ancer unc esern usraa arae ancer ran cee · a resus n run usce ss wc s asscae w wrse sca uncn ua e...

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www.cancerwa.asn.au Cancer Council Western Australia Collaborative Cancer Grant Scheme Project title Can creatine supplementation enhance the effects of weight training on muscle strength and mass in prostate cancer patients undergoing androgen deprivation therapy? Collaborators Dr Ciaran Fairman, A/Prof Raphael Chee, Dr Krissy Kendall and Mr Colin Tang Institutions Edith Cowan University; Genesis Cancer Care WA; Edith Cowan University; Sir Charles Gairdner Hospital Research description Androgen deprivation therapy is a common treatment for prostate cancer that results in profound muscle loss, which is associated with worse physical function, quality of life and poorer prognosis. Exercise is regularly used to combat this muscle wasting, but due to the severity of this condition, novel strategies to improve muscle mass are highly valuable. Creatine (Cr) is a naturally occurring substance in the body that plays an important role in providing energy. Cr has been shown to improve muscle mass in other clinical populations. The body has limited ability to produce Cr, so supplementation is regularly suggested to increase stores. The team will compare 12 weeks of weight training with or without Cr supplementation. They will take measures of muscle mass ,strength and physical function before and after training. The potential impact of this research is quite large. Results of this trial could inform clinicians of a novel strategy to combat muscle wasting in a population at great need. Funding from CCWA $20,000 from CCWA ($50,000 in total) Supported In the name of Swan Athletic Senior Citizens

Transcript of ancer unc esern usraa arae ancer ran cee · a resus n run usce ss wc s asscae w wrse sca uncn ua e...

www.cancerwa.asn.au

Cancer Council Western Australia Collaborative Cancer Grant Scheme

Project title Can creatine supplementation enhance the effects of weight training on muscle strength and mass in prostate cancer patients undergoing androgen deprivation therapy?

Collaborators Dr Ciaran Fairman, A/Prof Raphael Chee, Dr Krissy Kendall and Mr Colin Tang

Institutions Edith Cowan University; Genesis Cancer Care WA; Edith Cowan University; Sir Charles Gairdner Hospital

Research description Androgen deprivation therapy is a common treatment for prostate cancer that results in profound muscle loss, which is associated with worse physical function, quality of life and poorer prognosis. Exercise is regularly used to combat this muscle wasting, but due to the severity of this condition, novel strategies to improve muscle mass are highly valuable. Creatine (Cr) is a naturally occurring substance in the body that plays an important role in providing energy. Cr has been shown to improve muscle mass in other clinical populations. The body has limited ability to produce Cr, so supplementation is regularly suggested to increase stores. The team will compare 12 weeks of weight training with or without Cr supplementation. They will take measures of muscle mass ,strength and physical function before and after training. The potential impact of this research is quite large. Results of this trial could inform clinicians of a novel strategy to combat muscle wasting in a population at great need.

Funding from CCWA $20,000 from CCWA ($50,000 in total)

Supported In the name of Swan Athletic Senior Citizens