11/13/2017 Continue Shining On with Nature’s Trees, … 1 Continue Shining On with Nature’s...
Transcript of 11/13/2017 Continue Shining On with Nature’s Trees, … 1 Continue Shining On with Nature’s...
11/13/2017
1
Continue Shining On with Nature’s Trees, Leaves,
Fruit and B’s!
Cindy Klement, MS, CNS, MCHES
Ann Arbor, MI
Your Presenter:
Cindy Klement, MS, CNS, MCHES
• Master’s Degree in Nutrition
• Board-Certified Nutritionist
• Nationally Accredited Health Educator
• Adjunct Professor at Eastern Michigan University
• With NSP since 1982, instructor since 2004
• Co-Chair of Nature’s Institute & HPAC
Tonight’s Agenda
• The Power of Plant Oils – Eucalyptus, Orange Peel, Pine Needle
• New Blends for Refreshing, Renewing, Releasing and Prospering
• Mutated Genes and the Body’s Methylation Process
• Specials and Promotions
11/13/2017
2
Eucalyptus globulus leaf Essential Oil
• In 19th century England, eucalyptus oil was used in hospitals to clean urinary catheters
• Laboratory studies later showed that eucalyptus oil contains substances that kill bacteria
• It also may kill some viruses and fungi
• Studies show that eucalyptus oil acts as an expectorant, meaning it helps coughs by loosening phlegm
• Also used for bronchitis, coughs, and the flu
https://draxe.com/eucalyptus-oil-uses-benefits/
Orange Peel (Citrus sinesis) Essential Oil
• Orange contains stimulating and purifying qualities, making it ideal to support healthy immune system function
• Contains powerful antioxidants that help maintain overall health
• Decreasing the appearance of wrinkles
• Promotes a healthy complexion
• Energizes and uplifts the mind and body
https://draxe.com/orange-oil/
Pine Needle (Pinus sylvestris)
• Kills bacteria, fungi, yeast and pathogens
• Purifies the air
• Supports adrenals and times of hormonal changes for women
• Powerful respiratory support
• Latest studies looking at strong soothing and antioxidant constituents that can support cellular health and that of vital organs, including the brain, heart, liver and gut
https://draxe.com/pine-oil/
11/13/2017
3
Prosper Blend
Orange Peel (Citrus sinesis)
• Cedarwood Bark (Cedrus atlantica)
• Cinnamon Bark (Cinnamomum zeylanicum)
• Canadian Hemlock Leaf (Tsuga canadensis)
• Clove Bud (Eugenia caryophyllus)
• Lavender Flower (Lavandula angustifolia)
• Frankincense Gum Resin (Boswellia carterii)
• Myrrh Resin (Commiphora myrrha)
• Patchouli Leaf (Pogostemon cablin)
Atlas Cedarwood (Cedrus atlantica)
• Useful during times of chaos or conflict when one needs grounding to reflect on the situation, or to use during meditation to help change one’s perspective
• Improves wisdom and focus, centers oneself
• Improve personal outlook and self esteem
• Antifungal, antiseptic, diuretic, astringent, analgesic, and sedative properties - also an insecticide
• Used in skin and hair care, as a respiratory expectorant
• Detoxifier http://articles.mercola.com/herbal-oils/atlas-cedar-oil.aspx
Lawless J. The Illustrated Encyclopedia of Essential Oils. Rockport, MA: Element Books, 1995, 56-67.
Cinnamomum zeylanicum Leaf Oil
• Refreshes, revitalizes
• Brightens and uplifts the mood
• Healthy blood sugar is supportive of healthy weight
management and may help reduce cravings
• Warms and calms the digestion
• Stimulates healthy circulation and metabolismhttps://draxe.com/cinnamon-oil/
11/13/2017
4
Canadian Hemlock (Tsuga canadensis) Essential Oil
• Spiritually uplifting
• Anxiety, stress
• Skin cleansing properties
• Muscular aches
• Bronchitis, coughs, colds, flu
• Disinfectant properties used in household products, detergents, and soap, deodorants
Julia Lawless, The Illustrated Encyclopedia of Essential Oils (Rockport, MA: Element Books, 1995), 56-67.
https://www.fpl.fs.fed.us/documnts/usda/agib666/aib66601.pdf
Clove Bud (Eugenia caryophyllus) Essential Oil
• Boosts energy
• Powerful for the digestive system
• Supports immune system
• Helps repel insects, kills parasites
• Inflammatory conditions
• Used as a broad-spectrum antimicrobial
• Helpful for the skin and acne
• Kills mold and fungus
• Toothaches, reduces gum disease
https://draxe.com/clove-oil-uses-benefits/
Lavender (Lavandula angustifolia)
• Lavender is the most highly studied, safest, and least toxic of all essential oils
• Improves feeling of well being, supports mental alertness, suppresses situational anxiety, antibacterial, antifungal, stress, headaches, painful muscles, dysmenorrheal
Ali B, Al-Wabel NA, Shams S, Ahamad A, Khan SA, Anwar F. Essential oils used in
aromatherapy: A systemic review. Asian Pac J Trop Biomed. 2015;5(8):601–611.
11/13/2017
5
Lavender Essential Oil
• Hair loss, anxiety, canker sores, postoperative pain, cancer-related pain, postpartum complications, agitation, eczema, constipation, depression, dysmenorrhea, hypertension, insomnia, head lice, migraine headaches, ear pain, wound healing
http://naturaldatabase.therapeuticresearch.com/nd/Search.aspx?cs=&s=ND&pt=100&id
=838&ds=&name=Lavandula+angustifolia+(LAVENDER)&searchid=61794021
Frankincense Gum Resin (Boswellia carteri)
• Grounding, calming and relaxing without being sedating
• Used for stress, anxiety, mental peace, spiritual and emotional support
• Been shown to help lower cortisol levels• Headaches• Historically used for colic, flatulence, and as an
analgesic https://www.aromaweb.com/essential-oils/frankincense-oil.asp
Top 3 Essential Oils to Balance Hormones Naturally. Dr. Axe website. 2017. Accessed June 19, 2017. Available at: https://draxe.com/essential-oils-for-hormones/
Myrrh (Commiphora myrrha gum resin) Oil
• Well-being, strength, endurance
• Diffused for prayer or meditation
• Natural insect repellent
• Powerful immune support for the skin, lungs and mouth
• Ease pain of shingles
• Used as an oil pull for detoxificationhttps://draxe.com/myrrh-oil/
11/13/2017
6
Patchouli (Pogostemon cabin leaf) Oil
• Enhances mood
• Reduces insomnia
• Strengthens hair and skin, minimizes scars
• Emotionally balancing, reduces depression
• Boosts immune system - anti-fungal, anti-bacterial
• Reduces inflammation, fights fevers
• Insect repellanthttps://draxe.com/patchouli-oil/
Purity Refreshing Blend
• Lime Whole Fruit (Citrus aurantifolia)
• Lemon Peel (Citrus limon)
Canadian Hemlock Leaf (Tsuga canadensis)
• Lemongrass Leaf (Cymbopogon citratus)
• Citronella Leaf (Cymbopogon nardus)
Lavender Flowering Top (Lavandula x intermedia)
• Tea Tree Leaf (Melaleuca alternifolia)
• Peppermint Flower/Leaf (Mentha piperita)
Lime Peel (Citrus x latifolia) Oil
• Due to its antiviral, antibacterial, antiseptic properties, lime was used for fevers, infections, sore throats, colds
• Used to stimulate and refresh a tired mind, and help with depression
• Used as a remedy for scurvy in the 19th
century for British sailors and explorers spending long periods of time at sea
The Essential Homestead: Successfully Using Essential Oils in your Home,
Barnyard, and Beyond. Jill Winger. 2014.https://www.aromaweb.com/essential-oils/lime-oil.asp
11/13/2017
7
Lemon Peel (Citrus limon) Essential Oil
• Astringent and detoxifying properties
• Brightens and rejuvenates dull skin
• Controls nausea, vomiting
• Mood elevating properties
• Natural disinfectant – laundry, hands
• Wood and silver polish
Ali B, Al-Wabel NA, Shams S, Ahamad A, Khan SA, Anwar F. Essential oils used in aromatherapy: A systemic review. Asian Pac J Trop Biomed. 2015;5(8):601–611.https://draxe.com/lemon-essential-oil-uses-benefits/
Lemongrass (Cymbopogon citratus) Oil
• One of the most popular plant medicines in Brazil for nervous and digestive disorders
• In the Amazon it’s used as a sedative, for stomach problems, flu, pain, to curb perspiration, and keep insects at bay
• Used to cleanse oily skin, close pores, and to combat greasy hair
• Anti-fungal, insecticidal, antiseptic
https://draxe.com/lemongrass-essential-oil/
Citronella (Cymbopogon nardus) Leaf Oil
• Antiseptic, antimicrobial, antifungal, insecticidal
• Historically used to sanitize surfaces
• Promotes relaxation
• Fights respiratory infections
• Detoxification enhancer
• Protects against leaky gut and autoimmune diseases
• Calms barking dogs, keeps pets off furniture
https://draxe.com/citronella-oil/
11/13/2017
8
Tea Tree (Melaleuca alternifolia ) Essential Oil
• Antimicrobial activity
• A favourite for home cleaning recipes and laundry soap addition
• Popular for application to skin blemishes, eruptions and rashes
• May apply neat to feet and toenails after showering, working out, or swimming
• Add to shampoo or conditioner to promote a healthy scalp and hair
• Used for colic, earache, toothache, headache, and cramping pain
• Bundjalung in Australia – coughs, colds, sore throatshttps://draxe.com/tea-tree-oil-uses-benefits/
Peppermint (Mentha piperita) Flower/Leaf Oil
• Anti inflammatory, analgesic, anti spasmodic,
• Anti fungal, -bacterial, -viral
• Energizer
• Reduces cravings, nausea, fevers
• Sinus and allergy relief
• Bug repellant
• Bloating and indigestion
• Freshens breath
Ali B, Al-Wabel NA, Shams S, Ahamad A, Khan SA, Anwar F. Essential oils used in aromatherapy: A systemic review. Asian Pac J Trop Biomed. 2015;5(8):601–611.
Renew Releasing Blend
• Grapefruit Peel (Citrus paradisi)
Lemon Peel (Citrus limon)
• Rosemary Leaf (Rosmarinus officinalis)
• Cypress Leaf (Cupressus sempervirens)
• Juniper Fruit (Juniperus communis)
• Laurel Leaf (Laurus nobilis)
11/13/2017
9
Grapefruit Peel (Citrus x paradisi) Oil
• Uplifting, energizing, cleansing
• Reduces depression
• Immune system support
• Asthma, eczema, lice
• Decreases fluid retention, curbs sugar cravings, helps with weight loss
• Isn’t too strong or overpowering and is great to diffuse with other energizing oils, like rosemary, because it lightens up and sweetens the blend
https://www.aromaweb.com/essential-oils/grapefruit-oil.asp
Rosemary (Rosmarinus officinalis) Essential Oil
• Excellent skin tonic properties
• Soothing positive effect on menstrual cramps
• Stimulate for the scalp encouraging hair growth
• Improves memory
• Liver detoxification and gallbladder function
• Balances microflora in the gut
• Lowers cortisol levels
Ali B, Al-Wabel NA, Shams S, Ahamad A, Khan SA, Anwar F. Essential oils used in aromatherapy: A systemic review. Asian Pac J Trop Biomed. 2015;5(8):601–611.
Cypress (Cupressus sempervirens)
• Hippocrates used it to treat hemorrhoids
• 17th century England used for infertility
• Greek name sempervirens means ‘ever living’
• Cypress is also known as the "drama tree" because of its tendency to bend with even the slightest of breezes
• Used in religious rituals to calm the mind, or to assist one in recovering from loss
Historical Research. 2014;87(237):423-443. Jennifer Evans University of Hertfordshire,
Institute of Historical Research, University of London School of Advanced Study. http://ayurvedicoils.com/tag/health-benefits-of-cypress-oil
11/13/2017
10
Cypress Essential Oil
• Tired or need help with concentration
• Headaches, relaxes muscles
• Detoxify and decongest lymphatic system
• Head colds, cough, bronchitis and as an expectorant
Buckle J, Ryan K, Chin KB. Clinical aromatherapy for pregnancy, labor and postpartum. International Journal of Childbirth Education. 2014;29(4):21-29.
Tillett J, Ames D. The Uses of Aromatherapy in Women’s Health. Jackie Tillett, ND, CNM, J Perinat Neonat Nurs. 2014;24(3)238–245.https://www.aromaweb.com/essential-oils/cypress-oil.asp
Using God’s Medicine for the Abundant Life: An Evidence-Based Approach to Essential Oils. Eric L. Zielinski, DC, MPH, 2015.Elansary HO, Salem MZM, Ashmawy NA, Yacout MM. Chemical Composition, Antibacterial and Antioxidant Activities of Leaves Essential Oils from Syzygium cumini L., Cupressus sempervirens L. and Lantana camara L. from Egypt. Journal of Agricultural Science. 2012;4(10):144-153.
http://naturaldatabase.therapeuticresearch.com/nd/Search.aspx?cs=&s=ND&pt=100&id=421&ds=
Juniper (Juniperus communis) Essential Oil
• Relieves bloating, boosts digestion, used for heartburn and acid reflux
• Skin problems: rashes, eczema, acne, foot odours, fungus
• Relaxant and sleep aid
• Insect repellent
• Natural antiseptic
https://draxe.com/juniper-berry-essential-oil/
Bay Laurel (Laurus nobilis) Essential Oil
• The ancient Greeks believed that laurel was effective against contagious disease
• Carminative, expectorant, diuretic, sudorific
• Flatulence, difficult digestion
• Asthma and bronchitis
• Flu, fevers, virus infections
• Discourages insects in the home
• Relaxation, rheumatic aches and pains, stiff neck, loss of hair after an infection
http://aromatherapybible.com/laurel/
11/13/2017
11
A Few Precautions:
• Cypress – those sensitive to cedar or peaches may have allergic responses
• Lime - photosensitivity might occur
• Grapefruit - major interactions with 29 pharmaceutical medications with moderate interactions occurring on another 26 Rx; it is also contraindicated in hormone-sensitive cancers
Available through Sound Concepts at www.naturestools.com
Rehydrating the Skin
• NSP’s new all-natural lotion is designed to be both a stand-alone hand and body lotion AND a perfect base for blending, mixing and preparing NSP’s Authentic Essential Oils for a wide range of applications
• Olive oil, sunflower seed oil, coconut oil, macadamia seed oil, purified water, glycerin, oat protein, shea butter, aleurites moluccana nut seed oil
Unscented, Safe, Non-Allergenic
EWG’s Skin Deep Cosmetics Database Safety Score:
• Cetearyl alcohol - 1
• Caprylic/capric triglyceride - 1
• C13-15 Alkane - 1
• Pentylene glycol - 1
• Glyceryl stearate - 1
• Potassium olivoyl - 1
• Microcrystalline cellulose – 1
• Behenyl alcohol - 1
• Hydroxyacetophenone - 1
• Benzyl alcohol - 5
• Xanthan gum, cellulose gum -
• Sodium phytate and sodium hyaluronate - 1
11/13/2017
12
• New Single Oils – Eucalyptus, Orange, and Pine Needle
• New Blends – Prosper, Purity, and Renew
• New Hand and Body Lotion
• A biochemical pathway that manages or contributes to a wide range of crucial bodily functions, including:
• Endothelial function
• Energy production
• Neurotransmitters and the balancing of brain chemistry affecting cognition and mood; stress (fight-or-flight) response
• Production and recycling of glutathione - the body's master antioxidant, thus repairing cells damaged by free radicals
• Detoxification of hormones, chemicals and heavy metals
• Immune response: T-cell production, fighting infections and viruses
Switch Gears - The Methylation Cycle
MTHFR Gene
• MTHFR is a very important enzyme in the body necessary for methylation to occur
• This gene provides instructions for making an enzyme called methylenetetrahydrofolate reductase
• The MTHFR gene mutation was discovered during the completion of the Human Genome Project
11/13/2017
13
All Humans Have the Same Set of Genes
• These variations influence not only how you look, but also how your body reacts differently to external factors - especially the foods you eat and lifestyle you live
• We all have certain genetic variations or “defects” that can influence our health and how we metabolize and use certain nutrients
The Animated Genome from the SmithsonianNational Museum of Natural History
The Most Well-Studied MTHFR Variations
• The two main mutations of the MTHFR gene are C677T and A1298C
• MTHFR C677T mutations are tied to cardiovascular problems, elevated homocysteine levels, stroke, migraines, miscarriages and neural tube defects
• MTHFR A1298C mutations are tied to higher levels of fibromyalgia, IBS, fatigue, chronic pain, schizophrenia and mood-related problems
Common MTHFR Variations
This brief list helps to make more sense of the entire concept:
• MTHFR C677C = normal (green)
• MTHFR C677T = one copy (blue)
• MTHFR T677T = two copies (yellow)
• MTHFR A1298A = normal (green)
• MTHFR A1298C = one copy (blue)
• MTHFR C1298C = two copies (yellow)
11/13/2017
14
Prevalence of MTHFR Gene VariationsAmong Ethnic Groups
EthnicityMTHFR Variant Frequency
C677T A1298C
Caucasian 24-37% 29-37%
Hispanic 31-48% 15-24%
African American 8-15% 12-19%
Asian Indian 10% 27%
Asian – Chinese, Japanese, Korean 33-51% 15-25%
MTHFR Mutation Symptoms and Signs
Although researchers still aren’t entirely sure which diseases and disorders an MTHRF mutation might contribute to most, evidence exists that the following health problems are tied to one of two primary forms of genetic MTHFR mutation:
• Autism
• ADHD
• Down syndrome
• Depression and anxiety
• Spina bifida
• Schizophrenia
• Bipolar disorder
• Autoimmune disorders
• Addictions (alcohol and drug dependence, for example)
• Chronic fatigue and pain disorders
• Heart problems, including strokes, low HDL “good” cholesterol levels and high homocysteine levels
• Hormonal problems and fertility problems, including miscarriages and PCOS
• Pulmonary embolisms
• Fibromyalgia
• Migraines
• Diabetes, Cancer
MTHFR Mutation Symptoms and Signs
11/13/2017
15
• Digestive problems, including IBS
• Parkinson’s disease and Alzheimer’s disease
• Allergies, immune dysfunction
• Premature aging
• Miscarriages, fertility, and problems in pregnancy including preeclampsia and postpartum depression
MTHFR Mutation Symptoms and Signs
Folic Acid Enrichment
It is so effective that the addition of folic acid back into flour, processed
cereals and crackers is now mandatory in Australia, the USA, Canada
and several other countries
Folic Acid Can Be Problematic
• This is a big problem for people who don’t metabolize folic acid well
• The recommended daily intake for folic acid is 400 mcg, yet un-metabolized folic acid already appears in the blood when we consume just 200 mcg per day
• Folic acid added to processed foods can cause a build-up in the body leading to toxicity --some studies even showed it increased cancer risk
11/13/2017
16
Who is at Risk for Folic Acid Deficiency?
• Those with a dietary deficiency
• Modest alcohol intake - 1 drink/day inhibits the absorption of folic acid
• Individuals with malabsorption or GI disorders: Celiac disease, Crohn’s disease, for instance
• Pregnant women and those of childbearing age: Folic acid is most effective when taken prior to conception to prevent neural tube defects and other birth defects
Active Folate and Pregnancy
• Conventional folic acid supplements are likely not protective of your child if it remains inactivated in your blood stream
• Active folate (L-methyl folate) is highly protective against neural tube defects
• Reduction of implantation failure
• Reduction in incidence of early (1st trimester) miscarriages
• Reduction in anemia
• Reduction in pregnancy-induced headaches
• Reduction in preterm birth
• Reduction in postpartum blood clots
• Prevention of neural tube defects (NTDs) and other birth defects (congenital heart disease, urinary tract anomalies, oral facial clefts, limb defects, and pyloric stenosis)
• Reduction in language delay in offspring
Benefits of Folic Acid for Mothers and Infants
https://ods.od.nih.gov/factsheets/Folate-HealthProfessional
11/13/2017
17
More Folate in the Diet = More Opportunities to Create the Active Form
• The body easily recycles leftover folate into a harmless compound, whereas it cannot always do so with folic acid
• Without getting into more chemistry, that is why folic acid can easily accumulate in the blood
Consume High Folate Foods
• Beef liver (3 ounces = 215 mcg)
• Okra (1/2 cup = 135 mcg)
• Beans and lentils (1/2 cup = 130 mcg)
• Raw spinach (1 cup = 110 mcg)
• Asparagus (5 spears = 100 mcg)
• Mustard greens, turnip greens (1/2 cup = 85 mcg)
• Brussels sprouts (1/2 cup = 80 mcg)
• Strawberries (8 = 80 mcg)
Dark leafy greens contain the methylated form of folate that those with a gene defect need
• Coronary heart disease, high blood pressure, endothelial dysfunction, thrombophilia (increased tendency to excessive blood clotting)
• Depression and reduced efficacy of antidepressants
• Age-related dementia, Alzheimer’s disease
• Osteoporosis
• Male infertility
Diseases Associated with Folic Acid Deficiency
https://ods.od.nih.gov/factsheets/Folate-HealthProfessional
Coppen A, Bolander-Gouaille C. Treatment of depression: time to consider folic acid and vitamin B12. J
Psychopharmacol 2005,19(1): 59-65.
11/13/2017
18
Vitamin B9
• Folate, an essential micronutrient, is a critical cofactor in metabolism
• Folic acid is a synthetic form of vitamin B9 (folate)
• Mammals cannot produce folate and depend on diet and supplementation to maintain normal levels
• External supplementation of folate may occur as folic acid, folinic acid or 5-methyltetrahydrofolate (5-MTHF)
Scaglione F, Panzavolta G. Xenobiotica. 2014 May;44(5):480-8.
Folic Acid and 5-MTHF Are NOT Equivalent
• Naturally occurring 5-MTHF is well absorbed, even when gastrointestinal pH is altered, and its bioavailability is not affected by metabolic defects
• Use of 5-MTHF also prevents the potential negative effects of unconverted folic acid in the peripheral circulation
• Using 5-MTHF instead of folic acid reduces interactions with pharmaceutical drugs, overcomes defects caused by the MTHFR mutation, and reduces the potential for masking vitamin B12 deficiency
Scaglione F, Panzavolta G. Xenobiotica. 2014 May;44(5):480-8.
B12 is Essential in Many Biological Processes
• Methylation
• Synthesis of methionine
• Synthesis of folic acid
• Red blood cell production
• Nerve cell growth and function
• Neurotransmitter metabolism
• DNA synthesis
• Epigenetic gene expression
11/13/2017
19
Vitamin B12
The largest and most complicated B
vitamin, B12 is naturally produced by
bacteria in the intestines
Age Daily1 – 3 years .9 mcg
4 – 8 years 1.2 mcg
9 – 14 years 1.8 mcg
14+ years 2.4 mcg
Pregnant 2.6 mcg
Lactating 2.8 mcg
https://www.healthlinkbc.ca/health-topics/hw65706https://www.healthlinkbc.ca/health-topics/hw65706
Food Sources of Vitamin B12
https://ods.od.nih.gov/factsheets/Vitamin%20B12-HealthProfessional
Who is at Risk for a Vitamin B12 Deficiency?
• Vitamin B12 is common, being present in 10-40% of the population
• Individuals with malabsorption or GI disorders: Celiac disease, Crohn’s disease, for instance, as well as h. pylori infections
• Vegan and vegetarian diets
• Gastric surgery and medications (H2 blockers, proton pump inhibitors)
• Pregnant, lactating women and their infants: can lead to severe and permanent neurological damage
• Deficiencies can be masked by taking a folic acid supplement!
https://ods.od.nih.gov/factsheets/Vitamin%20B12-HealthProfessional
11/13/2017
20
Diseases Associated with Vitamin B12 Deficiency
• Coronary heart disease, high blood pressure and endothelial dysfunction
• Pernicious anemia
• Age-related dementia, Alzheimer’s disease
• Peripheral neuropathy
• Psychiatric disease
• Autistic Spectrum Disorders
https://ods.od.nih.gov/factsheets/Vitamin%20B12-HealthProfessional
Cyanocobalamin (typically synthetic)
Methylcobalamin is the active form of vitamin B12
• When taken orally, methylcobalamin has a higher
bioavailability than cyanocobalamin
• Shows a longer retention in tissues than
cyanocobalamin
Cyanocobalamin and Methylcobalamin are NOT Equivalent
Thakkar, K., Billa, G.. Treatment of vitamin B12 deficiency - Methylcobalamine?
Cyancobalamine? Hydroxocobalamin? - Clearing the confusion. Eur. J. Clin. Nutr. 2015, 69, 1–2.
Methionine
Cyanocobalamin
Cob(III)alamin
Cob(II)alamin
THF
DHF
5,10-MTHF
Folic Acid
THF
5,10-MTHF
FolateCycle
B12 Cycle
Cobalamin
Methyl Combo
Typical FolateSupplement
Typical B12Supplement
MTHFR
MTHFR
Serine hydroxymethyl
transferase
DHFR
DHFR
Decyanation by MMACHC
Cobalt Reduction
Homocysteine methyl
transferase
MethionineSynthase
Methionine Synthase
Reductase
Homocysteine
Methylfolate Methylcobalamin
11/13/2017
21
MTHFR Tips
• It is important to focus on gut health so that the body can absorb the nutrients from food as effectively as possible, especially when the body has an impaired ability to use certain nutrients
• Support the gut with fermented foods and probiotics -- this also helps avoid candida, which can make MTHFR-related problems worse
Avoid Environmental Toxins
• Those with an MTHFR gene defect have an impaired ability to eliminate toxins
• As much as possible, they need to avoid plastics, antibacterial soaps, chemicals in personal care products and cleaning products, and scented candles, which can all release harmful chemicals
Reduce Anxiety and Depression
• Omega-3 fatty acids help reduce inflammation and are beneficial for cognitive health
• Exercise helps to improve hormonal balance and sleep quality
• Essential oils are soothing and can help to elevate moods, detoxify the body, and create better sleep while reducing stress
11/13/2017
22
AVOID “Fortified” and “Enriched” Foods
• Spaghetti – enriched (1 cup = 127 mcg)
• Macaroni – enriched (1 cup = 172 mcg)
• Rice – enriched (1 cup = 307 mcg)
• Bagel (4” – 119 mcg)
• Breakfast cereals – vary based on brand – check food label
Boost Detoxification
• Eliminate use of recreational drugs and reduce alcohol intake, both of which can make symptoms worse by interfering with methylation
• Avoid Heavy Metals: They are harder to remove from the body for those with the MTHFR gene defect
• Help a Body Out: Since those with an MTHFR defect have an impaired ability to eliminate toxins, support the body with detox baths, perspiration (exercise and sauna), drinking lots of water, and skin brushing
Boost Detoxification
• Only use natural beauty and household products that are free from harsh chemicals
• Consume fresh fruits and vegetables to increase antioxidant intake
• Cleanse daily with Liquid Green Drink
• Do quarterly cleansing with 14-day Berry Flavoured Cleanse
11/13/2017
23
Get Enough Quality Sleep
Make it a priority to get 7-9 hours every night, sticking to a regular schedule as much as possible
– Create a relaxing bedtime routine
– Stay off of electronic devices
– Read something soothing
– Cool your bedroom a bit, and make it dark
L-methyl folate
• Aside from cutting your intake of fortified and enriched flour products, folic acid supplements can be replaced with the active form L-methyl folate
• It bypasses any MTHFR defects and is shown to be equally (if not more) effective at increasing plasma folate levels and reducing homocysteine concentrations
• L-methyl folate is also better absorbed and interacts with fewer medications than folic acid
Discuss Medications with Your Doctor
Some medications can further deplete already low folate levels or interfere with methylation and make symptoms worse:
– Antibiotics
– Birth control pills
– Hormone replacement therapy drugs
– Anticonvulsants
– Antacids
– NSAID pain relievers
– Antidepressants
– Chemotherapy treatments
– Cholesterol-lowering drugs
– Blood pressure medications
– Metformin
11/13/2017
24
Summary
• MTHFR mutations are caused from inheriting one or more mutated genes that interfere with the normal process of methylation, folate conversion, and enzyme production
• Multiple health conditions have been associated with MTHFR mutations
Summary
• Factors that can make MTHFR mutation symptoms worse include:
• Eating a poor diet
• Folic acid in enriched foods
• Leaky gut syndrome/poor absorption
• Imbalanced gut microbiome
• Malnutrition
• Gastrointestinal illness
• High amounts of stress
• Alcohol and drug use
• Toxin exposure
Summary
Natural treatments and ways to manage MTHFR symptoms include:
• Improving gut health
• Protecting heart health
• Getting more natural folate in the diet
• Acquiring methylated B2, B3, and B6 vitamins
• Lowering intake of inflammatory foods
• Supplementing with L-methyl folate with vitamin B12
• Managing stress
• Exercising
• Getting enough sleep
11/13/2017
25
How Can We Get the Right Kind of Folate?
• Methyl Combo is a powerful blend of Methyl B12 and Methyl Folate using the most biologically active forms of these nutrients
Methyl Combo
• Contributes to the maintenance of normal neurological and psychological functions
• Contributes to a reduction in tiredness and fatigue
• Supports the nervous and immune systems
• Provides nutrients essential for prenatal development
• Supports general well-being
Doesn’t Folate Mask a B12 Deficiency?
• Folic acid works in conjunction with Vitamin B12
• Also, folic acid supplementation can mask a B12 deficiency
• The NEW Liquid – Methyl Vitamin B12 Complete contains 1,000 mcg of Vitamin B12 in the form of methylcobalamin, which is the biologically active form used by the body
11/13/2017
26
Liquid – Methyl Vitamin B12 Complete
• Promotes energy
• Contributes to overall central nervous system function
• Supports the immune system
• Liquid B vitamins may be especially important for vegetarians since dietary sources of vitamin B12 are mostly foods of animal origin
Imbed Video Here of New Methyl Products that was shown at Convention
Avoid Potential Methyl folate Side Effects
• Start slowly
• Personalize, and trust your body and symptoms
• Expect some adjustment, pulse your dose
• Remember that methyl folate is something your body actually needs, and has been compensating for, so it’s important to find a way to take it
• Remember also that you are allowing your body to start to catch up on detoxification and repair, which can also increase your level of inflammation while things are being sorted out
11/13/2017
27
Decrease Potential Methyl folate Side Effects
• Side effects may include:
– Mood changes: depression, irritability, severe anxiety
– Pain: sore muscles, joint aches, headaches, migraines
– Physical Symptoms: rash, acne, heart palpitations, nausea, insomnia
• Anti-inflammatories can help decrease symptoms and help the body to adjust:
– Curcumin with bioperine
– Omega-3 fatty acids
– Extracts of green tea
– Cat’s claw herb
– A blend of super antioxidants
Lab Testing for MTHFR
• https://www.23andme.com/en-ca/ entire genome for $249
• https://www.ancestry.com
• www.promethease.com $10 uploads raw data for you to actually read!
References
• National Institutes of Health, US National Library of Medicine, Genetics Home Reference: https://ghr.nlm.nih.gov/gene/MTHFR#sourcesforpage
• National Institutes of Health, US National Library of Medicine, PubMed https://www.ncbi.nlm.nih.gov/pubmed/11683544 andhttps://www.ncbi.nlm.nih.gov/pubmed/22492374
• Dr. Ben Lynch http://mthfr.net/mthfr-research/2012/01/27/
• Primary Psychiatry http://primarypsychiatry.com/the-role-of-l-methylfolate-in-depressive-disorders-commentary/ and http://primarypsychiatry.com/l-methylfolate-methylcobalamin-and-n-acetylcysteine-in-the-treatment-of-alzheimeras-diseasearelated-cognitive-decline/
• British Medical Journal http://www.bmj.com/content/328/7455/1535
• Dr. Josh Axe https://draxe.com/mthfr-mutation/
• Diet vs Disease https://www.dietvsdisease.org/
11/13/2017
28
21st Century Health Care
WE CAN CHANGE THE WORLD!
The More We Know, the More We Can Transform Lives and Reduce Suffering!