6 6

CC2.5

(( 66 ))

1. 1) 2)

1.

2.

3. ()

1.

v.s.

1.

2.

3.

5

Ex:

Ex:

1. defense system immune system immune system--

2. 1) 2)

()

3. 1) -- ()

2) 3) 4)

6

7

1.

1. 1) 2)

3)

(interferon)

1. 1) PH3-5

2) 1)

(lysozyme)

2)

3)

(Interferon)

2

1

mRNA

1. 1) 2) 19573)

a. 1. 2.

b.

11

(Complement proteins)(Complement proteins)

20

1. 20

2. 1) 2)

3)

4)

12

1. 1)

2)

(Neutrophils)

(Monocyte)

(Natural killer cell)

1.

1)

2)

3) killer cell

(Neutrophils)

60-70

1. : 60-70 %

2. 3.

() 4.

1.

(Monocyte)

5

1. --

2. 5%

17

1. 2.

(Natural killer cell)

(perforin) -B (granzyme B)

1. --

1)

2) T ()

a. b. B

(Inflammatory response)

(Histamine)

1. 1)

2) 2.

()

20

()

- (Lymphatic system)

1. 1)

2) 2.

1)

2) B B T T

1. B T

22

1.

1. 2.

3. (antigenic marker) (receptor)

1) ()

23

B cell

(humoralimmunity )

T cell

(cell-mediated immunity )

B cell and T cell

B cell

T cell

B cellT cells

1. 1) B (Bursa of Fabricius)

B B B

2) T T T (receptor)T

T

-2

T Cell-mediated

immunity

Humoral Immunity

B

T

APC

-1

-2

()

()

T

1. 1) T T T T

T T (Antigen-presenting cell, APC)T

2) T T T

3) T 4) B

(Antigen-presenting cell, APC)T

( APC)

()

T

T

APC()

TT

1. B

T

T (helper T cell, Th cell)

APC APC

(-2)

T (cytotoxic T cell)

1. T thymusT T

2. (, MHC) TcR T

3. T 1) 2) 3) -

B

27

T

1. T 1) T 2)

29

B cell

Th cell APC -2 () B

(plasma cell)-

(memory cell)

1. T (Th cell) APC Th cell APC -2 (B)B

1) (plasma cell)2) (memory cell)

A

B

B-

B ()

1. B B B B

32

B

1. B

(C) (V)

LightChain

HeavyChain

C C

C C

VV

VV

1. B 1) 4

2)

B

1. B 2. B

Y

X

X

X

X

1. 1) 2)

3)

()

()

1.

37

-

1.

1.

2. 3.

1. 1)

()

39

B

1.

1.

1.

()

Antigenicdeterminant

mast cell

B cell (plasma cell)

Mast cell

Histamine

B cells

(Allergy)

mast cell

(Allergen)

1. B IgE -- IgE

2. IgG, IgM, IgE, Ig, IgD

1) IgG

2) IgM-

3) IgA 4) IgE5) IgD

1.

2. --

44

1796 (1798)Edward Jenner, 1749~1823

(Vaccination)(Vaccination)

1796 Edward Jenner, 1749~1823 (cowpox)

4646

Page 46

Neil A. Campbell, Jane B. Reece, Lisa A. Urry, Michael L. Cain, Steven A. Wasserman, Peter V. Minorsky, Robert B. Jackson (2008). Biology . Eighth edition. Chapter 43.page930~951. San Francisco: Benjamin Cummings.

4747

Page 47

Discovery Discovery NHK (3)24-13B-HelperTCellsAnimm, Campbell, N. A., Reece, J. B. and Taylor, M. R. 2003. http://www.nanowerk.com/news/newsid=2561.php

48

44--11

49

44--22

50

44--33

51

44--44 2009/2/1

1943

John Vachon(w) for the United States Farm Security Administration

http://en.wikipedia.org/wiki/File:Typhoid_inoculation2.jpg

2002

Photo Credit: Content Providers(s): CDC Original uploader was Bryan Derksen at en.wikipedia http://en.wikipedia.org/wiki/File:Smallpox.jpg

/ http://commons.wikimedia.org/wiki/File:Edward_Je

nner.jpg

52

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WIKI -This image has been (or is hereby) released into the public domain by its author.

WIKI public domain

CC-Creative CommonsCC

53

PPTPPT

1. 2.

PPTCC2.5

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