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Characterization of absorbed and produced constituents in goat plasma urine and faeces from the herbal medicine Gelsemium elegans by using high- performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry Meng-Ting Zuo 1,2 , Zi-Yuan Wang 1,2 , Kun Yang 1 , Yu-Juan Li 1,2 , Chong-Ying Huang 1,2 , Yan-Chun Liu 1,2 , Hui Yu 1,2 , Xue-Jiao Zhao 1,2 , Zhao-Ying Liu 1,2,3 * 1 College of Veterinary Medicine, Hunan Agricultural University, Changsha 410128, Hunan, China 2 Hunan Engineering Technology Research Center of Veterinary Drugs, Hunan Agricultural University, Changsha 410128, Hunan, China 3 Hunan Key Laboratory of Traditional Chinese Veterinary Medicine, Hunan Agricultural University, Changsha 410128, Hunan, China

Transcript of ars.els-cdn.com · Web viewMeng-Ting Zuo 1,2, Zi-Yuan Wang 1,2, Kun Yang 1, Yu-Juan Li 1,2,...

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Characterization of absorbed and produced constituents in goat plasma urine and faeces from the

herbal medicine Gelsemium elegans by using high-performance liquid chromatography coupled with

quadrupole time-of-flight mass spectrometryMeng-Ting Zuo1,2, Zi-Yuan Wang1,2, Kun Yang1, Yu-Juan Li1,2, Chong-Ying Huang1,2, Yan-Chun Liu1,2, Hui Yu1,2, Xue-Jiao Zhao1,2, Zhao-Ying Liu 1,2,3*

1College of Veterinary Medicine, Hunan Agricultural University, Changsha 410128, Hunan, China2 Hunan Engineering Technology Research Center of Veterinary Drugs, Hunan Agricultural University, Changsha 410128, Hunan, China

3 Hunan Key Laboratory of Traditional Chinese Veterinary Medicine, Hunan Agricultural University, Changsha 410128, Hunan, China

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m/z 309.1582 m/z 323.1739

m/z 515.2005 (+176) m/z 339.1698

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m/z 515.2024 (+176) m/z 337.1542

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m/z 359.1589 m/z 343.1652

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m/z 519.1971 (+176) m/z 327.1693

m/z 385.1758 m/z 401.1710

m/z 341.1494 m/z 293.1636

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m/z 499.2047 (+16 +176) m/z 325.1901

m/z 371.1945 m/z 357.1804

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m/z 309.1598 m/z 323.1754

m/z 499.2075 (+176) m/z 515.2024 (H2+16+176, H4+176)

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m/z 533.2130 (H3+16+176, H30+176) m/z 357.1809 (H3+16, H4+2+16)

m/z 339.1703 m/z 337.1542

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m/z 367.1647 m/z 355.1683

m/z 293.1648 m/z 485.1918 (H23/ H26+16+176, H24-14+176)

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Figure S3.

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Figure S4.

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Figure S5.

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Figure S6.

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Figure S7.