Post on 14-Apr-2018
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Peptic Ulcers
What I need to know about
Peptic Ulcers
NATIONAL INSTITUTES OF HEALTH
National Digestive Diseases Information Clearinghouse
U.S. Department
of Health and
Human Services
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What I need to know
about Peptic Ulcers
NATIONAL INSTITUTES OF HEALTH
National Digestive Diseases Information Clearinghouse
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Contents
What is a peptic ulcer? ........................................... 1What are the symptoms of peptic ulcers? ............. 2
What causes peptic ulcers? .................................... 4
Do stress or spicy foods cause peptic ulcers? ....... 5
What increases my risk of getting pepticulcers? ...................................................................... 6
Can peptic ulcers get worse? ................................. 7
How can I find out whether I have pepticulcers? ...................................................................... 8
How are peptic ulcers treated? ............................. 9Can I use antacids? ............................................... 10
Can peptic ulcers come back? ............................. 11
What happens if peptic ulcers dont heal?Will I need surgery? .............................................. 11
What can I do to prevent peptic ulcers? ............. 12
What can I do to lower my risk of gettingpeptic ulcers? ......................................................... 12
Glossary ................................................................. 13
For More Information .......................................... 13
Acknowledgments ................................................ 14
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What is a peptic ulcer?
A peptic ulcer is a sore in the lining of yourstomach or duodenum.* The duodenum is thefirst part of your small intestine. If peptic ulcersare found in the stomach, theyre called gastriculcers. If theyre found in the duodenum, theyrecalled duodenal ulcers. You can have more than
one ulcer.Many people have peptic ulcers. Peptic ulcers canbe treated successfully. Seeing your doctor is thefirst step.
Peptic ulcers occur in the wall of the stomach andduodenum.
Ulcer
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*Words in bold type are defined in the glossary onpage 13.
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What are the symptoms of pepticulcers?
A burning pain in the gut is the most commonsymptom. The pain
G feels like a dull ache
G comes and goes for a few days or weeks
G starts 2 to 3 hours after a meal
G comes in the middle of the night when yourstomach is empty
G usually goes away after you eat
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A burning pain in the gut is a commonsymptom of peptic ulcers.
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Other symptoms are
G losing weight
G not feeling like eating
G having pain while eating
G feeling sick to your stomach
G vomiting
Some people with peptic ulcers have mildsymptoms. If you have any of these symptoms,
you may have a peptic ulcer and should see yourdoctor.
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What causes peptic ulcers?
Peptic ulcers are caused byG bacteria calledHelicobacter pylori, orH. pylori
for short
G nonsteroidal anti-inflammatory drugs (NSAIDs)such as aspirin and ibuprofen
G other diseases
Your body makes strong acids that digest food.A lining protects the inside of your stomach andduodenum from these acids. If the lining breaksdown, the acids can damage the walls. Both
H. pylori and NSAIDs weaken the lining so acidcan reach the stomach or duodenal wall.
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Nonsteroidal anti-inflammatorydrugs can cause peptic ulcers.
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H. pylori causes almost two-thirds of all ulcers.Many people haveH. pylori infections. But not
everyone who has an infection will develop a pepticulcer.
Most other ulcers are caused by NSAIDs. Onlyrarely do other diseases cause ulcers.
Do stress or spicy foods causepeptic ulcers?
No, neither stress nor spicy foods cause ulcers. Butthey can make ulcers worse. Drinking alcohol or
smoking can make ulcers worse, too.
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What increases my risk of gettingpeptic ulcers?
Youre more likely to develop a peptic ulcer if you
G have anH. pylori infection
G use NSAIDs often
G smoke cigarettes
G drink alcohol
G have relatives who have peptic ulcers
G are 50 years old or older
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Having relatives with peptic ulcers puts you at risk ofhaving them too.
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Can peptic ulcers get worse?
Peptic ulcers will get worse if they arent treated.Call your doctor right away if you have any of thesesymptoms:
G sudden sharp pain that doesnt go away
G black or bloody stools
G bloody vomit or vomit that looks like coffeegrounds
These could be signs that
G the ulcer has gone through, or perforated, thestomach or duodenal wall
G the ulcer has brokena blood vessel
G the ulcer has stoppedfood from movingfrom the stomach
into the duodenum
These symptoms mustbe treated quickly.You may need surgery.
7
Call your doctor if the paingets worse.
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How can I find out whether I havepeptic ulcers?
If you have symptoms, see your doctor. Yourdoctor may
G take x rays of your stomach and duodenum,called an upper GI series. Youll drink a liquidcalled barium to make your stomach andduodenum show up clearly on the x rays.
G use a thin lighted tube with a tiny camera onthe end to look at the inside of your stomachand duodenum. This procedure is called anendoscopy. Youll take some medicine to relax
you so your doctor can pass the thin tubethrough your mouth to your stomach andduodenum. Your doctor may also remove atiny piece of your stomach to view under amicroscope. This procedure is called a biopsy.
If you do havea peptic ulcer,your doctor maytest your breath,blood, or tissueto see whether
bacteria causedthe ulcer.
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Peptic ulcers can show up on x rays.
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How are peptic ulcers treated?
Peptic ulcers can be cured. Medicines for pepticulcers are
G proton pump inhibitors or histamine receptorblockers to stop your stomach from making acids
G antibiotics to kill the bacteria
Depending on your symptoms, you may take oneor more of these medicines for a few weeks.Theyll stop the pain and help heal your stomachor duodenum.
Ulcers take time to heal. Take your medicines
even if the pain goes away. If these medicinesmake you feel sick or dizzy, or cause diarrheaor headaches, your doctor can change yourmedicines.
If NSAIDs caused your peptic ulcer, youll need tostop taking them. If you smoke, quit. Smoking
slows healing of ulcers.
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Can I use antacids?
Yes. If you have a peptic ulcer, taking antacids willG stop the acids from working and reduce the pain
G help ulcers heal
You can buy antacids at any grocery store or drug-store. But you must take them several times a day.
Also, antacids dont kill the bacteria, so your ulcercould come back even if the pain goes away.
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Antacids can reduce pain and help ulcers heal.
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Can peptic ulcers come back?
Yes. If you stop taking your antibiotic too soon,not all the bacteria will be gone and not all thesores will be healed. If you still smoke or takeNSAIDs, your ulcers may come back.
What happens if peptic ulcers dontheal? Will I need surgery?
In many cases, medicine heals ulcers. You mayneed surgery if your ulcers
G
dont healG keep coming back
G perforate, bleed, or obstruct the stomach orduodenum (see page 7)
Surgery can
G remove the ulcers
G reduce the amount of acid your stomach makes
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What can I do to prevent pepticulcers?G Stop using NSAIDs. Talk with your doctor about
other pain relievers.
12
What can I do to lower my risk ofgetting peptic ulcers?G Dont smoke.
G Dont drink alcohol.
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Glossary
Barium(BAIR-ee-um): A chalky liquid used tocoat the inside of organs so that they will show
up on an x ray.
Biopsy (BYE-op-see): Removing a small piece oftissue to view under a microscope.
Duodenum (doo-AW-deh-num): The first part ofyour small intestine, right after your stomach.
Endoscopy (en-DAH-skoh-pee): A test to lookinside the stomach and small intestine. Thedoctor uses a thin, flexible tube that contains alight and a tiny video camera. This device is
called an endoscope.
Helicobacter pylori (HELL-ih-koh-BAK-turpy-LOH-ree): A bacterium that can damagestomach and duodenal tissue, causing ulcers.It is known asH. pylori for short.
For More Information
You can get information about peptic ulcers fromthe
Centers for Disease Control and Prevention
1600 Clifton RoadAtlanta, GA 30333Phone: 1888MYULCER or (404) 6393534Internet: www.cdc.gov
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Acknowledgments
The National Digestive Diseases InformationClearinghouse (NDDIC) would like to thank thefollowing individuals for assisting with scientificand editorial review of this publication.
David A. Peura, M.D.University of Virginia
Steven J. Czinn, M.D.Case Western University
Thanks also to Anne Barker, R.N., B.S.N., at theHealth Alliance, Columbia, MD, for facilitatingfield-testing of this publication.
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National Digestive DiseasesInformation Clearinghouse
2 Information WayBethesda, MD 208923570Phone: 18008915389Fax: (703) 7384929Email: nddic@info.niddk.nih.govInternet: www.digestive.niddk.nih.gov
The National Digestive Diseases InformationClearinghouse (NDDIC) is a service of the NationalInstitute of Diabetes and Digestive and Kidney Diseases(NIDDK). The NIDDK is part of the National Institutesof Health under the U.S. Department of Health andHuman Services. Established in 1980, the clearinghouseprovides information about digestive diseases to people
with digestive disorders and to their families, health careprofessionals, and the public. NDDIC answers inquiries,develops and distributes publications, and works closelywith professional and patient organizations andGovernment agencies to coordinate resources aboutdigestive diseases.
Publications produced by the clearinghouse are carefullyreviewed by both NIDDK scientists and outside experts.
This publication is not copyrighted. The clearinghouseencourages users of this booklet to duplicate anddistribute as many copies as desired.
This booklet is also available atwww.digestive.niddk.nih.gov.
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U.S. DEPARTMENT OF HEALTHAND HUMAN SERVICESNational Institutes of Health
National Institute of Diabetes andDigestive and Kidney Diseases