It is from a dilute solution to a more concentratedsolution.

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    What is Facilitated Diffusion?

    Facilitated diffusion is the passive transport of substances acrossthe plasma membrane with the help of transport proteins such

    as the channel protein and the carrier protein.

    Substances Pass through the Plasma Membrane through

    Facilitated Diffusion

    Particles undergo facilitated diffusion are the particles that cannot

    diffuse through the phospholipid bilayer such as large particles

    such as glucose, amino acids, proteins and nucleic acids

    Some ions such as the sodium ions and chloride ions

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    2 Types of Transport Protein

    Facilitated diffusion occurs through 2 types of transport protein, namely

    1.Channel Protein (Pore protein)

    2.Carrier Protein

    Mechanism ofFacilitated Diffusion

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    What is Active Transport?

    Active transport is the movement of substances acrossthe plasma membrane of cells against the

    concentration gradient (From lower concentration to

    higher concentration).

    Since it is against the concentration gradient, energy is

    needed in the process.

    Video below shows how particles are transported

    through the carrier protein in active transport. Take

    notes that the process only happens when the carrier

    protein receives energy from an ATP.

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    Basic Requirements in Active Transport

    Presence of the carrier protein

    Presence ofATP (Adenosine Triphosphate)

    Function of the ATP

    ATP is the source of energy in active transport. It suppliesenergy to the carrier protein to carry out the process. It

    is converted into ADP (Adenosine Diphosphate) after the

    reaction.

    Examples of Active Transport

    Intake of mineral ions by the root hairs of a plant.

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    What is Hypotonic Solution?

    Hypotonic solution is the solution that has higher waterpotential than the other solution.

    Water Concentration and Solute Concentration of a Cellin a Hypotonic Solution

    Water concentration: Water concentration inside the cell

    is lower than outside the cell.

    Solute Concentration: Solute concentration inside the

    cell is higher than outside the cell.

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    Effect of Hypotonic Solution on Animal Cell

    1. If an animal cell such as red blood cell is placed into a hypotonic

    solution, water molecules is transported into the red blood

    cells by osmosis (as shown in the diagram above).

    2. The red blood cells will inflate and finally burst because the thin

    membrane cannot withstand the high pressure inside the cell.

    3. The red blood cells are said to undergo haemolysis.

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    Effect of Hypotonic Solution on Plant Cell1.When a plant cell is placed in a hypotonic solution, water molecules is transported

    into the cell by osmosis.

    2.The water is then stored in vacuole causing it to expand and exerts pressure on

    the cell wall. This pressure is called turgor pressure.

    3.The turgor pressure caused the plant cell to become firm orturgid.

    4.The rigid cell wall prevents cell from bursting.

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    What is Isotonic Solution?

    In isotonic solutions, both solutions have equal waterpotential.

    Water Concentration and Solute Concentration of a

    Cell in a Isotonic Solution

    Water concentration and solute concentration are

    equal in both solutions.

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    1. If an animal cell such as red blood cell is placed into a isotonic solution, amount

    of water molecules is transported into the red blood cells by osmosis is equal

    to the amount of water molecules transported out from the cell (as shown in thediagram above).

    2. Therefore the amount of water in the cell remain unchanged.

    3. The red blood cells maintain their shape.

    Effect of Isotonic Solution on Animal Cell

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    Effect of Isotonic Solution on Plant Cell

    1. When a plant cell is placed in an isotonic solution, solute

    concentration in the external solution is equal to the solute

    concentration i the cell sap.

    2.Therefore the rate of diffusion of water into the cell is equal

    to the rate of diffusion of water out from the cell.

    3. As a result, the shape of the cell remain unchanged.

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    What is Hypertonic Solution?

    Hypertonic solution is the solution that has lowerwater potential than the other solution.

    Water Concentration and Solute Concentration

    of a Cell in a Hypertonic Solution

    Water concentration: Water concentration inside

    the cell is higher than outside the cell.

    Solute Concentration: Solute concentration inside the

    cell is lower than outside the cell.

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    Effect of Hypertonic Solution on Animal Cell

    1.If an animal cell such as red blood cell is placed into a hypertonic

    solution, water molecules is transported out from the red blood

    cells by osmosis (as shown in the diagram above).

    2. The red blood cells will shrink due to the lost of water from the cell

    and probably die.

    3. The red blood cells are said to undergo crenation .

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    Effect of Hypertonic Solution on Plant Cell

    1. When a plant cell is placed in a hypotonic solution, water molecules is

    transported out from the cell by osmosis.

    2. The vacuole and cytoplasm are then shrink due to lost of water.

    3. The plasma membrane is pulled away from the cell wall.

    4.The process is called plasmolysed.