3H-Indolium Salts Efficiently Prepared from N-Substituted Anilines and α-Branched Ketones by a...
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2004 Indole derivatives Indole derivatives R 0140 3H-Indolium Salts Efficiently Prepared from N-Substituted Anilines and α-Branched Ketones by a One-Pot Synthesis. — The Synthesis of indolium salts (III), (V) and their fused derivatives (VII) consists of a reaction sequence including nitrosation, zinc dust reduction, hydrazone formation and Fischer indolization, in which the isolation and purification of intermediates is not necessary. This one-pot syn- thesis starts from inexpensive and well accessible materials and provides well crystal- lized and easily separable salts with any desired anion. The scope and limitations of the method are discussed. — (ZIMMERMANN*, T.; BREDE, O.; J. Heterocycl. Chem. 41 (2004) 1, 103-108; Inderdiszip. Arbeitsgruppe Zeitaufgelöste Spektrosk., Fak. Chem. Mineral., Univ. Leipzig, D-04303 Leipzig, Germany; Eng.) — H. Hoennerscheid 29- 116
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Transcript of 3H-Indolium Salts Efficiently Prepared from N-Substituted Anilines and α-Branched Ketones by a...
2004 Indole derivatives
Indole derivativesR 0140 3H-Indolium Salts Efficiently Prepared from N-Substituted Anilines and
α-Branched Ketones by a One-Pot Synthesis. — The Synthesis of indolium salts (III), (V) and their fused derivatives (VII) consists of a reaction sequence including nitrosation, zinc dust reduction, hydrazone formation and Fischer indolization, in which the isolation and purification of intermediates is not necessary. This one-pot syn-thesis starts from inexpensive and well accessible materials and provides well crystal-lized and easily separable salts with any desired anion. The scope and limitations of the method are discussed. — (ZIMMERMANN*, T.; BREDE, O.; J. Heterocycl. Chem. 41 (2004) 1, 103-108; Inderdiszip. Arbeitsgruppe Zeitaufgelöste Spektrosk., Fak. Chem. Mineral., Univ. Leipzig, D-04303 Leipzig, Germany; Eng.) — H. Hoennerscheid
29- 116
