B9902002　王立中B9902040　張力常

Thrombus &Myocardial Infarction

Thrombus (harmful blood clotting)

• Hemostasis: helpful blood clotting (wound healing)

Thrombosis: harmful blood clotting (circumstances of clot formation)

Arteries Stroke Heart attack

Veins Deep vein thrombosis (DVT) Pulmonary embolism Retinal vein occlusions

Deep vein thrombosis (DVT) Pulmonary embolism

Retinal vein occlusions

What happen to the clot?

DissolutionPropagation → Occlusive thrombusEmbolization → ThromboembolusOrganization1)Incorporation2)Recanalization

Myocardial Infarction

Caused by thrombus

Blockage of coronary arteries

Damage or death of cardiac muscle tissue

Ventricular fibrillation (VF)Ventricular tachycardia (VT)

Diagnosis

Cardiac Muscle

Heart Attack

Immediate Treatment

Time Is MuscleNitroglycerin

→ metabolite: NO as EDRF (Endothelium-derived relaxing factor)

Aspirin→ antiplatelet effect→ inhibiting Cyclooxygenase (COX) then the production of thromboxane

CPR / AEDOxygen

Thank you for your attention= )